Homo sapiens

0 known processes

IFNA4

interferon, alpha 4

(Aliases: IFN-alpha4a,MGC142200,INFA4)

IFNA4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of peptidyl serine phosphorylation of stat protein GO:0033139 3 0.918
negative regulation of interleukin 13 secretion GO:2000666 1 0.881
positive regulation of peptidyl serine phosphorylation of stat protein GO:0033141 3 0.818
negative regulation of t helper 2 cell cytokine production GO:2000552 2 0.799
negative regulation of interleukin 5 secretion GO:2000663 1 0.612
interleukin 13 secretion GO:0072611 2 0.376
negative regulation of interleukin 5 production GO:0032714 3 0.308
regulation of t helper 2 cell cytokine production GO:2000551 2 0.293
regulation of interleukin 5 secretion GO:2000662 2 0.289
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.170
negative regulation of type 2 immune response GO:0002829 3 0.155
positive regulation of cellular amine metabolic process GO:0033240 7 0.134
negative regulation of t cell cytokine production GO:0002725 4 0.091
regulation of cellular ketone metabolic process GO:0010565 50 0.086
t helper 2 cell cytokine production GO:0035745 3 0.086
cellular amino acid metabolic process GO:0006520 116 0.084
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.083
regulation of cellular amino acid metabolic process GO:0006521 6 0.083
regulation of interleukin 13 secretion GO:2000665 2 0.079
cellular amine metabolic process GO:0044106 41 0.067
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.065
regulation of cell cycle GO:0051726 393 0.065
response to other organism GO:0051707 261 0.063
natural killer cell activation involved in immune response GO:0002323 2 0.060
response to organic cyclic compound GO:0014070 204 0.057
response to cytokine GO:0034097 232 0.055
interleukin 5 secretion GO:0072603 2 0.055
response to virus GO:0009615 126 0.054
regulation of secretion GO:0051046 194 0.054
serine phosphorylation of stat protein GO:0042501 4 0.053
regulation of cellular amine metabolic process GO:0033238 11 0.052
regulation of protein transport GO:0051223 213 0.052
response to biotic stimulus GO:0009607 276 0.052
immune response GO:0006955 307 0.052
cellular ketone metabolic process GO:0042180 80 0.050
post embryonic development GO:0009791 2 0.049
innate immune response GO:0045087 178 0.048
amine metabolic process GO:0009308 44 0.048
regulation of secretion by cell GO:1903530 177 0.047
response to external biotic stimulus GO:0043207 261 0.045
positive regulation of phosphorylation GO:0042327 394 0.043
secretion GO:0046903 254 0.042
system process GO:0003008 349 0.042
viral process GO:0016032 146 0.041
g protein coupled receptor signaling pathway GO:0007186 207 0.040
negative regulation of multicellular organismal process GO:0051241 317 0.039
negative regulation of developmental process GO:0051093 247 0.039
regulation of cytokine production GO:0001817 232 0.038
negative regulation of locomotion GO:0040013 118 0.038
regulation of locomotion GO:0040012 329 0.038
defense response GO:0006952 315 0.037
positive regulation of programmed cell death GO:0043068 249 0.035
cytokine production GO:0001816 247 0.035
neurological system process GO:0050877 163 0.034
multi organism cellular process GO:0044764 156 0.034
ion homeostasis GO:0050801 230 0.034
regulation of establishment of protein localization GO:0070201 242 0.034
cell adhesion GO:0007155 325 0.033
negative regulation of transport GO:0051051 176 0.033
transmembrane transport GO:0055085 399 0.033
cellular response to cytokine stimulus GO:0071345 181 0.033
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.032
secretion by cell GO:0032940 226 0.032
regulation of cell cycle process GO:0010564 266 0.032
regulation of protein localization GO:0032880 296 0.030
positive regulation of apoptotic process GO:0043065 246 0.029
cellular response to endogenous stimulus GO:0071495 336 0.029
detection of stimulus GO:0051606 85 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.029
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.029
sensory perception GO:0007600 103 0.029
interspecies interaction between organisms GO:0044419 156 0.028
peptidyl serine phosphorylation GO:0018105 101 0.028
locomotory behavior GO:0007626 1 0.028
apoptotic signaling pathway GO:0097190 268 0.028
regulation of viral process GO:0050792 103 0.028
multicellular organismal aging GO:0010259 3 0.027
negative regulation of cytokine production GO:0001818 82 0.027
lipid metabolic process GO:0006629 381 0.027
female gamete generation GO:0007292 2 0.027
mitotic cell cycle GO:0000278 326 0.026
biological adhesion GO:0022610 331 0.025
mitotic cell cycle process GO:1903047 286 0.025
positive regulation of cell death GO:0010942 263 0.025
regulation of cell activation GO:0050865 125 0.025
response to nitrogen compound GO:1901698 184 0.025
immune effector process GO:0002252 159 0.024
regulation of cytokine secretion GO:0050707 57 0.024
determination of adult lifespan GO:0008340 2 0.024
cellular response to growth factor stimulus GO:0071363 197 0.024
cytokine mediated signaling pathway GO:0019221 109 0.024
leukocyte activation GO:0045321 164 0.023
peptidyl serine modification GO:0018209 106 0.023
response to bacterium GO:0009617 144 0.023
cell activation GO:0001775 213 0.023
negative regulation of secretion by cell GO:1903531 52 0.023
defense response to other organism GO:0098542 129 0.023
oogenesis GO:0048477 2 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
neuromuscular junction development GO:0007528 3 0.022
negative regulation of cell differentiation GO:0045596 171 0.022
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
membrane organization GO:0061024 292 0.022
positive regulation of apoptotic signaling pathway GO:2001235 70 0.022
regulation of cell differentiation GO:0045595 393 0.022
negative regulation of secretion GO:0051048 58 0.022
defense response to virus GO:0051607 71 0.022
mapk cascade GO:0000165 288 0.022
entry into host GO:0044409 25 0.021
hemopoiesis GO:0030097 180 0.021
negative regulation of protein metabolic process GO:0051248 391 0.020
cytoplasmic transport GO:0016482 379 0.020
sensory perception of chemical stimulus GO:0007606 38 0.020
regulation of mapk cascade GO:0043408 262 0.020
negative regulation of multi organism process GO:0043901 92 0.020
regulation of lymphocyte activation GO:0051249 103 0.020
negative regulation of viral process GO:0048525 66 0.020
regulation of viral genome replication GO:0045069 48 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
actin filament based process GO:0030029 224 0.020
vesicle mediated transport GO:0016192 371 0.019
epithelial cell differentiation GO:0030855 141 0.019
viral life cycle GO:0019058 132 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
cellular protein catabolic process GO:0044257 261 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
cellular component morphogenesis GO:0032989 314 0.019
intracellular protein transport GO:0006886 270 0.019
ion transmembrane transport GO:0034220 338 0.019
single organism cellular localization GO:1902580 332 0.019
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
detection of stimulus involved in sensory perception GO:0050906 43 0.019
regulation of kinase activity GO:0043549 314 0.019
regulation of transferase activity GO:0051338 355 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
regulation of multi organism process GO:0043900 157 0.018
negative regulation of immune system process GO:0002683 136 0.018
cation homeostasis GO:0055080 189 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
single organism membrane organization GO:0044802 268 0.017
response to growth factor GO:0070848 205 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
inorganic cation transmembrane transport GO:0098662 194 0.017
chemical homeostasis GO:0048878 306 0.017
cation transport GO:0006812 331 0.017
negative regulation of interleukin 13 production GO:0032696 3 0.017
viral genome replication GO:0019079 50 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
regulation of immune response GO:0050776 201 0.017
regeneration GO:0031099 4 0.017
protein localization to organelle GO:0033365 280 0.017
memory GO:0007613 3 0.017
regulation of cellular component movement GO:0051270 334 0.017
type i interferon signaling pathway GO:0060337 11 0.017
positive regulation of cell cycle GO:0045787 140 0.017
cell division GO:0051301 168 0.017
natural killer cell activation GO:0030101 12 0.017
immune system development GO:0002520 195 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
response to abiotic stimulus GO:0009628 336 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
defense response to bacterium GO:0042742 63 0.016
negative regulation of cell cycle GO:0045786 193 0.016
lymphocyte activation GO:0046649 133 0.016
muscle system process GO:0003012 81 0.016
regulation of t cell activation GO:0050863 77 0.016
regulation of immune effector process GO:0002697 91 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
positive regulation of transport GO:0051050 336 0.016
nuclear transport GO:0051169 179 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
nucleotide catabolic process GO:0009166 408 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
peptidyl tyrosine modification GO:0018212 170 0.016
organic hydroxy compound metabolic process GO:1901615 147 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
purine containing compound catabolic process GO:0072523 411 0.016
regulation of proteolysis GO:0030162 293 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
regulation of protein secretion GO:0050708 86 0.016
cell cycle phase transition GO:0044770 173 0.016
regulation of cell division GO:0051302 116 0.016
positive regulation of cell cycle process GO:0090068 106 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
regulation of cell adhesion GO:0030155 166 0.015
detection of chemical stimulus GO:0009593 55 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
regulation of leukocyte mediated immunity GO:0002703 38 0.015
positive regulation of aldosterone metabolic process GO:0032346 2 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
cellular homeostasis GO:0019725 196 0.015
rhythmic behavior GO:0007622 2 0.015
regulation of system process GO:0044057 101 0.015
regulation of growth GO:0040008 165 0.015
lymphocyte mediated immunity GO:0002449 48 0.015
regulation of peptidyl serine phosphorylation GO:0033135 50 0.015
positive regulation of developmental process GO:0051094 314 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
cell morphogenesis GO:0000902 296 0.015
sensory perception of smell GO:0007608 2 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.015
sensory perception of taste GO:0050909 36 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
regulation of protein kinase activity GO:0045859 289 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
leukocyte mediated immunity GO:0002443 59 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
chromatin organization GO:0006325 351 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
protein ubiquitination GO:0016567 314 0.014
protein secretion GO:0009306 98 0.014
organophosphate catabolic process GO:0046434 430 0.014
angiogenesis GO:0001525 147 0.014
regulation of cellular response to stress GO:0080135 244 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
entry into other organism involved in symbiotic interaction GO:0051828 25 0.014
nitrogen compound transport GO:0071705 191 0.014
protein targeting GO:0006605 187 0.014
nervous system development GO:0007399 293 0.014
dna repair GO:0006281 198 0.014
cell growth GO:0016049 160 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
negative regulation of cell death GO:0060548 345 0.014
jak stat cascade GO:0007259 46 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
cellular organohalogen metabolic process GO:0090345 2 0.013
protein catabolic process GO:0030163 325 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
chromatin modification GO:0016568 298 0.013
regulation of dna metabolic process GO:0051052 153 0.013
actin mediated cell contraction GO:0070252 12 0.013
cation transmembrane transport GO:0098655 238 0.013
blood vessel morphogenesis GO:0048514 162 0.013
spermatid differentiation GO:0048515 4 0.013
multicellular organismal signaling GO:0035637 34 0.013
t cell activation GO:0042110 99 0.013
protein import GO:0017038 130 0.013
negative regulation of organelle organization GO:0010639 126 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
cytokine secretion GO:0050663 64 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
cell projection organization GO:0030030 252 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.013
regulation of membrane potential GO:0042391 95 0.013
nucleoside triphosphate metabolic process GO:0009141 422 0.013
peripheral nervous system development GO:0007422 2 0.013
small molecule biosynthetic process GO:0044283 157 0.013
response to transforming growth factor beta GO:0071559 94 0.013
nucleoside catabolic process GO:0009164 408 0.013
negative regulation of leukocyte differentiation GO:1902106 24 0.013
cellular lipid metabolic process GO:0044255 303 0.013
interaction with host GO:0051701 42 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
cellular cation homeostasis GO:0030003 163 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
movement in host environment GO:0052126 25 0.012
regulation of cell motility GO:2000145 299 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
protein oligomerization GO:0051259 173 0.012
endomembrane system organization GO:0010256 196 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
regulation of cell migration GO:0030334 289 0.012
organelle fission GO:0048285 149 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.012
negative regulation of protein secretion GO:0050709 29 0.012
negative regulation of cytokine secretion GO:0050710 20 0.012
oocyte differentiation GO:0009994 2 0.012
cellular ion homeostasis GO:0006873 168 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
covalent chromatin modification GO:0016569 254 0.012
response to dsrna GO:0043331 25 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
regulation of interleukin 5 production GO:0032674 6 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
regulation of jak stat cascade GO:0046425 44 0.012
adaptive immune response GO:0002250 49 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
regulation of protein catabolic process GO:0042176 155 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
oocyte development GO:0048599 1 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
regulation of cell growth GO:0001558 135 0.012
single organism cell adhesion GO:0098602 179 0.012
ras protein signal transduction GO:0007265 73 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
blood circulation GO:0008015 113 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
regulation of binding GO:0051098 111 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
striated muscle contraction GO:0006941 52 0.012
carbohydrate metabolic process GO:0005975 207 0.012
positive regulation of secretion by cell GO:1903532 108 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.011
metal ion homeostasis GO:0055065 169 0.011
negative regulation of protein modification process GO:0031400 200 0.011
entry into host cell GO:0030260 25 0.011
epithelium development GO:0060429 227 0.011
blastoderm segmentation GO:0007350 2 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
positive regulation of organelle organization GO:0010638 195 0.011
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
regulation of epithelial cell migration GO:0010632 93 0.011
organelle assembly GO:0070925 176 0.011
positive regulation of kinase activity GO:0033674 204 0.011
regulation of leukocyte activation GO:0002694 115 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
positive regulation of cytokine production GO:0001819 167 0.011
gamma aminobutyric acid signaling pathway GO:0007214 3 0.011
mitotic nuclear division GO:0007067 119 0.011
tyrosine phosphorylation of stat protein GO:0007260 33 0.011
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
viral entry into host cell GO:0046718 24 0.011
adult locomotory behavior GO:0008344 1 0.011
growth GO:0040007 202 0.011
leukocyte differentiation GO:0002521 98 0.011
negative regulation of transferase activity GO:0051348 124 0.011
cell projection assembly GO:0030031 126 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
associative learning GO:0008306 1 0.011
protein localization to nucleus GO:0034504 136 0.011
steroid metabolic process GO:0008202 94 0.011
epithelial cell proliferation GO:0050673 128 0.011
negative regulation of programmed cell death GO:0043069 321 0.010
maintenance of location GO:0051235 112 0.010
stem cell division GO:0017145 2 0.010
cell part morphogenesis GO:0032990 137 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
regulation of leukocyte differentiation GO:1902105 61 0.010
sulfur compound metabolic process GO:0006790 101 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
tripartite regional subdivision GO:0007351 2 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010
nuclear division GO:0000280 128 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
positive regulation of catabolic process GO:0009896 310 0.010
cytokinesis GO:0000910 96 0.010
demethylation GO:0070988 37 0.010
protein modification by small protein conjugation GO:0032446 342 0.010
regulation of intracellular transport GO:0032386 195 0.010
response to radiation GO:0009314 151 0.010
guanosine containing compound metabolic process GO:1901068 244 0.010
circadian behavior GO:0048512 2 0.010
actin filament based movement GO:0030048 17 0.010
fatty acid metabolic process GO:0006631 115 0.010
positive regulation of secretion GO:0051047 116 0.010

IFNA4 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.022
eye and adnexa disease DOID:1492 150 0.022
nervous system disease DOID:863 431 0.022
eye disease DOID:5614 149 0.022
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
central nervous system disease DOID:331 186 0.021
organ system cancer DOID:0050686 164 0.019
disease of metabolism DOID:0014667 295 0.019
retinal disease DOID:5679 118 0.017
retinal degeneration DOID:8466 89 0.013
immune system disease DOID:2914 155 0.011
disease of mental health DOID:150 70 0.011
musculoskeletal system disease DOID:17 223 0.011