Homo sapiens

0 known processes

ZNF708

zinc finger protein 708

(Aliases: DKFZp686L10267,KOX8,ZNF15,FLJ16755,FLJ46310,ZNF15L1)

ZNF708 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of interleukin 1 mediated signaling pathway GO:2000659 3 0.984
Human
negative regulation of interleukin 1 mediated signaling pathway GO:2000660 2 0.798
Human
negative regulation of jun kinase activity GO:0043508 4 0.636
Human
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.620
Human
cellular response to interleukin 1 GO:0071347 35 0.419
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.416
Human
regulation of myeloid cell differentiation GO:0045637 81 0.396
Human
regulation of mapk cascade GO:0043408 262 0.369
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.346
Human
negative regulation of myeloid cell differentiation GO:0045638 42 0.318
Human
mapk cascade GO:0000165 288 0.317
Human
negative regulation of myeloid leukocyte differentiation GO:0002762 16 0.314
Human
negative regulation of multicellular organismal process GO:0051241 317 0.303
Human
negative regulation of protein phosphorylation GO:0001933 140 0.302
Human
response to cytokine GO:0034097 232 0.296
Human
interleukin 1 mediated signaling pathway GO:0070498 12 0.290
Human
midbrain development GO:0030901 45 0.282
Human
regulation of myeloid leukocyte differentiation GO:0002761 39 0.276
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.272
Human
regulation of transcription regulatory region dna binding GO:2000677 15 0.255
Human
regulation of tumor necrosis factor mediated signaling pathway GO:0010803 12 0.253
Human
regulation of cell differentiation GO:0045595 393 0.247
Human
jnk cascade GO:0007254 80 0.240
Human
myeloid cell differentiation GO:0030099 117 0.239
Human
regulation of jnk cascade GO:0046328 73 0.235
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.231
Human
cellular response to cytokine stimulus GO:0071345 181 0.231
Human
appendage morphogenesis GO:0035107 16 0.230
Human
regulation of transferase activity GO:0051338 355 0.230
Human
negative regulation of response to cytokine stimulus GO:0060761 25 0.224
Human
hemopoiesis GO:0030097 180 0.224
Human
regulation of kinase activity GO:0043549 314 0.222
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.217
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.214
Human
negative regulation of protein metabolic process GO:0051248 391 0.203
Human
osteoclast differentiation GO:0030316 21 0.203
Human
immune system development GO:0002520 195 0.199
Human
signal transduction by phosphorylation GO:0023014 297 0.198
Human
response to tumor necrosis factor GO:0034612 76 0.193
Human
regulation of leukocyte differentiation GO:1902105 61 0.191
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.187
Human
regulation of map kinase activity GO:0043405 108 0.187
Human
negative regulation of jnk cascade GO:0046329 16 0.183
Human
stress activated mapk cascade GO:0051403 93 0.183
Human
cellular response to tumor necrosis factor GO:0071356 63 0.183
Human
regulation of protein kinase activity GO:0045859 289 0.177
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.171
Human
regulation of stress activated mapk cascade GO:0032872 84 0.166
Human
cytokine mediated signaling pathway GO:0019221 109 0.163
Human
i kappab kinase nf kappab signaling GO:0007249 166 0.158
Human
regulation of binding GO:0051098 111 0.155
Human
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.151
Human
negative regulation of developmental process GO:0051093 247 0.149
Human
regulation of dna binding GO:0051101 37 0.148
Human
response to interleukin 1 GO:0070555 47 0.147
Human
negative regulation of tumor necrosis factor mediated signaling pathway GO:0010804 7 0.141
Human
regulation of cytokine mediated signaling pathway GO:0001959 41 0.138
Human
negative regulation of immune system process GO:0002683 136 0.136
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.135
Human
substantia nigra development GO:0021762 45 0.129
Human
negative regulation of leukocyte differentiation GO:1902106 24 0.127
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.126
Human
neural nucleus development GO:0048857 47 0.126
Human
negative regulation of dna binding GO:0043392 18 0.125
Human
negative regulation of catalytic activity GO:0043086 335 0.120
Human
myeloid leukocyte differentiation GO:0002573 60 0.118
Human
regulation of cellular response to stress GO:0080135 244 0.115
Human
appendage development GO:0048736 23 0.111
Human
leukocyte differentiation GO:0002521 98 0.107
Human
regulation of osteoclast differentiation GO:0045670 18 0.107
Human
negative regulation of binding GO:0051100 57 0.097
Human
negative regulation of stress activated mapk cascade GO:0032873 19 0.097
Human
negative regulation of transferase activity GO:0051348 124 0.096
Human
negative regulation of protein modification process GO:0031400 200 0.095
Human
negative regulation of phosphorylation GO:0042326 174 0.094
Human
limb morphogenesis GO:0035108 16 0.090
Human
regulation of response to cytokine stimulus GO:0060759 46 0.088
Human
negative regulation of osteoclast differentiation GO:0045671 8 0.085
Human
regulation of jun kinase activity GO:0043506 27 0.084
Human
negative regulation of kinase activity GO:0033673 106 0.084
Human
brain development GO:0007420 97 0.080
Human
nervous system development GO:0007399 293 0.071
Human
positive regulation of transcription from rna polymerase ii promoter during mitosis GO:0046022 1 0.070
negative regulation of intracellular signal transduction GO:1902532 183 0.066
Human
negative regulation of protein kinase activity GO:0006469 98 0.064
Human
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.062
Human
head development GO:0060322 108 0.062
Human
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.061
Human
tumor necrosis factor mediated signaling pathway GO:0033209 27 0.053
Human
central nervous system development GO:0007417 123 0.053
Human
negative regulation of mapk cascade GO:0043409 56 0.049
Human
negative regulation of cell differentiation GO:0045596 171 0.048
Human
determination of adult lifespan GO:0008340 2 0.042
negative regulation of map kinase activity GO:0043407 27 0.042
Human
positive regulation of transcription during mitosis GO:0045897 2 0.041
post embryonic development GO:0009791 2 0.040
limb development GO:0060173 23 0.038
Human
cellular amino acid metabolic process GO:0006520 116 0.035
amine metabolic process GO:0009308 44 0.035
regulation of transcription during mitosis GO:0045896 2 0.034
multicellular organismal aging GO:0010259 3 0.031
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.030
cellular ketone metabolic process GO:0042180 80 0.030
cellular amine metabolic process GO:0044106 41 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
positive regulation of phosphorylation GO:0042327 394 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
regulation of cellular ketone metabolic process GO:0010565 50 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
locomotory behavior GO:0007626 1 0.026
female gamete generation GO:0007292 2 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
mitotic cell cycle GO:0000278 326 0.024
organophosphate catabolic process GO:0046434 430 0.024
segmentation GO:0035282 4 0.024
protein catabolic process GO:0030163 325 0.024
purine containing compound catabolic process GO:0072523 411 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.022
cytoplasmic transport GO:0016482 379 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
positive regulation of programmed cell death GO:0043068 249 0.021
cell morphogenesis GO:0000902 296 0.021
neuromuscular junction development GO:0007528 3 0.021
single organism cellular localization GO:1902580 332 0.021
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
negative regulation of cell death GO:0060548 345 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
regulation of cell cycle process GO:0010564 266 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
intracellular protein transport GO:0006886 270 0.020
regulation of cell cycle GO:0051726 393 0.019
chemical homeostasis GO:0048878 306 0.019
positive regulation of cell death GO:0010942 263 0.019
nucleotide catabolic process GO:0009166 408 0.019
ras protein signal transduction GO:0007265 73 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
positive regulation of cell proliferation GO:0008284 301 0.019
immune response GO:0006955 307 0.019
mitotic cell cycle process GO:1903047 286 0.019
oogenesis GO:0048477 2 0.019
ribonucleotide catabolic process GO:0009261 405 0.019
purine nucleotide catabolic process GO:0006195 405 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
nucleoside triphosphate catabolic process GO:0009143 394 0.018
maintenance of location GO:0051235 112 0.017
cellular component morphogenesis GO:0032989 314 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
negative regulation of transcription regulatory region dna binding GO:2000678 6 0.017
Human
posttranscriptional regulation of gene expression GO:0010608 213 0.017
response to oxygen containing compound GO:1901700 369 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
protein localization to organelle GO:0033365 280 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
positive regulation of catabolic process GO:0009896 310 0.016
nuclear transport GO:0051169 179 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
negative regulation of programmed cell death GO:0043069 321 0.016
regulation of protein localization GO:0032880 296 0.016
chromatin organization GO:0006325 351 0.016
positive regulation of transport GO:0051050 336 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
anterior posterior axis specification GO:0009948 2 0.015
blastoderm segmentation GO:0007350 2 0.015
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.015
regulation of cellular component movement GO:0051270 334 0.015
translation GO:0006412 132 0.015
response to abiotic stimulus GO:0009628 336 0.015
spermatid development GO:0007286 4 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
biological adhesion GO:0022610 331 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
positive regulation of synaptic transmission GO:0050806 4 0.014
mrna metabolic process GO:0016071 175 0.014
nucleoside catabolic process GO:0009164 408 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
cellular homeostasis GO:0019725 196 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
actin filament based process GO:0030029 224 0.014
positive regulation of transferase activity GO:0051347 227 0.014
defense response GO:0006952 315 0.014
spermatid differentiation GO:0048515 4 0.014
innate immune response GO:0045087 178 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
cellular protein complex assembly GO:0043623 188 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
regulation of proteolysis GO:0030162 293 0.014
apoptotic signaling pathway GO:0097190 268 0.014
rna interference GO:0016246 4 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
chromatin modification GO:0016568 298 0.014
system process GO:0003008 349 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
transmembrane transport GO:0055085 399 0.014
carbohydrate metabolic process GO:0005975 207 0.013
positive regulation of immune system process GO:0002684 283 0.013
protein ubiquitination GO:0016567 314 0.013
rho protein signal transduction GO:0007266 26 0.013
regeneration GO:0031099 4 0.013
memory GO:0007613 3 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
membrane organization GO:0061024 292 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
adult locomotory behavior GO:0008344 1 0.013
cell cycle phase transition GO:0044770 173 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
protein modification by small protein removal GO:0070646 92 0.013
regulation of cell motility GO:2000145 299 0.013
positive regulation of kinase activity GO:0033674 204 0.013
protein processing GO:0016485 226 0.013
protein maturation GO:0051604 233 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
dephosphorylation GO:0016311 209 0.012
regulation of intracellular transport GO:0032386 195 0.012
mitotic nuclear division GO:0007067 119 0.012
cytokine production GO:0001816 247 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
organelle fission GO:0048285 149 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
regulation of cell migration GO:0030334 289 0.012
sex determination GO:0007530 3 0.012
cell projection organization GO:0030030 252 0.012
regulation of cytokine production GO:0001817 232 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
protein acylation GO:0043543 138 0.012
lung alveolus development GO:0048286 4 0.012
secretion by cell GO:0032940 226 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
protein oligomerization GO:0051259 173 0.012
tripartite regional subdivision GO:0007351 2 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
actin cytoskeleton organization GO:0030036 207 0.012
rna processing GO:0006396 255 0.012
organelle assembly GO:0070925 176 0.012
cell adhesion GO:0007155 325 0.012
oocyte development GO:0048599 1 0.012
organ formation GO:0048645 3 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
single organism membrane organization GO:0044802 268 0.012
regulation of locomotion GO:0040012 329 0.012
metal ion transport GO:0030001 272 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
endomembrane system organization GO:0010256 196 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
response to external biotic stimulus GO:0043207 261 0.012
ion homeostasis GO:0050801 230 0.012
negative regulation of cell cycle GO:0045786 193 0.012
positive regulation of organelle organization GO:0010638 195 0.012
positive regulation of developmental process GO:0051094 314 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
protein targeting GO:0006605 187 0.011
hindbrain development GO:0030902 3 0.011
peripheral nervous system development GO:0007422 2 0.011
regulation of protein processing GO:0070613 150 0.011
regulation of protein transport GO:0051223 213 0.011
positive regulation of cell migration GO:0030335 172 0.011
regulation of protein catabolic process GO:0042176 155 0.011
rhythmic behavior GO:0007622 2 0.011
atp metabolic process GO:0046034 176 0.011
mating GO:0007618 1 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
cation transport GO:0006812 331 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
regulation of secretion GO:0051046 194 0.011
salivary gland morphogenesis GO:0007435 4 0.011
lipid metabolic process GO:0006629 381 0.011
inner ear morphogenesis GO:0042472 4 0.011
nitrogen compound transport GO:0071705 191 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
protein localization to nucleus GO:0034504 136 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
microtubule based process GO:0007017 210 0.011
rna splicing GO:0008380 131 0.011
cellular protein catabolic process GO:0044257 261 0.011
stem cell division GO:0017145 2 0.011
nerve development GO:0021675 4 0.011
cell growth GO:0016049 160 0.011
cellular chemical homeostasis GO:0055082 180 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
response to biotic stimulus GO:0009607 276 0.011
growth GO:0040007 202 0.011
vesicle mediated transport GO:0016192 371 0.011
interspecies interaction between organisms GO:0044419 156 0.011
regulation of secretion by cell GO:1903530 177 0.011
ion transmembrane transport GO:0034220 338 0.011
cell fate determination GO:0001709 3 0.011
response to lipid GO:0033993 206 0.011
response to fungus GO:0009620 4 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
sequestering of metal ion GO:0051238 24 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
actin filament based movement GO:0030048 17 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
circadian behavior GO:0048512 2 0.010
motor neuron axon guidance GO:0008045 2 0.010
cellular lipid metabolic process GO:0044255 303 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
regulation of protein complex assembly GO:0043254 147 0.010
positive regulation of cell motility GO:2000147 177 0.010
oocyte differentiation GO:0009994 2 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
response to other organism GO:0051707 261 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
tissue regeneration GO:0042246 3 0.010
negative regulation of transport GO:0051051 176 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
histone modification GO:0016570 251 0.010
regulation of protein maturation GO:1903317 150 0.010
compound eye development GO:0048749 1 0.010
negative regulation of protein maturation GO:1903318 142 0.010
multi organism cellular process GO:0044764 156 0.010

ZNF708 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.026
sensory system disease DOID:0050155 203 0.024
nervous system disease DOID:863 431 0.024
eye and adnexa disease DOID:1492 150 0.019
eye disease DOID:5614 149 0.019
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
central nervous system disease DOID:331 186 0.018
musculoskeletal system disease DOID:17 223 0.015
inherited metabolic disorder DOID:655 242 0.015
organ system cancer DOID:0050686 164 0.015
connective tissue disease DOID:65 109 0.012
retinal disease DOID:5679 118 0.011
immune system disease DOID:2914 155 0.011
bone disease DOID:0080001 88 0.010