Homo sapiens

30 known processes

PCNP

PEST proteolytic signal containing nuclear protein

(Aliases: DKFZp781I24156)

PCNP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.244
regulation of cellular amino acid metabolic process GO:0006521 6 0.243
cellular macromolecular complex assembly GO:0034622 324 0.182
neurotransmitter secretion GO:0007269 4 0.181
negative regulation of cell death GO:0060548 345 0.172
regulation of cellular amine metabolic process GO:0033238 11 0.110
positive regulation of transferase activity GO:0051347 227 0.084
regulation of cell differentiation GO:0045595 393 0.082
memory GO:0007613 3 0.075
response to nitrogen compound GO:1901698 184 0.072
single organism cellular localization GO:1902580 332 0.068
neuromuscular junction development GO:0007528 3 0.067
cellular response to oxygen containing compound GO:1901701 276 0.066
cellular amine metabolic process GO:0044106 41 0.066
mapk cascade GO:0000165 288 0.064
cellular amino acid metabolic process GO:0006520 116 0.063
regulation of cell projection organization GO:0031344 107 0.063
cell morphogenesis GO:0000902 296 0.062
single organism membrane organization GO:0044802 268 0.062
protein localization to membrane GO:0072657 160 0.060
regulation of kinase activity GO:0043549 314 0.060
oocyte development GO:0048599 1 0.059
signal transduction by phosphorylation GO:0023014 297 0.059
amine metabolic process GO:0009308 44 0.059
cellular component morphogenesis GO:0032989 314 0.057
regulation of protein kinase activity GO:0045859 289 0.056
purine ribonucleoside metabolic process GO:0046128 437 0.054
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.052
regulation of cellular response to stress GO:0080135 244 0.052
cilium assembly GO:0042384 63 0.052
organelle fission GO:0048285 149 0.050
ribonucleoprotein complex biogenesis GO:0022613 116 0.050
positive regulation of kinase activity GO:0033674 204 0.050
negative regulation of phosphate metabolic process GO:0045936 267 0.049
negative regulation of cellular amine metabolic process GO:0033239 3 0.049
oocyte differentiation GO:0009994 2 0.048
carbohydrate metabolic process GO:0005975 207 0.048
positive regulation of protein phosphorylation GO:0001934 313 0.048
cellular ketone metabolic process GO:0042180 80 0.047
determination of adult lifespan GO:0008340 2 0.047
positive regulation of phosphorylation GO:0042327 394 0.046
membrane organization GO:0061024 292 0.045
negative regulation of phosphorus metabolic process GO:0010563 267 0.045
secretion GO:0046903 254 0.044
single organism carbohydrate metabolic process GO:0044723 193 0.043
positive regulation of cellular amine metabolic process GO:0033240 7 0.043
positive regulation of protein kinase activity GO:0045860 190 0.041
cytoplasmic transport GO:0016482 379 0.040
signal release GO:0023061 70 0.039
enzyme linked receptor protein signaling pathway GO:0007167 303 0.039
mitotic cell cycle GO:0000278 326 0.039
regulation of neural precursor cell proliferation GO:2000177 4 0.039
nitrogen compound transport GO:0071705 191 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.038
negative regulation of phosphorylation GO:0042326 174 0.038
negative regulation of cellular component organization GO:0051129 235 0.038
tissue migration GO:0090130 119 0.037
nuclear division GO:0000280 128 0.037
positive regulation of catabolic process GO:0009896 310 0.037
ribonucleoprotein complex assembly GO:0022618 78 0.036
cellular response to endogenous stimulus GO:0071495 336 0.036
negative regulation of cell differentiation GO:0045596 171 0.035
stress activated mapk cascade GO:0051403 93 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
anterior posterior axis specification GO:0009948 2 0.035
mrna splicing via spliceosome GO:0000398 89 0.035
cell development GO:0048468 328 0.034
long term memory GO:0007616 2 0.034
mitotic cell cycle process GO:1903047 286 0.034
cell division GO:0051301 168 0.034
organelle assembly GO:0070925 176 0.033
nervous system development GO:0007399 293 0.033
cell projection organization GO:0030030 252 0.032
prostate gland development GO:0030850 3 0.032
positive regulation of immune system process GO:0002684 283 0.032
system process GO:0003008 349 0.032
epithelium development GO:0060429 227 0.032
negative regulation of intracellular signal transduction GO:1902532 183 0.031
regulation of locomotion GO:0040012 329 0.031
regulation of mapk cascade GO:0043408 262 0.030
chemical homeostasis GO:0048878 306 0.030
regulation of mitotic cell cycle GO:0007346 189 0.030
response to abiotic stimulus GO:0009628 336 0.029
response to hormone GO:0009725 175 0.029
rna processing GO:0006396 255 0.028
positive regulation of meiotic cell cycle GO:0051446 2 0.027
response to organic cyclic compound GO:0014070 204 0.027
negative regulation of programmed cell death GO:0043069 321 0.027
cell part morphogenesis GO:0032990 137 0.027
neuron development GO:0048666 113 0.027
regulation of cellular component movement GO:0051270 334 0.027
mrna processing GO:0006397 133 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.027
negative regulation of multicellular organismal process GO:0051241 317 0.026
regulation of transferase activity GO:0051338 355 0.026
epithelium migration GO:0090132 119 0.025
mrna metabolic process GO:0016071 175 0.025
small molecule biosynthetic process GO:0044283 157 0.025
cell cell signaling GO:0007267 155 0.024
regulation of nuclear division GO:0051783 65 0.024
regulation of cellular component size GO:0032535 82 0.024
posttranscriptional regulation of gene expression GO:0010608 213 0.024
segmentation GO:0035282 4 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
negative regulation of developmental process GO:0051093 247 0.023
epithelial cell migration GO:0010631 119 0.023
response to other organism GO:0051707 261 0.023
regulation of cell migration GO:0030334 289 0.023
behavioral response to ethanol GO:0048149 2 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
circadian behavior GO:0048512 2 0.022
cellular response to nitrogen compound GO:1901699 144 0.022
reproductive process GO:0022414 106 0.022
mitotic nuclear division GO:0007067 119 0.022
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
response to organonitrogen compound GO:0010243 156 0.021
negative regulation of synaptic transmission GO:0050805 2 0.021
meiosis i GO:0007127 4 0.021
cell activation GO:0001775 213 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
regulation of cell cycle process GO:0010564 266 0.020
cell projection morphogenesis GO:0048858 129 0.020
negative regulation of cellular component movement GO:0051271 106 0.020
apoptotic signaling pathway GO:0097190 268 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
response to peptide GO:1901652 65 0.020
regulation of growth GO:0040008 165 0.020
cell cycle phase transition GO:0044770 173 0.020
secretion by cell GO:0032940 226 0.020
regulation of cell cycle GO:0051726 393 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
immune response GO:0006955 307 0.019
negative regulation of growth GO:0045926 97 0.019
somitogenesis GO:0001756 2 0.019
monosaccharide metabolic process GO:0005996 74 0.019
response to fungus GO:0009620 4 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
associative learning GO:0008306 1 0.019
regulation of neurotransmitter levels GO:0001505 15 0.018
cellular homeostasis GO:0019725 196 0.018
spermatid differentiation GO:0048515 4 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
cellular lipid metabolic process GO:0044255 303 0.018
regulation of cell division GO:0051302 116 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
neuroblast proliferation GO:0007405 4 0.018
protein localization to plasma membrane GO:0072659 93 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
maintenance of location GO:0051235 112 0.018
dephosphorylation GO:0016311 209 0.017
response to radiation GO:0009314 151 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.017
cilium morphogenesis GO:0060271 75 0.017
regulation of carbohydrate metabolic process GO:0006109 54 0.017
plasma membrane organization GO:0007009 115 0.017
stem cell differentiation GO:0048863 93 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
positive regulation of developmental process GO:0051094 314 0.017
small gtpase mediated signal transduction GO:0007264 78 0.016
regulation of translation GO:0006417 89 0.016
multicellular organismal aging GO:0010259 3 0.016
cerebellum development GO:0021549 2 0.016
microtubule based process GO:0007017 210 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
regulation of meiotic cell cycle GO:0051445 4 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
female gamete generation GO:0007292 2 0.016
protein localization to organelle GO:0033365 280 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
stress activated protein kinase signaling cascade GO:0031098 94 0.016
negative regulation of cell development GO:0010721 48 0.016
cell projection assembly GO:0030031 126 0.015
oogenesis GO:0048477 2 0.015
convergent extension GO:0060026 1 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.015
ras protein signal transduction GO:0007265 73 0.015
peptide transport GO:0015833 74 0.015
protein targeting GO:0006605 187 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
positive regulation of protein catabolic process GO:0045732 75 0.015
stem cell division GO:0017145 2 0.015
regulation of neuron projection development GO:0010975 57 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
regulation of anatomical structure size GO:0090066 101 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
endocytosis GO:0006897 159 0.014
organic acid biosynthetic process GO:0016053 97 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
neurological system process GO:0050877 163 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
metal ion transport GO:0030001 272 0.014
actin filament based process GO:0030029 224 0.014
regulation of mrna metabolic process GO:1903311 53 0.014
positive regulation of locomotion GO:0040017 186 0.014
regulation of cell motility GO:2000145 299 0.014
generation of neurons GO:0048699 152 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
protein catabolic process GO:0030163 325 0.014
rna interference GO:0016246 4 0.014
nucleotide catabolic process GO:0009166 408 0.014
cellular response to peptide GO:1901653 59 0.014
sensory perception GO:0007600 103 0.014
hexose metabolic process GO:0019318 55 0.014
response to oxygen containing compound GO:1901700 369 0.014
positive regulation of cell death GO:0010942 263 0.014
regulation of cell development GO:0060284 161 0.014
positive regulation of neural precursor cell proliferation GO:2000179 2 0.014
purine containing compound catabolic process GO:0072523 411 0.014
spermatid development GO:0007286 4 0.014
cytokine production GO:0001816 247 0.014
negative regulation of cell growth GO:0030308 83 0.014
positive regulation of programmed cell death GO:0043068 249 0.013
lipoprotein metabolic process GO:0042157 42 0.013
response to virus GO:0009615 126 0.013
response to oxidative stress GO:0006979 121 0.013
carbohydrate biosynthetic process GO:0016051 42 0.013
gland development GO:0048732 48 0.013
cellular protein complex assembly GO:0043623 188 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
vesicle mediated transport GO:0016192 371 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.013
translation GO:0006412 132 0.013
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of cell activation GO:0050865 125 0.013
leukocyte activation GO:0045321 164 0.013
regulation of metal ion transport GO:0010959 120 0.013
cell adhesion GO:0007155 325 0.013
negative regulation of lipid metabolic process GO:0045833 38 0.013
cellular chemical homeostasis GO:0055082 180 0.012
positive regulation of cell migration GO:0030335 172 0.012
skeletal system development GO:0001501 79 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
mating GO:0007618 1 0.012
ribonucleoprotein complex subunit organization GO:0071826 81 0.012
tube closure GO:0060606 3 0.012
neuron differentiation GO:0030182 138 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
nuclear transport GO:0051169 179 0.012
negative regulation of protein metabolic process GO:0051248 391 0.012
regulation of leukocyte activation GO:0002694 115 0.012
cell type specific apoptotic process GO:0097285 125 0.012
chromatin modification GO:0016568 298 0.012
cell cycle g1 s phase transition GO:0044843 80 0.012
negative regulation of mapk cascade GO:0043409 56 0.012
negative regulation of transferase activity GO:0051348 124 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
lipid localization GO:0010876 106 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
regulation of stress activated mapk cascade GO:0032872 84 0.011
regulation of system process GO:0044057 101 0.011
locomotory behavior GO:0007626 1 0.011
regulation of chromosome organization GO:0033044 103 0.011
head development GO:0060322 108 0.011
sequestering of calcium ion GO:0051208 17 0.011
positive regulation of proteolysis GO:0045862 142 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
connective tissue development GO:0061448 39 0.011
g1 s transition of mitotic cell cycle GO:0000082 78 0.011
regulation of meiosis GO:0040020 3 0.011
natural killer cell differentiation GO:0001779 2 0.011
intracellular protein transport GO:0006886 270 0.011
negative regulation of axonogenesis GO:0050771 4 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
rna splicing via transesterification reactions GO:0000375 90 0.011
tissue morphogenesis GO:0048729 96 0.011
rho protein signal transduction GO:0007266 26 0.011
regulation of secretion GO:0051046 194 0.011
chemotaxis GO:0006935 157 0.011
stem cell development GO:0048864 69 0.011
protein kinase b signaling GO:0043491 69 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
negative regulation of organelle organization GO:0010639 126 0.011
transmembrane transport GO:0055085 399 0.011
cellular response to lipid GO:0071396 127 0.011
regulation of jnk cascade GO:0046328 73 0.011
establishment of rna localization GO:0051236 39 0.011
organophosphate catabolic process GO:0046434 430 0.011
regulation of t cell activation GO:0050863 77 0.011
behavior GO:0007610 112 0.011
positive regulation of leukocyte activation GO:0002696 80 0.011
central nervous system development GO:0007417 123 0.011
neurogenesis GO:0022008 169 0.011
negative regulation of locomotion GO:0040013 118 0.011
epidermal growth factor receptor signaling pathway GO:0007173 39 0.011
organelle localization GO:0051640 84 0.010
response to peptide hormone GO:0043434 61 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
positive regulation of epithelial cell migration GO:0010634 55 0.010
cellular calcium ion homeostasis GO:0006874 117 0.010
glycosyl compound catabolic process GO:1901658 413 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.010
sleep GO:0030431 2 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
regulation of cell adhesion GO:0030155 166 0.010
multi organism cellular process GO:0044764 156 0.010
erbb signaling pathway GO:0038127 44 0.010
protein autophosphorylation GO:0046777 123 0.010
response to insulin GO:0032868 45 0.010
biological adhesion GO:0022610 331 0.010
growth GO:0040007 202 0.010
ameboidal type cell migration GO:0001667 135 0.010
positive regulation of cellular protein catabolic process GO:1903364 37 0.010
chromosome segregation GO:0007059 114 0.010
lipoprotein biosynthetic process GO:0042158 33 0.010

PCNP disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.026
central nervous system disease DOID:331 186 0.018
nervous system disease DOID:863 431 0.018
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
neurodegenerative disease DOID:1289 102 0.012