Homo sapiens

101 known processes

NDUFS4

NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

(Aliases: AQDQ,CI-18)

NDUFS4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleoside metabolic process GO:0046128 437 0.370
ribonucleoside monophosphate metabolic process GO:0009161 187 0.317
nucleoside monophosphate metabolic process GO:0009123 191 0.305
ribonucleoside triphosphate metabolic process GO:0009199 412 0.298
multicellular organismal aging GO:0010259 3 0.291
purine nucleoside monophosphate metabolic process GO:0009126 186 0.291
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.289
nucleoside triphosphate metabolic process GO:0009141 422 0.217
determination of adult lifespan GO:0008340 2 0.206
purine nucleoside triphosphate metabolic process GO:0009144 412 0.193
regulation of neural precursor cell proliferation GO:2000177 4 0.179
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.170
atp metabolic process GO:0046034 176 0.145
post embryonic development GO:0009791 2 0.128
Worm
atp catabolic process GO:0006200 157 0.109
neuroblast proliferation GO:0007405 4 0.102
ribonucleoside catabolic process GO:0042454 406 0.102
purine ribonucleoside catabolic process GO:0046130 398 0.095
purine nucleotide biosynthetic process GO:0006164 84 0.090
purine nucleoside monophosphate catabolic process GO:0009128 158 0.085
nervous system development GO:0007399 293 0.084
mitochondrial respiratory chain complex assembly GO:0033108 23 0.084
oogenesis GO:0048477 2 0.079
purine nucleoside triphosphate catabolic process GO:0009146 392 0.079
cation transmembrane transport GO:0098655 238 0.077
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.076
organonitrogen compound biosynthetic process GO:1901566 200 0.076
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.076
organophosphate biosynthetic process GO:0090407 163 0.074
energy derivation by oxidation of organic compounds GO:0015980 43 0.073
female gamete generation GO:0007292 2 0.070
cellular macromolecular complex assembly GO:0034622 324 0.070
nucleotide catabolic process GO:0009166 408 0.067
atp synthesis coupled electron transport GO:0042773 4 0.067
lipid metabolic process GO:0006629 381 0.062
Worm
ion transmembrane transport GO:0034220 338 0.061
purine nucleoside catabolic process GO:0006152 398 0.061
ribonucleoside monophosphate catabolic process GO:0009158 158 0.058
organophosphate catabolic process GO:0046434 430 0.058
oxidation reduction process GO:0055114 396 0.058
regulation of neuroblast proliferation GO:1902692 3 0.057
nucleoside monophosphate catabolic process GO:0009125 159 0.057
monovalent inorganic cation transport GO:0015672 128 0.055
inorganic ion transmembrane transport GO:0098660 231 0.054
nucleoside catabolic process GO:0009164 408 0.053
positive regulation of developmental process GO:0051094 314 0.052
purine ribonucleotide biosynthetic process GO:0009152 79 0.051
regulation of cell differentiation GO:0045595 393 0.048
negative regulation of cell proliferation GO:0008285 228 0.047
cardiovascular system development GO:0072358 262 0.046
carbohydrate derivative biosynthetic process GO:1901137 207 0.045
inorganic cation transmembrane transport GO:0098662 194 0.045
fatty acid metabolic process GO:0006631 115 0.044
ribonucleoside triphosphate catabolic process GO:0009203 391 0.042
transmembrane transport GO:0055085 399 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.040
blood vessel morphogenesis GO:0048514 162 0.039
negative regulation of multicellular organismal process GO:0051241 317 0.038
mitochondrial respiratory chain complex iii assembly GO:0034551 4 0.038
purine nucleotide catabolic process GO:0006195 405 0.036
nucleoside phosphate biosynthetic process GO:1901293 109 0.035
circulatory system development GO:0072359 262 0.035
lipid biosynthetic process GO:0008610 177 0.035
nonribosomal peptide biosynthetic process GO:0019184 4 0.034
ribonucleotide catabolic process GO:0009261 405 0.033
growth GO:0040007 202 0.033
purine containing compound biosynthetic process GO:0072522 88 0.033
negative regulation of stem cell proliferation GO:2000647 3 0.033
glycosyl compound catabolic process GO:1901658 413 0.033
nucleoside triphosphate catabolic process GO:0009143 394 0.033
cellular amine metabolic process GO:0044106 41 0.032
purine containing compound catabolic process GO:0072523 411 0.032
mitochondrion organization GO:0007005 156 0.032
cellular amino acid metabolic process GO:0006520 116 0.031
anatomical structure formation involved in morphogenesis GO:0048646 284 0.030
negative regulation of cell differentiation GO:0045596 171 0.029
ribonucleotide biosynthetic process GO:0009260 81 0.029
cation transport GO:0006812 331 0.028
angiogenesis GO:0001525 147 0.027
regulation of growth GO:0040008 165 0.027
cellular lipid metabolic process GO:0044255 303 0.026
response to oxygen containing compound GO:1901700 369 0.026
blood vessel development GO:0001568 172 0.026
negative regulation of cell development GO:0010721 48 0.026
hydrogen ion transmembrane transport GO:1902600 15 0.025
cell development GO:0048468 328 0.025
carboxylic acid biosynthetic process GO:0046394 97 0.024
sulfur compound biosynthetic process GO:0044272 38 0.024
negative regulation of developmental process GO:0051093 247 0.024
glutathione biosynthetic process GO:0006750 4 0.023
regulation of cell development GO:0060284 161 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
negative regulation of neural precursor cell proliferation GO:2000178 1 0.023
nucleotide biosynthetic process GO:0009165 109 0.022
ribose phosphate biosynthetic process GO:0046390 82 0.022
mating GO:0007618 1 0.021
sulfur compound metabolic process GO:0006790 101 0.020
amine metabolic process GO:0009308 44 0.020
organic acid biosynthetic process GO:0016053 97 0.019
cellular respiration GO:0045333 21 0.019
regeneration GO:0031099 4 0.019
small molecule biosynthetic process GO:0044283 157 0.018
nucleoside triphosphate biosynthetic process GO:0009142 20 0.018
monocarboxylic acid biosynthetic process GO:0072330 67 0.018
vesicle mediated transport GO:0016192 371 0.018
hydrogen transport GO:0006818 23 0.018
cellular modified amino acid metabolic process GO:0006575 64 0.018
immune response GO:0006955 307 0.018
cellular ketone metabolic process GO:0042180 80 0.017
glycosyl compound biosynthetic process GO:1901659 27 0.017
cellular protein complex assembly GO:0043623 188 0.017
response to reactive oxygen species GO:0000302 61 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
response to oxidative stress GO:0006979 121 0.016
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.016
lipid localization GO:0010876 106 0.016
Worm
negative regulation of catalytic activity GO:0043086 335 0.015
neurogenesis GO:0022008 169 0.015
stem cell proliferation GO:0072089 25 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
embryo development GO:0009790 123 0.014
Worm
memory GO:0007613 3 0.014
regulation of transferase activity GO:0051338 355 0.014
regulation of cell cycle GO:0051726 393 0.014
regulation of neurogenesis GO:0050767 82 0.014
membrane organization GO:0061024 292 0.014
single organism cellular localization GO:1902580 332 0.014
segmentation GO:0035282 4 0.014
protein localization to membrane GO:0072657 160 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
regulation of nervous system development GO:0051960 88 0.013
maintenance of location GO:0051235 112 0.013
Worm
glutathione metabolic process GO:0006749 20 0.013
positive regulation of growth GO:0045927 58 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
response to abiotic stimulus GO:0009628 336 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.012
generation of neurons GO:0048699 152 0.012
neuromuscular junction development GO:0007528 3 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
ribonucleoside biosynthetic process GO:0042455 25 0.012
innate immune response GO:0045087 178 0.012
ras protein signal transduction GO:0007265 73 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
spinal cord development GO:0021510 4 0.012
atp biosynthetic process GO:0006754 11 0.012
regulation of kinase activity GO:0043549 314 0.012
protein localization to organelle GO:0033365 280 0.012
protein catabolic process GO:0030163 325 0.012
cytoplasmic transport GO:0016482 379 0.012
oocyte development GO:0048599 1 0.012
chromatin organization GO:0006325 351 0.011
cellular amide metabolic process GO:0043603 69 0.011
respiratory electron transport chain GO:0022904 7 0.011
microtubule based process GO:0007017 210 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
cellular component morphogenesis GO:0032989 314 0.011
positive regulation of cellular amine metabolic process GO:0033240 7 0.011
negative regulation of nervous system development GO:0051961 28 0.011
lipid oxidation GO:0034440 33 0.011
regulation of protein maturation GO:1903317 150 0.011
negative regulation of cell death GO:0060548 345 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
protein modification by small protein conjugation GO:0032446 342 0.011
regulation of protein kinase activity GO:0045859 289 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
intracellular protein transport GO:0006886 270 0.011
blastoderm segmentation GO:0007350 2 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
positive regulation of transport GO:0051050 336 0.010
spermatid differentiation GO:0048515 4 0.010
purine nucleoside biosynthetic process GO:0042451 23 0.010
regulation of protein processing GO:0070613 150 0.010
purine ribonucleoside biosynthetic process GO:0046129 23 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
hindbrain development GO:0030902 3 0.010
negative regulation of protein processing GO:0010955 142 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
oxidative phosphorylation GO:0006119 10 0.010
negative regulation of neurogenesis GO:0050768 26 0.010
protein processing GO:0016485 226 0.010
protein targeting GO:0006605 187 0.010

NDUFS4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.067
inherited metabolic disorder DOID:655 242 0.048
mitochondrial metabolism disease DOID:700 29 0.033
leigh disease DOID:3652 16 0.021
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
central nervous system disease DOID:331 186 0.013
nervous system disease DOID:863 431 0.013
sensory system disease DOID:0050155 203 0.012