Homo sapiens

7 known processes

C1R

complement component 1, r subcomponent

C1R biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of protein activation cascade GO:2000258 7 1.000
Human
complement activation lectin pathway GO:0001867 7 1.000
Human
negative regulation of complement activation GO:0045916 7 1.000
Human
protein activation cascade GO:0072376 22 1.000
Human
regulation of protein activation cascade GO:2000257 8 0.999
Human
complement activation GO:0006956 19 0.998
Human
negative regulation of humoral immune response GO:0002921 7 0.998
Human
negative regulation of complement activation lectin pathway GO:0001869 2 0.993
regulation of complement activation lectin pathway GO:0001868 2 0.917
negative regulation of plasminogen activation GO:0010757 4 0.846
protein processing GO:0016485 226 0.741
Human
negative regulation of blood coagulation GO:0030195 22 0.717
regulation of complement activation GO:0030449 8 0.714
Human
humoral immune response GO:0006959 49 0.682
Human
response to camp GO:0051591 25 0.581
negative regulation of immune response GO:0050777 40 0.578
Human
acute inflammatory response GO:0002526 21 0.577
Human
positive regulation of immune response GO:0050778 159 0.556
Human
inflammatory response GO:0006954 79 0.554
Human
negative regulation of protein processing GO:0010955 142 0.539
Human
positive regulation of immune system process GO:0002684 283 0.533
Human
negative regulation of immune effector process GO:0002698 38 0.514
Human
innate immune response GO:0045087 178 0.513
Human
regulation of blood coagulation GO:0030193 42 0.495
defense response GO:0006952 315 0.481
Human
positive regulation of cytokine production GO:0001819 167 0.449
regulation of defense response GO:0031347 154 0.426
Human
response to organophosphorus GO:0046683 41 0.424
negative regulation of protein metabolic process GO:0051248 391 0.419
Human
plasminogen activation GO:0031639 11 0.401
response to purine containing compound GO:0014074 40 0.394
regulation of protein processing GO:0070613 150 0.392
Human
immune response GO:0006955 307 0.391
Human
regulation of acute inflammatory response GO:0002673 13 0.389
Human
regulation of cytokine production GO:0001817 232 0.389
immune effector process GO:0002252 159 0.385
Human
regulation of immune effector process GO:0002697 91 0.384
Human
regulation of protein maturation GO:1903317 150 0.360
Human
negative regulation of protein maturation GO:1903318 142 0.343
Human
regulation of response to external stimulus GO:0032101 222 0.313
Human
negative regulation of multicellular organismal process GO:0051241 317 0.292
glial cell differentiation GO:0010001 11 0.276
response to oxygen containing compound GO:1901700 369 0.272
cytokine production GO:0001816 247 0.259
negative regulation of hemostasis GO:1900047 22 0.250
response to organic cyclic compound GO:0014070 204 0.242
response to nitrogen compound GO:1901698 184 0.241
negative regulation of immune system process GO:0002683 136 0.226
Human
activation of immune response GO:0002253 114 0.225
Human
response to wounding GO:0009611 168 0.224
Human
signal transduction by phosphorylation GO:0023014 297 0.206
response to organonitrogen compound GO:0010243 156 0.205
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.204
regulation of humoral immune response GO:0002920 11 0.194
Human
protein maturation GO:0051604 233 0.178
Human
positive regulation of phosphorylation GO:0042327 394 0.161
negative regulation of locomotion GO:0040013 118 0.160
regulation of inflammatory response GO:0050727 46 0.147
Human
regulation of innate immune response GO:0045088 97 0.130
mapk cascade GO:0000165 288 0.123
regulation of cell differentiation GO:0045595 393 0.117
regulation of peptidase activity GO:0052547 180 0.111
regulation of erk1 and erk2 cascade GO:0070372 99 0.111
nervous system development GO:0007399 293 0.102
hemostasis GO:0007599 76 0.101
negative regulation of cellular protein metabolic process GO:0032269 353 0.097
cellular lipid metabolic process GO:0044255 303 0.096
positive regulation of mesenchymal stem cell differentiation GO:2000741 4 0.096
regulation of immune response GO:0050776 201 0.094
Human
negative regulation of response to wounding GO:1903035 47 0.094
positive regulation of cellular amine metabolic process GO:0033240 7 0.090
positive regulation of blood coagulation GO:0030194 11 0.085
positive regulation of leukocyte activation GO:0002696 80 0.085
negative regulation of platelet aggregation GO:0090331 3 0.085
multicellular organismal macromolecule metabolic process GO:0044259 29 0.082
regulation of mapk cascade GO:0043408 262 0.082
neurogenesis GO:0022008 169 0.081
negative regulation of cell motility GO:2000146 104 0.080
negative regulation of hydrolase activity GO:0051346 182 0.078
chemical homeostasis GO:0048878 306 0.077
regulation of secretion by cell GO:1903530 177 0.075
regulation of cellular response to stress GO:0080135 244 0.075
gliogenesis GO:0042063 21 0.075
wound healing GO:0042060 115 0.074
negative regulation of proteolysis GO:0045861 132 0.073
regulation of cellular amine metabolic process GO:0033238 11 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
multicellular organismal metabolic process GO:0044236 34 0.071
peptidyl tyrosine phosphorylation GO:0018108 170 0.068
positive regulation of protein kinase activity GO:0045860 190 0.066
positive regulation of cell differentiation GO:0045597 211 0.065
regulation of protein secretion GO:0050708 86 0.064
negative regulation of coagulation GO:0050819 24 0.064
cellular response to cytokine stimulus GO:0071345 181 0.063
negative regulation of defense response GO:0031348 47 0.062
regulation of response to wounding GO:1903034 101 0.060
Human
positive regulation of acute inflammatory response GO:0002675 2 0.059
cellular response to oxygen containing compound GO:1901701 276 0.058
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.053
peptidyl tyrosine modification GO:0018212 170 0.051
renal albumin absorption GO:0097018 1 0.051
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.051
response to external biotic stimulus GO:0043207 261 0.049
positive regulation of developmental process GO:0051094 314 0.049
positive regulation of renal albumin absorption GO:2000534 1 0.048
negative regulation of phosphate metabolic process GO:0045936 267 0.048
positive regulation of hemostasis GO:1900048 11 0.047
positive regulation of protein phosphorylation GO:0001934 313 0.046
cellular carbohydrate metabolic process GO:0044262 84 0.046
protein oligomerization GO:0051259 173 0.046
transmembrane transport GO:0055085 399 0.045
zymogen activation GO:0031638 70 0.045
jnk cascade GO:0007254 80 0.044
regulation of cell migration GO:0030334 289 0.043
osteoblast differentiation GO:0001649 92 0.043
negative regulation of endopeptidase activity GO:0010951 84 0.042
positive regulation of lymphocyte activation GO:0051251 73 0.042
positive regulation of t cell activation GO:0050870 54 0.041
regulation of cell motility GO:2000145 299 0.040
regulation of proteolysis GO:0030162 293 0.039
negative regulation of innate immune response GO:0045824 18 0.039
single organism carbohydrate metabolic process GO:0044723 193 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.039
positive regulation of cell death GO:0010942 263 0.039
single organismal cell cell adhesion GO:0016337 148 0.038
ossification GO:0001503 121 0.038
positive regulation of kinase activity GO:0033674 204 0.038
blood vessel development GO:0001568 172 0.037
response to abiotic stimulus GO:0009628 336 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
complement activation classical pathway GO:0006958 3 0.036
collagen metabolic process GO:0032963 28 0.036
positive regulation of t cell proliferation GO:0042102 33 0.036
cellular protein catabolic process GO:0044257 261 0.036
divalent inorganic cation homeostasis GO:0072507 136 0.035
regulation of wound healing GO:0061041 56 0.035
cellular amino acid metabolic process GO:0006520 116 0.034
regulation of stress activated mapk cascade GO:0032872 84 0.034
regulation of fibrinolysis GO:0051917 8 0.034
leukocyte activation GO:0045321 164 0.034
negative regulation of developmental process GO:0051093 247 0.032
ion transmembrane transport GO:0034220 338 0.032
t cell activation GO:0042110 99 0.032
negative regulation of phagocytosis GO:0050765 4 0.031
cellular amine metabolic process GO:0044106 41 0.031
regulation of establishment of protein localization GO:0070201 242 0.031
positive regulation of transport GO:0051050 336 0.030
positive regulation of response to wounding GO:1903036 28 0.030
regulation of macrophage chemotaxis GO:0010758 4 0.030
negative regulation of cell migration GO:0030336 102 0.030
gastrulation GO:0007369 51 0.030
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.030
positive regulation of humoral immune response GO:0002922 3 0.029
cytokine secretion GO:0050663 64 0.028
cell activation GO:0001775 213 0.028
positive regulation of protein transport GO:0051222 135 0.028
regulation of transferase activity GO:0051338 355 0.028
positive regulation of mineralocorticoid secretion GO:2000857 1 0.027
cellular ketone metabolic process GO:0042180 80 0.027
negative regulation of protein modification process GO:0031400 200 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.026
regulation of vasculature development GO:1901342 97 0.026
inorganic anion transmembrane transport GO:0098661 47 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
positive regulation of wound healing GO:0090303 20 0.025
response to interferon gamma GO:0034341 39 0.025
negative regulation of homotypic cell cell adhesion GO:0034111 3 0.025
i kappab kinase nf kappab signaling GO:0007249 166 0.025
positive regulation of transferase activity GO:0051347 227 0.025
regulation of ossification GO:0030278 58 0.025
positive regulation of apoptotic process GO:0043065 246 0.025
vesicle mediated transport GO:0016192 371 0.024
regulation of platelet aggregation GO:0090330 4 0.024
positive regulation of corticosteroid hormone secretion GO:2000848 5 0.024
carbohydrate metabolic process GO:0005975 207 0.024
negative regulation of intracellular signal transduction GO:1902532 183 0.024
t cell proliferation GO:0042098 45 0.024
positive regulation of jnk cascade GO:0046330 52 0.024
positive regulation of cytoskeleton organization GO:0051495 83 0.024
positive regulation of secretion by cell GO:1903532 108 0.023
regulation of glucose metabolic process GO:0010906 28 0.023
amine metabolic process GO:0009308 44 0.023
glucose metabolic process GO:0006006 45 0.023
positive regulation of cell activation GO:0050867 81 0.022
positive regulation of secretion GO:0051047 116 0.022
mature natural killer cell chemotaxis GO:0035782 1 0.022
ion homeostasis GO:0050801 230 0.022
monosaccharide metabolic process GO:0005996 74 0.021
sulfur compound metabolic process GO:0006790 101 0.021
negative regulation of cellular component movement GO:0051271 106 0.021
lipid transport GO:0006869 90 0.021
negative regulation of vasculature development GO:1901343 43 0.020
negative regulation of blood pressure GO:0045776 3 0.020
post embryonic development GO:0009791 2 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
positive regulation of mononuclear cell proliferation GO:0032946 47 0.020
single organism cell adhesion GO:0098602 179 0.020
regulation of locomotion GO:0040012 329 0.019
cellular amide metabolic process GO:0043603 69 0.019
negative regulation of protein phosphorylation GO:0001933 140 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.019
chondroitin sulfate metabolic process GO:0030204 7 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
hindbrain development GO:0030902 3 0.018
regulation of leukocyte activation GO:0002694 115 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
regulation of kinase activity GO:0043549 314 0.018
multi organism cellular process GO:0044764 156 0.018
hexose metabolic process GO:0019318 55 0.018
lipid localization GO:0010876 106 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
system process GO:0003008 349 0.018
rho protein signal transduction GO:0007266 26 0.017
regulation of secretion GO:0051046 194 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
mitochondrion organization GO:0007005 156 0.017
multicellular organismal aging GO:0010259 3 0.017
skeletal muscle satellite cell proliferation GO:0014841 1 0.017
regulation of collagen metabolic process GO:0010712 15 0.017
negative regulation of t cell cytokine production GO:0002725 4 0.016
female gamete generation GO:0007292 2 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
regulation of tumor necrosis factor production GO:0032680 43 0.016
hormone secretion GO:0046879 65 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
negative regulation of blood vessel morphogenesis GO:2000181 41 0.016
response to inorganic substance GO:0010035 127 0.016
response to radiation GO:0009314 151 0.016
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.016
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.016
chondroitin sulfate proteoglycan metabolic process GO:0050654 10 0.016
biomineral tissue development GO:0031214 39 0.016
regulation of cellular component movement GO:0051270 334 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
positive regulation of coagulation GO:0050820 11 0.015
regulation of transmembrane transport GO:0034762 139 0.015
negative regulation of response to cytokine stimulus GO:0060761 25 0.015
response to biotic stimulus GO:0009607 276 0.015
determination of adult lifespan GO:0008340 2 0.015
cellular homeostasis GO:0019725 196 0.015
regulation of hormone secretion GO:0046883 57 0.015
cell development GO:0048468 328 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.014
cellular response to organonitrogen compound GO:0071417 124 0.014
regulation of protein localization GO:0032880 296 0.014
apoptotic signaling pathway GO:0097190 268 0.014
positive regulation of catabolic process GO:0009896 310 0.014
biological adhesion GO:0022610 331 0.014
spermatid differentiation GO:0048515 4 0.014
phospholipid metabolic process GO:0006644 99 0.014
oxidation reduction process GO:0055114 396 0.014
response to axon injury GO:0048678 1 0.014
negative regulation of transport GO:0051051 176 0.014
ras protein signal transduction GO:0007265 73 0.014
positive regulation of multicellular organismal metabolic process GO:0044253 11 0.014
angiogenesis GO:0001525 147 0.014
lipid metabolic process GO:0006629 381 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
secretion GO:0046903 254 0.013
interferon gamma production GO:0032609 39 0.013
negative regulation of peptidase activity GO:0010466 91 0.013
regulation of chemokine production GO:0032642 31 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.013
regulation of cell activation GO:0050865 125 0.013
regulation of renal albumin absorption GO:2000532 1 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.013
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 4 0.013
regulation of protein kinase activity GO:0045859 289 0.013
protein autophosphorylation GO:0046777 123 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
regulation of protein transport GO:0051223 213 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
cerebellum development GO:0021549 2 0.013
protein catabolic process GO:0030163 325 0.013
multi organism metabolic process GO:0044033 41 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
lipid biosynthetic process GO:0008610 177 0.013
positive regulation of steroid hormone secretion GO:2000833 6 0.012
positive regulation of nervous system development GO:0051962 54 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
peptide metabolic process GO:0006518 51 0.012
negative regulation of low density lipoprotein particle receptor biosynthetic process GO:0045715 3 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
modification of morphology or physiology of other organism GO:0035821 43 0.012
negative regulation of behavior GO:0048521 15 0.012
retinoid metabolic process GO:0001523 18 0.012
regulation of behavior GO:0050795 82 0.012
chemokine production GO:0032602 32 0.012
inorganic anion transport GO:0015698 60 0.012
extracellular structure organization GO:0043062 41 0.012
viral gene expression GO:0019080 35 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.012
cell morphogenesis GO:0000902 296 0.012
regeneration GO:0031099 4 0.012
purine containing compound catabolic process GO:0072523 411 0.012
positive regulation of chemokine production GO:0032722 22 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
mononuclear cell proliferation GO:0032943 71 0.012
regulation of osteoblast differentiation GO:0045667 38 0.012
positive regulation of organelle organization GO:0010638 195 0.011
rhythmic behavior GO:0007622 2 0.011
growth GO:0040007 202 0.011
positive regulation of activated t cell proliferation GO:0042104 11 0.011
cholesterol transport GO:0030301 39 0.011
elastic fiber assembly GO:0048251 3 0.011
circulatory system development GO:0072359 262 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.011
metal ion transport GO:0030001 272 0.011
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.011
negative regulation of tumor necrosis factor production GO:0032720 20 0.011
dicarboxylic acid metabolic process GO:0043648 29 0.011
negative regulation of insulin like growth factor receptor signaling pathway GO:0043569 4 0.011
regulation of protein catabolic process GO:0042176 155 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
response to reactive oxygen species GO:0000302 61 0.011
oogenesis GO:0048477 2 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
response to virus GO:0009615 126 0.011
negative regulation of multi organism process GO:0043901 92 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
fatty acid metabolic process GO:0006631 115 0.011
nuclear transport GO:0051169 179 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
negative regulation of leukocyte differentiation GO:1902106 24 0.011
locomotory behavior GO:0007626 1 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
calcium ion homeostasis GO:0055074 122 0.010
translation GO:0006412 132 0.010
spermatid development GO:0007286 4 0.010
metal ion homeostasis GO:0055065 169 0.010
positive regulation of osteoblast differentiation GO:0045669 23 0.010
positive regulation of mesenchymal stem cell proliferation GO:1902462 1 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
regulation of cell cycle GO:0051726 393 0.010
epithelial cell migration GO:0010631 119 0.010
regulation of lipid transport GO:0032368 44 0.010
sensory perception GO:0007600 103 0.010
neuromuscular junction development GO:0007528 3 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010

C1R disease predictions

Disease DO term ID Size Probability Func Analog Org
hemolytic anemia DOID:583 20 0.499
hemolytic uremic syndrome DOID:12554 8 0.499
immune system disease DOID:2914 155 0.499
normocytic anemia DOID:720 20 0.499
anemia DOID:2355 55 0.499
hematopoietic system disease DOID:74 100 0.499
sensory system disease DOID:0050155 203 0.171
nervous system disease DOID:863 431 0.171
eye and adnexa disease DOID:1492 150 0.137
eye disease DOID:5614 149 0.092
musculoskeletal system disease DOID:17 223 0.043
myopathy DOID:423 104 0.030
congenital muscular dystrophy DOID:0050557 22 0.030
muscular disease DOID:0080000 114 0.030
muscular dystrophy DOID:9884 51 0.030
muscle tissue disease DOID:66 113 0.030
retinal disease DOID:5679 118 0.025
retinal degeneration DOID:8466 89 0.025
macular degeneration DOID:4448 20 0.025
degeneration of macula and posterior pole DOID:2007 17 0.025
disease by infectious agent DOID:0050117 34 0.020
kidney disease DOID:557 36 0.018
urinary system disease DOID:18 40 0.018
disease of metabolism DOID:0014667 295 0.015
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
central nervous system disease DOID:331 186 0.012
connective tissue disease DOID:65 109 0.011