Homo sapiens

17 known processes

NEK7

NIMA (never in mitosis gene a)-related kinase 7

NEK7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular component organization GO:0051130 376 0.224
mitotic cell cycle GO:0000278 326 0.188
cytoplasmic transport GO:0016482 379 0.184
membrane organization GO:0061024 292 0.170
vesicle mediated transport GO:0016192 371 0.142
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.136
regulation of cell cycle GO:0051726 393 0.110
Human
segmentation GO:0035282 4 0.098
purine nucleoside triphosphate metabolic process GO:0009144 412 0.089
plasma membrane organization GO:0007009 115 0.087
organophosphate catabolic process GO:0046434 430 0.085
guanosine containing compound catabolic process GO:1901069 239 0.083
regulation of cellular component biogenesis GO:0044087 281 0.082
neuromuscular junction development GO:0007528 3 0.079
cell adhesion GO:0007155 325 0.078
purine ribonucleoside metabolic process GO:0046128 437 0.074
intracellular protein transport GO:0006886 270 0.073
regulation of vesicle mediated transport GO:0060627 130 0.072
positive regulation of mapk cascade GO:0043410 190 0.071
glycosyl compound catabolic process GO:1901658 413 0.070
ribonucleoside triphosphate metabolic process GO:0009199 412 0.070
biological adhesion GO:0022610 331 0.069
ras protein signal transduction GO:0007265 73 0.068
Human
nucleoside phosphate catabolic process GO:1901292 412 0.064
regulation of intracellular transport GO:0032386 195 0.063
negative regulation of cell proliferation GO:0008285 228 0.063
modification dependent macromolecule catabolic process GO:0043632 212 0.060
vesicle organization GO:0016050 62 0.060
regulation of purine nucleotide metabolic process GO:1900542 264 0.059
nucleoside triphosphate catabolic process GO:0009143 394 0.059
endocytosis GO:0006897 159 0.058
nucleoside catabolic process GO:0009164 408 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.057
small molecule biosynthetic process GO:0044283 157 0.057
single organism cellular localization GO:1902580 332 0.056
protein localization to membrane GO:0072657 160 0.055
positive regulation of exocytosis GO:0045921 35 0.054
regulation of nucleotide metabolic process GO:0006140 269 0.052
regulation of cytoplasmic transport GO:1903649 149 0.052
regulation of establishment of protein localization GO:0070201 242 0.052
amine metabolic process GO:0009308 44 0.051
post embryonic development GO:0009791 2 0.051
mitotic cell cycle process GO:1903047 286 0.051
regulation of nucleoside metabolic process GO:0009118 209 0.050
small gtpase mediated signal transduction GO:0007264 78 0.050
Human
purine ribonucleotide catabolic process GO:0009154 404 0.049
regulation of mitotic cell cycle GO:0007346 189 0.048
single organism membrane organization GO:0044802 268 0.048
oocyte development GO:0048599 1 0.047
anterior posterior axis specification GO:0009948 2 0.047
regulation of cellular component movement GO:0051270 334 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.046
purine nucleotide catabolic process GO:0006195 405 0.044
protein localization to plasma membrane GO:0072659 93 0.044
gtp catabolic process GO:0006184 237 0.044
single organism cell adhesion GO:0098602 179 0.043
purine containing compound catabolic process GO:0072523 411 0.043
regulation of cell cycle process GO:0010564 266 0.042
regulation of locomotion GO:0040012 329 0.041
somitogenesis GO:0001756 2 0.040
positive regulation of organelle organization GO:0010638 195 0.040
oocyte differentiation GO:0009994 2 0.039
negative regulation of transport GO:0051051 176 0.039
dephosphorylation GO:0016311 209 0.039
muscle structure development GO:0061061 98 0.039
cell growth GO:0016049 160 0.038
actin cytoskeleton organization GO:0030036 207 0.038
organ morphogenesis GO:0009887 147 0.038
leukocyte migration GO:0050900 107 0.037
purine ribonucleoside catabolic process GO:0046130 398 0.037
cellular protein complex assembly GO:0043623 188 0.037
negative regulation of cell cycle GO:0045786 193 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.037
positive regulation of transport GO:0051050 336 0.036
negative regulation of catalytic activity GO:0043086 335 0.036
ribonucleoside catabolic process GO:0042454 406 0.036
regulation of proteolysis GO:0030162 293 0.035
cellular amino acid metabolic process GO:0006520 116 0.035
enzyme linked receptor protein signaling pathway GO:0007167 303 0.035
positive regulation of gtp catabolic process GO:0033126 166 0.034
guanosine containing compound metabolic process GO:1901068 244 0.033
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
lipid biosynthetic process GO:0008610 177 0.032
cell cycle phase transition GO:0044770 173 0.032
cell projection organization GO:0030030 252 0.032
cellular response to oxygen containing compound GO:1901701 276 0.032
cellular macromolecule catabolic process GO:0044265 380 0.032
endomembrane system organization GO:0010256 196 0.032
golgi vesicle transport GO:0048193 80 0.032
positive regulation of cell development GO:0010720 92 0.032
nucleoside triphosphate metabolic process GO:0009141 422 0.031
regulation of nucleotide catabolic process GO:0030811 205 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
negative regulation of multicellular organismal process GO:0051241 317 0.031
regulation of leukocyte migration GO:0002685 63 0.031
regulation of protein stability GO:0031647 87 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
lipid metabolic process GO:0006629 381 0.030
regulation of protein localization GO:0032880 296 0.030
regulation of mapk cascade GO:0043408 262 0.030
female gamete generation GO:0007292 2 0.030
negative regulation of smoothened signaling pathway GO:0045879 3 0.029
organophosphate biosynthetic process GO:0090407 163 0.029
actin filament based process GO:0030029 224 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
nitrogen compound transport GO:0071705 191 0.029
positive regulation of nucleotide catabolic process GO:0030813 185 0.029
regulation of secretion GO:0051046 194 0.029
blastoderm segmentation GO:0007350 2 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.029
cellular component morphogenesis GO:0032989 314 0.029
negative regulation of protein metabolic process GO:0051248 391 0.029
positive regulation of nucleotide metabolic process GO:0045981 230 0.028
establishment of protein localization to membrane GO:0090150 121 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
cell morphogenesis GO:0000902 296 0.028
positive regulation of phosphorylation GO:0042327 394 0.027
epithelium development GO:0060429 227 0.027
Human
cellular response to endogenous stimulus GO:0071495 336 0.027
response to oxygen containing compound GO:1901700 369 0.027
gtp metabolic process GO:0046039 239 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.027
neurotransmitter secretion GO:0007269 4 0.026
cell activation GO:0001775 213 0.026
embryo development GO:0009790 123 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
cellular lipid metabolic process GO:0044255 303 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
regulation of cytoskeleton organization GO:0051493 177 0.024
regulation of cellular response to stress GO:0080135 244 0.024
circadian behavior GO:0048512 2 0.024
nucleotide catabolic process GO:0009166 408 0.024
positive regulation of immune system process GO:0002684 283 0.024
regulation of mitotic cell cycle phase transition GO:1901990 118 0.024
mitochondrion organization GO:0007005 156 0.024
rho protein signal transduction GO:0007266 26 0.023
skin development GO:0043588 76 0.023
regulation of transferase activity GO:0051338 355 0.023
mitotic nuclear division GO:0007067 119 0.023
regulation of cell adhesion GO:0030155 166 0.023
immune response GO:0006955 307 0.023
peptide transport GO:0015833 74 0.023
regulation of protein kinase activity GO:0045859 289 0.023
cell development GO:0048468 328 0.023
endosomal transport GO:0016197 129 0.022
regulation of gtpase activity GO:0043087 180 0.022
regulation of cell migration GO:0030334 289 0.022
apoptotic signaling pathway GO:0097190 268 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
positive regulation of cell proliferation GO:0008284 301 0.022
Human
regulation of ras protein signal transduction GO:0046578 155 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
embryonic morphogenesis GO:0048598 85 0.022
negative regulation of cytoplasmic transport GO:1903650 46 0.022
organelle assembly GO:0070925 176 0.022
signal transduction by phosphorylation GO:0023014 297 0.021
response to light stimulus GO:0009416 87 0.021
response to growth factor GO:0070848 205 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
modification dependent protein catabolic process GO:0019941 209 0.021
regulation of cell cycle phase transition GO:1901987 126 0.020
regulation of jnk cascade GO:0046328 73 0.020
nuclear transport GO:0051169 179 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
cation transport GO:0006812 331 0.019
regulation of gtp catabolic process GO:0033124 180 0.019
protein stabilization GO:0050821 64 0.019
exocytosis GO:0006887 71 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
erk1 and erk2 cascade GO:0070371 104 0.019
organelle fission GO:0048285 149 0.019
negative regulation of protein modification process GO:0031400 200 0.019
cellular ketone metabolic process GO:0042180 80 0.019
rhythmic behavior GO:0007622 2 0.019
oogenesis GO:0048477 2 0.018
regulation of stress activated mapk cascade GO:0032872 84 0.018
establishment of protein localization to plasma membrane GO:0090002 68 0.018
spermatid differentiation GO:0048515 4 0.018
positive regulation of catabolic process GO:0009896 310 0.018
protein autophosphorylation GO:0046777 123 0.018
neural tube closure GO:0001843 3 0.018
apoptotic process involved in morphogenesis GO:0060561 3 0.018
regulation of ras gtpase activity GO:0032318 128 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
regulation of secretion by cell GO:1903530 177 0.018
positive regulation of cell adhesion GO:0045785 84 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
convergent extension GO:0060026 1 0.018
cardiovascular system development GO:0072358 262 0.018
primary neural tube formation GO:0014020 3 0.018
regulation of multi organism process GO:0043900 157 0.018
positive regulation of cytoskeleton organization GO:0051495 83 0.017
leukocyte mediated immunity GO:0002443 59 0.017
cell morphogenesis involved in differentiation GO:0000904 144 0.017
immune effector process GO:0002252 159 0.017
regulation of proteasomal protein catabolic process GO:0061136 87 0.017
maintenance of cell polarity GO:0030011 2 0.017
striated muscle tissue development GO:0014706 59 0.017
microtubule based process GO:0007017 210 0.017
tripartite regional subdivision GO:0007351 2 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
stress activated protein kinase signaling cascade GO:0031098 94 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
metal ion transport GO:0030001 272 0.016
regulation of cell differentiation GO:0045595 393 0.016
negative regulation of kinase activity GO:0033673 106 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
cellular protein catabolic process GO:0044257 261 0.016
positive regulation of sequestering of triglyceride GO:0010890 3 0.016
cell junction organization GO:0034330 79 0.016
developmental programmed cell death GO:0010623 3 0.015
regulation of neuron projection development GO:0010975 57 0.015
regulation of cell development GO:0060284 161 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
positive regulation of cell death GO:0010942 263 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
tissue morphogenesis GO:0048729 96 0.015
chordate embryonic development GO:0043009 34 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
regulation of growth rate GO:0040009 1 0.015
cell projection assembly GO:0030031 126 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
spermatid development GO:0007286 4 0.015
cilium assembly GO:0042384 63 0.015
microtubule organizing center organization GO:0031023 62 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
cellular component assembly involved in morphogenesis GO:0010927 73 0.015
protein catabolic process GO:0030163 325 0.015
muscle cell differentiation GO:0042692 63 0.014
response to abiotic stimulus GO:0009628 336 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
membrane fusion GO:0061025 43 0.014
regulation of protein complex assembly GO:0043254 147 0.014
embryonic neurocranium morphogenesis GO:0048702 1 0.014
regulation of kinase activity GO:0043549 314 0.014
adult locomotory behavior GO:0008344 1 0.014
negative regulation of transferase activity GO:0051348 124 0.014
regulation of heart growth GO:0060420 4 0.014
negative regulation of mitotic cell cycle GO:0045930 102 0.014
cell cell junction organization GO:0045216 69 0.014
organic acid biosynthetic process GO:0016053 97 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
calcium ion homeostasis GO:0055074 122 0.013
anion transport GO:0006820 161 0.013
cell part morphogenesis GO:0032990 137 0.013
regulation of nucleocytoplasmic transport GO:0046822 98 0.013
vacuolar transport GO:0007034 34 0.013
memory GO:0007613 3 0.013
actin filament organization GO:0007015 128 0.013
mapk cascade GO:0000165 288 0.013
morphogenesis of a polarized epithelium GO:0001738 3 0.013
single organismal cell cell adhesion GO:0016337 148 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
heart development GO:0007507 95 0.013
regulation of cell projection organization GO:0031344 107 0.013
negative regulation of jak stat cascade GO:0046426 4 0.013
epithelial cell proliferation GO:0050673 128 0.013
leukocyte cell cell adhesion GO:0007159 37 0.013
regulation of immune effector process GO:0002697 91 0.013
peptidyl serine modification GO:0018209 106 0.013
Human
cellular amide metabolic process GO:0043603 69 0.013
positive regulation of transferase activity GO:0051347 227 0.013
inner ear morphogenesis GO:0042472 4 0.013
metal ion homeostasis GO:0055065 169 0.013
regulation of cell motility GO:2000145 299 0.012
growth GO:0040007 202 0.012
neurogenesis GO:0022008 169 0.012
positive regulation of phagocytosis engulfment GO:0060100 1 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
maintenance of location in cell GO:0051651 62 0.012
response to radiation GO:0009314 151 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
Human
negative regulation of phosphorylation GO:0042326 174 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
multicellular organismal aging GO:0010259 3 0.012
positive regulation of lymphocyte activation GO:0051251 73 0.012
jnk cascade GO:0007254 80 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
protein localization to nucleus GO:0034504 136 0.012
determination of adult lifespan GO:0008340 2 0.012
cilium organization GO:0044782 68 0.012
regulation of microtubule based process GO:0032886 74 0.012
glycerolipid metabolic process GO:0046486 107 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
positive regulation of leukocyte activation GO:0002696 80 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
response to transforming growth factor beta GO:0071559 94 0.012
leukocyte activation GO:0045321 164 0.011
immune system development GO:0002520 195 0.011
regulation of phosphatase activity GO:0010921 81 0.011
regulation of neurotransmitter secretion GO:0046928 3 0.011
negative regulation of secretion by cell GO:1903531 52 0.011
mitochondrion distribution GO:0048311 3 0.011
axis elongation GO:0003401 4 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
secretion by cell GO:0032940 226 0.011
negative regulation of growth GO:0045926 97 0.011
neuron projection development GO:0031175 106 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
vacuole organization GO:0007033 44 0.011
hippo signaling GO:0035329 20 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.011
negative regulation of intracellular transport GO:0032387 60 0.011
circulatory system development GO:0072359 262 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
regulation of endocytosis GO:0030100 72 0.011
hindbrain development GO:0030902 3 0.011
protein targeting GO:0006605 187 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
regulation of phagocytosis engulfment GO:0060099 2 0.011
cellular amine metabolic process GO:0044106 41 0.011
positive regulation of neurogenesis GO:0050769 49 0.011
response to peptide hormone GO:0043434 61 0.011
protein maturation GO:0051604 233 0.010
chemical homeostasis GO:0048878 306 0.010
locomotory behavior GO:0007626 1 0.010
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.010
cation homeostasis GO:0055080 189 0.010
regulation of immune response GO:0050776 201 0.010
synaptic vesicle recycling GO:0036465 3 0.010
positive regulation of growth GO:0045927 58 0.010
morphogenesis of an epithelium GO:0002009 60 0.010
negative regulation of developmental process GO:0051093 247 0.010
coagulation GO:0050817 78 0.010
sterol metabolic process GO:0016125 28 0.010
regulation of neurogenesis GO:0050767 82 0.010
regulation of synaptic vesicle transport GO:1902803 3 0.010

NEK7 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.045
disease of cellular proliferation DOID:14566 174 0.045
organ system cancer DOID:0050686 164 0.045
musculoskeletal system disease DOID:17 223 0.026
connective tissue disease DOID:65 109 0.021
central nervous system disease DOID:331 186 0.013
nervous system disease DOID:863 431 0.013
bone disease DOID:0080001 88 0.012
sensory system disease DOID:0050155 203 0.012
neurodegenerative disease DOID:1289 102 0.010