|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.996
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.988
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.932
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.601
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.540
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.528
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.458
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.409
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.374
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.342
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.292
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.125
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.113
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.110
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.103
|
Mouse |
|
hindbrain development
|
GO:0030902 |
3 |
0.092
|
Mouse |
|
post embryonic development
|
GO:0009791 |
2 |
0.078
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.077
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.074
|
|
|
organ formation
|
GO:0048645 |
3 |
0.066
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.066
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.064
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.060
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.057
|
|
|
secretion
|
GO:0046903 |
254 |
0.056
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.055
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.053
|
Mouse |
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.052
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.051
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.051
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.049
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.048
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.048
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.048
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.046
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.045
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.045
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.044
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.044
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.043
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.042
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.041
|
Worm |
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.040
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.039
|
|
|
mating
|
GO:0007618 |
1 |
0.038
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.037
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.035
|
Mouse |
|
cation homeostasis
|
GO:0055080 |
189 |
0.035
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.035
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.034
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.034
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.034
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.034
|
|
|
cell development
|
GO:0048468 |
328 |
0.033
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.033
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.033
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.033
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.032
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.032
|
Mouse |
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.031
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.031
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.031
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.030
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.030
|
Mouse |
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.030
|
Mouse |
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.030
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.030
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.029
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.028
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.027
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.027
|
|
|
viral process
|
GO:0016032 |
146 |
0.027
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.027
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.027
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.026
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.026
|
Worm |
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.026
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.026
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.026
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.025
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.025
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.025
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.025
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.025
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.024
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.024
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.024
|
Mouse |
|
chromatin organization
|
GO:0006325 |
351 |
0.024
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.024
|
Mouse |
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.024
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.024
|
Mouse |
|
organelle fission
|
GO:0048285 |
149 |
0.023
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.023
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.023
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.023
|
Mouse |
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.022
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.022
|
|
|
segmentation
|
GO:0035282 |
4 |
0.022
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.022
|
Mouse |
|
myoblast differentiation
|
GO:0045445 |
21 |
0.022
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.022
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.022
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.022
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.022
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.022
|
|
|
embryo development
|
GO:0009790 |
123 |
0.021
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.021
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.021
|
Mouse |
|
behavior
|
GO:0007610 |
112 |
0.021
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.021
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.021
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.021
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.021
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.021
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.021
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.021
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.020
|
Mouse |
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.020
|
|
|
protein processing
|
GO:0016485 |
226 |
0.020
|
Mouse |
|
regulation of growth
|
GO:0040008 |
165 |
0.020
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.020
|
|
|
cell division
|
GO:0051301 |
168 |
0.019
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.019
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.019
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.019
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.019
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.018
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.018
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.018
|
Mouse |
|
regulation of protein stability
|
GO:0031647 |
87 |
0.018
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.018
|
|
|
dna repair
|
GO:0006281 |
198 |
0.018
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.018
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.018
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.018
|
|
|
cell growth
|
GO:0016049 |
160 |
0.018
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.018
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.018
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.018
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.017
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.017
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.017
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.017
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.017
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.017
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.017
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.017
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.017
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.017
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.016
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.016
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.016
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.016
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.016
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.016
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.016
|
|
|
immune response
|
GO:0006955 |
307 |
0.016
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.016
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.016
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.016
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.016
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.016
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.016
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.016
|
Mouse |
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.016
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.015
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.015
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.015
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.015
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.015
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.015
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.015
|
Mouse |
|
regulation of protein localization
|
GO:0032880 |
296 |
0.015
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.015
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.015
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.015
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.015
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.015
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.015
|
|
|
regeneration
|
GO:0031099 |
4 |
0.015
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.015
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.014
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.014
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.014
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.014
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.014
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.014
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.014
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.014
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.014
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.014
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.014
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.014
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.014
|
|
|
defense response
|
GO:0006952 |
315 |
0.014
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.014
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.013
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.013
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.013
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.013
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.013
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.013
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.013
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.013
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.013
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.013
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.013
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.013
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.013
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.013
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.013
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.013
|
Mouse |
|
nuclear migration
|
GO:0007097 |
1 |
0.013
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.013
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.013
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.013
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.013
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.012
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.012
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.012
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.012
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.012
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.012
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.012
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.012
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.012
|
|
|
growth
|
GO:0040007 |
202 |
0.012
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.012
|
|
|
protein k11 linked ubiquitination
|
GO:0070979 |
24 |
0.012
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.012
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.012
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.012
|
|
|
aging
|
GO:0007568 |
66 |
0.012
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.012
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.012
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.011
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.011
|
Mouse |
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.011
|
Worm |
|
spermatid differentiation
|
GO:0048515 |
4 |
0.011
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.011
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.011
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.011
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.011
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.011
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.011
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.011
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.011
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.011
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.011
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.011
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.011
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.011
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.011
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.011
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.011
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.011
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.011
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.011
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.011
|
|
|
rna interference
|
GO:0016246 |
4 |
0.010
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.010
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.010
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.010
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.010
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.010
|
|
|
amide transport
|
GO:0042886 |
76 |
0.010
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.010
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.010
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.010
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.010
|
Mouse |
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.010
|
Mouse |
|
calcium ion transport
|
GO:0006816 |
147 |
0.010
|
|