Homo sapiens

20 known processes

RECQL

RecQ protein-like (DNA helicase Q1-like)

(Aliases: RecQ1,RECQL1)

RECQL biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nfat protein import into nucleus GO:0051533 3 0.477
nls bearing protein import into nucleus GO:0006607 2 0.466
positive regulation of transcription factor import into nucleus GO:0042993 25 0.372
meiosis i GO:0007127 4 0.365
oogenesis GO:0048477 2 0.306
regulation of cell cycle phase transition GO:1901987 126 0.298
cell cycle phase transition GO:0044770 173 0.294
rna interference GO:0016246 4 0.287
nuclear division GO:0000280 128 0.278
mitotic cell cycle GO:0000278 326 0.270
purine ribonucleoside catabolic process GO:0046130 398 0.269
regulation of mitotic cell cycle phase transition GO:1901990 118 0.261
regulation of mitotic cell cycle GO:0007346 189 0.256
dna damage checkpoint GO:0000077 68 0.247
negative regulation of cell cycle GO:0045786 193 0.225
female gamete generation GO:0007292 2 0.211
cellular response to dna damage stimulus GO:0006974 379 0.195
embryo development GO:0009790 123 0.194
glycosyl compound catabolic process GO:1901658 413 0.193
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.177
mitotic cell cycle phase transition GO:0044772 162 0.160
post embryonic development GO:0009791 2 0.155
positive regulation of cellular amine metabolic process GO:0033240 7 0.154
negative regulation of mitotic cell cycle GO:0045930 102 0.140
response to oxidative stress GO:0006979 121 0.135
cell cycle checkpoint GO:0000075 117 0.132
regulation of transcription factor import into nucleus GO:0042990 39 0.131
response to abiotic stimulus GO:0009628 336 0.123
intracellular protein transport GO:0006886 270 0.114
amine metabolic process GO:0009308 44 0.111
nucleocytoplasmic transport GO:0006913 176 0.109
organelle fission GO:0048285 149 0.108
purine ribonucleoside metabolic process GO:0046128 437 0.105
regulation of intracellular protein transport GO:0033157 123 0.100
regulation of protein import into nucleus GO:0042306 78 0.099
mitotic cell cycle process GO:1903047 286 0.098
single organism cellular localization GO:1902580 332 0.096
cell morphogenesis GO:0000902 296 0.096
response to inorganic substance GO:0010035 127 0.091
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.088
mitotic cell cycle checkpoint GO:0007093 68 0.087
mitotic nuclear division GO:0007067 119 0.086
positive regulation of protein transport GO:0051222 135 0.081
organophosphate biosynthetic process GO:0090407 163 0.080
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.079
response to reactive oxygen species GO:0000302 61 0.076
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.076
response to uv GO:0009411 73 0.076
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.076
negative regulation of cell cycle process GO:0010948 121 0.075
digestive system development GO:0055123 75 0.073
positive regulation of intracellular protein transport GO:0090316 76 0.070
dna integrity checkpoint GO:0031570 71 0.064
protein localization to organelle GO:0033365 280 0.063
skin development GO:0043588 76 0.063
positive regulation of protein localization to nucleus GO:1900182 48 0.060
positive regulation of hydrolase activity GO:0051345 331 0.058
nucleoside phosphate catabolic process GO:1901292 412 0.054
regulation of cellular ketone metabolic process GO:0010565 50 0.054
associative learning GO:0008306 1 0.053
cell development GO:0048468 328 0.053
dna repair GO:0006281 198 0.052
gene silencing GO:0016458 49 0.052
cell projection organization GO:0030030 252 0.052
lipid metabolic process GO:0006629 381 0.051
response to radiation GO:0009314 151 0.051
protein targeting GO:0006605 187 0.051
actin filament based process GO:0030029 224 0.051
actin filament reorganization GO:0090527 1 0.051
glycerolipid metabolic process GO:0046486 107 0.049
plasma membrane organization GO:0007009 115 0.049
ribonucleoside triphosphate catabolic process GO:0009203 391 0.047
regulation of nucleocytoplasmic transport GO:0046822 98 0.047
establishment of protein localization to organelle GO:0072594 172 0.047
mitotic sister chromatid segregation GO:0000070 53 0.046
actin filament organization GO:0007015 128 0.046
nfat protein import into nucleus GO:0051531 5 0.046
purine nucleoside catabolic process GO:0006152 398 0.045
protein localization to nucleus GO:0034504 136 0.045
chromatin organization GO:0006325 351 0.045
regulation of mrna processing GO:0050684 48 0.044
positive regulation of cytoplasmic transport GO:1903651 82 0.043
epithelial cell proliferation GO:0050673 128 0.042
cellular amino acid metabolic process GO:0006520 116 0.042
transcription factor import into nucleus GO:0042991 40 0.042
g2 dna damage checkpoint GO:0031572 26 0.041
regulation of purine nucleotide metabolic process GO:1900542 264 0.041
ribonucleoside triphosphate metabolic process GO:0009199 412 0.041
cellular lipid metabolic process GO:0044255 303 0.039
negative regulation of cell cycle phase transition GO:1901988 89 0.039
regulation of gene expression epigenetic GO:0040029 73 0.039
mitotic dna damage checkpoint GO:0044773 28 0.039
posttranscriptional gene silencing by rna GO:0035194 25 0.039
regulation of nucleoside metabolic process GO:0009118 209 0.039
regulation of cytoplasmic transport GO:1903649 149 0.039
actin cytoskeleton organization GO:0030036 207 0.039
positive regulation of protein import into nucleus GO:0042307 46 0.038
epithelium development GO:0060429 227 0.037
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.037
posttranscriptional gene silencing GO:0016441 25 0.037
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
positive regulation of intracellular transport GO:0032388 104 0.036
response to light stimulus GO:0009416 87 0.036
positive regulation of cell development GO:0010720 92 0.036
mitotic dna integrity checkpoint GO:0044774 30 0.034
regulation of protein localization to nucleus GO:1900180 85 0.034
regulation of cell cycle process GO:0010564 266 0.034
ribonucleoside catabolic process GO:0042454 406 0.034
positive regulation of programmed cell death GO:0043068 249 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.033
purine nucleotide catabolic process GO:0006195 405 0.033
ribonucleoside monophosphate catabolic process GO:0009158 158 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
digestive tract morphogenesis GO:0048546 56 0.032
tissue morphogenesis GO:0048729 96 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
multicellular organism reproduction GO:0032504 42 0.031
regulation of protein localization GO:0032880 296 0.031
regulation of locomotion GO:0040012 329 0.031
regulation of proteolysis GO:0030162 293 0.031
regulation of cell differentiation GO:0045595 393 0.030
nuclear transport GO:0051169 179 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.030
positive regulation of transport GO:0051050 336 0.030
regulation of cell cycle GO:0051726 393 0.030
regulation of chromosome organization GO:0033044 103 0.030
calcium ion transmembrane transport GO:0070588 76 0.030
positive regulation of apoptotic process GO:0043065 246 0.029
regulation of cell morphogenesis GO:0022604 153 0.029
oocyte differentiation GO:0009994 2 0.029
regulation of actin filament based process GO:0032970 141 0.028
positive regulation of cell adhesion GO:0045785 84 0.028
somitogenesis GO:0001756 2 0.028
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.027
positive regulation of dendrite morphogenesis GO:0050775 3 0.027
regulation of cellular amine metabolic process GO:0033238 11 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
protein maturation GO:0051604 233 0.026
regulation of protein transport GO:0051223 213 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
protein targeting to nucleus GO:0044744 104 0.025
axon regeneration GO:0031103 1 0.025
cytoplasmic transport GO:0016482 379 0.025
chromatin modification GO:0016568 298 0.025
positive regulation of nucleoside metabolic process GO:0045979 186 0.025
small molecule biosynthetic process GO:0044283 157 0.024
regulation of epithelial cell proliferation GO:0050678 113 0.024
lipid biosynthetic process GO:0008610 177 0.024
glycerolipid biosynthetic process GO:0045017 51 0.024
regulation of protein targeting GO:1903533 91 0.024
protein polymerization GO:0051258 71 0.024
reproductive system development GO:0061458 56 0.024
vesicle mediated transport GO:0016192 371 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
cellular protein complex assembly GO:0043623 188 0.023
purine nucleoside monophosphate metabolic process GO:0009126 186 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
viral process GO:0016032 146 0.022
cellular ketone metabolic process GO:0042180 80 0.022
meiotic chromosome segregation GO:0045132 4 0.022
nucleoside monophosphate catabolic process GO:0009125 159 0.022
endocytosis GO:0006897 159 0.022
ribonucleotide catabolic process GO:0009261 405 0.021
nuclear pore organization GO:0006999 10 0.021
purine ribonucleotide biosynthetic process GO:0009152 79 0.021
single organism cell adhesion GO:0098602 179 0.020
cell adhesion GO:0007155 325 0.020
viral life cycle GO:0019058 132 0.020
single organism membrane organization GO:0044802 268 0.020
microtubule based process GO:0007017 210 0.020
meiotic cell cycle GO:0051321 13 0.020
blastocyst development GO:0001824 3 0.019
protein dna complex assembly GO:0065004 64 0.019
neuron development GO:0048666 113 0.019
single organism nuclear import GO:1902593 104 0.019
nucleoside triphosphate catabolic process GO:0009143 394 0.019
organophosphate catabolic process GO:0046434 430 0.019
positive regulation of cell differentiation GO:0045597 211 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
chordate embryonic development GO:0043009 34 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.018
secretion GO:0046903 254 0.018
alcohol metabolic process GO:0006066 114 0.018
neurogenesis GO:0022008 169 0.018
cell morphogenesis involved in differentiation GO:0000904 144 0.018
protein catabolic process GO:0030163 325 0.018
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.018
dna methylation or demethylation GO:0044728 19 0.018
nuclear import GO:0051170 106 0.018
interspecies interaction between organisms GO:0044419 156 0.018
angiogenesis GO:0001525 147 0.018
nucleoside catabolic process GO:0009164 408 0.018
regulation of transferase activity GO:0051338 355 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
peptidyl lysine acetylation GO:0018394 101 0.017
regulation of kinase activity GO:0043549 314 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
regulation of cell adhesion GO:0030155 166 0.017
response to hydrogen peroxide GO:0042542 40 0.017
glycerophospholipid metabolic process GO:0006650 84 0.017
intrinsic apoptotic signaling pathway GO:0097193 127 0.017
negative regulation of cell death GO:0060548 345 0.016
regulation of dna metabolic process GO:0051052 153 0.016
cytokinesis GO:0000910 96 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
regulation of atp metabolic process GO:1903578 29 0.016
double strand break repair GO:0006302 101 0.016
cellular component morphogenesis GO:0032989 314 0.016
nucleotide catabolic process GO:0009166 408 0.016
apoptotic signaling pathway GO:0097190 268 0.016
nucleosome assembly GO:0006334 50 0.016
regulation of cell migration GO:0030334 289 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
atp metabolic process GO:0046034 176 0.016
chromosome separation GO:0051304 23 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
embryonic morphogenesis GO:0048598 85 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
reproduction GO:0000003 63 0.015
ossification GO:0001503 121 0.015
protein autophosphorylation GO:0046777 123 0.015
ameboidal type cell migration GO:0001667 135 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
cell fate determination GO:0001709 3 0.015
histone modification GO:0016570 251 0.015
glycerophospholipid biosynthetic process GO:0046474 40 0.015
reproductive process GO:0022414 106 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
gastrulation GO:0007369 51 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
neuron differentiation GO:0030182 138 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
cell part morphogenesis GO:0032990 137 0.014
positive regulation of cell death GO:0010942 263 0.014
regulation of protein polymerization GO:0032271 63 0.014
replicative cell aging GO:0001302 3 0.014
dendrite development GO:0016358 24 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
actin filament bundle organization GO:0061572 54 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
regulation of cell motility GO:2000145 299 0.014
gonad development GO:0008406 34 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
positive regulation of rac gtpase activity GO:0032855 31 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
cellular amine metabolic process GO:0044106 41 0.014
regulation of cellular response to stress GO:0080135 244 0.014
cell division GO:0051301 168 0.014
biological adhesion GO:0022610 331 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
multi organism cellular process GO:0044764 156 0.013
cell projection assembly GO:0030031 126 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
cell aging GO:0007569 52 0.013
regulation of neurogenesis GO:0050767 82 0.013
lipoprotein metabolic process GO:0042157 42 0.013
potassium ion transport GO:0006813 62 0.013
organelle assembly GO:0070925 176 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.013
neuromuscular junction development GO:0007528 3 0.013
tissue migration GO:0090130 119 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
positive regulation of organelle organization GO:0010638 195 0.012
organic hydroxy compound biosynthetic process GO:1901617 71 0.012
activation of cysteine type endopeptidase activity GO:0097202 57 0.012
rna splicing via transesterification reactions GO:0000375 90 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
epidermis development GO:0008544 59 0.012
protein oligomerization GO:0051259 173 0.012
positive regulation of cytoskeleton organization GO:0051495 83 0.012
chromosome segregation GO:0007059 114 0.012
endothelial cell proliferation GO:0001935 65 0.012
dna conformation change GO:0071103 113 0.012
epidermal cell differentiation GO:0009913 45 0.012
regulation of protein complex assembly GO:0043254 147 0.012
response to starvation GO:0042594 59 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
nervous system development GO:0007399 293 0.012
dna recombination GO:0006310 77 0.011
regulation of cellular component size GO:0032535 82 0.011
microtubule based movement GO:0007018 32 0.011
segmentation GO:0035282 4 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
morphogenesis of an epithelium GO:0002009 60 0.011
mitotic g2 m transition checkpoint GO:0044818 9 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
multi organism reproductive process GO:0044703 54 0.011
rho protein signal transduction GO:0007266 26 0.011
regulation of cell cycle g1 s phase transition GO:1902806 42 0.011
negative regulation of transferase activity GO:0051348 124 0.011
mitotic g2 dna damage checkpoint GO:0007095 7 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
oocyte development GO:0048599 1 0.011
central nervous system development GO:0007417 123 0.011
ectodermal placode development GO:0071696 1 0.011
regulation of response to external stimulus GO:0032101 222 0.011
autophagy GO:0006914 88 0.011
protein acetylation GO:0006473 116 0.011
gland development GO:0048732 48 0.011
embryo development ending in birth or egg hatching GO:0009792 34 0.011
regulation of cellular component movement GO:0051270 334 0.011
generation of neurons GO:0048699 152 0.011
response to fungus GO:0009620 4 0.011
covalent chromatin modification GO:0016569 254 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
regulation of establishment of protein localization GO:0070201 242 0.010
gene silencing by rna GO:0031047 26 0.010
regulation of chromosome segregation GO:0051983 44 0.010
negative regulation of organelle organization GO:0010639 126 0.010
positive regulation of endopeptidase activity GO:0010950 84 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
centrosome organization GO:0051297 58 0.010
negative regulation of cellular protein metabolic process GO:0032269 353 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
developmental process involved in reproduction GO:0003006 66 0.010

RECQL disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
disease of metabolism DOID:0014667 295 0.013
inherited metabolic disorder DOID:655 242 0.013
organ system cancer DOID:0050686 164 0.012