Homo sapiens

71 known processes

MASTL

microtubule associated serine/threonine kinase-like

(Aliases: RP11-85G18.2,FLJ14813,THC2,GREATWALL,GWL)

MASTL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside triphosphate metabolic process GO:0009141 422 0.255
nucleoside phosphate catabolic process GO:1901292 412 0.236
purine ribonucleoside catabolic process GO:0046130 398 0.152
purine ribonucleotide catabolic process GO:0009154 404 0.149
purine ribonucleoside metabolic process GO:0046128 437 0.136
nucleotide catabolic process GO:0009166 408 0.120
glycosyl compound catabolic process GO:1901658 413 0.118
negative regulation of cell cycle phase transition GO:1901988 89 0.113
purine nucleoside catabolic process GO:0006152 398 0.112
purine containing compound catabolic process GO:0072523 411 0.112
ribonucleotide catabolic process GO:0009261 405 0.110
purine nucleotide catabolic process GO:0006195 405 0.108
nucleoside catabolic process GO:0009164 408 0.104
small gtpase mediated signal transduction GO:0007264 78 0.102
mitotic cell cycle process GO:1903047 286 0.100
regulation of cell cycle GO:0051726 393 0.096
ras protein signal transduction GO:0007265 73 0.095
ribonucleoside triphosphate metabolic process GO:0009199 412 0.093
chromatin organization GO:0006325 351 0.092
cell cycle checkpoint GO:0000075 117 0.087
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.086
negative regulation of cell cycle process GO:0010948 121 0.085
mitotic cell cycle phase transition GO:0044772 162 0.082
ribonucleoside catabolic process GO:0042454 406 0.082
ribonucleoside triphosphate catabolic process GO:0009203 391 0.079
regulation of cell cycle phase transition GO:1901987 126 0.078
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.077
regulation of dna metabolic process GO:0051052 153 0.077
regulation of chromosome segregation GO:0051983 44 0.074
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.073
regulation of protein catabolic process GO:0042176 155 0.073
negative regulation of cell cycle GO:0045786 193 0.072
mitotic cell cycle GO:0000278 326 0.070
microtubule organizing center organization GO:0031023 62 0.069
recombinational repair GO:0000725 50 0.069
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.068
protein catabolic process GO:0030163 325 0.068
regulation of cell cycle process GO:0010564 266 0.066
negative regulation of protein processing GO:0010955 142 0.061
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.061
purine nucleoside triphosphate metabolic process GO:0009144 412 0.060
regulation of purine nucleotide metabolic process GO:1900542 264 0.060
negative regulation of proteolysis GO:0045861 132 0.060
regulation of transferase activity GO:0051338 355 0.059
nuclear division GO:0000280 128 0.058
cytoplasmic transport GO:0016482 379 0.058
guanosine containing compound catabolic process GO:1901069 239 0.058
mitotic cell cycle checkpoint GO:0007093 68 0.057
guanosine containing compound metabolic process GO:1901068 244 0.056
negative regulation of cellular protein metabolic process GO:0032269 353 0.056
negative regulation of protein metabolic process GO:0051248 391 0.055
microtubule cytoskeleton organization GO:0000226 176 0.055
cellular macromolecule catabolic process GO:0044265 380 0.054
cellular response to oxidative stress GO:0034599 85 0.052
chromosome segregation GO:0007059 114 0.050
post embryonic development GO:0009791 2 0.050
regulation of mitotic cell cycle GO:0007346 189 0.050
regulation of proteolysis GO:0030162 293 0.049
negative regulation of mitotic cell cycle GO:0045930 102 0.048
mitotic nuclear division GO:0007067 119 0.047
protein processing GO:0016485 226 0.047
nucleoside triphosphate catabolic process GO:0009143 394 0.047
cell adhesion GO:0007155 325 0.046
cellular protein catabolic process GO:0044257 261 0.046
centrosome organization GO:0051297 58 0.045
purine nucleoside monophosphate metabolic process GO:0009126 186 0.045
regulation of protein processing GO:0070613 150 0.045
protein maturation GO:0051604 233 0.045
maintenance of location GO:0051235 112 0.045
regulation of mitotic cell cycle phase transition GO:1901990 118 0.045
cell cycle phase transition GO:0044770 173 0.044
nucleoside monophosphate metabolic process GO:0009123 191 0.044
negative regulation of catabolic process GO:0009895 104 0.043
negative regulation of organelle organization GO:0010639 126 0.043
regulation of nucleotide metabolic process GO:0006140 269 0.042
multicellular organismal aging GO:0010259 3 0.042
response to oxidative stress GO:0006979 121 0.042
regulation of microtubule cytoskeleton organization GO:0070507 61 0.041
regulation of protein maturation GO:1903317 150 0.041
purine nucleoside triphosphate catabolic process GO:0009146 392 0.041
mitotic sister chromatid segregation GO:0000070 53 0.040
cell fate determination GO:0001709 3 0.039
gtp metabolic process GO:0046039 239 0.039
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.039
negative regulation of cellular catabolic process GO:0031330 83 0.038
cell division GO:0051301 168 0.037
ubiquitin dependent protein catabolic process GO:0006511 206 0.036
female gamete generation GO:0007292 2 0.036
cellular response to dna damage stimulus GO:0006974 379 0.035
positive regulation of gtpase activity GO:0043547 166 0.035
regulation of small gtpase mediated signal transduction GO:0051056 156 0.035
regulation of protein kinase activity GO:0045859 289 0.034
regulation of chromosome organization GO:0033044 103 0.034
positive regulation of gtp catabolic process GO:0033126 166 0.034
regulation of nucleoside metabolic process GO:0009118 209 0.034
positive regulation of protein phosphorylation GO:0001934 313 0.034
negative regulation of chromosome organization GO:2001251 48 0.033
regulation of proteasomal protein catabolic process GO:0061136 87 0.033
positive regulation of catabolic process GO:0009896 310 0.033
chromatin modification GO:0016568 298 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.033
protein localization to organelle GO:0033365 280 0.033
purine nucleoside monophosphate catabolic process GO:0009128 158 0.033
regulation of microtubule based process GO:0032886 74 0.032
gtp catabolic process GO:0006184 237 0.032
embryo development GO:0009790 123 0.032
Worm
positive regulation of phosphorylation GO:0042327 394 0.031
regulation of ras protein signal transduction GO:0046578 155 0.031
protein autophosphorylation GO:0046777 123 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.031
nervous system development GO:0007399 293 0.031
meiotic chromosome segregation GO:0045132 4 0.031
organelle fission GO:0048285 149 0.031
regulation of kinase activity GO:0043549 314 0.031
rho protein signal transduction GO:0007266 26 0.030
sister chromatid segregation GO:0000819 54 0.030
anatomical structure formation involved in morphogenesis GO:0048646 284 0.030
proteasomal protein catabolic process GO:0010498 176 0.030
negative regulation of chromatin silencing GO:0031936 4 0.030
histone acetylation GO:0016573 93 0.030
intracellular protein transport GO:0006886 270 0.029
negative regulation of protein maturation GO:1903318 142 0.029
axoneme assembly GO:0035082 3 0.029
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
regulation of nucleotide catabolic process GO:0030811 205 0.029
regulation of protein serine threonine kinase activity GO:0071900 179 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.028
somatic stem cell division GO:0048103 1 0.028
response to abiotic stimulus GO:0009628 336 0.028
dna integrity checkpoint GO:0031570 71 0.028
regulation of cell differentiation GO:0045595 393 0.028
nucleoside monophosphate catabolic process GO:0009125 159 0.027
actin filament based process GO:0030029 224 0.027
cilium assembly GO:0042384 63 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
microtubule based process GO:0007017 210 0.027
dna repair GO:0006281 198 0.027
apoptotic signaling pathway GO:0097190 268 0.027
biological adhesion GO:0022610 331 0.027
centrosome cycle GO:0007098 32 0.027
regulation of cellular response to stress GO:0080135 244 0.026
rna processing GO:0006396 255 0.026
regulation of gtpase activity GO:0043087 180 0.026
cell projection organization GO:0030030 252 0.026
negative regulation of protein modification process GO:0031400 200 0.026
cellular component morphogenesis GO:0032989 314 0.026
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.025
double strand break repair GO:0006302 101 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
atp metabolic process GO:0046034 176 0.025
positive regulation of protein kinase activity GO:0045860 190 0.025
regulation of protein localization GO:0032880 296 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
positive regulation of kinase activity GO:0033674 204 0.025
determination of adult lifespan GO:0008340 2 0.025
positive regulation of nucleotide catabolic process GO:0030813 185 0.025
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
neuroblast proliferation GO:0007405 4 0.024
regulation of cellular protein catabolic process GO:1903362 96 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
negative regulation of cellular protein catabolic process GO:1903363 38 0.024
modification dependent macromolecule catabolic process GO:0043632 212 0.024
protein targeting GO:0006605 187 0.024
intrinsic apoptotic signaling pathway GO:0097193 127 0.024
negative regulation of protein catabolic process GO:0042177 59 0.024
internal peptidyl lysine acetylation GO:0018393 97 0.024
organelle assembly GO:0070925 176 0.023
regulation of mitotic sister chromatid segregation GO:0033047 27 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
positive regulation of organelle organization GO:0010638 195 0.023
stem cell division GO:0017145 2 0.023
regulation of dna replication GO:0006275 68 0.022
microtubule anchoring GO:0034453 24 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
cell morphogenesis GO:0000902 296 0.022
regulation of gtp catabolic process GO:0033124 180 0.022
positive regulation of apoptotic process GO:0043065 246 0.021
regulation of mapk cascade GO:0043408 262 0.021
double strand break repair via homologous recombination GO:0000724 50 0.021
maintenance of location in cell GO:0051651 62 0.021
internal protein amino acid acetylation GO:0006475 101 0.021
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.021
dna catabolic process GO:0006308 49 0.021
cellular amine metabolic process GO:0044106 41 0.021
dna conformation change GO:0071103 113 0.021
lipid metabolic process GO:0006629 381 0.021
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
amine metabolic process GO:0009308 44 0.020
positive regulation of transferase activity GO:0051347 227 0.020
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.020
centrosome duplication GO:0051298 28 0.020
positive regulation of mapk cascade GO:0043410 190 0.020
regulation of response to dna damage stimulus GO:2001020 94 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
actin filament based movement GO:0030048 17 0.019
cellular response to abiotic stimulus GO:0071214 117 0.019
chromosome separation GO:0051304 23 0.019
regulation of cell division GO:0051302 116 0.019
endomembrane system organization GO:0010256 196 0.019
dna recombination GO:0006310 77 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.019
dna catabolic process exonucleolytic GO:0000738 17 0.019
positive regulation of ras gtpase activity GO:0032320 117 0.019
protein modification by small protein conjugation GO:0032446 342 0.018
cell part morphogenesis GO:0032990 137 0.018
protein ubiquitination GO:0016567 314 0.018
blastocyst development GO:0001824 3 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
regulation of meiotic cell cycle GO:0051445 4 0.018
cellular ketone metabolic process GO:0042180 80 0.018
response to radiation GO:0009314 151 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
vesicle mediated transport GO:0016192 371 0.018
regulation of meiosis GO:0040020 3 0.017
cell cycle g2 m phase transition GO:0044839 43 0.017
regulation of protein transport GO:0051223 213 0.017
cellular amino acid metabolic process GO:0006520 116 0.017
negative regulation of developmental process GO:0051093 247 0.017
cell projection assembly GO:0030031 126 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
protein acylation GO:0043543 138 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
wnt signaling pathway GO:0016055 156 0.017
signal transduction by phosphorylation GO:0023014 297 0.016
single organism cellular localization GO:1902580 332 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
response to cytokine GO:0034097 232 0.016
cell development GO:0048468 328 0.016
peptidyl serine phosphorylation GO:0018105 101 0.016
regulation of cellular component movement GO:0051270 334 0.016
maintenance of protein location GO:0045185 57 0.016
positive regulation of cell cycle GO:0045787 140 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
generation of neurons GO:0048699 152 0.016
oogenesis GO:0048477 2 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
protein deubiquitination GO:0016579 79 0.016
histone modification GO:0016570 251 0.016
erythrocyte development GO:0048821 3 0.016
positive regulation of cell death GO:0010942 263 0.016
positive regulation of cell proliferation GO:0008284 301 0.015
regulation of locomotion GO:0040012 329 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
positive regulation of transport GO:0051050 336 0.015
asymmetric stem cell division GO:0098722 1 0.015
actin cytoskeleton organization GO:0030036 207 0.015
organophosphate catabolic process GO:0046434 430 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
regulation of response to external stimulus GO:0032101 222 0.015
epithelium development GO:0060429 227 0.015
regeneration GO:0031099 4 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
chromatin assembly GO:0031497 61 0.015
regulation of actin filament based process GO:0032970 141 0.014
cellular lipid metabolic process GO:0044255 303 0.014
mitotic sister chromatid separation GO:0051306 18 0.014
nuclear transport GO:0051169 179 0.014
peptidyl lysine acetylation GO:0018394 101 0.014
asymmetric neuroblast division GO:0055059 1 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
negative regulation of cell death GO:0060548 345 0.014
spindle checkpoint GO:0031577 26 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.014
hindbrain development GO:0030902 3 0.014
neuronal stem cell division GO:0036445 1 0.014
hemopoiesis GO:0030097 180 0.014
Zebrafish
organophosphate biosynthetic process GO:0090407 163 0.013
cellular response to radiation GO:0071478 65 0.013
anatomical structure homeostasis GO:0060249 100 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
oxidation reduction process GO:0055114 396 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
protein homooligomerization GO:0051260 100 0.013
mitochondrial transport GO:0006839 60 0.013
neuroblast division GO:0055057 1 0.013
maintenance of protein location in cell GO:0032507 56 0.013
regulation of intracellular transport GO:0032386 195 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
central nervous system development GO:0007417 123 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.013
defense response GO:0006952 315 0.013
meiosis i GO:0007127 4 0.013
protein import GO:0017038 130 0.013
cellular response to ionizing radiation GO:0071479 32 0.013
actin mediated cell contraction GO:0070252 12 0.013
peripheral nervous system development GO:0007422 2 0.013
regulation of nuclear division GO:0051783 65 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
mitotic dna integrity checkpoint GO:0044774 30 0.012
growth GO:0040007 202 0.012
oocyte maturation GO:0001556 1 0.012
regulation of dna repair GO:0006282 47 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.012
head development GO:0060322 108 0.012
neurogenesis GO:0022008 169 0.012
positive regulation of neural precursor cell proliferation GO:2000179 2 0.012
regulation of mitotic sister chromatid separation GO:0010965 27 0.012
positive regulation of dna replication GO:0045740 35 0.012
peptidyl serine modification GO:0018209 106 0.012
cdc42 protein signal transduction GO:0032488 4 0.012
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
mitochondrion organization GO:0007005 156 0.012
covalent chromatin modification GO:0016569 254 0.012
regulation of cell motility GO:2000145 299 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
muscle structure development GO:0061061 98 0.011
regulation of growth GO:0040008 165 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
ossification GO:0001503 121 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
brain development GO:0007420 97 0.011
regulation of chromatin organization GO:1902275 56 0.011
nitrogen compound transport GO:0071705 191 0.011
lipid biosynthetic process GO:0008610 177 0.011
protein acetylation GO:0006473 116 0.011
regulation of lipid metabolic process GO:0019216 96 0.011
sex determination GO:0007530 3 0.011
atp catabolic process GO:0006200 157 0.011
regulation of sister chromatid segregation GO:0033045 27 0.011
single organism reproductive process GO:0044702 98 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
neuron differentiation GO:0030182 138 0.011
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.011
cilium organization GO:0044782 68 0.011
response to ionizing radiation GO:0010212 65 0.011
cellular protein complex assembly GO:0043623 188 0.011
neurological system process GO:0050877 163 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
positive regulation of dna metabolic process GO:0051054 73 0.010
protein oligomerization GO:0051259 173 0.010
interspecies interaction between organisms GO:0044419 156 0.010
positive regulation of protein transport GO:0051222 135 0.010
response to wounding GO:0009611 168 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
nuclear import GO:0051170 106 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
single organism membrane organization GO:0044802 268 0.010
regulation of cell migration GO:0030334 289 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.010
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.010
reproduction GO:0000003 63 0.010
Worm
negative regulation of intracellular signal transduction GO:1902532 183 0.010
chromatin assembly or disassembly GO:0006333 78 0.010
erk1 and erk2 cascade GO:0070371 104 0.010
vasculature development GO:0001944 181 0.010
cell projection morphogenesis GO:0048858 129 0.010

MASTL disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.030
hematopoietic system disease DOID:74 100 0.025
disease of cellular proliferation DOID:14566 174 0.020
physical disorder DOID:0080015 41 0.012
cancer DOID:162 167 0.011
hemorrhagic disease DOID:2213 10 0.001
blood platelet disease DOID:2218 10 0.001
thrombocytopenia DOID:1588 5 0.001
blood coagulation disease DOID:1247 21 0.001