Homo sapiens

47 known processes

ALDH18A1

aldehyde dehydrogenase 18 family, member A1

(Aliases: P5CS,MGC117316,GSAS,PYCS)

ALDH18A1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleoside metabolic process GO:0046128 437 0.219
purine nucleoside triphosphate metabolic process GO:0009144 412 0.110
cellular amino acid metabolic process GO:0006520 116 0.099
nucleoside monophosphate metabolic process GO:0009123 191 0.099
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.098
purine containing compound catabolic process GO:0072523 411 0.092
carbohydrate metabolic process GO:0005975 207 0.087
ribonucleoside catabolic process GO:0042454 406 0.079
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.079
nucleoside triphosphate metabolic process GO:0009141 422 0.077
nucleoside triphosphate catabolic process GO:0009143 394 0.069
single organism carbohydrate metabolic process GO:0044723 193 0.066
nucleotide catabolic process GO:0009166 408 0.066
response to oxygen containing compound GO:1901700 369 0.065
ribonucleoside triphosphate metabolic process GO:0009199 412 0.063
purine nucleoside catabolic process GO:0006152 398 0.061
nucleoside catabolic process GO:0009164 408 0.060
determination of adult lifespan GO:0008340 2 0.058
ribonucleoside triphosphate catabolic process GO:0009203 391 0.057
purine ribonucleotide catabolic process GO:0009154 404 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.057
cellular component morphogenesis GO:0032989 314 0.053
organophosphate catabolic process GO:0046434 430 0.051
nucleoside phosphate catabolic process GO:1901292 412 0.049
cellular lipid metabolic process GO:0044255 303 0.047
inorganic ion transmembrane transport GO:0098660 231 0.045
atp metabolic process GO:0046034 176 0.044
positive regulation of programmed cell death GO:0043068 249 0.043
post embryonic development GO:0009791 2 0.042
carbohydrate derivative biosynthetic process GO:1901137 207 0.041
regulation of nucleoside metabolic process GO:0009118 209 0.041
protein glycosylation GO:0006486 62 0.040
purine ribonucleoside catabolic process GO:0046130 398 0.040
glycosylation GO:0070085 71 0.039
oogenesis GO:0048477 2 0.039
guanosine containing compound catabolic process GO:1901069 239 0.039
glycoprotein metabolic process GO:0009100 110 0.039
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
regulation of cell development GO:0060284 161 0.038
mitochondrion organization GO:0007005 156 0.037
positive regulation of immune system process GO:0002684 283 0.037
negative regulation of catalytic activity GO:0043086 335 0.037
transmembrane transport GO:0055085 399 0.037
negative regulation of protein metabolic process GO:0051248 391 0.035
chemical homeostasis GO:0048878 306 0.035
ribonucleotide catabolic process GO:0009261 405 0.034
glycosyl compound catabolic process GO:1901658 413 0.034
apoptotic signaling pathway GO:0097190 268 0.034
positive regulation of cell death GO:0010942 263 0.033
regulation of purine nucleotide metabolic process GO:1900542 264 0.033
nitrogen compound transport GO:0071705 191 0.033
system process GO:0003008 349 0.033
negative regulation of apoptotic process GO:0043066 316 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.031
multicellular organismal aging GO:0010259 3 0.031
cation transport GO:0006812 331 0.030
ion homeostasis GO:0050801 230 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.030
positive regulation of developmental process GO:0051094 314 0.030
vesicle mediated transport GO:0016192 371 0.029
regulation of gtp catabolic process GO:0033124 180 0.029
nucleotide biosynthetic process GO:0009165 109 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.028
female gamete generation GO:0007292 2 0.028
response to abiotic stimulus GO:0009628 336 0.028
negative regulation of cell death GO:0060548 345 0.028
cation transmembrane transport GO:0098655 238 0.028
ribonucleoside monophosphate catabolic process GO:0009158 158 0.027
cytoplasmic transport GO:0016482 379 0.027
cellular response to nitrogen compound GO:1901699 144 0.027
endocytosis GO:0006897 159 0.027
purine nucleoside monophosphate metabolic process GO:0009126 186 0.027
mitochondrial rna metabolic process GO:0000959 15 0.027
regulation of proteolysis GO:0030162 293 0.026
locomotory behavior GO:0007626 1 0.026
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
gtp metabolic process GO:0046039 239 0.026
cell morphogenesis GO:0000902 296 0.026
glycoprotein biosynthetic process GO:0009101 91 0.026
purine nucleotide catabolic process GO:0006195 405 0.025
nucleoside monophosphate catabolic process GO:0009125 159 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
secretion GO:0046903 254 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
protein maturation GO:0051604 233 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
protein processing GO:0016485 226 0.024
regulation of nucleotide catabolic process GO:0030811 205 0.024
cellular cation homeostasis GO:0030003 163 0.024
gtp catabolic process GO:0006184 237 0.024
cell part morphogenesis GO:0032990 137 0.024
endomembrane system organization GO:0010256 196 0.023
regulation of growth GO:0040008 165 0.023
ion transmembrane transport GO:0034220 338 0.023
regulation of gtpase activity GO:0043087 180 0.023
macromolecule glycosylation GO:0043413 63 0.022
cofactor metabolic process GO:0051186 87 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
protein catabolic process GO:0030163 325 0.022
regulation of cell differentiation GO:0045595 393 0.022
positive regulation of apoptotic process GO:0043065 246 0.022
metal ion transport GO:0030001 272 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
cellular modified amino acid metabolic process GO:0006575 64 0.021
cellular homeostasis GO:0019725 196 0.021
immune response GO:0006955 307 0.020
inorganic cation transmembrane transport GO:0098662 194 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
regulation of peptidase activity GO:0052547 180 0.019
positive regulation of catabolic process GO:0009896 310 0.019
neurological system process GO:0050877 163 0.019
cellular ketone metabolic process GO:0042180 80 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
hindbrain development GO:0030902 3 0.019
lipid metabolic process GO:0006629 381 0.019
regeneration GO:0031099 4 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
neuromuscular junction development GO:0007528 3 0.019
ribose phosphate biosynthetic process GO:0046390 82 0.019
cytokine production GO:0001816 247 0.018
cellular response to oxidative stress GO:0034599 85 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
translation GO:0006412 132 0.018
growth GO:0040007 202 0.018
ras protein signal transduction GO:0007265 73 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
regulation of protein processing GO:0070613 150 0.017
cation homeostasis GO:0055080 189 0.017
cellular protein catabolic process GO:0044257 261 0.017
cell projection organization GO:0030030 252 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
amine metabolic process GO:0009308 44 0.017
response to other organism GO:0051707 261 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.016
negative regulation of protein maturation GO:1903318 142 0.016
negative regulation of programmed cell death GO:0043069 321 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
carboxylic acid biosynthetic process GO:0046394 97 0.016
cilium morphogenesis GO:0060271 75 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
chromatin modification GO:0016568 298 0.016
secretion by cell GO:0032940 226 0.016
defense response GO:0006952 315 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
spermatid differentiation GO:0048515 4 0.016
single organism membrane organization GO:0044802 268 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
oxidation reduction process GO:0055114 396 0.015
response to external biotic stimulus GO:0043207 261 0.015
regulation of transferase activity GO:0051338 355 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
single organism cellular localization GO:1902580 332 0.015
cellular amine metabolic process GO:0044106 41 0.015
atp catabolic process GO:0006200 157 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
regulation of cellular component biogenesis GO:0044087 281 0.014
lipid biosynthetic process GO:0008610 177 0.014
divalent inorganic cation homeostasis GO:0072507 136 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
spermatid development GO:0007286 4 0.014
sulfur compound metabolic process GO:0006790 101 0.014
regulation of cell projection organization GO:0031344 107 0.014
regulation of kinase activity GO:0043549 314 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
single organism reproductive process GO:0044702 98 0.014
anterior posterior axis specification GO:0009948 2 0.014
purine containing compound biosynthetic process GO:0072522 88 0.014
mitotic cell cycle GO:0000278 326 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
segmentation GO:0035282 4 0.014
cellular ion homeostasis GO:0006873 168 0.014
regulation of cellular response to stress GO:0080135 244 0.013
cellular chemical homeostasis GO:0055082 180 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
regulation of cell cycle process GO:0010564 266 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.013
negative regulation of proteolysis GO:0045861 132 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
regulation of multi organism process GO:0043900 157 0.013
mitotic cell cycle process GO:1903047 286 0.013
organic acid biosynthetic process GO:0016053 97 0.013
regulation of protein maturation GO:1903317 150 0.013
sensory perception GO:0007600 103 0.013
protein localization to organelle GO:0033365 280 0.013
compound eye development GO:0048749 1 0.013
alpha amino acid metabolic process GO:1901605 72 0.013
glycerolipid metabolic process GO:0046486 107 0.013
divalent inorganic cation transport GO:0072511 158 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
organ morphogenesis GO:0009887 147 0.012
regulation of response to external stimulus GO:0032101 222 0.012
response to biotic stimulus GO:0009607 276 0.012
negative regulation of protein processing GO:0010955 142 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
regulation of protein transport GO:0051223 213 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
organic acid catabolic process GO:0016054 71 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
dna repair GO:0006281 198 0.012
cellular response to hormone stimulus GO:0032870 125 0.012
cell growth GO:0016049 160 0.012
protein oligomerization GO:0051259 173 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
positive regulation of immune response GO:0050778 159 0.011
epithelium development GO:0060429 227 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
regulation of defense response GO:0031347 154 0.011
protein n linked glycosylation GO:0006487 23 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
coenzyme metabolic process GO:0006732 65 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.011
regulation of cell motility GO:2000145 299 0.011
immune system development GO:0002520 195 0.011
actin filament based process GO:0030029 224 0.011
regulation of protein catabolic process GO:0042176 155 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
regulation of immune response GO:0050776 201 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
embryo development GO:0009790 123 0.011
regulation of protein localization GO:0032880 296 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
regulation of cell adhesion GO:0030155 166 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
response to bacterium GO:0009617 144 0.011
cell development GO:0048468 328 0.011
regulation of locomotion GO:0040012 329 0.011
negative regulation of multi organism process GO:0043901 92 0.011
regulation of cellular component movement GO:0051270 334 0.011
divalent metal ion transport GO:0070838 152 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
regulation of cell cycle GO:0051726 393 0.011
adult locomotory behavior GO:0008344 1 0.011
protein targeting GO:0006605 187 0.011
organelle assembly GO:0070925 176 0.011
regulation of neurogenesis GO:0050767 82 0.011
metal ion homeostasis GO:0055065 169 0.010
regulation of protein kinase activity GO:0045859 289 0.010
negative regulation of growth GO:0045926 97 0.010
response to virus GO:0009615 126 0.010
innate immune response GO:0045087 178 0.010
leukocyte activation GO:0045321 164 0.010
developmental programmed cell death GO:0010623 3 0.010

ALDH18A1 disease predictions

Disease DO term ID Size Probability Func Analog Org
joubert syndrome DOID:0050777 18 0.088
disease of metabolism DOID:0014667 295 0.065
inherited metabolic disorder DOID:655 242 0.065
amino acid metabolic disorder DOID:9252 50 0.030
carbohydrate metabolic disorder DOID:2978 55 0.029
congenital disorder of glycosylation DOID:5212 26 0.029
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
congenital disorder of glycosylation type i DOID:0050570 16 0.013
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.011
neuropathy DOID:870 52 0.010