Homo sapiens

25 known processes

TSEN54

tRNA splicing endonuclease 54 homolog (S. cerevisiae)

(Aliases: FLJ37147,sen54,PCH4,SEN54L,PCH2A)

TSEN54 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.089
amine metabolic process GO:0009308 44 0.074
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.059
multicellular organismal aging GO:0010259 3 0.058
regulation of cellular amine metabolic process GO:0033238 11 0.055
post embryonic development GO:0009791 2 0.049
locomotory behavior GO:0007626 1 0.049
regulation of cellular ketone metabolic process GO:0010565 50 0.049
regulation of cellular amino acid metabolic process GO:0006521 6 0.049
cellular amine metabolic process GO:0044106 41 0.047
mating GO:0007618 1 0.046
female gamete generation GO:0007292 2 0.046
organelle assembly GO:0070925 176 0.044
regulation of proteolysis GO:0030162 293 0.044
cellular ketone metabolic process GO:0042180 80 0.043
chemical homeostasis GO:0048878 306 0.042
segmentation GO:0035282 4 0.042
negative regulation of cell cycle GO:0045786 193 0.042
oogenesis GO:0048477 2 0.042
nervous system development GO:0007399 293 0.040
cellular response to dna damage stimulus GO:0006974 379 0.040
hindbrain development GO:0030902 3 0.038
mitotic cell cycle process GO:1903047 286 0.038
determination of adult lifespan GO:0008340 2 0.038
circadian behavior GO:0048512 2 0.038
cell development GO:0048468 328 0.037
actin filament based process GO:0030029 224 0.036
posttranscriptional regulation of gene expression GO:0010608 213 0.034
positive regulation of cellular amine metabolic process GO:0033240 7 0.034
chromatin organization GO:0006325 351 0.034
protein catabolic process GO:0030163 325 0.033
inorganic ion transmembrane transport GO:0098660 231 0.033
negative regulation of catalytic activity GO:0043086 335 0.032
negative regulation of cell death GO:0060548 345 0.032
compound eye development GO:0048749 1 0.031
cellular component morphogenesis GO:0032989 314 0.031
cell morphogenesis GO:0000902 296 0.031
chromatin modification GO:0016568 298 0.031
rna interference GO:0016246 4 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
protein modification by small protein conjugation GO:0032446 342 0.030
protein ubiquitination GO:0016567 314 0.030
trna processing GO:0008033 23 0.029
single organism membrane organization GO:0044802 268 0.029
anatomical structure formation involved in morphogenesis GO:0048646 284 0.029
cellular component assembly involved in morphogenesis GO:0010927 73 0.029
regulation of cell cycle GO:0051726 393 0.028
sex determination GO:0007530 3 0.028
positive regulation of phosphorylation GO:0042327 394 0.028
memory GO:0007613 3 0.027
enzyme linked receptor protein signaling pathway GO:0007167 303 0.026
transmembrane transport GO:0055085 399 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
dephosphorylation GO:0016311 209 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
regulation of kinase activity GO:0043549 314 0.024
mitotic cell cycle GO:0000278 326 0.024
cell projection organization GO:0030030 252 0.024
negative regulation of programmed cell death GO:0043069 321 0.024
regulation of transferase activity GO:0051338 355 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
membrane organization GO:0061024 292 0.023
regulation of endopeptidase activity GO:0052548 170 0.023
single organism cellular localization GO:1902580 332 0.022
cation transport GO:0006812 331 0.022
ras protein signal transduction GO:0007265 73 0.022
oocyte differentiation GO:0009994 2 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
neuromuscular junction development GO:0007528 3 0.022
regulation of peptidase activity GO:0052547 180 0.022
response to abiotic stimulus GO:0009628 336 0.021
neurogenesis GO:0022008 169 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
system process GO:0003008 349 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
covalent chromatin modification GO:0016569 254 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
ncrna processing GO:0034470 83 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
microtubule based process GO:0007017 210 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
response to growth factor GO:0070848 205 0.020
ubiquitin dependent protein catabolic process GO:0006511 206 0.020
metencephalon development GO:0022037 2 0.020
protein processing GO:0016485 226 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
positive regulation of cell death GO:0010942 263 0.019
myosin filament assembly GO:0031034 2 0.019
oocyte development GO:0048599 1 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
eye photoreceptor cell differentiation GO:0001754 2 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.019
apoptotic signaling pathway GO:0097190 268 0.019
blastoderm segmentation GO:0007350 2 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
regulation of locomotion GO:0040012 329 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
regulation of cellular response to stress GO:0080135 244 0.018
vesicle mediated transport GO:0016192 371 0.018
dna repair GO:0006281 198 0.018
mitotic nuclear division GO:0007067 119 0.018
negative regulation of mitotic cell cycle GO:0045930 102 0.018
negative regulation of protein maturation GO:1903318 142 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
regulation of protein catabolic process GO:0042176 155 0.018
regulation of establishment of protein localization GO:0070201 242 0.017
cell cycle phase transition GO:0044770 173 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
maintenance of location GO:0051235 112 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
neuron differentiation GO:0030182 138 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
negative regulation of protein modification process GO:0031400 200 0.017
nuclear division GO:0000280 128 0.017
cellular homeostasis GO:0019725 196 0.017
regulation of protein localization GO:0032880 296 0.017
growth GO:0040007 202 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
regulation of cell cycle process GO:0010564 266 0.016
regulation of response to external stimulus GO:0032101 222 0.016
regulation of protein kinase activity GO:0045859 289 0.016
behavior GO:0007610 112 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
positive regulation of catabolic process GO:0009896 310 0.016
positive regulation of transport GO:0051050 336 0.016
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.016
rhythmic behavior GO:0007622 2 0.016
divalent metal ion transport GO:0070838 152 0.016
cellular protein catabolic process GO:0044257 261 0.016
meiosis i GO:0007127 4 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
ion transmembrane transport GO:0034220 338 0.016
rna processing GO:0006396 255 0.015
long term memory GO:0007616 2 0.015
microtubule organizing center organization GO:0031023 62 0.015
positive regulation of hydrolase activity GO:0051345 331 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
generation of neurons GO:0048699 152 0.015
cell division GO:0051301 168 0.015
positive regulation of transferase activity GO:0051347 227 0.015
anion transport GO:0006820 161 0.015
cytoplasmic transport GO:0016482 379 0.015
regulation of protein transport GO:0051223 213 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
secretion by cell GO:0032940 226 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
organophosphate catabolic process GO:0046434 430 0.014
protein autophosphorylation GO:0046777 123 0.014
trna metabolic process GO:0006399 35 0.014
somatic muscle development GO:0007525 1 0.014
protein complex disassembly GO:0043241 52 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
intracellular mrna localization GO:0008298 1 0.014
nitrogen compound transport GO:0071705 191 0.014
regulation of mapk cascade GO:0043408 262 0.014
erk1 and erk2 cascade GO:0070371 104 0.014
mapk cascade GO:0000165 288 0.014
regulation of secretion GO:0051046 194 0.014
nucleotide catabolic process GO:0009166 408 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
cytokine mediated signaling pathway GO:0019221 109 0.014
negative regulation of protein processing GO:0010955 142 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
peptidyl lysine modification GO:0018205 144 0.014
anterior posterior axis specification GO:0009948 2 0.014
metal ion transport GO:0030001 272 0.014
myosin filament organization GO:0031033 2 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
response to fungus GO:0009620 4 0.013
meiotic chromosome segregation GO:0045132 4 0.013
cellular response to abiotic stimulus GO:0071214 117 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
cell growth GO:0016049 160 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
positive regulation of cytoskeleton organization GO:0051495 83 0.013
chemotaxis GO:0006935 157 0.013
cell cell signaling GO:0007267 155 0.013
organic anion transport GO:0015711 103 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
regulation of cell migration GO:0030334 289 0.013
cell projection morphogenesis GO:0048858 129 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.013
taxis GO:0042330 157 0.013
adult locomotory behavior GO:0008344 1 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
tissue morphogenesis GO:0048729 96 0.013
regulation of protein stability GO:0031647 87 0.013
regulation of secretion by cell GO:1903530 177 0.013
macromolecular complex disassembly GO:0032984 60 0.013
regulation of protein processing GO:0070613 150 0.013
response to radiation GO:0009314 151 0.013
regulation of dna metabolic process GO:0051052 153 0.012
spermatid differentiation GO:0048515 4 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
mitotic sister chromatid segregation GO:0000070 53 0.012
negative regulation of proteolysis GO:0045861 132 0.012
cell morphogenesis involved in differentiation GO:0000904 144 0.012
regulation of gene expression epigenetic GO:0040029 73 0.012
cellular response to oxidative stress GO:0034599 85 0.012
protein polyubiquitination GO:0000209 110 0.012
striated muscle myosin thick filament assembly GO:0071688 2 0.012
glial cell migration GO:0008347 4 0.012
chromosome segregation GO:0007059 114 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
spermatid development GO:0007286 4 0.012
carbohydrate metabolic process GO:0005975 207 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
plasma membrane organization GO:0007009 115 0.012
organ morphogenesis GO:0009887 147 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
regulation of growth GO:0040008 165 0.012
positive regulation of organelle organization GO:0010638 195 0.012
neuron development GO:0048666 113 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
cell fate determination GO:0001709 3 0.012
mitochondrion organization GO:0007005 156 0.012
inorganic cation transmembrane transport GO:0098662 194 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
regulation of protein maturation GO:1903317 150 0.011
secretion GO:0046903 254 0.011
lipid metabolic process GO:0006629 381 0.011
central nervous system development GO:0007417 123 0.011
protein acylation GO:0043543 138 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
epithelium development GO:0060429 227 0.011
inner ear morphogenesis GO:0042472 4 0.011
regulation of cellular response to growth factor stimulus GO:0090287 76 0.011
neurological system process GO:0050877 163 0.011
cell projection assembly GO:0030031 126 0.011
protein localization to membrane GO:0072657 160 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
regulation of cell motility GO:2000145 299 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
ribonucleoprotein complex subunit organization GO:0071826 81 0.011
apoptotic mitochondrial changes GO:0008637 57 0.011
cellular protein complex assembly GO:0043623 188 0.011
regulation of glial cell differentiation GO:0045685 3 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
response to oxidative stress GO:0006979 121 0.011
response to external biotic stimulus GO:0043207 261 0.010
cellular component disassembly GO:0022411 92 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.010
response to nitrogen compound GO:1901698 184 0.010
anterior posterior axis specification embryo GO:0008595 2 0.010
aortic valve development GO:0003176 3 0.010
intracellular protein transport GO:0006886 270 0.010
cell part morphogenesis GO:0032990 137 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010
cellular lipid metabolic process GO:0044255 303 0.010
neural tube formation GO:0001841 3 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
response to oxygen containing compound GO:1901700 369 0.010
protein maturation GO:0051604 233 0.010
tripartite regional subdivision GO:0007351 2 0.010
regulation of actin filament based process GO:0032970 141 0.010
morphogenesis of embryonic epithelium GO:0016331 4 0.010
head development GO:0060322 108 0.010
regulation of cellular component movement GO:0051270 334 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.010
reproductive process GO:0022414 106 0.010
regulation of protein complex assembly GO:0043254 147 0.010
negative regulation of endopeptidase activity GO:0010951 84 0.010

TSEN54 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.038
disease of cellular proliferation DOID:14566 174 0.038
organ system cancer DOID:0050686 164 0.026
disease of metabolism DOID:0014667 295 0.022
musculoskeletal system disease DOID:17 223 0.019
central nervous system disease DOID:331 186 0.016
nervous system disease DOID:863 431 0.016
inherited metabolic disorder DOID:655 242 0.015
brain disease DOID:936 73 0.012
gastrointestinal system cancer DOID:3119 52 0.012
muscular disease DOID:0080000 114 0.011