Homo sapiens

73 known processes

LEMD3

LEM domain containing 3

(Aliases: MAN1)

LEMD3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 371 0.123
determination of adult lifespan GO:0008340 2 0.117
multicellular organismal aging GO:0010259 3 0.112
response to oxygen containing compound GO:1901700 369 0.106
cytoplasmic transport GO:0016482 379 0.103
response to biotic stimulus GO:0009607 276 0.101
cellular component morphogenesis GO:0032989 314 0.099
cellular amino acid metabolic process GO:0006520 116 0.090
protein catabolic process GO:0030163 325 0.082
response to external biotic stimulus GO:0043207 261 0.078
post embryonic development GO:0009791 2 0.072
cation transport GO:0006812 331 0.068
response to other organism GO:0051707 261 0.067
regulation of cellular component biogenesis GO:0044087 281 0.065
cellular ketone metabolic process GO:0042180 80 0.065
metal ion transport GO:0030001 272 0.062
enzyme linked receptor protein signaling pathway GO:0007167 303 0.062
regulation of cellular amino acid metabolic process GO:0006521 6 0.060
secretion GO:0046903 254 0.057
defense response GO:0006952 315 0.055
stem cell division GO:0017145 2 0.054
transmembrane transport GO:0055085 399 0.053
protein ubiquitination GO:0016567 314 0.051
system process GO:0003008 349 0.051
regulation of intracellular transport GO:0032386 195 0.050
negative regulation of phosphorylation GO:0042326 174 0.050
regulation of cytoplasmic transport GO:1903649 149 0.050
negative regulation of catalytic activity GO:0043086 335 0.048
neuromuscular junction development GO:0007528 3 0.048
inorganic cation transmembrane transport GO:0098662 194 0.046
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.046
negative regulation of phosphate metabolic process GO:0045936 267 0.046
oogenesis GO:0048477 2 0.045
negative regulation of programmed cell death GO:0043069 321 0.044
cellular lipid metabolic process GO:0044255 303 0.044
positive regulation of cellular component organization GO:0051130 376 0.043
cell morphogenesis GO:0000902 296 0.042
ion transmembrane transport GO:0034220 338 0.042
single organism cellular localization GO:1902580 332 0.041
actin filament based process GO:0030029 224 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.040
negative regulation of cell death GO:0060548 345 0.039
negative regulation of cellular component organization GO:0051129 235 0.038
ubiquitin dependent protein catabolic process GO:0006511 206 0.038
response to growth factor GO:0070848 205 0.038
regulation of mapk cascade GO:0043408 262 0.038
nucleoside catabolic process GO:0009164 408 0.038
protein localization to organelle GO:0033365 280 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.038
mitotic cell cycle GO:0000278 326 0.037
negative regulation of apoptotic process GO:0043066 316 0.037
rna processing GO:0006396 255 0.036
negative regulation of protein metabolic process GO:0051248 391 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
positive regulation of cellular amine metabolic process GO:0033240 7 0.036
cation transmembrane transport GO:0098655 238 0.035
mitotic cell cycle process GO:1903047 286 0.035
regulation of meiotic cell cycle GO:0051445 4 0.035
positive regulation of intracellular transport GO:0032388 104 0.035
maintenance of location GO:0051235 112 0.034
positive regulation of catabolic process GO:0009896 310 0.034
cellular amine metabolic process GO:0044106 41 0.034
positive regulation of programmed cell death GO:0043068 249 0.033
cell projection organization GO:0030030 252 0.033
regulation of transferase activity GO:0051338 355 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.033
positive regulation of transport GO:0051050 336 0.032
modification dependent macromolecule catabolic process GO:0043632 212 0.032
axis elongation GO:0003401 4 0.032
establishment of protein localization to organelle GO:0072594 172 0.032
organophosphate catabolic process GO:0046434 430 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
chemical homeostasis GO:0048878 306 0.031
regulation of protein localization GO:0032880 296 0.031
regulation of establishment of protein localization GO:0070201 242 0.031
positive regulation of cytoplasmic transport GO:1903651 82 0.031
protein modification by small protein conjugation GO:0032446 342 0.030
intracellular protein transport GO:0006886 270 0.030
nuclear import GO:0051170 106 0.030
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.029
apoptotic signaling pathway GO:0097190 268 0.029
cellular macromolecular complex assembly GO:0034622 324 0.029
regulation of growth GO:0040008 165 0.029
behavioral response to ethanol GO:0048149 2 0.029
response to abiotic stimulus GO:0009628 336 0.029
protein targeting GO:0006605 187 0.029
signal transduction by phosphorylation GO:0023014 297 0.029
morphogenesis of embryonic epithelium GO:0016331 4 0.029
regulation of protein transport GO:0051223 213 0.028
purine containing compound catabolic process GO:0072523 411 0.028
regulation of protein kinase activity GO:0045859 289 0.028
amine metabolic process GO:0009308 44 0.028
nuclear transport GO:0051169 179 0.028
dephosphorylation GO:0016311 209 0.028
regulation of kinase activity GO:0043549 314 0.028
lipid biosynthetic process GO:0008610 177 0.028
ribonucleotide catabolic process GO:0009261 405 0.028
inorganic ion transmembrane transport GO:0098660 231 0.027
cell cycle phase transition GO:0044770 173 0.027
defense response to other organism GO:0098542 129 0.027
mapk cascade GO:0000165 288 0.027
positive regulation of cell death GO:0010942 263 0.027
cell development GO:0048468 328 0.027
carboxylic acid biosynthetic process GO:0046394 97 0.026
negative regulation of cell growth GO:0030308 83 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
negative regulation of transport GO:0051051 176 0.026
female gamete generation GO:0007292 2 0.026
regulation of cell morphogenesis GO:0022604 153 0.026
regulation of protein ubiquitination GO:0031396 95 0.026
internal protein amino acid acetylation GO:0006475 101 0.026
chemotaxis GO:0006935 157 0.025
regulation of nucleocytoplasmic transport GO:0046822 98 0.025
negative regulation of protein transport GO:0051224 75 0.025
response to radiation GO:0009314 151 0.025
multi organism cellular process GO:0044764 156 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
nucleocytoplasmic transport GO:0006913 176 0.025
regulation of vesicle mediated transport GO:0060627 130 0.025
guanosine containing compound catabolic process GO:1901069 239 0.025
negative regulation of cell proliferation GO:0008285 228 0.025
biological adhesion GO:0022610 331 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
cellular protein catabolic process GO:0044257 261 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.024
carbohydrate metabolic process GO:0005975 207 0.024
regulation of defense response GO:0031347 154 0.024
proteasomal protein catabolic process GO:0010498 176 0.024
cell morphogenesis involved in differentiation GO:0000904 144 0.024
negative regulation of protein modification process GO:0031400 200 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
cellular macromolecule catabolic process GO:0044265 380 0.023
fatty acid biosynthetic process GO:0006633 46 0.023
protein localization to nucleus GO:0034504 136 0.023
neuron development GO:0048666 113 0.023
nervous system development GO:0007399 293 0.023
maintenance of protein location GO:0045185 57 0.023
small molecule biosynthetic process GO:0044283 157 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
potassium ion transport GO:0006813 62 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
ribosomal large subunit export from nucleus GO:0000055 3 0.022
wnt signaling pathway GO:0016055 156 0.022
positive regulation of protein transport GO:0051222 135 0.022
secretion by cell GO:0032940 226 0.022
lipid metabolic process GO:0006629 381 0.022
internal peptidyl lysine acetylation GO:0018393 97 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
organic hydroxy compound metabolic process GO:1901615 147 0.022
protein targeting to nucleus GO:0044744 104 0.021
regulation of protein import into nucleus GO:0042306 78 0.021
segmentation GO:0035282 4 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
developmental growth GO:0048589 48 0.021
primary neural tube formation GO:0014020 3 0.021
negative regulation of apoptotic signaling pathway GO:2001234 97 0.021
cell growth GO:0016049 160 0.021
central nervous system development GO:0007417 123 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
modification dependent protein catabolic process GO:0019941 209 0.021
tube closure GO:0060606 3 0.020
protein oligomerization GO:0051259 173 0.020
immune response GO:0006955 307 0.020
cell adhesion GO:0007155 325 0.020
neurotransmitter secretion GO:0007269 4 0.020
cell fate determination GO:0001709 3 0.020
negative regulation of cell cycle GO:0045786 193 0.020
hindbrain development GO:0030902 3 0.020
regulation of mrna export from nucleus GO:0010793 3 0.020
regulation of protein catabolic process GO:0042176 155 0.020
nucleotide catabolic process GO:0009166 408 0.020
cell part morphogenesis GO:0032990 137 0.020
growth GO:0040007 202 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
ribonucleoprotein complex biogenesis GO:0022613 116 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.019
vesicle organization GO:0016050 62 0.019
cell projection morphogenesis GO:0048858 129 0.019
protein dephosphorylation GO:0006470 81 0.019
regulation of cell cycle GO:0051726 393 0.019
Mouse
nitrogen compound transport GO:0071705 191 0.019
endocytosis GO:0006897 159 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.018
cell cell signaling GO:0007267 155 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
cellular response to endogenous stimulus GO:0071495 336 0.018
positive regulation of endopeptidase activity GO:0010950 84 0.018
regulation of multi organism process GO:0043900 157 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
negative regulation of protein phosphorylation GO:0001933 140 0.018
alcohol metabolic process GO:0006066 114 0.018
protein acylation GO:0043543 138 0.018
protein import into nucleus GO:0006606 104 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
endosomal transport GO:0016197 129 0.018
chromatin organization GO:0006325 351 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
peptidyl lysine modification GO:0018205 144 0.017
histone acetylation GO:0016573 93 0.017
single organism nuclear import GO:1902593 104 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
ion homeostasis GO:0050801 230 0.017
maintenance of location in cell GO:0051651 62 0.017
positive regulation of developmental process GO:0051094 314 0.017
ras protein signal transduction GO:0007265 73 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
steroid metabolic process GO:0008202 94 0.017
regulation of cell cycle process GO:0010564 266 0.017
glycerolipid metabolic process GO:0046486 107 0.017
innate immune response GO:0045087 178 0.017
regulation of proteolysis GO:0030162 293 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
negative regulation of kinase activity GO:0033673 106 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
purine nucleotide catabolic process GO:0006195 405 0.016
convergent extension GO:0060026 1 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.016
positive regulation of proteolysis GO:0045862 142 0.016
negative regulation of cell differentiation GO:0045596 171 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
response to organic cyclic compound GO:0014070 204 0.015
ribonucleoprotein complex assembly GO:0022618 78 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
response to light stimulus GO:0009416 87 0.015
regulation of meiosis GO:0040020 3 0.015
gastrulation with mouth forming second GO:0001702 1 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
positive regulation of protein catabolic process GO:0045732 75 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
epithelium development GO:0060429 227 0.014
neurogenesis GO:0022008 169 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
embryonic morphogenesis GO:0048598 85 0.014
protein import GO:0017038 130 0.014
positive regulation of immune system process GO:0002684 283 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
response to transforming growth factor beta GO:0071559 94 0.014
maintenance of protein location in cell GO:0032507 56 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
neuroblast proliferation GO:0007405 4 0.014
negative regulation of immune system process GO:0002683 136 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
regulation of cellular response to stress GO:0080135 244 0.014
regulation of response to dna damage stimulus GO:2001020 94 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
rho protein signal transduction GO:0007266 26 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
spermatid differentiation GO:0048515 4 0.014
embryo development GO:0009790 123 0.014
organelle assembly GO:0070925 176 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
oocyte development GO:0048599 1 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.013
rna interference GO:0016246 4 0.013
memory GO:0007613 3 0.013
regulation of cellular response to growth factor stimulus GO:0090287 76 0.013
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.013
immune system development GO:0002520 195 0.013
response to metal ion GO:0010038 84 0.013
histone modification GO:0016570 251 0.013
regulation of cell division GO:0051302 116 0.013
locomotory behavior GO:0007626 1 0.013
regulation of transcription factor import into nucleus GO:0042990 39 0.013
smad protein complex assembly GO:0007183 12 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
regulation of cell growth GO:0001558 135 0.013
regulation of developmental growth GO:0048638 30 0.013
nuclear division GO:0000280 128 0.013
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.013
long term memory GO:0007616 2 0.013
negative regulation of multi organism process GO:0043901 92 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
negative regulation of smad protein complex assembly GO:0010991 4 0.012
organic acid biosynthetic process GO:0016053 97 0.012
response to virus GO:0009615 126 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.012
regulation of hormone levels GO:0010817 125 0.012
regulation of protein targeting GO:1903533 91 0.012
g1 s transition of mitotic cell cycle GO:0000082 78 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
positive regulation of dendrite morphogenesis GO:0050775 3 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
regulation of immune response GO:0050776 201 0.012
vacuolar transport GO:0007034 34 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
regulation of secretion GO:0051046 194 0.012
canonical wnt signaling pathway GO:0060070 116 0.012
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.012
cell division GO:0051301 168 0.012
stem cell differentiation GO:0048863 93 0.012
chromatin assembly or disassembly GO:0006333 78 0.012
fatty acid metabolic process GO:0006631 115 0.012
negative regulation of growth GO:0045926 97 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
Mouse
protein homooligomerization GO:0051260 100 0.012
negative regulation of transferase activity GO:0051348 124 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
regulation of cell differentiation GO:0045595 393 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.012
protein acetylation GO:0006473 116 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.012
microtubule based process GO:0007017 210 0.012
reproductive process GO:0022414 106 0.012
response to hypoxia GO:0001666 96 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
regulation of dna metabolic process GO:0051052 153 0.012
rab protein signal transduction GO:0032482 4 0.011
response to steroid hormone GO:0048545 80 0.011
aging GO:0007568 66 0.011
lysosomal transport GO:0007041 33 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.011
chromatin modification GO:0016568 298 0.011
regulation of protein localization to nucleus GO:1900180 85 0.011
spermatid development GO:0007286 4 0.011
regulation of transmembrane transport GO:0034762 139 0.011
macromolecule methylation GO:0043414 97 0.011
receptor mediated endocytosis GO:0006898 84 0.011
neuron projection development GO:0031175 106 0.011
regulation of peptidase activity GO:0052547 180 0.011
neuron differentiation GO:0030182 138 0.011
vasculature development GO:0001944 181 0.011
Mouse
single organism carbohydrate metabolic process GO:0044723 193 0.011
positive regulation of wnt signaling pathway GO:0030177 54 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
metencephalon development GO:0022037 2 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
response to alcohol GO:0097305 64 0.011
positive regulation of rab gtpase activity GO:0032851 39 0.011
regulation of dephosphorylation GO:0035303 96 0.011
response to inorganic substance GO:0010035 127 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
regulation of receptor mediated endocytosis GO:0048259 32 0.011
blastocyst development GO:0001824 3 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
membrane organization GO:0061024 292 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.011
positive regulation of transferase activity GO:0051347 227 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
positive regulation of meiotic cell cycle GO:0051446 2 0.011
adult locomotory behavior GO:0008344 1 0.011
tube morphogenesis GO:0035239 95 0.011
neural tube closure GO:0001843 3 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.010
response to drug GO:0042493 81 0.010
establishment of planar polarity GO:0001736 3 0.010
regulation of response to external stimulus GO:0032101 222 0.010
nucleus localization GO:0051647 1 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
neurological system process GO:0050877 163 0.010
regulation of response to biotic stimulus GO:0002831 55 0.010
protein maturation GO:0051604 233 0.010
ribonucleoside monophosphate catabolic process GO:0009158 158 0.010
viral process GO:0016032 146 0.010
response to lipid GO:0033993 206 0.010
histone lysine methylation GO:0034968 50 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
retrograde transport endosome to golgi GO:0042147 45 0.010
regulation of transmembrane transporter activity GO:0022898 74 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
cellular protein complex assembly GO:0043623 188 0.010
digestive system development GO:0055123 75 0.010
circulatory system development GO:0072359 262 0.010
Mouse

LEMD3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.031
nervous system disease DOID:863 431 0.031
cancer DOID:162 167 0.028
disease of cellular proliferation DOID:14566 174 0.028
organ system cancer DOID:0050686 164 0.023
neurodegenerative disease DOID:1289 102 0.015
sensory system disease DOID:0050155 203 0.010
eye and adnexa disease DOID:1492 150 0.010
musculoskeletal system disease DOID:17 223 0.007
connective tissue disease DOID:65 109 0.003
bone disease DOID:0080001 88 0.003
bone remodeling disease DOID:0080005 26 0.001
osteosclerosis DOID:4254 16 0.001