Homo sapiens

19 known processes

ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

(Aliases: KIAA0165,ESP1,FLJ46492)

ESPL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic nuclear division GO:0007067 119 0.544
sister chromatid segregation GO:0000819 54 0.535
mitotic sister chromatid segregation GO:0000070 53 0.478
spindle assembly GO:0051225 29 0.393
purine nucleoside triphosphate metabolic process GO:0009144 412 0.380
regulation of cell cycle GO:0051726 393 0.312
organelle fission GO:0048285 149 0.296
nuclear division GO:0000280 128 0.268
mitotic cell cycle process GO:1903047 286 0.219
ribonucleoside triphosphate catabolic process GO:0009203 391 0.210
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.193
ribonucleoside triphosphate metabolic process GO:0009199 412 0.191
cellular macromolecular complex assembly GO:0034622 324 0.187
ribonucleoside catabolic process GO:0042454 406 0.180
nucleotide catabolic process GO:0009166 408 0.158
meiosis i GO:0007127 4 0.155
Mouse
centrosome organization GO:0051297 58 0.151
regulation of chromosome segregation GO:0051983 44 0.151
purine ribonucleoside metabolic process GO:0046128 437 0.143
establishment of nucleus localization GO:0040023 1 0.143
ribonucleotide catabolic process GO:0009261 405 0.140
regulation of cell cycle process GO:0010564 266 0.139
atp catabolic process GO:0006200 157 0.137
positive regulation of exit from mitosis GO:0031536 2 0.133
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.128
purine nucleoside monophosphate metabolic process GO:0009126 186 0.121
negative regulation of cellular component organization GO:0051129 235 0.112
negative regulation of protein maturation GO:1903318 142 0.108
purine nucleoside catabolic process GO:0006152 398 0.106
nucleoside triphosphate metabolic process GO:0009141 422 0.100
purine ribonucleotide catabolic process GO:0009154 404 0.098
nucleoside catabolic process GO:0009164 408 0.096
regulation of mitotic cell cycle GO:0007346 189 0.095
chromatin modification GO:0016568 298 0.093
organophosphate catabolic process GO:0046434 430 0.093
positive regulation of cell cycle process GO:0090068 106 0.090
ribonucleoside monophosphate metabolic process GO:0009161 187 0.090
regulation of protein maturation GO:1903317 150 0.090
post embryonic development GO:0009791 2 0.089
microtubule based process GO:0007017 210 0.083
Mouse
purine containing compound catabolic process GO:0072523 411 0.082
nucleoside phosphate catabolic process GO:1901292 412 0.081
ubiquitin dependent protein catabolic process GO:0006511 206 0.081
dna biosynthetic process GO:0071897 40 0.081
vesicle mediated transport GO:0016192 371 0.079
purine nucleoside monophosphate catabolic process GO:0009128 158 0.078
single organism cellular localization GO:1902580 332 0.077
mitotic cell cycle GO:0000278 326 0.076
ribonucleoside monophosphate catabolic process GO:0009158 158 0.075
dna replication GO:0006260 116 0.071
glycosyl compound catabolic process GO:1901658 413 0.071
chromatin organization GO:0006325 351 0.071
chromosome segregation GO:0007059 114 0.068
positive regulation of cellular catabolic process GO:0031331 284 0.068
organelle assembly GO:0070925 176 0.066
regulation of mitotic sister chromatid segregation GO:0033047 27 0.066
negative regulation of hydrolase activity GO:0051346 182 0.065
cellular protein complex assembly GO:0043623 188 0.064
protein ubiquitination GO:0016567 314 0.064
nucleoside triphosphate catabolic process GO:0009143 394 0.062
negative regulation of peptidase activity GO:0010466 91 0.061
positive regulation of catabolic process GO:0009896 310 0.060
purine ribonucleoside catabolic process GO:0046130 398 0.058
atp metabolic process GO:0046034 176 0.058
regulation of protein processing GO:0070613 150 0.057
dna conformation change GO:0071103 113 0.057
cell cycle phase transition GO:0044770 173 0.055
male meiosis GO:0007140 1 0.055
nucleus localization GO:0051647 1 0.054
negative regulation of catalytic activity GO:0043086 335 0.053
determination of adult lifespan GO:0008340 2 0.053
purine nucleotide catabolic process GO:0006195 405 0.053
embryo development GO:0009790 123 0.052
nucleoside monophosphate catabolic process GO:0009125 159 0.051
dephosphorylation GO:0016311 209 0.051
cellular component morphogenesis GO:0032989 314 0.050
mitotic cell cycle phase transition GO:0044772 162 0.046
regulation of endopeptidase activity GO:0052548 170 0.046
regulation of cellular component biogenesis GO:0044087 281 0.045
oocyte differentiation GO:0009994 2 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.044
oogenesis GO:0048477 2 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
protein catabolic process GO:0030163 325 0.043
nucleoside monophosphate metabolic process GO:0009123 191 0.042
spindle organization GO:0007051 53 0.041
Mouse
cellular component disassembly GO:0022411 92 0.041
female gamete generation GO:0007292 2 0.040
positive regulation of protein kinase activity GO:0045860 190 0.040
dna geometric change GO:0032392 32 0.040
nervous system development GO:0007399 293 0.039
regulation of proteolysis GO:0030162 293 0.039
regulation of peptidase activity GO:0052547 180 0.039
cellular ketone metabolic process GO:0042180 80 0.038
anterior posterior axis specification GO:0009948 2 0.038
protein maturation GO:0051604 233 0.038
cellular amino acid metabolic process GO:0006520 116 0.038
dna repair GO:0006281 198 0.037
negative regulation of protein metabolic process GO:0051248 391 0.036
cellular response to dna damage stimulus GO:0006974 379 0.036
negative regulation of endopeptidase activity GO:0010951 84 0.035
cell development GO:0048468 328 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.034
cell cycle g2 m phase transition GO:0044839 43 0.032
modification dependent macromolecule catabolic process GO:0043632 212 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
protein processing GO:0016485 226 0.031
endocytosis GO:0006897 159 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.030
double strand break repair GO:0006302 101 0.030
protein localization to organelle GO:0033365 280 0.030
protein polymerization GO:0051258 71 0.029
modification dependent protein catabolic process GO:0019941 209 0.029
meiotic chromosome segregation GO:0045132 4 0.028
Mouse
positive regulation of mitotic cell cycle GO:0045931 60 0.028
multicellular organismal aging GO:0010259 3 0.028
cell division GO:0051301 168 0.027
covalent chromatin modification GO:0016569 254 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
negative regulation of protein processing GO:0010955 142 0.026
dna recombination GO:0006310 77 0.026
cell cycle checkpoint GO:0000075 117 0.026
dna packaging GO:0006323 77 0.026
negative regulation of proteolysis GO:0045861 132 0.025
regulation of chromosome organization GO:0033044 103 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.025
dna duplex unwinding GO:0032508 30 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
positive regulation of organelle organization GO:0010638 195 0.024
cellular homeostasis GO:0019725 196 0.023
golgi organization GO:0007030 38 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
response to organic cyclic compound GO:0014070 204 0.023
organelle localization GO:0051640 84 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
reproduction GO:0000003 63 0.022
Mouse
negative regulation of mitotic cell cycle GO:0045930 102 0.022
regulation of cell cycle phase transition GO:1901987 126 0.022
negative regulation of cell size GO:0045792 3 0.022
regulation of protein kinase activity GO:0045859 289 0.022
centrosome cycle GO:0007098 32 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
single organism reproductive process GO:0044702 98 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
negative regulation of cell death GO:0060548 345 0.020
positive regulation of cell cycle GO:0045787 140 0.019
negative regulation of cell cycle GO:0045786 193 0.019
cell morphogenesis GO:0000902 296 0.019
regulation of protein localization GO:0032880 296 0.019
response to biotic stimulus GO:0009607 276 0.019
regulation of phosphatase activity GO:0010921 81 0.019
microtubule organizing center organization GO:0031023 62 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
immune response GO:0006955 307 0.019
establishment of cell polarity GO:0030010 22 0.019
cellular protein catabolic process GO:0044257 261 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
glomerular epithelial cell development GO:0072310 3 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
cell cycle g1 s phase transition GO:0044843 80 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
Mouse
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
regulation of protein polymerization GO:0032271 63 0.017
cytokinesis GO:0000910 96 0.017
positive regulation of hydrolase activity GO:0051345 331 0.016
positive regulation of proteolysis GO:0045862 142 0.016
response to abiotic stimulus GO:0009628 336 0.016
positive regulation of developmental process GO:0051094 314 0.016
regulation of cell differentiation GO:0045595 393 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
neuromuscular junction development GO:0007528 3 0.016
actin filament based process GO:0030029 224 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.016
histone exchange GO:0043486 3 0.016
maintenance of location GO:0051235 112 0.016
amine metabolic process GO:0009308 44 0.016
regulation of kinase activity GO:0043549 314 0.015
protein complex disassembly GO:0043241 52 0.015
mitotic cell cycle checkpoint GO:0007093 68 0.015
regulation of microtubule based process GO:0032886 74 0.015
neurogenesis GO:0022008 169 0.015
meiotic cell cycle GO:0051321 13 0.015
Mouse
sister chromatid biorientation GO:0031134 2 0.015
protein dephosphorylation GO:0006470 81 0.015
establishment or maintenance of cell polarity GO:0007163 31 0.015
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.015
positive regulation of chromosome organization GO:2001252 41 0.014
nuclear migration GO:0007097 1 0.014
reproductive process GO:0022414 106 0.014
response to oxygen containing compound GO:1901700 369 0.014
protein targeting GO:0006605 187 0.014
regulation of dephosphorylation GO:0035303 96 0.014
mitotic sister chromatid separation GO:0051306 18 0.014
membrane organization GO:0061024 292 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
cytoplasmic transport GO:0016482 379 0.014
methylation GO:0032259 106 0.014
protein k11 linked ubiquitination GO:0070979 24 0.014
synaptic transmission cholinergic GO:0007271 2 0.014
interspecies interaction between organisms GO:0044419 156 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
anatomical structure homeostasis GO:0060249 100 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
histone modification GO:0016570 251 0.013
regulation of transferase activity GO:0051338 355 0.013
positive regulation of nuclear division GO:0051785 27 0.013
g2 m transition of mitotic cell cycle GO:0000086 41 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
growth GO:0040007 202 0.013
regulation of cellular component size GO:0032535 82 0.013
regulation of cell activation GO:0050865 125 0.013
eye photoreceptor cell differentiation GO:0001754 2 0.013
negative regulation of developmental process GO:0051093 247 0.013
cellular response to endogenous stimulus GO:0071495 336 0.012
regulation of protein complex assembly GO:0043254 147 0.012
dna dependent dna replication GO:0006261 44 0.012
ras protein signal transduction GO:0007265 73 0.012
response to external biotic stimulus GO:0043207 261 0.012
single organism membrane organization GO:0044802 268 0.012
chemical homeostasis GO:0048878 306 0.012
microtubule nucleation GO:0007020 6 0.012
multi organism cellular process GO:0044764 156 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
chromatin remodeling GO:0006338 55 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
protein k48 linked ubiquitination GO:0070936 38 0.012
regulation of cell division GO:0051302 116 0.012
regulation of cell cycle g1 s phase transition GO:1902806 42 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.012
regulation of immune effector process GO:0002697 91 0.012
negative regulation of phosphorylation GO:0042326 174 0.011
oocyte development GO:0048599 1 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
regulation of nuclear division GO:0051783 65 0.011
protein methylation GO:0006479 74 0.011
cellular protein complex disassembly GO:0043624 36 0.011
intracellular protein transport GO:0006886 270 0.011
response to decreased oxygen levels GO:0036293 96 0.011
myosin filament assembly GO:0031034 2 0.011
peptidyl lysine modification GO:0018205 144 0.011
regulation of dna metabolic process GO:0051052 153 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
microtubule polymerization GO:0046785 18 0.011
positive regulation of immune system process GO:0002684 283 0.011
negative regulation of transport GO:0051051 176 0.011
dna damage checkpoint GO:0000077 68 0.011
activation of protein kinase activity GO:0032147 90 0.011
spermatid development GO:0007286 4 0.011
nucleus organization GO:0006997 28 0.010
negative regulation of methylation dependent chromatin silencing GO:0090310 2 0.010
carbohydrate derivative biosynthetic process GO:1901137 207 0.010
myosin filament organization GO:0031033 2 0.010
response to other organism GO:0051707 261 0.010
regulation of cell development GO:0060284 161 0.010
signal transduction by phosphorylation GO:0023014 297 0.010

ESPL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.079
cancer DOID:162 167 0.037
gastrointestinal system cancer DOID:3119 52 0.033
organ system cancer DOID:0050686 164 0.033
bone development disease DOID:0080006 55 0.015
bone disease DOID:0080001 88 0.015
dysostosis DOID:1934 22 0.015
musculoskeletal system disease DOID:17 223 0.015
connective tissue disease DOID:65 109 0.015
synostosis DOID:11971 10 0.015