Homo sapiens

36 known processes

MLL4

myeloid/lymphoid or mixed-lineage leukemia 4

(Aliases: TRX2,MLL2,WBP7,HRX2,KIAA0304)

MLL4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
female gamete generation GO:0007292 2 0.346
Mouse
purine nucleotide catabolic process GO:0006195 405 0.278
regulation of cellular ketone metabolic process GO:0010565 50 0.249
histone modification GO:0016570 251 0.241
covalent chromatin modification GO:0016569 254 0.230
peptidyl lysine modification GO:0018205 144 0.226
glycosyl compound catabolic process GO:1901658 413 0.216
ribonucleoside triphosphate catabolic process GO:0009203 391 0.202
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.195
amine metabolic process GO:0009308 44 0.188
ribonucleoside triphosphate metabolic process GO:0009199 412 0.185
cell development GO:0048468 328 0.182
Mouse Fly
histone methylation GO:0016571 60 0.181
regulation of cellular amino acid metabolic process GO:0006521 6 0.178
chromatin organization GO:0006325 351 0.176
nucleoside triphosphate catabolic process GO:0009143 394 0.172
positive regulation of programmed cell death GO:0043068 249 0.159
cellular ketone metabolic process GO:0042180 80 0.157
chromatin modification GO:0016568 298 0.153
cellular amino acid metabolic process GO:0006520 116 0.150
oocyte differentiation GO:0009994 2 0.145
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.138
mitotic cell cycle GO:0000278 326 0.128
purine ribonucleotide catabolic process GO:0009154 404 0.124
cranial nerve development GO:0021545 4 0.123
nervous system development GO:0007399 293 0.123
Fly
nucleoside catabolic process GO:0009164 408 0.120
regulation of gtpase activity GO:0043087 180 0.116
regulation of cellular amine metabolic process GO:0033238 11 0.112
internal peptidyl lysine acetylation GO:0018393 97 0.112
Fly
cell cycle phase transition GO:0044770 173 0.111
oogenesis GO:0048477 2 0.110
Mouse
regulation of nucleotide metabolic process GO:0006140 269 0.109
regulation of nucleotide catabolic process GO:0030811 205 0.109
nerve development GO:0021675 4 0.107
positive regulation of cell death GO:0010942 263 0.106
jnk cascade GO:0007254 80 0.105
mitotic cell cycle process GO:1903047 286 0.104
regulation of cell cycle GO:0051726 393 0.104
nucleotide catabolic process GO:0009166 408 0.102
purine nucleoside catabolic process GO:0006152 398 0.098
enzyme linked receptor protein signaling pathway GO:0007167 303 0.097
regulation of cell cycle process GO:0010564 266 0.093
positive regulation of nucleotide catabolic process GO:0030813 185 0.092
cardiovascular system development GO:0072358 262 0.086
ribonucleoside catabolic process GO:0042454 406 0.085
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.084
purine ribonucleoside catabolic process GO:0046130 398 0.081
apoptotic signaling pathway GO:0097190 268 0.080
oocyte development GO:0048599 1 0.079
nucleoside triphosphate metabolic process GO:0009141 422 0.079
cell division GO:0051301 168 0.079
proteoglycan catabolic process GO:0030167 3 0.078
hindbrain development GO:0030902 3 0.074
purine containing compound catabolic process GO:0072523 411 0.071
ribonucleotide catabolic process GO:0009261 405 0.070
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.070
gtp metabolic process GO:0046039 239 0.070
positive regulation of apoptotic process GO:0043065 246 0.069
response to abiotic stimulus GO:0009628 336 0.069
cellular amine metabolic process GO:0044106 41 0.068
negative regulation of wnt signaling pathway GO:0030178 69 0.068
stem cell division GO:0017145 2 0.067
cellular response to dna damage stimulus GO:0006974 379 0.067
Fly
positive regulation of cell proliferation GO:0008284 301 0.066
wnt signaling pathway GO:0016055 156 0.066
positive regulation of cellular component organization GO:0051130 376 0.065
guanosine containing compound catabolic process GO:1901069 239 0.064
positive regulation of cellular amine metabolic process GO:0033240 7 0.063
mitotic cell cycle phase transition GO:0044772 162 0.063
protein ubiquitination GO:0016567 314 0.062
circulatory system development GO:0072359 262 0.062
gtp catabolic process GO:0006184 237 0.061
regulation of cellular response to growth factor stimulus GO:0090287 76 0.061
protein alkylation GO:0008213 74 0.059
signal transduction by phosphorylation GO:0023014 297 0.059
regulation of purine nucleotide metabolic process GO:1900542 264 0.059
cellular component morphogenesis GO:0032989 314 0.058
Fly
internal protein amino acid acetylation GO:0006475 101 0.057
Fly
positive regulation of catabolic process GO:0009896 310 0.056
neuron differentiation GO:0030182 138 0.056
Fly
cell projection organization GO:0030030 252 0.056
Fly
post embryonic development GO:0009791 2 0.056
taxis GO:0042330 157 0.055
Fly
negative regulation of multicellular organismal process GO:0051241 317 0.055
organophosphate catabolic process GO:0046434 430 0.054
determination of adult lifespan GO:0008340 2 0.054
anatomical structure formation involved in morphogenesis GO:0048646 284 0.052
metal ion transport GO:0030001 272 0.051
protein acylation GO:0043543 138 0.051
Fly
generation of neurons GO:0048699 152 0.051
Fly
regulation of apoptotic signaling pathway GO:2001233 175 0.050
cellular response to endogenous stimulus GO:0071495 336 0.049
regulation of cellular response to stress GO:0080135 244 0.049
Fly
multicellular organismal aging GO:0010259 3 0.049
negative regulation of programmed cell death GO:0043069 321 0.049
negative regulation of protein metabolic process GO:0051248 391 0.048
regulation of mitotic cell cycle GO:0007346 189 0.048
regulation of mapk cascade GO:0043408 262 0.048
rho protein signal transduction GO:0007266 26 0.047
positive regulation of odontogenesis GO:0042482 3 0.047
positive regulation of cellular catabolic process GO:0031331 284 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.046
negative regulation of cellular response to hepatocyte growth factor stimulus GO:2001113 1 0.046
cell adhesion GO:0007155 325 0.046
positive regulation of developmental process GO:0051094 314 0.045
negative regulation of developmental process GO:0051093 247 0.044
segmentation GO:0035282 4 0.044
purine nucleoside triphosphate catabolic process GO:0009146 392 0.044
response to axon injury GO:0048678 1 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.042
ras protein signal transduction GO:0007265 73 0.042
protein acetylation GO:0006473 116 0.041
Fly
cell part morphogenesis GO:0032990 137 0.041
Fly
response to uv GO:0009411 73 0.041
regulation of response to external stimulus GO:0032101 222 0.041
metencephalon development GO:0022037 2 0.040
mitotic nuclear division GO:0007067 119 0.040
cellular macromolecule catabolic process GO:0044265 380 0.040
negative regulation of cellular protein metabolic process GO:0032269 353 0.040
histone h3 k4 methylation GO:0051568 27 0.039
response to radiation GO:0009314 151 0.039
positive regulation of hydrolase activity GO:0051345 331 0.038
monovalent inorganic cation transport GO:0015672 128 0.038
protein catabolic process GO:0030163 325 0.038
chemotaxis GO:0006935 157 0.037
Fly
positive regulation of nucleoside metabolic process GO:0045979 186 0.037
cytokine production GO:0001816 247 0.037
neurogenesis GO:0022008 169 0.037
Fly
epithelial cell migration GO:0010631 119 0.037
regulation of cellular component movement GO:0051270 334 0.037
cranial nerve morphogenesis GO:0021602 1 0.037
mrna metabolic process GO:0016071 175 0.036
anterior posterior axis specification GO:0009948 2 0.035
spinal cord development GO:0021510 4 0.035
response to light stimulus GO:0009416 87 0.035
regulation of cell migration GO:0030334 289 0.035
negative regulation of cell differentiation GO:0045596 171 0.035
ribonucleoprotein complex biogenesis GO:0022613 116 0.035
posttranscriptional regulation of gene expression GO:0010608 213 0.034
regulation of cell division GO:0051302 116 0.034
immune system development GO:0002520 195 0.034
regulation of cell motility GO:2000145 299 0.034
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.034
canonical wnt signaling pathway GO:0060070 116 0.034
small gtpase mediated signal transduction GO:0007264 78 0.034
negative regulation of cell cycle GO:0045786 193 0.034
cell growth GO:0016049 160 0.034
regulation of canonical wnt signaling pathway GO:0060828 88 0.034
neuron projection regeneration GO:0031102 1 0.034
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.033
regulation of purine nucleotide catabolic process GO:0033121 205 0.033
chromosome segregation GO:0007059 114 0.033
regulation of cell cycle phase transition GO:1901987 126 0.033
positive regulation of gtpase activity GO:0043547 166 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.033
protein maturation GO:0051604 233 0.033
central nervous system development GO:0007417 123 0.033
organelle assembly GO:0070925 176 0.033
negative regulation of cell cycle process GO:0010948 121 0.032
growth GO:0040007 202 0.032
regulation of wnt signaling pathway GO:0030111 123 0.032
response to growth factor GO:0070848 205 0.032
compound eye development GO:0048749 1 0.032
actin cytoskeleton organization GO:0030036 207 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.031
nucleoside phosphate catabolic process GO:1901292 412 0.031
single organism reproductive process GO:0044702 98 0.031
Mouse Fly
regulation of gtp catabolic process GO:0033124 180 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
neuron projection development GO:0031175 106 0.031
Fly
negative regulation of cell death GO:0060548 345 0.030
blastocyst development GO:0001824 3 0.030
peptidyl lysine acetylation GO:0018394 101 0.030
Fly
cytoplasmic transport GO:0016482 379 0.030
morphogenesis of embryonic epithelium GO:0016331 4 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
dna repair GO:0006281 198 0.030
positive regulation of nucleotide metabolic process GO:0045981 230 0.030
protein processing GO:0016485 226 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.029
regulation of gene expression epigenetic GO:0040029 73 0.029
cell morphogenesis GO:0000902 296 0.029
Fly
regulation of protein processing GO:0070613 150 0.029
modification dependent macromolecule catabolic process GO:0043632 212 0.029
cell morphogenesis involved in differentiation GO:0000904 144 0.029
Fly
hematopoietic or lymphoid organ development GO:0048534 186 0.028
organelle fission GO:0048285 149 0.028
single organismal cell cell adhesion GO:0016337 148 0.028
rna processing GO:0006396 255 0.028
secretion GO:0046903 254 0.028
protein localization to organelle GO:0033365 280 0.028
immune effector process GO:0002252 159 0.028
ribonucleoprotein complex subunit organization GO:0071826 81 0.028
regulation of rho protein signal transduction GO:0035023 79 0.028
leukocyte mediated immunity GO:0002443 59 0.028
positive regulation of cell cycle process GO:0090068 106 0.028
asymmetric stem cell division GO:0098722 1 0.027
calcium ion transport GO:0006816 147 0.027
positive regulation of organelle organization GO:0010638 195 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
sodium ion transport GO:0006814 61 0.027
activation of immune response GO:0002253 114 0.027
cation transport GO:0006812 331 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.026
cellular protein catabolic process GO:0044257 261 0.026
motor neuron axon guidance GO:0008045 2 0.026
negative regulation of hepatocyte growth factor receptor signaling pathway GO:1902203 1 0.026
histone acetylation GO:0016573 93 0.026
Fly
modification dependent protein catabolic process GO:0019941 209 0.026
negative regulation of epithelial cell migration GO:0010633 38 0.026
somatic stem cell division GO:0048103 1 0.025
negative regulation of response to wounding GO:1903035 47 0.025
embryo development GO:0009790 123 0.024
vesicle mediated transport GO:0016192 371 0.024
response to hormone GO:0009725 175 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
regulation of kinase activity GO:0043549 314 0.024
neuroblast proliferation GO:0007405 4 0.024
brain development GO:0007420 97 0.024
behavior GO:0007610 112 0.024
tissue migration GO:0090130 119 0.024
regulation of nucleoside metabolic process GO:0009118 209 0.024
cell type specific apoptotic process GO:0097285 125 0.023
regulation of locomotion GO:0040012 329 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
microtubule based process GO:0007017 210 0.023
negative regulation of mitotic cell cycle GO:0045930 102 0.023
positive regulation of protein kinase activity GO:0045860 190 0.023
biological adhesion GO:0022610 331 0.023
regulation of mitotic cell cycle phase transition GO:1901990 118 0.023
cell projection morphogenesis GO:0048858 129 0.023
Fly
histone lysine methylation GO:0034968 50 0.023
protein methylation GO:0006479 74 0.023
regulation of cell adhesion GO:0030155 166 0.022
g1 s transition of mitotic cell cycle GO:0000082 78 0.022
positive regulation of ras gtpase activity GO:0032320 117 0.022
system process GO:0003008 349 0.022
microtubule cytoskeleton organization GO:0000226 176 0.022
regulation of protein localization GO:0032880 296 0.022
regulation of protein kinase activity GO:0045859 289 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
ion homeostasis GO:0050801 230 0.022
response to lipid GO:0033993 206 0.022
sulfur compound biosynthetic process GO:0044272 38 0.022
myeloid leukocyte differentiation GO:0002573 60 0.022
regulation of dna metabolic process GO:0051052 153 0.021
potassium ion transport GO:0006813 62 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.021
epithelium development GO:0060429 227 0.021
regulation of protein secretion GO:0050708 86 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.021
lipid localization GO:0010876 106 0.021
regulation of stress activated mapk cascade GO:0032872 84 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
negative regulation of cell cycle phase transition GO:1901988 89 0.021
dephosphorylation GO:0016311 209 0.021
intracellular estrogen receptor signaling pathway GO:0030520 23 0.021
intrinsic apoptotic signaling pathway GO:0097193 127 0.021
immune response GO:0006955 307 0.021
cell cycle g1 s phase transition GO:0044843 80 0.021
ubiquitin dependent protein catabolic process GO:0006511 206 0.020
regulation of cell growth GO:0001558 135 0.020
reproductive process GO:0022414 106 0.020
Mouse Fly
protein polyubiquitination GO:0000209 110 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.020
epithelium migration GO:0090132 119 0.020
sensory perception of pain GO:0019233 4 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
spermatid differentiation GO:0048515 4 0.020
regulation of cell differentiation GO:0045595 393 0.020
cell substrate adhesion GO:0031589 132 0.020
positive regulation of cell cycle GO:0045787 140 0.019
protein oligomerization GO:0051259 173 0.019
negative regulation of smoothened signaling pathway GO:0045879 3 0.019
regulation of cell development GO:0060284 161 0.019
nucleotide excision repair GO:0006289 31 0.019
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.019
regulation of map kinase activity GO:0043405 108 0.019
secretion by cell GO:0032940 226 0.019
leukocyte activation GO:0045321 164 0.019
actin filament based process GO:0030029 224 0.019
hemopoiesis GO:0030097 180 0.019
negative regulation of locomotion GO:0040013 118 0.019
limbic system development GO:0021761 3 0.019
blood vessel morphogenesis GO:0048514 162 0.018
spermatid development GO:0007286 4 0.018
ion transmembrane transport GO:0034220 338 0.018
regulation of cellular response to hepatocyte growth factor stimulus GO:2001112 1 0.018
single organism cell adhesion GO:0098602 179 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
regulation of secretion GO:0051046 194 0.018
neuromuscular junction development GO:0007528 3 0.018
cerebellum development GO:0021549 2 0.018
positive regulation of cell migration GO:0030335 172 0.018
nucleus localization GO:0051647 1 0.018
ribonucleoprotein complex assembly GO:0022618 78 0.018
cell matrix adhesion GO:0007160 85 0.018
cation transmembrane transport GO:0098655 238 0.018
blood vessel development GO:0001568 172 0.018
exocytosis GO:0006887 71 0.017
tissue regeneration GO:0042246 3 0.017
neuron projection morphogenesis GO:0048812 50 0.017
Fly
regulation of body fluid levels GO:0050878 99 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.017
regeneration GO:0031099 4 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
endomembrane system organization GO:0010256 196 0.017
endocytosis GO:0006897 159 0.017
negative regulation of angiogenesis GO:0016525 39 0.017
negative regulation of cellular component movement GO:0051271 106 0.017
regulation of protein transport GO:0051223 213 0.017
negative regulation of vasculature development GO:1901343 43 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
mapk cascade GO:0000165 288 0.016
positive regulation of endothelial cell migration GO:0010595 39 0.016
mrna splicing via spliceosome GO:0000398 89 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
lipid transport GO:0006869 90 0.016
regulation of cytokine production GO:0001817 232 0.016
multi organism reproductive process GO:0044703 54 0.016
Mouse Fly
mitotic cell cycle checkpoint GO:0007093 68 0.016
regulation of dephosphorylation GO:0035303 96 0.016
i kappab kinase nf kappab signaling GO:0007249 166 0.016
leukocyte activation involved in immune response GO:0002366 30 0.016
regulation of ion transport GO:0043269 189 0.016
positive regulation of proteolysis GO:0045862 142 0.016
protein localization to membrane GO:0072657 160 0.016
negative regulation of ion transport GO:0043271 39 0.016
memory GO:0007613 3 0.016
response to wounding GO:0009611 168 0.016
membrane organization GO:0061024 292 0.016
protein deacylation GO:0035601 39 0.016
sodium ion transmembrane transport GO:0035725 59 0.016
neuroblast division GO:0055057 1 0.016
head development GO:0060322 108 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
neural tube formation GO:0001841 3 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
positive regulation of mapk cascade GO:0043410 190 0.015
divalent inorganic cation transport GO:0072511 158 0.015
regulation of proteolysis GO:0030162 293 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.015
plasma membrane organization GO:0007009 115 0.015
cellular response to abiotic stimulus GO:0071214 117 0.015
regulation of chromosome organization GO:0033044 103 0.015
Mouse
tube closure GO:0060606 3 0.015
multicellular organismal reproductive process GO:0048609 40 0.015
Mouse Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.015
somatic stem cell maintenance GO:0035019 4 0.015
ossification GO:0001503 121 0.015
developmental process involved in reproduction GO:0003006 66 0.015
Mouse
cell activation GO:0001775 213 0.015
regulation of epithelial cell migration GO:0010632 93 0.015
neural tube closure GO:0001843 3 0.015
rna splicing GO:0008380 131 0.015
establishment of nucleus localization GO:0040023 1 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
single organism cellular localization GO:1902580 332 0.015
regulation of endothelial cell migration GO:0010594 67 0.015
regulation of intracellular transport GO:0032386 195 0.015
meiotic chromosome segregation GO:0045132 4 0.014
protein autophosphorylation GO:0046777 123 0.014
myeloid cell differentiation GO:0030099 117 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
defense response GO:0006952 315 0.014
regulation of protein catabolic process GO:0042176 155 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
regulation of binding GO:0051098 111 0.014
protein localization to plasma membrane GO:0072659 93 0.014
protein secretion GO:0009306 98 0.014
renal water homeostasis GO:0003091 4 0.014
regulation of protein complex assembly GO:0043254 147 0.014
regulation of response to dna damage stimulus GO:2001020 94 0.014
Fly
positive regulation of rho gtpase activity GO:0032321 56 0.014
cytokine secretion GO:0050663 64 0.014
regulation of angiogenesis GO:0045765 92 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
negative regulation of cell migration GO:0030336 102 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
sensory organ development GO:0007423 52 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
positive regulation of chromosome organization GO:2001252 41 0.014
ncrna metabolic process GO:0034660 108 0.014
response to oxygen containing compound GO:1901700 369 0.014
protein homooligomerization GO:0051260 100 0.014
regulation of neurogenesis GO:0050767 82 0.014
endothelial cell migration GO:0043542 86 0.014
blastoderm segmentation GO:0007350 2 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.013
histone h4 k5 acetylation GO:0043981 15 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
cation homeostasis GO:0055080 189 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
cell cell junction organization GO:0045216 69 0.013
melanin metabolic process GO:0006582 1 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
reproductive system development GO:0061458 56 0.013
Mouse
cellular calcium ion homeostasis GO:0006874 117 0.013
osteoblast differentiation GO:0001649 92 0.013
negative regulation of protein modification process GO:0031400 200 0.013
response to endoplasmic reticulum stress GO:0034976 49 0.013
cellular response to hypoxia GO:0071456 51 0.013
sulfur compound metabolic process GO:0006790 101 0.013
negative regulation of phosphatase activity GO:0010923 61 0.013
cellular chemical homeostasis GO:0055082 180 0.013
response to oxygen levels GO:0070482 100 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
neuron death GO:0070997 65 0.013
peptidyl serine modification GO:0018209 106 0.013
regulation of membrane potential GO:0042391 95 0.013
histone h4 acetylation GO:0043967 47 0.013
regulation of peptidase activity GO:0052547 180 0.013
neuron development GO:0048666 113 0.012
Fly
negative regulation of cell adhesion GO:0007162 64 0.012
positive regulation of lymphocyte activation GO:0051251 73 0.012
positive regulation of chromatin modification GO:1903310 30 0.012
kidney development GO:0001822 53 0.012
response to external biotic stimulus GO:0043207 261 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
protein monoubiquitination GO:0006513 39 0.012
eye development GO:0001654 42 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
vasculature development GO:0001944 181 0.012
cell proliferation in forebrain GO:0021846 1 0.012
cellular response to uv GO:0034644 32 0.012
transmembrane transport GO:0055085 399 0.012
sexual reproduction GO:0019953 37 0.012
Mouse Fly
histone h4 k8 acetylation GO:0043982 15 0.012
activation of protein kinase activity GO:0032147 90 0.012
meiosis i GO:0007127 4 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
sister chromatid segregation GO:0000819 54 0.012
tube development GO:0035295 125 0.012
single organism membrane organization GO:0044802 268 0.012
cell fate determination GO:0001709 3 0.012
regulation of t cell activation GO:0050863 77 0.012
neural crest cell development GO:0014032 3 0.012
convergent extension GO:0060026 1 0.012
neuronal stem cell division GO:0036445 1 0.012
positive regulation of immune system process GO:0002684 283 0.012
adaptive immune response GO:0002250 49 0.012
signal transduction by p53 class mediator GO:0072331 72 0.012
muscle structure development GO:0061061 98 0.012
pattern specification process GO:0007389 43 0.011
regulation of calcium ion transport GO:0051924 79 0.011
regulation of neuron death GO:1901214 56 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
regulation of hepatocyte growth factor receptor signaling pathway GO:1902202 4 0.011
metaphase anaphase transition of cell cycle GO:0044784 21 0.011
negative regulation of transferase activity GO:0051348 124 0.011
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
lipid metabolic process GO:0006629 381 0.011
chromosome separation GO:0051304 23 0.011
heart development GO:0007507 95 0.011
leukocyte differentiation GO:0002521 98 0.011
blood coagulation GO:0007596 76 0.011
skeletal muscle satellite cell proliferation GO:0014841 1 0.011
maintenance of location GO:0051235 112 0.011
response to steroid hormone GO:0048545 80 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.011
stem cell differentiation GO:0048863 93 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.011
positive regulation of leukocyte activation GO:0002696 80 0.011
monosaccharide transport GO:0015749 32 0.011
receptor metabolic process GO:0043112 81 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
asymmetric neuroblast division GO:0055059 1 0.011
respiratory gaseous exchange GO:0007585 3 0.011
negative regulation of proteolysis GO:0045861 132 0.011
regulation of transferase activity GO:0051338 355 0.011
regulation of rho gtpase activity GO:0032319 66 0.011
divalent metal ion transport GO:0070838 152 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
nuclear division GO:0000280 128 0.011
positive regulation of transport GO:0051050 336 0.011
negative regulation of alpha beta t cell activation GO:0046636 3 0.011

MLL4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 70 0.020
immune system disease DOID:2914 155 0.017
musculoskeletal system disease DOID:17 223 0.017
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
neurodegenerative disease DOID:1289 102 0.011