Homo sapiens

104 known processes

VPRBP

Vpr (HIV-1) binding protein

(Aliases: DCAF1,MGC102804,KIAA0800)

VPRBP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone monoubiquitination GO:0010390 20 0.642
histone h2a ubiquitination GO:0033522 17 0.501
histone ubiquitination GO:0016574 31 0.325
histone h2a monoubiquitination GO:0035518 11 0.297
cellular response to dna damage stimulus GO:0006974 379 0.251
chromatin modification GO:0016568 298 0.242
regulation of cell cycle GO:0051726 393 0.239
protein ubiquitination GO:0016567 314 0.216
ubiquitin dependent protein catabolic process GO:0006511 206 0.209
modification dependent macromolecule catabolic process GO:0043632 212 0.208
cellular macromolecule catabolic process GO:0044265 380 0.191
covalent chromatin modification GO:0016569 254 0.175
chromatin organization GO:0006325 351 0.165
post embryonic development GO:0009791 2 0.157
protein catabolic process GO:0030163 325 0.151
regulation of cell cycle process GO:0010564 266 0.151
negative regulation of cell death GO:0060548 345 0.150
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.147
modification dependent protein catabolic process GO:0019941 209 0.145
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.134
cellular protein catabolic process GO:0044257 261 0.133
negative regulation of cell cycle GO:0045786 193 0.132
negative regulation of apoptotic process GO:0043066 316 0.129
mitotic cell cycle GO:0000278 326 0.129
dna repair GO:0006281 198 0.127
proteasomal protein catabolic process GO:0010498 176 0.125
regulation of dna metabolic process GO:0051052 153 0.122
wnt signaling pathway GO:0016055 156 0.116
cellular response to abiotic stimulus GO:0071214 117 0.113
mitotic cell cycle phase transition GO:0044772 162 0.107
cellular response to uv GO:0034644 32 0.104
protein monoubiquitination GO:0006513 39 0.092
regulation of mitotic cell cycle phase transition GO:1901990 118 0.087
mitotic cell cycle process GO:1903047 286 0.083
protein modification by small protein conjugation GO:0032446 342 0.082
regulation of mitotic cell cycle GO:0007346 189 0.076
uv damage excision repair GO:0070914 7 0.075
chromosome segregation GO:0007059 114 0.074
response to radiation GO:0009314 151 0.073
cell cycle phase transition GO:0044770 173 0.072
cellular response to radiation GO:0071478 65 0.071
response to abiotic stimulus GO:0009628 336 0.065
vesicle mediated transport GO:0016192 371 0.064
dna integrity checkpoint GO:0031570 71 0.062
negative regulation of multicellular organismal process GO:0051241 317 0.062
ribonucleoside triphosphate catabolic process GO:0009203 391 0.060
purine nucleotide catabolic process GO:0006195 405 0.059
regulation of cellular ketone metabolic process GO:0010565 50 0.059
response to uv GO:0009411 73 0.059
regulation of cell cycle phase transition GO:1901987 126 0.058
negative regulation of programmed cell death GO:0043069 321 0.058
negative regulation of glial cell proliferation GO:0060253 2 0.057
meiotic chromosome segregation GO:0045132 4 0.056
regulation of cellular amine metabolic process GO:0033238 11 0.054
regulation of cell differentiation GO:0045595 393 0.054
cellular amino acid metabolic process GO:0006520 116 0.053
nucleoside phosphate catabolic process GO:1901292 412 0.053
negative regulation of protein metabolic process GO:0051248 391 0.052
regulation of cellular amino acid metabolic process GO:0006521 6 0.052
amine metabolic process GO:0009308 44 0.051
multicellular organismal aging GO:0010259 3 0.049
growth GO:0040007 202 0.049
cellular amine metabolic process GO:0044106 41 0.048
response to light stimulus GO:0009416 87 0.047
purine ribonucleotide catabolic process GO:0009154 404 0.047
regulation of transferase activity GO:0051338 355 0.047
cellular response to light stimulus GO:0071482 34 0.045
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.045
cell cycle checkpoint GO:0000075 117 0.044
cellular ketone metabolic process GO:0042180 80 0.043
purine containing compound catabolic process GO:0072523 411 0.043
dna damage checkpoint GO:0000077 68 0.043
oocyte differentiation GO:0009994 2 0.042
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.042
mapk cascade GO:0000165 288 0.042
hematopoietic or lymphoid organ development GO:0048534 186 0.041
positive regulation of cell proliferation GO:0008284 301 0.041
organelle fission GO:0048285 149 0.041
negative regulation of gliogenesis GO:0014014 3 0.040
segmentation GO:0035282 4 0.038
organophosphate catabolic process GO:0046434 430 0.038
regulation of glial cell proliferation GO:0060251 4 0.037
regulation of protein catabolic process GO:0042176 155 0.036
positive regulation of cellular component organization GO:0051130 376 0.036
regulation of establishment of protein localization GO:0070201 242 0.036
somatic stem cell maintenance GO:0035019 4 0.036
regulation of cellular component biogenesis GO:0044087 281 0.034
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.034
microtubule based process GO:0007017 210 0.034
regulation of growth GO:0040008 165 0.033
positive regulation of cell cycle process GO:0090068 106 0.033
purine nucleoside triphosphate metabolic process GO:0009144 412 0.033
hemopoiesis GO:0030097 180 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.033
negative regulation of catalytic activity GO:0043086 335 0.033
regulation of locomotion GO:0040012 329 0.033
regulation of cell growth GO:0001558 135 0.033
nucleoside triphosphate catabolic process GO:0009143 394 0.032
negative regulation of cell cycle process GO:0010948 121 0.032
regulation of cell motility GO:2000145 299 0.032
mitotic nuclear division GO:0007067 119 0.031
purine ribonucleoside metabolic process GO:0046128 437 0.031
regulation of protein localization GO:0032880 296 0.030
regulation of proteolysis GO:0030162 293 0.030
determination of adult lifespan GO:0008340 2 0.030
myeloid leukocyte differentiation GO:0002573 60 0.030
glycosyl compound catabolic process GO:1901658 413 0.030
regulation of cell cycle g1 s phase transition GO:1902806 42 0.030
histone modification GO:0016570 251 0.029
regulation of kinase activity GO:0043549 314 0.029
nucleoside catabolic process GO:0009164 408 0.029
regulation of cell migration GO:0030334 289 0.028
peptidyl tyrosine modification GO:0018212 170 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
negative regulation of developmental process GO:0051093 247 0.027
negative regulation of protein processing GO:0010955 142 0.027
lipid metabolic process GO:0006629 381 0.027
female gamete generation GO:0007292 2 0.026
protein maturation GO:0051604 233 0.026
actin filament based process GO:0030029 224 0.026
signal transduction by phosphorylation GO:0023014 297 0.026
regulation of myeloid cell differentiation GO:0045637 81 0.026
regulation of leukocyte differentiation GO:1902105 61 0.026
regulation of cellular component movement GO:0051270 334 0.025
positive regulation of protein phosphorylation GO:0001934 313 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
cell morphogenesis GO:0000902 296 0.025
nucleoside monophosphate metabolic process GO:0009123 191 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
cell development GO:0048468 328 0.024
nucleotide catabolic process GO:0009166 408 0.024
negative regulation of cell proliferation GO:0008285 228 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
cell growth GO:0016049 160 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
carbohydrate metabolic process GO:0005975 207 0.024
regulation of cytoskeleton organization GO:0051493 177 0.023
thymus development GO:0048538 3 0.023
regulation of protein transport GO:0051223 213 0.023
positive regulation of cell cycle GO:0045787 140 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.023
leukocyte differentiation GO:0002521 98 0.023
protein modification by small protein removal GO:0070646 92 0.022
cytoplasmic transport GO:0016482 379 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
protein targeting GO:0006605 187 0.022
regulation of protein processing GO:0070613 150 0.022
purine nucleoside monophosphate catabolic process GO:0009128 158 0.022
positive regulation of protein catabolic process GO:0045732 75 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
atp metabolic process GO:0046034 176 0.021
nuclear transport GO:0051169 179 0.021
regulation of cellular protein catabolic process GO:1903362 96 0.021
oocyte development GO:0048599 1 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
negative regulation of proteolysis GO:0045861 132 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
biological adhesion GO:0022610 331 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
regulation of protein kinase activity GO:0045859 289 0.021
blastoderm segmentation GO:0007350 2 0.021
negative regulation of protein modification process GO:0031400 200 0.020
protein autoubiquitination GO:0051865 37 0.020
regulation of protein maturation GO:1903317 150 0.020
regulation of proteasomal protein catabolic process GO:0061136 87 0.020
negative regulation of leukocyte differentiation GO:1902106 24 0.020
apoptotic signaling pathway GO:0097190 268 0.020
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
ribonucleoside monophosphate metabolic process GO:0009161 187 0.020
protein processing GO:0016485 226 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.019
negative regulation of immune system process GO:0002683 136 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
spermatid differentiation GO:0048515 4 0.019
single organism cellular localization GO:1902580 332 0.019
lipid biosynthetic process GO:0008610 177 0.019
positive regulation of transport GO:0051050 336 0.019
negative regulation of cell growth GO:0030308 83 0.019
receptor mediated endocytosis GO:0006898 84 0.019
positive regulation of cell death GO:0010942 263 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
positive regulation of dna metabolic process GO:0051054 73 0.018
cell cycle g1 s phase transition GO:0044843 80 0.018
embryo development GO:0009790 123 0.018
mitotic dna damage checkpoint GO:0044773 28 0.018
locomotory behavior GO:0007626 1 0.018
regulation of mapk cascade GO:0043408 262 0.018
limbic system development GO:0021761 3 0.018
negative regulation of protein maturation GO:1903318 142 0.018
negative regulation of kinase activity GO:0033673 106 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
mitotic cell cycle checkpoint GO:0007093 68 0.018
peptidyl tyrosine phosphorylation GO:0018108 170 0.018
positive regulation of phosphorylation GO:0042327 394 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
regulation of actin filament based process GO:0032970 141 0.017
neuromuscular junction development GO:0007528 3 0.017
intracellular protein transport GO:0006886 270 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
regulation of myeloid leukocyte differentiation GO:0002761 39 0.017
regulation of protein stability GO:0031647 87 0.017
ectoderm development GO:0007398 3 0.017
epithelial cell differentiation GO:0030855 141 0.017
memory GO:0007613 3 0.017
dna replication GO:0006260 116 0.016
protein localization to nucleus GO:0034504 136 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.016
protein methylation GO:0006479 74 0.016
cation transport GO:0006812 331 0.016
negative regulation of protein kinase activity GO:0006469 98 0.016
immune system development GO:0002520 195 0.016
immune response GO:0006955 307 0.016
actin cytoskeleton organization GO:0030036 207 0.016
positive regulation of intracellular transport GO:0032388 104 0.016
glial cell migration GO:0008347 4 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
positive regulation of organelle organization GO:0010638 195 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
oxidation reduction process GO:0055114 396 0.016
peripheral nervous system development GO:0007422 2 0.016
nervous system development GO:0007399 293 0.016
purine nucleoside catabolic process GO:0006152 398 0.015
regulation of meiotic cell cycle GO:0051445 4 0.015
positive regulation of catabolic process GO:0009896 310 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
double strand break repair GO:0006302 101 0.015
small molecule biosynthetic process GO:0044283 157 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
negative regulation of transferase activity GO:0051348 124 0.015
myeloid cell differentiation GO:0030099 117 0.015
cytokinesis GO:0000910 96 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
maintenance of location GO:0051235 112 0.015
regulation of response to dna damage stimulus GO:2001020 94 0.015
transmembrane transport GO:0055085 399 0.014
hindbrain development GO:0030902 3 0.014
protein deubiquitination GO:0016579 79 0.014
cellular component morphogenesis GO:0032989 314 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
g1 s transition of mitotic cell cycle GO:0000082 78 0.014
system process GO:0003008 349 0.014
secretion GO:0046903 254 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
adult locomotory behavior GO:0008344 1 0.014
negative regulation of cellular component movement GO:0051271 106 0.014
regulation of actin cytoskeleton organization GO:0032956 116 0.014
cellular protein complex assembly GO:0043623 188 0.014
negative regulation of cell motility GO:2000146 104 0.014
secretion by cell GO:0032940 226 0.014
membrane organization GO:0061024 292 0.014
single organism reproductive process GO:0044702 98 0.014
cell projection organization GO:0030030 252 0.014
protein localization to membrane GO:0072657 160 0.014
cell projection morphogenesis GO:0048858 129 0.014
macromolecule methylation GO:0043414 97 0.014
oogenesis GO:0048477 2 0.013
organic acid biosynthetic process GO:0016053 97 0.013
positive regulation of proteolysis GO:0045862 142 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
cellular lipid metabolic process GO:0044255 303 0.013
sister chromatid segregation GO:0000819 54 0.013
cell division GO:0051301 168 0.013
regulation of intracellular transport GO:0032386 195 0.013
protein import into nucleus GO:0006606 104 0.013
regulation of cellular response to stress GO:0080135 244 0.013
nerve development GO:0021675 4 0.013
cell cycle arrest GO:0007050 71 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
reproductive process GO:0022414 106 0.013
spermatid development GO:0007286 4 0.013
spinal cord development GO:0021510 4 0.013
atp catabolic process GO:0006200 157 0.013
rho protein signal transduction GO:0007266 26 0.013
actin filament organization GO:0007015 128 0.013
positive regulation of cell differentiation GO:0045597 211 0.012
regulation of cell adhesion GO:0030155 166 0.012
intracellular mrna localization GO:0008298 1 0.012
gtp metabolic process GO:0046039 239 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
innate immune response GO:0045087 178 0.012
regeneration GO:0031099 4 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
peptidyl lysine modification GO:0018205 144 0.012
positive regulation of developmental process GO:0051094 314 0.012
hippocampus development GO:0021766 1 0.012
endocytosis GO:0006897 159 0.012
dna packaging GO:0006323 77 0.012
lens development in camera type eye GO:0002088 2 0.012
single organism cell adhesion GO:0098602 179 0.012
negative regulation of transport GO:0051051 176 0.012
response to hormone GO:0009725 175 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
dephosphorylation GO:0016311 209 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
actin filament based movement GO:0030048 17 0.012
cell cell signaling GO:0007267 155 0.012
protein stabilization GO:0050821 64 0.012
positive regulation of cell migration GO:0030335 172 0.012
t cell differentiation in thymus GO:0033077 4 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
protein localization to organelle GO:0033365 280 0.012
histone methylation GO:0016571 60 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
single organism membrane organization GO:0044802 268 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
regulation of response to external stimulus GO:0032101 222 0.012
tissue regeneration GO:0042246 3 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
protein polyubiquitination GO:0000209 110 0.011
regulation of peptidase activity GO:0052547 180 0.011
negative regulation of organelle organization GO:0010639 126 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
rhythmic behavior GO:0007622 2 0.011
negative regulation of cellular protein catabolic process GO:1903363 38 0.011
hippo signaling GO:0035329 20 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
negative regulation of locomotion GO:0040013 118 0.011
motor neuron axon guidance GO:0008045 2 0.011
compound eye development GO:0048749 1 0.011
neurogenesis GO:0022008 169 0.011
central nervous system development GO:0007417 123 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
regulation of dna replication GO:0006275 68 0.011
endomembrane system organization GO:0010256 196 0.011
tripartite regional subdivision GO:0007351 2 0.011
regulation of carbohydrate metabolic process GO:0006109 54 0.011
organelle assembly GO:0070925 176 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
sequestering of metal ion GO:0051238 24 0.011
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.011
visual behavior GO:0007632 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 98 0.011
positive regulation of intracellular protein transport GO:0090316 76 0.011
regulation of cell development GO:0060284 161 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
positive regulation of nfat protein import into nucleus GO:0051533 3 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
cell projection assembly GO:0030031 126 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
regulation of peptidyl serine phosphorylation GO:0033135 50 0.011
rna interference GO:0016246 4 0.011
inner ear morphogenesis GO:0042472 4 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
positive regulation of immune system process GO:0002684 283 0.010
associative learning GO:0008306 1 0.010
neurotransmitter secretion GO:0007269 4 0.010
anterior posterior axis specification embryo GO:0008595 2 0.010
monosaccharide metabolic process GO:0005996 74 0.010
tube development GO:0035295 125 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.010
single organism nuclear import GO:1902593 104 0.010
methylation GO:0032259 106 0.010
cell activation GO:0001775 213 0.010
nucleosome organization GO:0034728 66 0.010
neurological system process GO:0050877 163 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
positive regulation of dna replication GO:0045740 35 0.010
anterior posterior axis specification GO:0009948 2 0.010
myosin filament assembly GO:0031034 2 0.010
ion transmembrane transport GO:0034220 338 0.010
protein localization to plasma membrane GO:0072659 93 0.010
stress fiber assembly GO:0043149 40 0.010
metal ion transport GO:0030001 272 0.010
long term memory GO:0007616 2 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.010
positive regulation of cytokine production GO:0001819 167 0.010
regulation of dna repair GO:0006282 47 0.010
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010

VPRBP disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.029
disease of cellular proliferation DOID:14566 174 0.029
organ system cancer DOID:0050686 164 0.029
sensory system disease DOID:0050155 203 0.024
nervous system disease DOID:863 431 0.024
eye and adnexa disease DOID:1492 150 0.024
eye disease DOID:5614 149 0.024
disease of metabolism DOID:0014667 295 0.019
inherited metabolic disorder DOID:655 242 0.017
musculoskeletal system disease DOID:17 223 0.016
retinal disease DOID:5679 118 0.013
central nervous system disease DOID:331 186 0.013
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
myopathy DOID:423 104 0.010