Homo sapiens

8 known processes

GNS

glucosamine (N-acetyl)-6-sulfatase

(Aliases: G6S,MGC21274)

GNS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
natural killer cell activation involved in immune response GO:0002323 2 0.783
cellular chemical homeostasis GO:0055082 180 0.283
intracellular protein transport GO:0006886 270 0.270
protein localization to organelle GO:0033365 280 0.240
cellular amide metabolic process GO:0043603 69 0.194
regulation of peptidase activity GO:0052547 180 0.192
lysosomal transport GO:0007041 33 0.173
cellular homeostasis GO:0019725 196 0.166
regulation of exocytosis GO:0017157 46 0.165
cellular ion homeostasis GO:0006873 168 0.164
regulation of cell motility GO:2000145 299 0.145
Human
natural killer cell degranulation GO:0043320 2 0.128
post embryonic development GO:0009791 2 0.127
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.120
cytoplasmic transport GO:0016482 379 0.118
determination of adult lifespan GO:0008340 2 0.112
ion homeostasis GO:0050801 230 0.111
apoptotic signaling pathway GO:0097190 268 0.110
neuromuscular process controlling balance GO:0050885 7 0.100
immune response GO:0006955 307 0.100
regulation of defense response GO:0031347 154 0.098
memory GO:0007613 3 0.097
exocytosis GO:0006887 71 0.095
regulation of mapk cascade GO:0043408 262 0.090
female gamete generation GO:0007292 2 0.087
system process GO:0003008 349 0.086
multicellular organismal aging GO:0010259 3 0.086
signal transduction by phosphorylation GO:0023014 297 0.083
drug transmembrane transport GO:0006855 7 0.080
positive regulation of immune response GO:0050778 159 0.078
positive regulation of natural killer cell activation GO:0032816 8 0.077
cation homeostasis GO:0055080 189 0.073
mating GO:0007618 1 0.070
establishment of protein localization to organelle GO:0072594 172 0.067
peptide metabolic process GO:0006518 51 0.064
oogenesis GO:0048477 2 0.064
mapk cascade GO:0000165 288 0.063
lipid metabolic process GO:0006629 381 0.062
long term memory GO:0007616 2 0.061
positive regulation of immune system process GO:0002684 283 0.060
granzyme mediated apoptotic signaling pathway GO:0008626 4 0.060
protein maturation GO:0051604 233 0.059
positive regulation of defense response GO:0031349 87 0.059
divalent inorganic cation homeostasis GO:0072507 136 0.059
cellular amino acid metabolic process GO:0006520 116 0.059
vacuolar transport GO:0007034 34 0.058
carbohydrate metabolic process GO:0005975 207 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.056
cellular cation homeostasis GO:0030003 163 0.056
regulation of protein maturation GO:1903317 150 0.055
chemical homeostasis GO:0048878 306 0.055
negative regulation of hydrolase activity GO:0051346 182 0.054
sphingolipid metabolic process GO:0006665 38 0.053
endosomal transport GO:0016197 129 0.053
positive regulation of exocytosis GO:0045921 35 0.052
innate immune response GO:0045087 178 0.051
protein catabolic process GO:0030163 325 0.050
negative regulation of peptidase activity GO:0010466 91 0.050
positive regulation of transport GO:0051050 336 0.050
cellular metal ion homeostasis GO:0006875 146 0.049
locomotory behavior GO:0007626 1 0.047
negative regulation of intracellular signal transduction GO:1902532 183 0.046
regulation of intracellular transport GO:0032386 195 0.046
positive regulation of phosphorylation GO:0042327 394 0.046
growth GO:0040007 202 0.044
hormone metabolic process GO:0042445 61 0.044
vacuole organization GO:0007033 44 0.044
ganglioside catabolic process GO:0006689 3 0.044
post golgi vesicle mediated transport GO:0006892 36 0.043
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.043
response to cytokine GO:0034097 232 0.042
negative regulation of multicellular organismal process GO:0051241 317 0.042
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.041
Human
metal ion homeostasis GO:0055065 169 0.041
response to axon injury GO:0048678 1 0.040
neuromuscular process GO:0050905 15 0.040
regulation of immune response GO:0050776 201 0.040
negative regulation of glycoprotein metabolic process GO:1903019 8 0.040
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.039
blood vessel morphogenesis GO:0048514 162 0.039
Human
regulation of cell activation GO:0050865 125 0.038
protein processing GO:0016485 226 0.038
regulation of cellular response to stress GO:0080135 244 0.037
natural killer cell activation GO:0030101 12 0.037
regulation of lymphocyte activation GO:0051249 103 0.036
regulation of protein localization GO:0032880 296 0.035
regulation of secretion by cell GO:1903530 177 0.035
vasculature development GO:0001944 181 0.035
Human
cellular divalent inorganic cation homeostasis GO:0072503 128 0.034
lymphocyte mediated immunity GO:0002449 48 0.033
calcium ion homeostasis GO:0055074 122 0.033
positive regulation of mapk cascade GO:0043410 190 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
regulation of cellular component movement GO:0051270 334 0.032
Human
leukocyte activation GO:0045321 164 0.032
eye pigmentation GO:0048069 1 0.032
positive regulation of leukocyte degranulation GO:0043302 3 0.032
lipid catabolic process GO:0016042 84 0.031
regulation of secretion GO:0051046 194 0.031
neurological system process GO:0050877 163 0.031
regulation of cytokine production GO:0001817 232 0.031
regulation of innate immune response GO:0045088 97 0.031
negative regulation of proteolysis GO:0045861 132 0.030
regulation of protein stability GO:0031647 87 0.030
single organism carbohydrate metabolic process GO:0044723 193 0.030
regeneration GO:0031099 4 0.030
immune system development GO:0002520 195 0.030
cell activation GO:0001775 213 0.030
secretion GO:0046903 254 0.029
negative regulation of protein processing GO:0010955 142 0.029
regulation of angiotensin levels in blood GO:0002002 3 0.028
golgi to lysosome transport GO:0090160 3 0.028
peripheral nervous system development GO:0007422 2 0.028
protein stabilization GO:0050821 64 0.028
reproductive process GO:0022414 106 0.028
negative regulation of protein metabolic process GO:0051248 391 0.027
regulation of protein catabolic process GO:0042176 155 0.027
response to bacterium GO:0009617 144 0.027
inorganic cation transmembrane transport GO:0098662 194 0.027
positive regulation of lymphocyte activation GO:0051251 73 0.026
posttranscriptional regulation of gene expression GO:0010608 213 0.026
cellular calcium ion homeostasis GO:0006874 117 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
positive regulation of cell motility GO:2000147 177 0.026
negative regulation of trophoblast cell migration GO:1901164 3 0.026
lipid localization GO:0010876 106 0.026
response to oxidative stress GO:0006979 121 0.026
natural killer cell mediated immunity GO:0002228 23 0.026
lysosome organization GO:0007040 24 0.025
ceramide metabolic process GO:0006672 25 0.025
organophosphate biosynthetic process GO:0090407 163 0.025
ion transmembrane transport GO:0034220 338 0.025
secretion by cell GO:0032940 226 0.024
maintenance of location GO:0051235 112 0.024
defense response GO:0006952 315 0.024
regulation of natural killer cell mediated immunity GO:0002715 16 0.024
single organism reproductive process GO:0044702 98 0.023
regulation of natural killer cell activation GO:0032814 9 0.023
negative regulation of cell differentiation GO:0045596 171 0.023
myeloid cell differentiation GO:0030099 117 0.023
regulation of amyloid precursor protein biosynthetic process GO:0042984 4 0.023
endocrine process GO:0050886 25 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
regulation of lipid metabolic process GO:0019216 96 0.023
protein targeting GO:0006605 187 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.022
ganglioside metabolic process GO:0001573 7 0.022
negative regulation of blood pressure GO:0045776 3 0.022
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 11 0.022
single organism carbohydrate catabolic process GO:0044724 33 0.022
enzyme linked receptor protein signaling pathway GO:0007167 303 0.022
Human
positive regulation of cytokine production GO:0001819 167 0.021
response to wounding GO:0009611 168 0.021
cell death in response to oxidative stress GO:0036473 29 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
n acetylglucosamine metabolic process GO:0006044 7 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
response to endoplasmic reticulum stress GO:0034976 49 0.021
transmembrane transport GO:0055085 399 0.020
golgi to vacuole transport GO:0006896 3 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
regulation of cell cycle GO:0051726 393 0.020
cellular response to hormone stimulus GO:0032870 125 0.020
establishment of planar polarity GO:0001736 3 0.020
vesicle mediated transport GO:0016192 371 0.020
regulation of cell migration GO:0030334 289 0.019
Human
anatomical structure homeostasis GO:0060249 100 0.019
regulation of locomotion GO:0040012 329 0.019
Human
wnt signaling pathway GO:0016055 156 0.019
Human
cytoskeleton dependent intracellular transport GO:0030705 21 0.019
head development GO:0060322 108 0.019
circulatory system development GO:0072359 262 0.019
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
carbohydrate catabolic process GO:0016052 36 0.019
hemopoiesis GO:0030097 180 0.019
epithelial cell differentiation GO:0030855 141 0.019
liposaccharide metabolic process GO:1903509 27 0.019
regulation of wnt signaling pathway GO:0030111 123 0.018
Human
positive regulation of cell migration GO:0030335 172 0.018
regulation of proteolysis GO:0030162 293 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
natural killer cell mediated cytotoxicity GO:0042267 23 0.018
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.018
blastoderm segmentation GO:0007350 2 0.018
leukocyte mediated immunity GO:0002443 59 0.018
cellular response to reactive oxygen species GO:0034614 50 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.017
regulation of cell differentiation GO:0045595 393 0.017
positive regulation of secretion GO:0051047 116 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
regulation of blood pressure GO:0008217 30 0.017
regulation of leukocyte mediated immunity GO:0002703 38 0.016
monovalent inorganic cation transport GO:0015672 128 0.016
cell morphogenesis GO:0000902 296 0.016
positive regulation of cell cycle GO:0045787 140 0.016
cell substrate adhesion GO:0031589 132 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
single organism cellular localization GO:1902580 332 0.016
immune effector process GO:0002252 159 0.016
regulation of protein secretion GO:0050708 86 0.016
negative regulation of cell development GO:0010721 48 0.016
epithelial cell proliferation GO:0050673 128 0.016
Human
regulation of growth GO:0040008 165 0.015
membrane lipid metabolic process GO:0006643 53 0.015
neural tube patterning GO:0021532 2 0.015
regulation of angiotensin metabolic process GO:0060177 3 0.015
endomembrane system organization GO:0010256 196 0.015
membrane protein proteolysis GO:0033619 38 0.015
cell type specific apoptotic process GO:0097285 125 0.015
transition metal ion homeostasis GO:0055076 31 0.015
regulation of receptor activity GO:0010469 47 0.015
biological adhesion GO:0022610 331 0.015
positive regulation of secretion by cell GO:1903532 108 0.015
regulation of hormone levels GO:0010817 125 0.015
circulatory system process GO:0003013 113 0.015
alcohol metabolic process GO:0006066 114 0.015
response to thyroid hormone GO:0097066 9 0.015
positive regulation of endopeptidase activity GO:0010950 84 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
positive regulation of cell activation GO:0050867 81 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
behavior GO:0007610 112 0.014
cellular component morphogenesis GO:0032989 314 0.014
embryo development GO:0009790 123 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.014
cellular response to thyroid hormone stimulus GO:0097067 9 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
tissue regeneration GO:0042246 3 0.014
response to oxygen containing compound GO:1901700 369 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
prostate gland development GO:0030850 3 0.014
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.014
regulation of microtubule based process GO:0032886 74 0.014
response to hormone GO:0009725 175 0.014
neuron projection regeneration GO:0031102 1 0.014
angiotensin maturation GO:0002003 2 0.014
transmission of nerve impulse GO:0019226 11 0.014
negative regulation of catabolic process GO:0009895 104 0.014
negative regulation of cell death GO:0060548 345 0.014
transition metal ion transport GO:0000041 23 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
angiogenesis GO:0001525 147 0.013
Human
regulation of glycoprotein biosynthetic process GO:0010559 14 0.013
protein homooligomerization GO:0051260 100 0.013
cellular amine metabolic process GO:0044106 41 0.013
response to nitrogen compound GO:1901698 184 0.013
cytokine production GO:0001816 247 0.013
regulation of membrane potential GO:0042391 95 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
lytic vacuole organization GO:0080171 24 0.013
lipid translocation GO:0034204 2 0.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.013
regulation of osteoblast differentiation GO:0045667 38 0.013
amine metabolic process GO:0009308 44 0.013
cellular response to external stimulus GO:0071496 111 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
cellular lipid catabolic process GO:0044242 65 0.013
cellular ketone metabolic process GO:0042180 80 0.013
oligosaccharide metabolic process GO:0009311 13 0.013
regulation of vasodilation GO:0042312 4 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 26 0.013
amyloid precursor protein metabolic process GO:0042982 17 0.012
leukocyte differentiation GO:0002521 98 0.012
positive regulation of leukocyte mediated immunity GO:0002705 24 0.012
leukocyte degranulation GO:0043299 11 0.012
positive regulation of innate immune response GO:0045089 79 0.012
cellular response to oxidative stress GO:0034599 85 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
myeloid leukocyte differentiation GO:0002573 60 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
lymphocyte activation GO:0046649 133 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
negative regulation of protein maturation GO:1903318 142 0.012
skeletal system development GO:0001501 79 0.012
phospholipid translocation GO:0045332 2 0.012
regulation of immune effector process GO:0002697 91 0.012
transforming growth factor beta1 production GO:0032905 3 0.012
receptor metabolic process GO:0043112 81 0.012
purine containing compound catabolic process GO:0072523 411 0.011
positive regulation of cell death GO:0010942 263 0.011
oocyte development GO:0048599 1 0.011
negative regulation of vasculature development GO:1901343 43 0.011
Human
regulation of protein processing GO:0070613 150 0.011
action potential GO:0001508 34 0.011
cell killing GO:0001906 34 0.011
cellular component disassembly GO:0022411 92 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
epithelium development GO:0060429 227 0.011
response to organic cyclic compound GO:0014070 204 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
Human
regulation of cell development GO:0060284 161 0.011
regulation of lymphocyte mediated immunity GO:0002706 33 0.011
positive regulation of developmental process GO:0051094 314 0.011
negative regulation of cell cycle GO:0045786 193 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
ossification GO:0001503 121 0.010
positive regulation of epithelial cell proliferation GO:0050679 65 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
glial cell migration GO:0008347 4 0.010
nuclear transport GO:0051169 179 0.010
protein localization to membrane GO:0072657 160 0.010
cell growth GO:0016049 160 0.010
tissue homeostasis GO:0001894 63 0.010
cellular modified amino acid metabolic process GO:0006575 64 0.010
notch signaling pathway GO:0007219 31 0.010
response to biotic stimulus GO:0009607 276 0.010
negative regulation of locomotion GO:0040013 118 0.010
Human
cellular response to endogenous stimulus GO:0071495 336 0.010
Human
cell migration involved in gastrulation GO:0042074 1 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.010
cation transmembrane transport GO:0098655 238 0.010
positive regulation of intracellular protein transport GO:0090316 76 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
positive regulation of locomotion GO:0040017 186 0.010

GNS disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.966
lysosomal storage disease DOID:3211 47 0.966
inherited metabolic disorder DOID:655 242 0.966
lipid storage disease DOID:9455 28 0.941
cerebral degeneration DOID:1443 16 0.801
central nervous system disease DOID:331 186 0.801
brain disease DOID:936 73 0.801
nervous system disease DOID:863 431 0.801
epilepsy syndrome DOID:1826 41 0.485
variable age at onset electroclinical syndrome DOID:0050706 8 0.485
electroclinical syndrome DOID:0050701 32 0.485
progressive myoclonus epilepsy DOID:891 8 0.485
neuronal ceroid lipofuscinosis DOID:14503 11 0.102
musculoskeletal system disease DOID:17 223 0.077
connective tissue disease DOID:65 109 0.077
bone disease DOID:0080001 88 0.069
disease of cellular proliferation DOID:14566 174 0.061
cancer DOID:162 167 0.051
sphingolipidosis DOID:1927 14 0.029
leukodystrophy DOID:10579 8 0.025
acquired metabolic disease DOID:0060158 58 0.021
immune system disease DOID:2914 155 0.020
disease of mental health DOID:150 70 0.012
cognitive disorder DOID:1561 29 0.012
organ system cancer DOID:0050686 164 0.012
mucopolysaccharidosis DOID:12798 11 0.002
mucopolysaccharidosis iii DOID:12801 4 0.000