Homo sapiens

84 known processes

PELP1

proline, glutamate and leucine rich protein 1

(Aliases: MNAR,HMX3,P160)

PELP1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
central nervous system projection neuron axonogenesis GO:0021952 3 0.734
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.670
toll signaling pathway GO:0008063 2 0.599
ribosomal large subunit biogenesis GO:0042273 10 0.450
response to wounding GO:0009611 168 0.354
defense response GO:0006952 315 0.326
single organism cellular localization GO:1902580 332 0.299
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.294
regulation of protein localization GO:0032880 296 0.281
ncrna metabolic process GO:0034660 108 0.277
negative regulation of toll signaling pathway GO:0045751 1 0.272
determination of adult lifespan GO:0008340 2 0.262
histone modification GO:0016570 251 0.255
positive regulation of apoptotic process GO:0043065 246 0.210
regulation of inflammatory response GO:0050727 46 0.203
activation of cysteine type endopeptidase activity GO:0097202 57 0.194
regulation of toll signaling pathway GO:0008592 1 0.192
protein maturation GO:0051604 233 0.189
secretion GO:0046903 254 0.187
zymogen activation GO:0031638 70 0.175
cytoplasmic transport GO:0016482 379 0.174
ncrna processing GO:0034470 83 0.170
negative regulation of response to wounding GO:1903035 47 0.169
regulation of response to external stimulus GO:0032101 222 0.169
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.153
multicellular organismal aging GO:0010259 3 0.150
regulation of defense response GO:0031347 154 0.147
protein desumoylation GO:0016926 4 0.143
regulation of response to wounding GO:1903034 101 0.141
regulation of dna metabolic process GO:0051052 153 0.139
chromatin organization GO:0006325 351 0.129
protein dna complex assembly GO:0065004 64 0.121
atp metabolic process GO:0046034 176 0.121
central nervous system neuron axonogenesis GO:0021955 3 0.117
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.115
positive regulation of peptidase activity GO:0010952 88 0.114
dendritic spine morphogenesis GO:0060997 3 0.111
post embryonic development GO:0009791 2 0.110
macromolecule methylation GO:0043414 97 0.108
response to oxygen levels GO:0070482 100 0.106
regulation of cell cycle GO:0051726 393 0.099
inflammatory response GO:0006954 79 0.094
ribonucleoprotein complex subunit organization GO:0071826 81 0.094
positive regulation of cell death GO:0010942 263 0.093
secretion by cell GO:0032940 226 0.092
positive regulation of endopeptidase activity GO:0010950 84 0.081
cellular macromolecular complex assembly GO:0034622 324 0.081
cell morphogenesis GO:0000902 296 0.080
central nervous system development GO:0007417 123 0.079
rrna metabolic process GO:0016072 40 0.079
establishment of protein localization to organelle GO:0072594 172 0.077
response to abiotic stimulus GO:0009628 336 0.076
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.076
mitotic cell cycle process GO:1903047 286 0.073
negative regulation of programmed cell death GO:0043069 321 0.068
response to oxygen containing compound GO:1901700 369 0.068
protein ubiquitination GO:0016567 314 0.066
regulation of cell motility GO:2000145 299 0.066
receptor mediated endocytosis GO:0006898 84 0.065
regulation of endopeptidase activity GO:0052548 170 0.063
regulation of establishment of protein localization GO:0070201 242 0.061
methylation dependent chromatin silencing GO:0006346 3 0.061
negative regulation of defense response GO:0031348 47 0.060
dna repair GO:0006281 198 0.059
cellular response to decreased oxygen levels GO:0036294 51 0.058
positive regulation of programmed cell death GO:0043068 249 0.057
endocytosis GO:0006897 159 0.057
positive regulation of cell motility GO:2000147 177 0.056
response to genistein GO:0033595 1 0.055
nervous system development GO:0007399 293 0.054
dna dependent dna replication GO:0006261 44 0.054
positive regulation of cell proliferation GO:0008284 301 0.054
positive regulation of immune system process GO:0002684 283 0.052
regulation of cellular component movement GO:0051270 334 0.052
regulation of peptidase activity GO:0052547 180 0.052
cellular response to hypoxia GO:0071456 51 0.051
positive regulation of proteolysis GO:0045862 142 0.050
response to organic cyclic compound GO:0014070 204 0.050
negative regulation of response to external stimulus GO:0032102 83 0.050
protein localization to organelle GO:0033365 280 0.049
protein dna complex subunit organization GO:0071824 80 0.049
dendritic spine organization GO:0097061 4 0.047
cellular response to oxygen levels GO:0071453 55 0.047
hindbrain development GO:0030902 3 0.046
positive regulation of hydrolase activity GO:0051345 331 0.046
regulation of mitotic cell cycle phase transition GO:1901990 118 0.046
positive regulation of cellular component movement GO:0051272 181 0.045
metencephalon development GO:0022037 2 0.045
dna packaging GO:0006323 77 0.044
response to biotic stimulus GO:0009607 276 0.043
positive regulation of locomotion GO:0040017 186 0.043
negative regulation of cell death GO:0060548 345 0.040
methylation GO:0032259 106 0.039
membrane organization GO:0061024 292 0.039
epidermis development GO:0008544 59 0.039
epidermis morphogenesis GO:0048730 3 0.039
cell projection morphogenesis GO:0048858 129 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
oxidation reduction process GO:0055114 396 0.038
histone methylation GO:0016571 60 0.038
segmentation GO:0035282 4 0.037
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.037
regulation of locomotion GO:0040012 329 0.037
dna replication GO:0006260 116 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.036
response to decreased oxygen levels GO:0036293 96 0.036
innate immune response GO:0045087 178 0.036
mitotic cell cycle GO:0000278 326 0.035
protein targeting GO:0006605 187 0.035
protein processing GO:0016485 226 0.035
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.035
maturation of lsu rrna GO:0000470 3 0.035
cellular ketone metabolic process GO:0042180 80 0.035
cell projection organization GO:0030030 252 0.035
regulation of proteasomal protein catabolic process GO:0061136 87 0.035
proteasomal protein catabolic process GO:0010498 176 0.035
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.035
chromatin modification GO:0016568 298 0.034
regulation of dna replication GO:0006275 68 0.034
positive regulation of transport GO:0051050 336 0.034
intracellular receptor signaling pathway GO:0030522 104 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.033
negative regulation of cellular component organization GO:0051129 235 0.033
ribonucleoprotein complex assembly GO:0022618 78 0.033
cellular protein catabolic process GO:0044257 261 0.032
rna processing GO:0006396 255 0.032
cellular response to dna damage stimulus GO:0006974 379 0.032
negative regulation of inflammatory response GO:0050728 22 0.032
cell morphogenesis involved in differentiation GO:0000904 144 0.032
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.031
response to other organism GO:0051707 261 0.031
regulation of cysteine type endopeptidase activity GO:2000116 127 0.031
dna conformation change GO:0071103 113 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
regulation of protein transport GO:0051223 213 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
covalent chromatin modification GO:0016569 254 0.030
protein modification by small protein removal GO:0070646 92 0.030
cellular macromolecule catabolic process GO:0044265 380 0.029
ameboidal type cell migration GO:0001667 135 0.029
positive regulation of cell migration GO:0030335 172 0.029
purine nucleoside monophosphate catabolic process GO:0009128 158 0.029
positive regulation of gliogenesis GO:0014015 4 0.028
single organism membrane organization GO:0044802 268 0.028
dephosphorylation GO:0016311 209 0.028
biological adhesion GO:0022610 331 0.028
immune response GO:0006955 307 0.028
protein acetylation GO:0006473 116 0.028
embryonic placenta development GO:0001892 1 0.028
locomotory behavior GO:0007626 1 0.028
regulation of homeostatic process GO:0032844 121 0.027
response to external biotic stimulus GO:0043207 261 0.027
response to nitrogen compound GO:1901698 184 0.026
regulation of protein autoubiquitination GO:1902498 3 0.026
regulation of cell migration GO:0030334 289 0.026
spermatid differentiation GO:0048515 4 0.025
nuclear transport GO:0051169 179 0.025
modification dependent macromolecule catabolic process GO:0043632 212 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.025
negative regulation of cell cycle process GO:0010948 121 0.025
rrna processing GO:0006364 35 0.024
mitochondrion organization GO:0007005 156 0.024
cell fate determination GO:0001709 3 0.024
growth GO:0040007 202 0.024
atp catabolic process GO:0006200 157 0.023
response to interferon gamma GO:0034341 39 0.023
negative regulation of protein transport GO:0051224 75 0.023
embryonic hemopoiesis GO:0035162 4 0.023
cell cycle dna replication GO:0044786 11 0.023
regulation of intracellular transport GO:0032386 195 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023
limbic system development GO:0021761 3 0.022
chromosome segregation GO:0007059 114 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
organelle assembly GO:0070925 176 0.022
wnt signaling pathway GO:0016055 156 0.022
tissue regeneration GO:0042246 3 0.022
determination of left right symmetry GO:0007368 11 0.022
intracellular protein transport GO:0006886 270 0.021
pituitary gland development GO:0021983 2 0.021
determination of bilateral symmetry GO:0009855 15 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
protein localization to membrane GO:0072657 160 0.021
regeneration GO:0031099 4 0.021
microtubule organizing center organization GO:0031023 62 0.020
dendrite morphogenesis GO:0048813 14 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
neuron differentiation GO:0030182 138 0.020
cell part morphogenesis GO:0032990 137 0.020
regulation of kinase activity GO:0043549 314 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
cilium morphogenesis GO:0060271 75 0.019
blastoderm segmentation GO:0007350 2 0.019
peptidyl lysine modification GO:0018205 144 0.019
female gamete generation GO:0007292 2 0.019
protein autoubiquitination GO:0051865 37 0.019
regulation of protein processing GO:0070613 150 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
interspecies interaction between organisms GO:0044419 156 0.019
tissue migration GO:0090130 119 0.019
amine metabolic process GO:0009308 44 0.019
cell development GO:0048468 328 0.019
nucleosome assembly GO:0006334 50 0.019
protein catabolic process GO:0030163 325 0.019
protein alkylation GO:0008213 74 0.018
negative regulation of chromosome organization GO:2001251 48 0.018
tongue development GO:0043586 1 0.018
positive regulation of cell differentiation GO:0045597 211 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
histone lysine methylation GO:0034968 50 0.018
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.018
pattern specification process GO:0007389 43 0.018
chromatin assembly GO:0031497 61 0.018
cellular amine metabolic process GO:0044106 41 0.018
nucleoside catabolic process GO:0009164 408 0.017
positive regulation of protein ubiquitination GO:0031398 53 0.017
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.017
response to lipopolysaccharide GO:0032496 70 0.017
single organism nuclear import GO:1902593 104 0.017
cellular amino acid metabolic process GO:0006520 116 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
neurological system process GO:0050877 163 0.017
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.017
response to molecule of bacterial origin GO:0002237 82 0.016
central nervous system neuron development GO:0021954 7 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
response to nutrient levels GO:0031667 81 0.016
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.016
maturation of ssu rrna GO:0030490 3 0.016
cerebellum development GO:0021549 2 0.016
regulation of immune response GO:0050776 201 0.016
sensory perception of mechanical stimulus GO:0050954 37 0.016
cellular response to nitrogen compound GO:1901699 144 0.016
circadian behavior GO:0048512 2 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
vitamin d receptor signaling pathway GO:0070561 4 0.016
apoptotic signaling pathway GO:0097190 268 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
skin development GO:0043588 76 0.016
epithelial cell migration GO:0010631 119 0.015
histone demethylation GO:0016577 15 0.015
protein import GO:0017038 130 0.015
regulation of protein maturation GO:1903317 150 0.015
rhythmic behavior GO:0007622 2 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
response to fungus GO:0009620 4 0.015
brain development GO:0007420 97 0.015
microtubule based process GO:0007017 210 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
protein oligomerization GO:0051259 173 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
actin filament based movement GO:0030048 17 0.015
carbohydrate metabolic process GO:0005975 207 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.014
protein methylation GO:0006479 74 0.014
response to extracellular stimulus GO:0009991 85 0.014
dendritic spine development GO:0060996 6 0.014
regulation of protein targeting GO:1903533 91 0.014
response to bacterium GO:0009617 144 0.014
cristae formation GO:0042407 3 0.014
regulation of proteolysis GO:0030162 293 0.014
inner ear morphogenesis GO:0042472 4 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
regulation of cell cycle process GO:0010564 266 0.014
regulation of myeloid cell differentiation GO:0045637 81 0.014
macromolecule deacylation GO:0098732 41 0.014
protein targeting to membrane GO:0006612 42 0.013
memory GO:0007613 3 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
stem cell differentiation GO:0048863 93 0.013
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.013
ribosome biogenesis GO:0042254 48 0.013
positive regulation of protein autoubiquitination GO:1902499 2 0.013
thymus development GO:0048538 3 0.013
dna replication independent nucleosome assembly GO:0006336 27 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
oogenesis GO:0048477 2 0.013
specification of symmetry GO:0009799 16 0.013
protein secretion GO:0009306 98 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
myeloid cell homeostasis GO:0002262 34 0.013
regulation of ribonuclease activity GO:0060700 3 0.013
centrosome cycle GO:0007098 32 0.013
system process GO:0003008 349 0.013
head development GO:0060322 108 0.013
regulation of protein catabolic process GO:0042176 155 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.012
nucleotide catabolic process GO:0009166 408 0.012
demethylation GO:0070988 37 0.012
response to inorganic substance GO:0010035 127 0.012
myeloid cell differentiation GO:0030099 117 0.012
axis elongation GO:0003401 4 0.012
somitogenesis GO:0001756 2 0.012
vesicle mediated transport GO:0016192 371 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
multi organism reproductive process GO:0044703 54 0.012
regionalization GO:0003002 29 0.012
hair follicle morphogenesis GO:0031069 2 0.012
positive regulation of transferase activity GO:0051347 227 0.012
nucleosome organization GO:0034728 66 0.012
negative regulation of transport GO:0051051 176 0.012
protein stabilization GO:0050821 64 0.012
tube closure GO:0060606 3 0.012
response to radiation GO:0009314 151 0.012
actin mediated cell contraction GO:0070252 12 0.012
vesicle organization GO:0016050 62 0.012
protein dealkylation GO:0008214 17 0.012
cell cycle g2 m phase transition GO:0044839 43 0.012
epithelium migration GO:0090132 119 0.012
neuron development GO:0048666 113 0.011
purine containing compound catabolic process GO:0072523 411 0.011
endocardial cushion development GO:0003197 3 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
ectodermal placode morphogenesis GO:0071697 1 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
definitive hemopoiesis GO:0060216 2 0.011
defense response to fungus GO:0050832 4 0.011
rna interference GO:0016246 4 0.011
negative regulation of organelle organization GO:0010639 126 0.011
positive regulation of chromosome organization GO:2001252 41 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
negative regulation of smooth muscle cell proliferation GO:0048662 14 0.011
protein targeting to nucleus GO:0044744 104 0.011
cellular response to lipid GO:0071396 127 0.011
regulation of body fluid levels GO:0050878 99 0.011
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.011
positive regulation of protein transport GO:0051222 135 0.011
ectodermal placode development GO:0071696 1 0.011
immune system development GO:0002520 195 0.011
neuron projection development GO:0031175 106 0.011
cell junction organization GO:0034330 79 0.010
histone h3 k4 demethylation GO:0034720 4 0.010
response to activity GO:0014823 0 0.010
purine nucleoside triphosphate metabolic process GO:0009144 412 0.010
stem cell development GO:0048864 69 0.010
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 3 0.010
regulation of lymphocyte activation GO:0051249 103 0.010
positive regulation of organelle organization GO:0010638 195 0.010
chromatin assembly or disassembly GO:0006333 78 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
steroid metabolic process GO:0008202 94 0.010
regulation of steroid metabolic process GO:0019218 32 0.010
regulation of chromosome organization GO:0033044 103 0.010
metal ion transport GO:0030001 272 0.010
histone lysine demethylation GO:0070076 14 0.010
regulation of cytokine production GO:0001817 232 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
lens development in camera type eye GO:0002088 2 0.010
regulation of microtubule based process GO:0032886 74 0.010
positive regulation of immune response GO:0050778 159 0.010

PELP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
musculoskeletal system disease DOID:17 223 0.013
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012