Homo sapiens

11 known processes

APBA3

amyloid beta (A4) precursor protein-binding, family A, member 3

(Aliases: MGC:15815,X11L2,mint3)

APBA3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of leukocyte degranulation GO:0043301 1 0.697
negative regulation of regulated secretory pathway GO:1903306 1 0.690
regulation of defense response GO:0031347 154 0.213
positive regulation of nucleotide catabolic process GO:0030813 185 0.202
rho protein signal transduction GO:0007266 26 0.166
inner ear morphogenesis GO:0042472 4 0.159
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.150
neutrophil activation involved in immune response GO:0002283 3 0.146
response to external biotic stimulus GO:0043207 261 0.143
response to other organism GO:0051707 261 0.140
response to lipopolysaccharide GO:0032496 70 0.140
regulation of exocytosis GO:0017157 46 0.121
regulation of response to external stimulus GO:0032101 222 0.111
regulation of cell cycle GO:0051726 393 0.105
vesicle mediated transport GO:0016192 371 0.104
regulation of gtp catabolic process GO:0033124 180 0.104
ribonucleoside triphosphate metabolic process GO:0009199 412 0.100
regulation of locomotion GO:0040012 329 0.099
neutrophil degranulation GO:0043312 3 0.098
nucleotide catabolic process GO:0009166 408 0.095
negative regulation of secretion GO:0051048 58 0.094
negative regulation of defense response GO:0031348 47 0.093
amine metabolic process GO:0009308 44 0.091
nucleoside triphosphate catabolic process GO:0009143 394 0.089
ras protein signal transduction GO:0007265 73 0.088
purine nucleoside triphosphate catabolic process GO:0009146 392 0.088
guanosine containing compound metabolic process GO:1901068 244 0.087
small gtpase mediated signal transduction GO:0007264 78 0.085
purine ribonucleotide catabolic process GO:0009154 404 0.082
purine ribonucleoside metabolic process GO:0046128 437 0.079
positive regulation of hydrolase activity GO:0051345 331 0.079
neuromuscular process GO:0050905 15 0.077
positive regulation of catabolic process GO:0009896 310 0.076
negative regulation of response to external stimulus GO:0032102 83 0.076
purine nucleoside triphosphate metabolic process GO:0009144 412 0.074
defense response GO:0006952 315 0.074
cellular response to cytokine stimulus GO:0071345 181 0.074
neutrophil mediated immunity GO:0002446 4 0.074
response to bacterium GO:0009617 144 0.073
purine containing compound catabolic process GO:0072523 411 0.072
response to biotic stimulus GO:0009607 276 0.069
glycosyl compound catabolic process GO:1901658 413 0.069
gtp catabolic process GO:0006184 237 0.069
regulation of nucleotide catabolic process GO:0030811 205 0.066
regulation of cellular amino acid metabolic process GO:0006521 6 0.064
purine ribonucleoside catabolic process GO:0046130 398 0.063
ribonucleoside catabolic process GO:0042454 406 0.063
regulation of immune response GO:0050776 201 0.062
cellular amino acid metabolic process GO:0006520 116 0.062
negative regulation of transport GO:0051051 176 0.062
regulation of cell migration GO:0030334 289 0.062
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.060
organophosphate catabolic process GO:0046434 430 0.059
membrane organization GO:0061024 292 0.059
Worm
nucleoside phosphate catabolic process GO:1901292 412 0.059
regulation of ras protein signal transduction GO:0046578 155 0.059
response to lipid GO:0033993 206 0.058
positive regulation of gtp catabolic process GO:0033126 166 0.058
nucleoside triphosphate metabolic process GO:0009141 422 0.057
cellular amine metabolic process GO:0044106 41 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.056
purine nucleoside catabolic process GO:0006152 398 0.056
cellular macromolecule catabolic process GO:0044265 380 0.054
signal transduction by phosphorylation GO:0023014 297 0.053
response to cytokine GO:0034097 232 0.052
regulation of secretion GO:0051046 194 0.052
locomotory behavior GO:0007626 1 0.051
immune response GO:0006955 307 0.050
ribonucleoside triphosphate catabolic process GO:0009203 391 0.049
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.049
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.049
protein ubiquitination GO:0016567 314 0.049
regulation of small gtpase mediated signal transduction GO:0051056 156 0.048
gtp metabolic process GO:0046039 239 0.047
response to molecule of bacterial origin GO:0002237 82 0.046
negative regulation of response to wounding GO:1903035 47 0.045
positive regulation of cellular catabolic process GO:0031331 284 0.045
positive regulation of gtpase activity GO:0043547 166 0.045
regulation of transferase activity GO:0051338 355 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
positive regulation of nucleotide metabolic process GO:0045981 230 0.044
negative regulation of protein metabolic process GO:0051248 391 0.044
regulation of cell cycle process GO:0010564 266 0.042
regulation of secretion by cell GO:1903530 177 0.042
system process GO:0003008 349 0.042
Worm
regulation of purine nucleotide catabolic process GO:0033121 205 0.042
response to oxygen containing compound GO:1901700 369 0.041
purine nucleotide catabolic process GO:0006195 405 0.040
regulation of anatomical structure morphogenesis GO:0022603 286 0.040
regulation of gtpase activity GO:0043087 180 0.040
exocytosis GO:0006887 71 0.039
positive regulation of cellular component organization GO:0051130 376 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.039
positive regulation of rho gtpase activity GO:0032321 56 0.038
regulation of response to wounding GO:1903034 101 0.038
secretion by cell GO:0032940 226 0.038
positive regulation of nucleoside metabolic process GO:0045979 186 0.038
regulation of rho protein signal transduction GO:0035023 79 0.037
regulation of inflammatory response GO:0050727 46 0.037
regulation of cell motility GO:2000145 299 0.037
negative regulation of leukocyte mediated immunity GO:0002704 14 0.037
regulation of purine nucleotide metabolic process GO:1900542 264 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.037
response to abiotic stimulus GO:0009628 336 0.036
negative regulation of secretion by cell GO:1903531 52 0.036
protein catabolic process GO:0030163 325 0.035
positive regulation of cellular amine metabolic process GO:0033240 7 0.035
negative regulation of locomotion GO:0040013 118 0.035
cellular protein catabolic process GO:0044257 261 0.035
negative regulation of cellular component movement GO:0051271 106 0.035
endosomal transport GO:0016197 129 0.035
female gamete generation GO:0007292 2 0.035
negative regulation of phosphorus metabolic process GO:0010563 267 0.035
negative regulation of immune effector process GO:0002698 38 0.034
regulation of kinase activity GO:0043549 314 0.034
positive regulation of transport GO:0051050 336 0.034
regulation of immune effector process GO:0002697 91 0.033
regulation of vesicle mediated transport GO:0060627 130 0.033
actin cytoskeleton organization GO:0030036 207 0.033
negative regulation of catalytic activity GO:0043086 335 0.033
leukocyte activation involved in immune response GO:0002366 30 0.033
negative regulation of phosphorylation GO:0042326 174 0.033
post embryonic development GO:0009791 2 0.032
Worm
segmentation GO:0035282 4 0.032
immune effector process GO:0002252 159 0.032
mapk cascade GO:0000165 288 0.032
peptidyl tyrosine phosphorylation GO:0018108 170 0.031
cellular response to endogenous stimulus GO:0071495 336 0.031
positive regulation of immune system process GO:0002684 283 0.031
modification dependent macromolecule catabolic process GO:0043632 212 0.031
response to wounding GO:0009611 168 0.030
regulation of nucleoside metabolic process GO:0009118 209 0.030
cellular ketone metabolic process GO:0042180 80 0.030
regulation of cellular component movement GO:0051270 334 0.030
regulation of rho gtpase activity GO:0032319 66 0.030
apoptotic signaling pathway GO:0097190 268 0.030
positive regulation of ras gtpase activity GO:0032320 117 0.029
nervous system development GO:0007399 293 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.029
endocytosis GO:0006897 159 0.028
modification dependent protein catabolic process GO:0019941 209 0.028
negative regulation of myeloid leukocyte mediated immunity GO:0002887 1 0.028
secretion GO:0046903 254 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
protein modification by small protein conjugation GO:0032446 342 0.027
regulation of proteolysis GO:0030162 293 0.027
establishment of protein localization to membrane GO:0090150 121 0.027
positive regulation of neural precursor cell proliferation GO:2000179 2 0.027
negative regulation of inflammatory response GO:0050728 22 0.027
lipid metabolic process GO:0006629 381 0.026
blastoderm segmentation GO:0007350 2 0.026
cytokine mediated signaling pathway GO:0019221 109 0.026
neuromuscular junction development GO:0007528 3 0.026
regulation of cellular ketone metabolic process GO:0010565 50 0.026
proteasomal protein catabolic process GO:0010498 176 0.026
chemical homeostasis GO:0048878 306 0.025
multicellular organismal aging GO:0010259 3 0.025
protein processing GO:0016485 226 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of cytokine production GO:0001817 232 0.025
intrinsic apoptotic signaling pathway GO:0097193 127 0.025
single organism membrane organization GO:0044802 268 0.024
Worm
innate immune response GO:0045087 178 0.024
positive regulation of developmental process GO:0051094 314 0.024
Worm
histone modification GO:0016570 251 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
neuromuscular process controlling balance GO:0050885 7 0.023
spermatid differentiation GO:0048515 4 0.023
cell development GO:0048468 328 0.023
actin filament based process GO:0030029 224 0.023
covalent chromatin modification GO:0016569 254 0.023
negative regulation of protein phosphorylation GO:0001933 140 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
compound eye development GO:0048749 1 0.023
Fly
cell activation GO:0001775 213 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
negative regulation of exocytosis GO:0045920 6 0.022
granulocyte activation GO:0036230 10 0.022
leukocyte activation GO:0045321 164 0.022
negative regulation of cell migration GO:0030336 102 0.022
biological adhesion GO:0022610 331 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
regulation of cell activation GO:0050865 125 0.022
ubiquitin dependent protein catabolic process GO:0006511 206 0.022
regulation of binding GO:0051098 111 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
brain development GO:0007420 97 0.021
associative learning GO:0008306 1 0.021
negative regulation of developmental process GO:0051093 247 0.021
myeloid leukocyte activation GO:0002274 34 0.021
central nervous system development GO:0007417 123 0.021
negative regulation of protein modification process GO:0031400 200 0.021
determination of adult lifespan GO:0008340 2 0.021
guanosine containing compound catabolic process GO:1901069 239 0.020
positive regulation of phagocytosis GO:0050766 15 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
protein targeting GO:0006605 187 0.020
cell activation involved in immune response GO:0002263 30 0.020
intracellular protein transport GO:0006886 270 0.020
regulation of endocytosis GO:0030100 72 0.020
epithelium development GO:0060429 227 0.020
immune response activating signal transduction GO:0002757 90 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
plasma membrane organization GO:0007009 115 0.019
Worm
positive regulation of protein phosphorylation GO:0001934 313 0.019
defense response to other organism GO:0098542 129 0.019
positive regulation of cell death GO:0010942 263 0.019
organ morphogenesis GO:0009887 147 0.019
negative regulation of cell cycle GO:0045786 193 0.019
regulation of protein catabolic process GO:0042176 155 0.018
negative regulation of cell motility GO:2000146 104 0.018
regulation of protein kinase activity GO:0045859 289 0.018
positive regulation of cytokine production GO:0001819 167 0.018
positive regulation of cell differentiation GO:0045597 211 0.018
protein localization to organelle GO:0033365 280 0.018
response to virus GO:0009615 126 0.018
single organism cellular localization GO:1902580 332 0.018
Worm
oocyte development GO:0048599 1 0.018
spermatid development GO:0007286 4 0.018
microtubule cytoskeleton organization GO:0000226 176 0.018
regulation of cytokine mediated signaling pathway GO:0001959 41 0.018
activation of immune response GO:0002253 114 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
negative regulation of protein processing GO:0010955 142 0.018
inflammatory response GO:0006954 79 0.017
response to nitrogen compound GO:1901698 184 0.017
rna processing GO:0006396 255 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
small molecule biosynthetic process GO:0044283 157 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
maintenance of location GO:0051235 112 0.017
regulation of erk1 and erk2 cascade GO:0070372 99 0.017
somitogenesis GO:0001756 2 0.016
regulation of protein localization GO:0032880 296 0.016
peptidyl tyrosine modification GO:0018212 170 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
negative regulation of leukocyte activation GO:0002695 26 0.016
cellular cation homeostasis GO:0030003 163 0.016
regulation of map kinase activity GO:0043405 108 0.016
cation transport GO:0006812 331 0.016
regulation of cell division GO:0051302 116 0.016
protein maturation GO:0051604 233 0.016
positive regulation of endocytosis GO:0045807 42 0.016
blood vessel morphogenesis GO:0048514 162 0.016
response to oxidative stress GO:0006979 121 0.015
regulation of peptidase activity GO:0052547 180 0.015
positive regulation of transferase activity GO:0051347 227 0.015
ameboidal type cell migration GO:0001667 135 0.015
blood vessel development GO:0001568 172 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
regulation of intracellular transport GO:0032386 195 0.015
ion homeostasis GO:0050801 230 0.015
neutrophil activation GO:0042119 9 0.015
jak stat cascade GO:0007259 46 0.015
regulation of growth GO:0040008 165 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
negative regulation of cytokine production GO:0001818 82 0.015
protein localization to membrane GO:0072657 160 0.015
Worm
regulation of neural precursor cell proliferation GO:2000177 4 0.015
regulation of protein maturation GO:1903317 150 0.014
regulation of nervous system development GO:0051960 88 0.014
regulation of regulated secretory pathway GO:1903305 10 0.014
response to growth factor GO:0070848 205 0.014
memory GO:0007613 3 0.014
negative regulation of protein kinase activity GO:0006469 98 0.014
cellular homeostasis GO:0019725 196 0.014
neurotransmitter secretion GO:0007269 4 0.014
embryonic morphogenesis GO:0048598 85 0.014
mitotic cell cycle GO:0000278 326 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
cytoplasmic transport GO:0016482 379 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
response to fungus GO:0009620 4 0.014
peptidyl serine phosphorylation GO:0018105 101 0.014
immune system development GO:0002520 195 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
sex determination GO:0007530 3 0.014
head development GO:0060322 108 0.014
regeneration GO:0031099 4 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
oogenesis GO:0048477 2 0.014
epithelium migration GO:0090132 119 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
chromatin modification GO:0016568 298 0.014
chromatin organization GO:0006325 351 0.014
anterior posterior axis specification GO:0009948 2 0.014
single organism cell adhesion GO:0098602 179 0.014
cytokine production GO:0001816 247 0.014
mitotic cell cycle process GO:1903047 286 0.014
regulation of proteasomal protein catabolic process GO:0061136 87 0.014
positive regulation of cell cycle process GO:0090068 106 0.013
rhythmic behavior GO:0007622 2 0.013
tripartite regional subdivision GO:0007351 2 0.013
cell cycle arrest GO:0007050 71 0.013
positive regulation of secretion by cell GO:1903532 108 0.013
sterol transport GO:0015918 39 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
negative regulation of growth GO:0045926 97 0.013
response to organonitrogen compound GO:0010243 156 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
cellular response to oxidative stress GO:0034599 85 0.013
regulated secretory pathway GO:0045055 20 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
negative regulation of cell activation GO:0050866 33 0.013
regulation of protein processing GO:0070613 150 0.013
dephosphorylation GO:0016311 209 0.013
neuroblast proliferation GO:0007405 4 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
positive regulation of locomotion GO:0040017 186 0.013
positive regulation of cell division GO:0051781 59 0.013
immune response regulating signaling pathway GO:0002764 97 0.013
regulation of neutrophil activation GO:1902563 1 0.013
positive regulation of innate immune response GO:0045089 79 0.013
cellular response to tumor necrosis factor GO:0071356 63 0.013
visual learning GO:0008542 1 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
regulation of protein binding GO:0043393 66 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
sulfur compound biosynthetic process GO:0044272 38 0.012
cellular ion homeostasis GO:0006873 168 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
positive regulation of kinase activity GO:0033674 204 0.012
positive regulation of rab gtpase activity GO:0032851 39 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
cell projection organization GO:0030030 252 0.012
positive regulation of immune response GO:0050778 159 0.012
convergent extension GO:0060026 1 0.012
dna repair GO:0006281 198 0.012
regulation of multi organism process GO:0043900 157 0.012
lipid transport GO:0006869 90 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
somatic stem cell division GO:0048103 1 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.012
response to tumor necrosis factor GO:0034612 76 0.012
type i interferon signaling pathway GO:0060337 11 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
phagocytosis GO:0006909 42 0.012
alcohol metabolic process GO:0006066 114 0.012
regulation of innate immune response GO:0045088 97 0.012
positive regulation of intracellular transport GO:0032388 104 0.012
regulation of cell differentiation GO:0045595 393 0.012
positive regulation of defense response GO:0031349 87 0.012
embryonic organ morphogenesis GO:0048562 24 0.012
cation homeostasis GO:0055080 189 0.012
oocyte differentiation GO:0009994 2 0.012
positive regulation of t cell receptor signaling pathway GO:0050862 2 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
cell junction organization GO:0034330 79 0.012
protein homooligomerization GO:0051260 100 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
circadian behavior GO:0048512 2 0.011
response to radiation GO:0009314 151 0.011
positive regulation of cell cycle GO:0045787 140 0.011
regulation of response to cytokine stimulus GO:0060759 46 0.011
epithelial cell migration GO:0010631 119 0.011
positive regulation of proteolysis GO:0045862 142 0.011
hindbrain development GO:0030902 3 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
inorganic anion transmembrane transport GO:0098661 47 0.011
angiogenesis GO:0001525 147 0.011
long term memory GO:0007616 2 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.011
cell growth GO:0016049 160 0.011
chemotaxis GO:0006935 157 0.011
hemopoiesis GO:0030097 180 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
rab protein signal transduction GO:0032482 4 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
cell morphogenesis GO:0000902 296 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
regulation of protein complex assembly GO:0043254 147 0.011
steroid metabolic process GO:0008202 94 0.011
regulation of receptor activity GO:0010469 47 0.011
growth GO:0040007 202 0.010
asymmetric stem cell division GO:0098722 1 0.010
sensory organ morphogenesis GO:0090596 21 0.010
lipid localization GO:0010876 106 0.010
establishment of tissue polarity GO:0007164 3 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.010
negative regulation of proteolysis GO:0045861 132 0.010
cellular component morphogenesis GO:0032989 314 0.010
regulation of protein transport GO:0051223 213 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.010
cellular chemical homeostasis GO:0055082 180 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
defense response to virus GO:0051607 71 0.010
lymphocyte activation GO:0046649 133 0.010
organic anion transport GO:0015711 103 0.010
visual behavior GO:0007632 2 0.010

APBA3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.114
disease of cellular proliferation DOID:14566 174 0.114
organ system cancer DOID:0050686 164 0.114
central nervous system disease DOID:331 186 0.031
nervous system disease DOID:863 431 0.031
disease of metabolism DOID:0014667 295 0.018
musculoskeletal system disease DOID:17 223 0.016
immune system cancer DOID:0060083 36 0.014
hematologic cancer DOID:2531 36 0.014
sensory system disease DOID:0050155 203 0.014