Homo sapiens

30 known processes

SKA2

spindle and kinetochore associated complex subunit 2

(Aliases: MGC110975,FLJ12758,FAM33A)

SKA2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.867
microtubule polymerization or depolymerization GO:0031109 37 0.582
microtubule cytoskeleton organization GO:0000226 176 0.455
regulation of microtubule cytoskeleton organization GO:0070507 61 0.454
regulation of microtubule based process GO:0032886 74 0.454
mitotic nuclear division GO:0007067 119 0.258
regulation of cytoskeleton organization GO:0051493 177 0.245
organelle fission GO:0048285 149 0.207
positive regulation of cell cycle GO:0045787 140 0.186
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.184
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.181
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.179
microtubule based process GO:0007017 210 0.177
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.169
protein processing GO:0016485 226 0.167
somatic stem cell division GO:0048103 1 0.143
regulation of mitotic sister chromatid separation GO:0010965 27 0.126
negative regulation of protein metabolic process GO:0051248 391 0.119
modification dependent protein catabolic process GO:0019941 209 0.118
regulation of chromosome organization GO:0033044 103 0.110
chromosome separation GO:0051304 23 0.094
regulation of mitotic sister chromatid segregation GO:0033047 27 0.093
mitotic cell cycle GO:0000278 326 0.092
mitotic sister chromatid separation GO:0051306 18 0.092
mitotic cytokinesis GO:0000281 19 0.087
wnt signaling pathway GO:0016055 156 0.085
nuclear division GO:0000280 128 0.085
sister chromatid segregation GO:0000819 54 0.078
regulation of mitosis GO:0007088 63 0.077
positive regulation of cell cycle process GO:0090068 106 0.076
protein dephosphorylation GO:0006470 81 0.075
single organism cellular localization GO:1902580 332 0.075
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.071
negative regulation of protein maturation GO:1903318 142 0.071
neuroblast proliferation GO:0007405 4 0.070
negative regulation of catabolic process GO:0009895 104 0.069
negative regulation of cellular catabolic process GO:0031330 83 0.068
chromatin organization GO:0006325 351 0.062
regulation of chromosome segregation GO:0051983 44 0.058
cell type specific apoptotic process GO:0097285 125 0.056
intracellular protein transport GO:0006886 270 0.053
regulation of cell cycle process GO:0010564 266 0.052
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.051
oogenesis GO:0048477 2 0.051
regulation of cellular protein catabolic process GO:1903362 96 0.049
negative regulation of sister chromatid segregation GO:0033046 17 0.049
cytokinesis GO:0000910 96 0.049
regulation of dephosphorylation GO:0035303 96 0.046
nervous system development GO:0007399 293 0.045
negative regulation of protein catabolic process GO:0042177 59 0.044
chromatin modification GO:0016568 298 0.043
mitotic sister chromatid segregation GO:0000070 53 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
spermatid development GO:0007286 4 0.040
negative regulation of proteolysis GO:0045861 132 0.040
mitotic spindle assembly checkpoint GO:0007094 14 0.039
neuronal stem cell division GO:0036445 1 0.038
regulation of phosphatase activity GO:0010921 81 0.038
covalent chromatin modification GO:0016569 254 0.038
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.038
mitotic spindle checkpoint GO:0071174 18 0.038
regulation of sister chromatid segregation GO:0033045 27 0.037
mitochondrial fission GO:0000266 14 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.035
chromosome segregation GO:0007059 114 0.035
ubiquitin dependent protein catabolic process GO:0006511 206 0.034
stem cell division GO:0017145 2 0.034
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.034
multicellular organismal aging GO:0010259 3 0.034
endomembrane system organization GO:0010256 196 0.034
regulation of protein catabolic process GO:0042176 155 0.034
positive regulation of programmed cell death GO:0043068 249 0.034
cellular macromolecular complex assembly GO:0034622 324 0.034
mitotic cell cycle process GO:1903047 286 0.034
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
cytoskeleton dependent cytokinesis GO:0061640 22 0.033
cell development GO:0048468 328 0.033
protein catabolic process GO:0030163 325 0.032
cell cycle phase transition GO:0044770 173 0.032
positive regulation of cell cycle g2 m phase transition GO:1902751 8 0.032
regulation of nuclear division GO:0051783 65 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.032
metaphase anaphase transition of cell cycle GO:0044784 21 0.030
negative regulation of mitosis GO:0045839 24 0.030
i kappab kinase nf kappab signaling GO:0007249 166 0.030
post embryonic development GO:0009791 2 0.029
ameboidal type cell migration GO:0001667 135 0.028
embryo development GO:0009790 123 0.028
protein localization to nucleus GO:0034504 136 0.028
cell division GO:0051301 168 0.028
negative regulation of organelle organization GO:0010639 126 0.027
centrosome organization GO:0051297 58 0.027
negative regulation of chromosome segregation GO:0051985 18 0.027
modification dependent macromolecule catabolic process GO:0043632 212 0.027
regulation of cell differentiation GO:0045595 393 0.026
dephosphorylation GO:0016311 209 0.026
cellular ketone metabolic process GO:0042180 80 0.026
negative regulation of cell division GO:0051782 31 0.026
regulation of cell division GO:0051302 116 0.026
organelle assembly GO:0070925 176 0.026
regulation of protein processing GO:0070613 150 0.025
positive regulation of protein localization to nucleus GO:1900182 48 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.024
reproductive process GO:0022414 106 0.024
cellular amino acid metabolic process GO:0006520 116 0.024
cellular amine metabolic process GO:0044106 41 0.023
asymmetric neuroblast division GO:0055059 1 0.023
female gamete generation GO:0007292 2 0.023
histone modification GO:0016570 251 0.023
rho protein signal transduction GO:0007266 26 0.023
negative regulation of chromosome organization GO:2001251 48 0.023
negative regulation of protein processing GO:0010955 142 0.022
regulation of protein localization to nucleus GO:1900180 85 0.022
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.022
regulation of neuron apoptotic process GO:0043523 35 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
regulation of cell development GO:0060284 161 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
response to light stimulus GO:0009416 87 0.021
regulation of immune response GO:0050776 201 0.021
innate immune response GO:0045087 178 0.021
neuron death GO:0070997 65 0.021
behavior GO:0007610 112 0.021
response to abiotic stimulus GO:0009628 336 0.020
protein maturation GO:0051604 233 0.020
proteasomal protein catabolic process GO:0010498 176 0.020
neuron apoptotic process GO:0051402 39 0.020
regulation of cell cycle phase transition GO:1901987 126 0.020
negative regulation of cytokinesis GO:0032466 3 0.019
sensory organ development GO:0007423 52 0.019
regulation of cellular component movement GO:0051270 334 0.019
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.019
regulation of proteasomal protein catabolic process GO:0061136 87 0.019
microtubule organizing center organization GO:0031023 62 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.018
regulation of neuron death GO:1901214 56 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
regulation of proteolysis GO:0030162 293 0.018
amine metabolic process GO:0009308 44 0.018
regulation of protein localization GO:0032880 296 0.017
negative regulation of cell cycle process GO:0010948 121 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.017
cdc42 protein signal transduction GO:0032488 4 0.017
establishment or maintenance of cell polarity GO:0007163 31 0.017
response to growth factor GO:0070848 205 0.017
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.017
cellular protein catabolic process GO:0044257 261 0.017
g2 m transition of mitotic cell cycle GO:0000086 41 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
meiotic chromosome segregation GO:0045132 4 0.016
developmental process involved in reproduction GO:0003006 66 0.016
regulation of cytokinesis GO:0032465 45 0.016
defense response GO:0006952 315 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
positive regulation of cell division GO:0051781 59 0.016
cell chemotaxis GO:0060326 112 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
protein targeting GO:0006605 187 0.016
regulation of cell cycle g2 m phase transition GO:1902749 22 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
cell projection assembly GO:0030031 126 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
regulation of locomotion GO:0040012 329 0.015
positive regulation of mitotic cell cycle GO:0045931 60 0.015
negative regulation of developmental process GO:0051093 247 0.015
biological adhesion GO:0022610 331 0.014
spindle organization GO:0007051 53 0.014
secretion GO:0046903 254 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
response to biotic stimulus GO:0009607 276 0.014
asymmetric stem cell division GO:0098722 1 0.014
positive regulation of organelle organization GO:0010638 195 0.013
regulation of meiosis GO:0040020 3 0.013
negative regulation of cell death GO:0060548 345 0.013
maintenance of location GO:0051235 112 0.013
spermatid differentiation GO:0048515 4 0.012
cell projection organization GO:0030030 252 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
methylation GO:0032259 106 0.012
blood vessel morphogenesis GO:0048514 162 0.012
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
regulation of cell migration GO:0030334 289 0.012
protein ubiquitination GO:0016567 314 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
dna repair GO:0006281 198 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
cell cycle g2 m phase transition GO:0044839 43 0.012
secretion by cell GO:0032940 226 0.012
cell cycle checkpoint GO:0000075 117 0.012
negative regulation of cell proliferation GO:0008285 228 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
rna processing GO:0006396 255 0.011
reproduction GO:0000003 63 0.011
protein autoubiquitination GO:0051865 37 0.011
golgi organization GO:0007030 38 0.011
response to oxidative stress GO:0006979 121 0.011
regulation of rho protein signal transduction GO:0035023 79 0.011
regulation of chromatin organization GO:1902275 56 0.011
peptidyl serine modification GO:0018209 106 0.011
single organism membrane organization GO:0044802 268 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
autophagy GO:0006914 88 0.011
viral life cycle GO:0019058 132 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
regulation of cell motility GO:2000145 299 0.010
protein stabilization GO:0050821 64 0.010
response to other organism GO:0051707 261 0.010
gtp catabolic process GO:0006184 237 0.010
regulation of neurogenesis GO:0050767 82 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
mitotic cell cycle checkpoint GO:0007093 68 0.010
cell adhesion GO:0007155 325 0.010

SKA2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.039
neurodegenerative disease DOID:1289 102 0.039
nervous system disease DOID:863 431 0.039
immune system disease DOID:2914 155 0.025
hematopoietic system disease DOID:74 100 0.019
anemia DOID:2355 55 0.011