Homo sapiens

0 known processes

PLEKHO2

pleckstrin homology domain containing, family O member 2

(Aliases: PP1628,FLJ38884,PLEKHQ1,pp9099,DKFZp761K2312)

PLEKHO2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside catabolic process GO:0009164 408 0.162
purine ribonucleoside catabolic process GO:0046130 398 0.143
purine containing compound catabolic process GO:0072523 411 0.130
organophosphate catabolic process GO:0046434 430 0.111
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.108
nucleotide catabolic process GO:0009166 408 0.106
purine nucleoside triphosphate metabolic process GO:0009144 412 0.103
purine nucleoside catabolic process GO:0006152 398 0.101
purine nucleotide catabolic process GO:0006195 405 0.100
amine metabolic process GO:0009308 44 0.098
gtp catabolic process GO:0006184 237 0.092
regulation of cellular amino acid metabolic process GO:0006521 6 0.089
nucleoside phosphate catabolic process GO:1901292 412 0.088
regulation of cellular ketone metabolic process GO:0010565 50 0.088
guanosine containing compound metabolic process GO:1901068 244 0.084
cellular amine metabolic process GO:0044106 41 0.083
ribonucleoside triphosphate catabolic process GO:0009203 391 0.082
purine ribonucleoside metabolic process GO:0046128 437 0.082
purine nucleoside triphosphate catabolic process GO:0009146 392 0.081
nucleoside triphosphate catabolic process GO:0009143 394 0.077
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.076
regulation of gtp catabolic process GO:0033124 180 0.075
guanosine containing compound catabolic process GO:1901069 239 0.072
positive regulation of hydrolase activity GO:0051345 331 0.071
gtp metabolic process GO:0046039 239 0.071
ribonucleoside catabolic process GO:0042454 406 0.071
ribonucleotide catabolic process GO:0009261 405 0.071
small gtpase mediated signal transduction GO:0007264 78 0.070
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.069
immune response GO:0006955 307 0.069
regulation of locomotion GO:0040012 329 0.068
purine ribonucleotide catabolic process GO:0009154 404 0.066
positive regulation of gtp catabolic process GO:0033126 166 0.065
biological adhesion GO:0022610 331 0.063
positive regulation of nucleotide metabolic process GO:0045981 230 0.061
single organism cellular localization GO:1902580 332 0.059
nucleoside triphosphate metabolic process GO:0009141 422 0.059
regulation of nucleotide catabolic process GO:0030811 205 0.058
positive regulation of nucleoside metabolic process GO:0045979 186 0.058
glycosyl compound catabolic process GO:1901658 413 0.056
actin filament based process GO:0030029 224 0.056
regulation of cell migration GO:0030334 289 0.056
cellular ketone metabolic process GO:0042180 80 0.054
cell activation GO:0001775 213 0.053
rho protein signal transduction GO:0007266 26 0.052
positive regulation of cellular catabolic process GO:0031331 284 0.052
actin cytoskeleton organization GO:0030036 207 0.052
regulation of cell motility GO:2000145 299 0.052
regulation of cellular component movement GO:0051270 334 0.052
positive regulation of gtpase activity GO:0043547 166 0.051
regulation of purine nucleotide catabolic process GO:0033121 205 0.050
hematopoietic or lymphoid organ development GO:0048534 186 0.049
regulation of cell differentiation GO:0045595 393 0.048
regulation of response to external stimulus GO:0032101 222 0.048
ras protein signal transduction GO:0007265 73 0.048
vesicle mediated transport GO:0016192 371 0.047
regulation of purine nucleotide metabolic process GO:1900542 264 0.046
regulation of protein localization GO:0032880 296 0.045
regulation of cytokine production GO:0001817 232 0.045
positive regulation of cellular amine metabolic process GO:0033240 7 0.044
regulation of nucleoside metabolic process GO:0009118 209 0.044
activation of immune response GO:0002253 114 0.043
positive regulation of phosphorylation GO:0042327 394 0.043
regulation of establishment of protein localization GO:0070201 242 0.043
negative regulation of phosphorus metabolic process GO:0010563 267 0.043
cell projection organization GO:0030030 252 0.042
ribonucleoside triphosphate metabolic process GO:0009199 412 0.042
cytokine production GO:0001816 247 0.042
response to external biotic stimulus GO:0043207 261 0.041
positive regulation of nucleotide catabolic process GO:0030813 185 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.040
regulation of immune response GO:0050776 201 0.040
positive regulation of immune system process GO:0002684 283 0.040
post embryonic development GO:0009791 2 0.039
regulation of nucleotide metabolic process GO:0006140 269 0.039
actin filament organization GO:0007015 128 0.039
positive regulation of ras gtpase activity GO:0032320 117 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.038
single organismal cell cell adhesion GO:0016337 148 0.038
regulation of protein transport GO:0051223 213 0.037
leukocyte activation GO:0045321 164 0.037
hemopoiesis GO:0030097 180 0.037
intracellular protein transport GO:0006886 270 0.037
cellular amino acid metabolic process GO:0006520 116 0.037
cellular component morphogenesis GO:0032989 314 0.036
regulation of defense response GO:0031347 154 0.036
determination of adult lifespan GO:0008340 2 0.036
single organism membrane organization GO:0044802 268 0.035
negative regulation of cell proliferation GO:0008285 228 0.035
positive regulation of protein phosphorylation GO:0001934 313 0.035
positive regulation of cell motility GO:2000147 177 0.035
regulation of actin cytoskeleton organization GO:0032956 116 0.034
regulation of cellular component biogenesis GO:0044087 281 0.034
positive regulation of catabolic process GO:0009896 310 0.034
regulation of cytoskeleton organization GO:0051493 177 0.034
regulation of mapk cascade GO:0043408 262 0.034
defense response GO:0006952 315 0.034
positive regulation of cellular component organization GO:0051130 376 0.033
immune response activating signal transduction GO:0002757 90 0.033
regulation of leukocyte activation GO:0002694 115 0.033
negative regulation of phosphate metabolic process GO:0045936 267 0.033
multicellular organismal aging GO:0010259 3 0.033
protein localization to membrane GO:0072657 160 0.033
oogenesis GO:0048477 2 0.032
regulation of gtpase activity GO:0043087 180 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
enzyme linked receptor protein signaling pathway GO:0007167 303 0.032
response to biotic stimulus GO:0009607 276 0.031
immune system development GO:0002520 195 0.031
negative regulation of multicellular organismal process GO:0051241 317 0.031
membrane organization GO:0061024 292 0.031
regulation of cell activation GO:0050865 125 0.031
regulation of actin filament based process GO:0032970 141 0.031
regulation of protein kinase activity GO:0045859 289 0.030
positive regulation of cellular component movement GO:0051272 181 0.030
signal transduction by phosphorylation GO:0023014 297 0.030
cell projection assembly GO:0030031 126 0.030
female gamete generation GO:0007292 2 0.029
segmentation GO:0035282 4 0.029
leukocyte differentiation GO:0002521 98 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
negative regulation of immune system process GO:0002683 136 0.028
response to other organism GO:0051707 261 0.028
immune response regulating signaling pathway GO:0002764 97 0.028
regulation of anatomical structure morphogenesis GO:0022603 286 0.028
cytoplasmic transport GO:0016482 379 0.028
positive regulation of rho gtpase activity GO:0032321 56 0.028
positive regulation of cytoskeleton organization GO:0051495 83 0.027
lipid metabolic process GO:0006629 381 0.027
cation transport GO:0006812 331 0.027
transmembrane transport GO:0055085 399 0.027
positive regulation of transport GO:0051050 336 0.027
cell adhesion GO:0007155 325 0.027
system process GO:0003008 349 0.027
positive regulation of immune response GO:0050778 159 0.027
innate immune response GO:0045087 178 0.026
regulation of ras gtpase activity GO:0032318 128 0.026
positive regulation of organelle organization GO:0010638 195 0.026
secretion by cell GO:0032940 226 0.026
regulation of rho gtpase activity GO:0032319 66 0.026
single organism cell adhesion GO:0098602 179 0.026
regulation of vesicle mediated transport GO:0060627 130 0.026
protein localization to plasma membrane GO:0072659 93 0.025
dephosphorylation GO:0016311 209 0.025
regulation of response to wounding GO:1903034 101 0.025
endomembrane system organization GO:0010256 196 0.025
regulation of leukocyte proliferation GO:0070663 67 0.025
cell morphogenesis GO:0000902 296 0.024
regulation of cell adhesion GO:0030155 166 0.024
regulation of intracellular transport GO:0032386 195 0.024
response to oxygen containing compound GO:1901700 369 0.024
positive regulation of cellular component biogenesis GO:0044089 158 0.024
single organism carbohydrate metabolic process GO:0044723 193 0.024
negative regulation of cellular amine metabolic process GO:0033239 3 0.023
regulation of kinase activity GO:0043549 314 0.023
regulation of transferase activity GO:0051338 355 0.023
response to bacterium GO:0009617 144 0.023
anterior posterior axis specification GO:0009948 2 0.022
defense response to other organism GO:0098542 129 0.022
purine nucleoside monophosphate catabolic process GO:0009128 158 0.022
secretion GO:0046903 254 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
regulation of small gtpase mediated signal transduction GO:0051056 156 0.022
positive regulation of transferase activity GO:0051347 227 0.022
response to nitrogen compound GO:1901698 184 0.022
lymphocyte activation GO:0046649 133 0.022
negative regulation of protein modification process GO:0031400 200 0.021
cellular lipid metabolic process GO:0044255 303 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
purine nucleoside monophosphate metabolic process GO:0009126 186 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
protein modification by small protein conjugation GO:0032446 342 0.021
positive regulation of cytokine production GO:0001819 167 0.021
regulation of rho protein signal transduction GO:0035023 79 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
cell development GO:0048468 328 0.020
protein catabolic process GO:0030163 325 0.020
regulation of ras protein signal transduction GO:0046578 155 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
chemical homeostasis GO:0048878 306 0.020
microtubule based process GO:0007017 210 0.020
ribonucleoside monophosphate catabolic process GO:0009158 158 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
immune effector process GO:0002252 159 0.020
leukocyte proliferation GO:0070661 74 0.020
exocytosis GO:0006887 71 0.020
positive regulation of locomotion GO:0040017 186 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
positive regulation of cell migration GO:0030335 172 0.019
negative regulation of cell death GO:0060548 345 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
maintenance of location GO:0051235 112 0.019
regulation of protein complex assembly GO:0043254 147 0.019
leukocyte migration GO:0050900 107 0.019
mitotic cell cycle GO:0000278 326 0.018
response to abiotic stimulus GO:0009628 336 0.018
positive regulation of kinase activity GO:0033674 204 0.018
positive regulation of developmental process GO:0051094 314 0.018
protein targeting GO:0006605 187 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
plasma membrane organization GO:0007009 115 0.018
endocytosis GO:0006897 159 0.018
platelet activation GO:0030168 44 0.018
peptidyl tyrosine modification GO:0018212 170 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
cellular protein catabolic process GO:0044257 261 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
peptidyl tyrosine phosphorylation GO:0018108 170 0.017
cell chemotaxis GO:0060326 112 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
small molecule biosynthetic process GO:0044283 157 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
regulation of body fluid levels GO:0050878 99 0.017
response to organonitrogen compound GO:0010243 156 0.017
taxis GO:0042330 157 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
regulation of cellular response to stress GO:0080135 244 0.016
actin filament bundle assembly GO:0051017 54 0.016
cell substrate adhesion GO:0031589 132 0.016
blastoderm segmentation GO:0007350 2 0.016
response to hormone GO:0009725 175 0.016
atp catabolic process GO:0006200 157 0.016
positive regulation of cell death GO:0010942 263 0.016
nuclear transport GO:0051169 179 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
negative regulation of phagocytosis GO:0050765 4 0.016
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.016
sex determination GO:0007530 3 0.016
mapk cascade GO:0000165 288 0.016
cell part morphogenesis GO:0032990 137 0.015
vasculature development GO:0001944 181 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
actin filament bundle organization GO:0061572 54 0.015
regulation of cell cycle GO:0051726 393 0.015
lipid localization GO:0010876 106 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
regulation of leukocyte migration GO:0002685 63 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
neurological system process GO:0050877 163 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
positive regulation of cell adhesion GO:0045785 84 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
negative regulation of platelet aggregation GO:0090331 3 0.015
regulation of dephosphorylation GO:0035303 96 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
inflammatory response GO:0006954 79 0.015
amino sugar catabolic process GO:0046348 3 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
regulation of innate immune response GO:0045088 97 0.015
mononuclear cell proliferation GO:0032943 71 0.015
metal ion transport GO:0030001 272 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.015
lipid biosynthetic process GO:0008610 177 0.014
defense response to virus GO:0051607 71 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
regulation of phosphatase activity GO:0010921 81 0.014
positive regulation of defense response GO:0031349 87 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
regeneration GO:0031099 4 0.014
cation homeostasis GO:0055080 189 0.014
atp metabolic process GO:0046034 176 0.014
circulatory system development GO:0072359 262 0.014
cellular chemical homeostasis GO:0055082 180 0.014
protein maturation GO:0051604 233 0.014
cell matrix adhesion GO:0007160 85 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
response to wounding GO:0009611 168 0.014
cdc42 protein signal transduction GO:0032488 4 0.014
mitotic cell cycle process GO:1903047 286 0.014
cellular response to external stimulus GO:0071496 111 0.014
spermatid development GO:0007286 4 0.014
regulation of secretion by cell GO:1903530 177 0.014
myeloid leukocyte migration GO:0097529 62 0.014
protein ubiquitination GO:0016567 314 0.014
spermatid differentiation GO:0048515 4 0.013
nitrogen compound transport GO:0071705 191 0.013
regulation of cell projection organization GO:0031344 107 0.013
cellular homeostasis GO:0019725 196 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
ion transmembrane transport GO:0034220 338 0.013
cell cell signaling GO:0007267 155 0.013
tissue migration GO:0090130 119 0.013
negative regulation of cell cycle GO:0045786 193 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
neuromuscular junction development GO:0007528 3 0.013
endosomal transport GO:0016197 129 0.013
phospholipid metabolic process GO:0006644 99 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
carbohydrate metabolic process GO:0005975 207 0.013
regulation of secretion GO:0051046 194 0.013
negative regulation of organelle organization GO:0010639 126 0.013
monovalent inorganic cation transport GO:0015672 128 0.013
organic hydroxy compound transport GO:0015850 63 0.013
epithelial cell proliferation GO:0050673 128 0.013
detection of chemical stimulus GO:0009593 55 0.013
oocyte development GO:0048599 1 0.013
tumor necrosis factor production GO:0032640 43 0.013
neurotransmitter secretion GO:0007269 4 0.013
protein targeting to nucleus GO:0044744 104 0.013
apoptotic signaling pathway GO:0097190 268 0.013
positive regulation of protein transport GO:0051222 135 0.012
glycerolipid metabolic process GO:0046486 107 0.012
leukocyte mediated immunity GO:0002443 59 0.012
regulation of wound healing GO:0061041 56 0.012
regulation of angiogenesis GO:0045765 92 0.012
hemostasis GO:0007599 76 0.012
regulation of erk1 and erk2 cascade GO:0070372 99 0.012
regulation of tumor necrosis factor production GO:0032680 43 0.012
single organism nuclear import GO:1902593 104 0.012
protein processing GO:0016485 226 0.012
chemotaxis GO:0006935 157 0.012
glycerophospholipid metabolic process GO:0006650 84 0.012
regulation of blood coagulation GO:0030193 42 0.012
lymphocyte proliferation GO:0046651 70 0.012
epithelial cell migration GO:0010631 119 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
nervous system development GO:0007399 293 0.012
positive regulation of secretion GO:0051047 116 0.012
peripheral nervous system development GO:0007422 2 0.012
negative regulation of cell motility GO:2000146 104 0.012
innate immune response activating signal transduction GO:0002758 48 0.012
blood vessel morphogenesis GO:0048514 162 0.012
cellular protein complex assembly GO:0043623 188 0.012
wnt signaling pathway GO:0016055 156 0.012
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.012
alcohol metabolic process GO:0006066 114 0.012
regulation of proteolysis GO:0030162 293 0.012
negative regulation of transferase activity GO:0051348 124 0.012
oocyte differentiation GO:0009994 2 0.012
nerve development GO:0021675 4 0.012
protein localization to nucleus GO:0034504 136 0.012
organelle localization GO:0051640 84 0.012
chromosome segregation GO:0007059 114 0.012
tripartite regional subdivision GO:0007351 2 0.012
locomotory behavior GO:0007626 1 0.012
regulation of mitotic cell cycle GO:0007346 189 0.011
protein oligomerization GO:0051259 173 0.011
lymphocyte mediated immunity GO:0002449 48 0.011
response to growth factor GO:0070848 205 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
regulation of phagocytosis engulfment GO:0060099 2 0.011
regulation of mast cell degranulation GO:0043304 3 0.011
somatic stem cell maintenance GO:0035019 4 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
regulation of cell projection assembly GO:0060491 47 0.011
actin polymerization or depolymerization GO:0008154 56 0.011
hindbrain development GO:0030902 3 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
sensory perception of smell GO:0007608 2 0.011
negative regulation of developmental process GO:0051093 247 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
purine nucleotide biosynthetic process GO:0006164 84 0.011
mast cell activation involved in immune response GO:0002279 4 0.011
memory GO:0007613 3 0.011
regulation of protein catabolic process GO:0042176 155 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
cation transmembrane transport GO:0098655 238 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
negative regulation of cytokine production GO:0001818 82 0.011
regulation of cell cycle process GO:0010564 266 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
multi organism cellular process GO:0044764 156 0.011
sensory perception GO:0007600 103 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
cell cycle phase transition GO:0044770 173 0.011
negative regulation of blood pressure GO:0045776 3 0.011
positive regulation of rac gtpase activity GO:0032855 31 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.011
compound eye development GO:0048749 1 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
organelle assembly GO:0070925 176 0.011
rna interference GO:0016246 4 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.011
negative regulation of alpha beta t cell activation GO:0046636 3 0.011
actin mediated cell contraction GO:0070252 12 0.010
t cell activation GO:0042110 99 0.010
cell growth GO:0016049 160 0.010
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.010
anion transport GO:0006820 161 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.010
mast cell degranulation GO:0043303 4 0.010
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.010
positive regulation of intracellular transport GO:0032388 104 0.010
protein localization to organelle GO:0033365 280 0.010
somatic muscle development GO:0007525 1 0.010
cell fate determination GO:0001709 3 0.010
blood vessel development GO:0001568 172 0.010
negative regulation of cellular component movement GO:0051271 106 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
glycoprotein biosynthetic process GO:0009101 91 0.010
positive regulation of secretion by cell GO:1903532 108 0.010
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.010
coagulation GO:0050817 78 0.010

PLEKHO2 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.027
disease of cellular proliferation DOID:14566 174 0.027
organ system cancer DOID:0050686 164 0.027
disease of metabolism DOID:0014667 295 0.015
inherited metabolic disorder DOID:655 242 0.015
sensory system disease DOID:0050155 203 0.014
nervous system disease DOID:863 431 0.014
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.012
central nervous system disease DOID:331 186 0.011
musculoskeletal system disease DOID:17 223 0.011
disease by infectious agent DOID:0050117 34 0.011