|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.527
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.500
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.454
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.434
|
Fly |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.424
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.423
|
Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.413
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.392
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.366
|
Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.349
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.287
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.283
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.273
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.258
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.208
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.195
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
9 |
0.187
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.183
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.177
|
Human Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.158
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.154
|
Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.135
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.133
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.119
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.113
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.109
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.106
|
Human Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.102
|
Fly |
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.098
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.098
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.097
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.095
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.093
|
|
|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
12 |
0.092
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.091
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.084
|
Fly |
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.082
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.080
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.074
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.074
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
11 |
0.071
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.068
|
Human Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.068
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.067
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.067
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.066
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.065
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.064
|
|
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.062
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.060
|
Human |
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.060
|
|
|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
0.060
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.059
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.056
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.054
|
Fly |
|
|
reproductive process
|
GO:0022414 |
106 |
0.053
|
Fly |
|
|
histone h2a monoubiquitination
|
GO:0035518 |
11 |
0.052
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.052
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.050
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.050
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.046
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.045
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.045
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.044
|
Human Mouse |
|
|
sex differentiation
|
GO:0007548 |
45 |
0.044
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.042
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
15 |
0.041
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.041
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.040
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.039
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.038
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.038
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.038
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.037
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.036
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.036
|
Fly |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.036
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.035
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.035
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.035
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.035
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.034
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.033
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.033
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.032
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.032
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.032
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.031
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.031
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.031
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.031
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.030
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.030
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.030
|
Human |
|
|
skin development
|
GO:0043588 |
76 |
0.030
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
0.030
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.029
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.029
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.027
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.027
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.027
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.027
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.026
|
Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.026
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.026
|
|
|
|
memory
|
GO:0007613 |
3 |
0.025
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.025
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.025
|
Human |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.024
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.024
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.024
|
Human Mouse |
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.023
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.023
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.023
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.023
|
Human |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.022
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.022
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.022
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.022
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.022
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.022
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.022
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.022
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.022
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.021
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.021
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.021
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.020
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.020
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.020
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.020
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.019
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.019
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.019
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.019
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.018
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.018
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.018
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.018
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.018
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.017
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.017
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.017
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.017
|
Fly |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.017
|
|
|
|
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna
|
GO:0000462 |
1 |
0.017
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.017
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.017
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.017
|
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.017
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.017
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.017
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.016
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.016
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.016
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.016
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.016
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.016
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.016
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.016
|
Fly |
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.016
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.015
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.015
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.015
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
6 |
0.015
|
Fly |
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.015
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.015
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.015
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.015
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.015
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.015
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.015
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.015
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.015
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.015
|
Human |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.015
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.014
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.014
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.014
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.014
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.014
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.014
|
Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.014
|
|
|
|
maturation of ssu rrna
|
GO:0030490 |
3 |
0.014
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.014
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.014
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.014
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.014
|
Fly |
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.013
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.013
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.013
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.013
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.013
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.013
|
Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.013
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.013
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.013
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.013
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.013
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.013
|
Fly |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.013
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.013
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
8 |
0.013
|
Human Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.013
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.013
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.013
|
Human Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.013
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.012
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.012
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.012
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.012
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.012
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.012
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.012
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.012
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.012
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.012
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.012
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.012
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.012
|
Fly |
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.012
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.012
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.012
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.012
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.012
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.011
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.011
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.011
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.011
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.011
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.011
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.011
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.011
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.011
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.011
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.011
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.011
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.011
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.011
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.011
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.011
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.011
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.011
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.011
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.011
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.011
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.011
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.011
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.010
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.010
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.010
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.010
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.010
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.010
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.010
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.010
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.010
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.010
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.010
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.010
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.010
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.010
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.010
|
Fly |