Homo sapiens

51 known processes

IFITM2

interferon induced transmembrane protein 2 (1-8D)

(Aliases: 1-8D)

IFITM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
entry into host GO:0044409 25 0.998
positive regulation of osteoblast differentiation GO:0045669 23 0.995
Human
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.988
entry into other organism involved in symbiotic interaction GO:0051828 25 0.964
type i interferon signaling pathway GO:0060337 11 0.937
Mouse
movement in host environment GO:0052126 25 0.891
regulation of viral transcription GO:0046782 34 0.890
Human
regulation of ossification GO:0030278 58 0.888
Human
negative regulation of locomotion GO:0040013 118 0.873
viral entry into host cell GO:0046718 24 0.847
regulation of cell migration GO:0030334 289 0.845
Human
interaction with host GO:0051701 42 0.788
negative regulation of cell migration GO:0030336 102 0.786
Human
viral gene expression GO:0019080 35 0.758
Human
regulation of locomotion GO:0040012 329 0.747
negative regulation of cellular component movement GO:0051271 106 0.722
Human
regulation of cell motility GO:2000145 299 0.706
Human
negative regulation of viral transcription GO:0032897 23 0.706
Human
regulation of viral genome replication GO:0045069 48 0.700
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.698
regulation of viral entry into host cell GO:0046596 17 0.695
regulation of cellular component movement GO:0051270 334 0.695
Human
multi organism metabolic process GO:0044033 41 0.677
Human
negative regulation of cell motility GO:2000146 104 0.661
Human
osteoblast differentiation GO:0001649 92 0.659
Human
entry into host cell GO:0030260 25 0.599
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.575
response to interferon beta GO:0035456 11 0.554
viral process GO:0016032 146 0.554
innate immune response GO:0045087 178 0.539
negative regulation of cell proliferation GO:0008285 228 0.533
Human Mouse
cellular response to type i interferon GO:0071357 12 0.529
Mouse
cytokine mediated signaling pathway GO:0019221 109 0.525
Mouse
negative regulation of multi organism process GO:0043901 92 0.522
viral transcription GO:0019083 35 0.512
Human
positive regulation of cell differentiation GO:0045597 211 0.498
Human
negative regulation of viral genome replication GO:0045071 35 0.495
ossification GO:0001503 121 0.469
Human
negative regulation of protein metabolic process GO:0051248 391 0.442
regulation of cell differentiation GO:0045595 393 0.410
Human
regulation of cytokine production GO:0001817 232 0.406
positive regulation of developmental process GO:0051094 314 0.404
Human
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.402
response to virus GO:0009615 126 0.401
regulation of viral process GO:0050792 103 0.378
negative regulation of hydrolase activity GO:0051346 182 0.348
response to type i interferon GO:0034340 14 0.344
Mouse
negative regulation of viral entry into host cell GO:0046597 12 0.314
regulation of multi organism process GO:0043900 157 0.313
response to other organism GO:0051707 261 0.311
response to interferon gamma GO:0034341 39 0.308
viral life cycle GO:0019058 132 0.302
immune effector process GO:0002252 159 0.302
Mouse
cellular response to cytokine stimulus GO:0071345 181 0.297
Mouse
multi organism cellular process GO:0044764 156 0.277
response to biotic stimulus GO:0009607 276 0.268
protein maturation GO:0051604 233 0.266
transition metal ion transport GO:0000041 23 0.261
cardiovascular system development GO:0072358 262 0.260
viral genome replication GO:0019079 50 0.259
negative regulation of cellular protein metabolic process GO:0032269 353 0.253
cardiac muscle tissue development GO:0048738 39 0.249
regulation of endopeptidase activity GO:0052548 170 0.242
positive regulation of ossification GO:0045778 32 0.234
Human
negative regulation of protein maturation GO:1903318 142 0.229
nucleoside phosphate catabolic process GO:1901292 412 0.218
detection of chemical stimulus GO:0009593 55 0.207
regulation of osteoblast differentiation GO:0045667 38 0.206
Human
regulation of proteolysis GO:0030162 293 0.205
immune response inhibiting signal transduction GO:0002765 4 0.199
response to cytokine GO:0034097 232 0.198
protein processing GO:0016485 226 0.197
negative regulation of protein processing GO:0010955 142 0.193
regulation of leukocyte mediated immunity GO:0002703 38 0.191
positive regulation of t cell tolerance induction GO:0002666 2 0.190
regulation of dendritic cell differentiation GO:2001198 3 0.180
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.172
negative regulation of peptidase activity GO:0010466 91 0.152
t cell tolerance induction GO:0002517 4 0.151
regulation of apoptotic signaling pathway GO:2001233 175 0.146
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.145
negative regulation of endopeptidase activity GO:0010951 84 0.144
negative regulation of viral process GO:0048525 66 0.140
heart development GO:0007507 95 0.136
retina homeostasis GO:0001895 42 0.130
negative regulation of multicellular organismal process GO:0051241 317 0.129
negative regulation of immune response GO:0050777 40 0.123
defense response GO:0006952 315 0.121
cation transport GO:0006812 331 0.110
metal ion transport GO:0030001 272 0.104
negative regulation of leukocyte mediated immunity GO:0002704 14 0.103
response to external biotic stimulus GO:0043207 261 0.102
immune response GO:0006955 307 0.098
defense response to other organism GO:0098542 129 0.097
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 24 0.095
epinephrine secretion GO:0048242 1 0.092
defense response to virus GO:0051607 71 0.088
Mouse
negative regulation of immune effector process GO:0002698 38 0.083
negative regulation of catalytic activity GO:0043086 335 0.082
catecholamine secretion GO:0050432 1 0.082
response to interferon alpha GO:0035455 11 0.080
cell adhesion GO:0007155 325 0.075
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.075
interspecies interaction between organisms GO:0044419 156 0.072
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.071
positive regulation of programmed cell death GO:0043068 249 0.068
positive regulation of cytokine production GO:0001819 167 0.068
striated muscle tissue development GO:0014706 59 0.066
mapk cascade GO:0000165 288 0.064
purine nucleoside catabolic process GO:0006152 398 0.064
circulatory system development GO:0072359 262 0.060
nucleoside phosphate biosynthetic process GO:1901293 109 0.060
muscle structure development GO:0061061 98 0.059
cardiac muscle cell differentiation GO:0055007 15 0.059
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.058
negative regulation of protein activation cascade GO:2000258 7 0.058
i kappab kinase nf kappab signaling GO:0007249 166 0.054
regulation of intracellular transport of viral material GO:1901252 2 0.054
epinephrine transport GO:0048241 1 0.054
positive regulation of mapk cascade GO:0043410 190 0.053
positive regulation of hydrolase activity GO:0051345 331 0.053
positive regulation of immune system process GO:0002684 283 0.053
inflammatory response GO:0006954 79 0.049
regulation of actin filament based process GO:0032970 141 0.048
cytoplasmic transport GO:0016482 379 0.048
regulation of complement activation lectin pathway GO:0001868 2 0.047
sensory perception of chemical stimulus GO:0007606 38 0.047
regulation of peptidase activity GO:0052547 180 0.047
ribonucleoside catabolic process GO:0042454 406 0.047
apoptotic signaling pathway GO:0097190 268 0.046
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.045
growth GO:0040007 202 0.044
response to oxygen containing compound GO:1901700 369 0.044
leukocyte activation GO:0045321 164 0.044
positive regulation of peptidase activity GO:0010952 88 0.042
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.041
regulation of protein maturation GO:1903317 150 0.041
detection of biotic stimulus GO:0009595 21 0.041
muscle tissue development GO:0060537 62 0.040
regulation of vasculogenesis GO:2001212 3 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
regulation of purine nucleotide catabolic process GO:0033121 205 0.039
positive regulation of endopeptidase activity GO:0010950 84 0.039
nucleoside triphosphate catabolic process GO:0009143 394 0.038
positive regulation of protein kinase activity GO:0045860 190 0.037
regulation of ligase activity GO:0051340 29 0.037
blood vessel morphogenesis GO:0048514 162 0.036
biological adhesion GO:0022610 331 0.035
guanosine containing compound metabolic process GO:1901068 244 0.035
negative regulation of defense response GO:0031348 47 0.035
regulation of intracellular transport GO:0032386 195 0.034
regulation of angiogenesis GO:0045765 92 0.034
positive regulation of phosphorylation GO:0042327 394 0.034
purine containing compound catabolic process GO:0072523 411 0.032
negative regulation of dendritic cell differentiation GO:2001199 2 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
regulation of kinase activity GO:0043549 314 0.032
purine nucleoside triphosphate catabolic process GO:0009146 392 0.032
ribonucleoside triphosphate catabolic process GO:0009203 391 0.031
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.031
negative regulation of catabolic process GO:0009895 104 0.031
nuclear transport GO:0051169 179 0.031
regulation of purine nucleotide metabolic process GO:1900542 264 0.031
regulation of protein catabolic process GO:0042176 155 0.031
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independent GO:0002486 3 0.031
extrinsic apoptotic signaling pathway GO:0097191 119 0.029
zymogen activation GO:0031638 70 0.029
gtp catabolic process GO:0006184 237 0.029
positive regulation of t cell activation GO:0050870 54 0.028
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.028
iron ion import into cell GO:0097459 2 0.028
regulation of cytoskeleton organization GO:0051493 177 0.028
response to wounding GO:0009611 168 0.028
negative regulation of complement activation lectin pathway GO:0001869 2 0.028
nucleotide catabolic process GO:0009166 408 0.028
positive regulation of tolerance induction GO:0002645 2 0.027
intracellular protein transport GO:0006886 270 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
system process GO:0003008 349 0.027
detection of external biotic stimulus GO:0098581 19 0.027
cytokine production involved in immune response GO:0002367 27 0.026
regulation of protein processing GO:0070613 150 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.025
purine ribonucleoside catabolic process GO:0046130 398 0.025
regulation of growth GO:0040008 165 0.025
positive regulation of interferon gamma production GO:0032729 26 0.025
regulation of leukocyte activation GO:0002694 115 0.025
acute inflammatory response GO:0002526 21 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.024
vasculature development GO:0001944 181 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
cellular response to lipid GO:0071396 127 0.023
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.023
adaptive immune response GO:0002250 49 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
post embryonic development GO:0009791 2 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.022
regulation of mapk cascade GO:0043408 262 0.022
positive regulation of organelle organization GO:0010638 195 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
regulation of gtpase activity GO:0043087 180 0.021
regulation of vasculature development GO:1901342 97 0.021
regulation of protein kinase activity GO:0045859 289 0.021
regulation of leukocyte proliferation GO:0070663 67 0.021
negative regulation of developmental process GO:0051093 247 0.021
nucleoside catabolic process GO:0009164 408 0.021
regulation of lymphocyte mediated immunity GO:0002706 33 0.021
peptidyl tyrosine modification GO:0018212 170 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
negative regulation of cell death GO:0060548 345 0.021
positive regulation of cellular component organization GO:0051130 376 0.020
mononuclear cell proliferation GO:0032943 71 0.020
detection of stimulus GO:0051606 85 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
ribonucleotide catabolic process GO:0009261 405 0.019
mitochondrion organization GO:0007005 156 0.019
regulation of lymphocyte proliferation GO:0050670 64 0.019
regulation of innate immune response GO:0045088 97 0.019
regulation of response to wounding GO:1903034 101 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
organic hydroxy compound transport GO:0015850 63 0.019
actin filament organization GO:0007015 128 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
detection of chemical stimulus involved in sensory perception of taste GO:0050912 31 0.019
positive regulation of adaptive immune response GO:0002821 21 0.019
gtp metabolic process GO:0046039 239 0.019
cell growth GO:0016049 160 0.019
regulation of erk1 and erk2 cascade GO:0070372 99 0.019
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.019
renal system process involved in regulation of blood volume GO:0001977 4 0.018
regulation of tolerance induction GO:0002643 4 0.018
secretion by cell GO:0032940 226 0.018
response to hormone GO:0009725 175 0.018
cell activation GO:0001775 213 0.018
negative regulation of innate immune response GO:0045824 18 0.018
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
positive regulation of locomotion GO:0040017 186 0.018
actin filament based process GO:0030029 224 0.018
leukocyte mediated cytotoxicity GO:0001909 27 0.018
t cell activation GO:0042110 99 0.017
angiogenesis GO:0001525 147 0.017
positive regulation of cell death GO:0010942 263 0.017
single organism membrane organization GO:0044802 268 0.017
endothelial cell migration GO:0043542 86 0.017
protein activation cascade GO:0072376 22 0.017
neurological system process GO:0050877 163 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
blood vessel development GO:0001568 172 0.017
immune system development GO:0002520 195 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
erk1 and erk2 cascade GO:0070371 104 0.016
regulation of immune response GO:0050776 201 0.016
positive regulation of lymphocyte activation GO:0051251 73 0.016
organophosphate catabolic process GO:0046434 430 0.016
regulation of protein serine threonine kinase activity GO:0071900 179 0.016
regulation of natural killer cell mediated immunity GO:0002715 16 0.016
regulation of jnk cascade GO:0046328 73 0.016
regulation of cell adhesion GO:0030155 166 0.015
inorganic ion import into cell GO:0099587 2 0.015
regulation of inflammatory response GO:0050727 46 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
regulation of transferase activity GO:0051338 355 0.015
negative regulation of proteolysis GO:0045861 132 0.015
regulation of binding GO:0051098 111 0.015
positive regulation of kinase activity GO:0033674 204 0.015
production of molecular mediator of immune response GO:0002440 37 0.015
regulation of cell killing GO:0031341 22 0.015
positive regulation of regulatory t cell differentiation GO:0045591 3 0.015
cardiac ventricle morphogenesis GO:0003208 20 0.015
ras protein signal transduction GO:0007265 73 0.015
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.015
negative regulation of trophoblast cell migration GO:1901164 3 0.015
positive regulation of leukocyte activation GO:0002696 80 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
positive regulation of transferase activity GO:0051347 227 0.014
negative regulation of cytokine production GO:0001818 82 0.014
cell development GO:0048468 328 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
determination of adult lifespan GO:0008340 2 0.014
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 2 0.014
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.014
single organism cellular localization GO:1902580 332 0.014
regulation of nucleotide biosynthetic process GO:0030808 50 0.014
regulation of homeostatic process GO:0032844 121 0.014
multicellular organismal aging GO:0010259 3 0.014
epithelial cell migration GO:0010631 119 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
membrane organization GO:0061024 292 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
positive regulation of cell activation GO:0050867 81 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
regeneration GO:0031099 4 0.013
regulation of acute inflammatory response GO:0002673 13 0.013
interferon gamma production GO:0032609 39 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
secretion GO:0046903 254 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.013
actin filament based movement GO:0030048 17 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
muscle cell differentiation GO:0042692 63 0.013
protein catabolic process GO:0030163 325 0.013
regulation of mononuclear cell proliferation GO:0032944 65 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
regulation of cell cycle GO:0051726 393 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
single organism cell adhesion GO:0098602 179 0.013
lymphocyte activation GO:0046649 133 0.013
nitrogen compound transport GO:0071705 191 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.013
regulation of gtp catabolic process GO:0033124 180 0.012
regulation of stress activated mapk cascade GO:0032872 84 0.012
negative regulation of protein modification process GO:0031400 200 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
plasma membrane organization GO:0007009 115 0.012
cellular amine metabolic process GO:0044106 41 0.012
amine metabolic process GO:0009308 44 0.012
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.012
regulation of body fluid levels GO:0050878 99 0.012
regulation of cell activation GO:0050865 125 0.012
response to bacterium GO:0009617 144 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
heart morphogenesis GO:0003007 48 0.012
negative regulation of leukocyte activation GO:0002695 26 0.012
response to abiotic stimulus GO:0009628 336 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
transmembrane transport GO:0055085 399 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
cardiocyte differentiation GO:0035051 23 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
lymphocyte proliferation GO:0046651 70 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
regulation of protein stability GO:0031647 87 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
negative regulation of transport GO:0051051 176 0.011
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.011
anatomical structure homeostasis GO:0060249 100 0.011
hemopoiesis GO:0030097 180 0.011
positive regulation of immune response GO:0050778 159 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
regulation of t cell tolerance induction GO:0002664 4 0.011
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
striated muscle cell differentiation GO:0051146 43 0.011
interleukin 6 production GO:0032635 37 0.011
cytokine production GO:0001816 247 0.011
t cell proliferation GO:0042098 45 0.011
negative regulation of leukocyte proliferation GO:0070664 16 0.011
activation of cysteine type endopeptidase activity GO:0097202 57 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
regulation of membrane potential GO:0042391 95 0.011
ameboidal type cell migration GO:0001667 135 0.010
sensory perception GO:0007600 103 0.010
detection of bacterium GO:0016045 13 0.010
multicellular organismal homeostasis GO:0048871 67 0.010
t cell mediated cytotoxicity GO:0001913 9 0.010
stress fiber assembly GO:0043149 40 0.010
import into cell GO:0098657 2 0.010
cellular amino acid metabolic process GO:0006520 116 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
regulation of protein transport GO:0051223 213 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010

IFITM2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.071
skin disease DOID:37 33 0.044
integumentary system disease DOID:16 43 0.044
sensory system disease DOID:0050155 203 0.020
nervous system disease DOID:863 431 0.020
disease by infectious agent DOID:0050117 34 0.018
viral infectious disease DOID:934 13 0.018
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013