Homo sapiens

126 known processes

ARFGAP3

ADP-ribosylation factor GTPase activating protein 3

(Aliases: FLJ45618,ARFGAP1)

ARFGAP3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 0.398
vesicle mediated transport GO:0016192 371 0.376
secretion GO:0046903 254 0.316
golgi vesicle transport GO:0048193 80 0.311
positive regulation of transport GO:0051050 336 0.218
membrane organization GO:0061024 292 0.216
glycoprotein metabolic process GO:0009100 110 0.200
gtp metabolic process GO:0046039 239 0.189
ribonucleoside catabolic process GO:0042454 406 0.168
post embryonic development GO:0009791 2 0.167
regulation of secretion by cell GO:1903530 177 0.161
cytoplasmic transport GO:0016482 379 0.142
oogenesis GO:0048477 2 0.142
carbohydrate derivative biosynthetic process GO:1901137 207 0.138
carbohydrate metabolic process GO:0005975 207 0.127
female gamete generation GO:0007292 2 0.123
regulation of secretion GO:0051046 194 0.120
regulation of cell motility GO:2000145 299 0.115
positive regulation of secretion by cell GO:1903532 108 0.110
single organism membrane organization GO:0044802 268 0.107
single organism carbohydrate metabolic process GO:0044723 193 0.105
negative regulation of multicellular organismal process GO:0051241 317 0.102
glycoprotein biosynthetic process GO:0009101 91 0.091
single organism cellular localization GO:1902580 332 0.085
guanosine containing compound metabolic process GO:1901068 244 0.082
regulation of protein secretion GO:0050708 86 0.079
nucleotide catabolic process GO:0009166 408 0.074
ribonucleoside triphosphate metabolic process GO:0009199 412 0.072
purine ribonucleoside catabolic process GO:0046130 398 0.072
secretion by cell GO:0032940 226 0.070
purine nucleotide catabolic process GO:0006195 405 0.068
protein localization to organelle GO:0033365 280 0.066
chondroitin sulfate proteoglycan metabolic process GO:0050654 10 0.065
glycosyl compound catabolic process GO:1901658 413 0.065
gtp catabolic process GO:0006184 237 0.065
cation transport GO:0006812 331 0.064
maintenance of location GO:0051235 112 0.064
purine containing compound catabolic process GO:0072523 411 0.064
golgi organization GO:0007030 38 0.062
multicellular organismal aging GO:0010259 3 0.060
sulfur compound metabolic process GO:0006790 101 0.060
nucleoside triphosphate metabolic process GO:0009141 422 0.057
regulation of establishment of protein localization GO:0070201 242 0.056
macromolecule glycosylation GO:0043413 63 0.056
regulation of vesicle mediated transport GO:0060627 130 0.054
regulation of protein localization GO:0032880 296 0.051
sulfur compound biosynthetic process GO:0044272 38 0.051
positive regulation of phosphorylation GO:0042327 394 0.050
chemical homeostasis GO:0048878 306 0.049
regulation of cellular component biogenesis GO:0044087 281 0.049
regulation of cellular component movement GO:0051270 334 0.049
vesicle organization GO:0016050 62 0.049
purine ribonucleoside metabolic process GO:0046128 437 0.047
post golgi vesicle mediated transport GO:0006892 36 0.047
response to disaccharide GO:0034285 1 0.046
cellular macromolecular complex assembly GO:0034622 324 0.046
lipid metabolic process GO:0006629 381 0.046
ribonucleoside triphosphate catabolic process GO:0009203 391 0.045
ras protein signal transduction GO:0007265 73 0.045
nucleotide sugar metabolic process GO:0009225 8 0.045
cellular macromolecule catabolic process GO:0044265 380 0.045
endosomal transport GO:0016197 129 0.044
positive regulation of secretion GO:0051047 116 0.043
positive regulation of cellular component organization GO:0051130 376 0.042
cell projection organization GO:0030030 252 0.042
determination of adult lifespan GO:0008340 2 0.041
monocarboxylic acid metabolic process GO:0032787 185 0.040
cellular lipid metabolic process GO:0044255 303 0.040
positive regulation of hydrolase activity GO:0051345 331 0.040
nucleoside phosphate catabolic process GO:1901292 412 0.040
purine nucleoside catabolic process GO:0006152 398 0.039
purine nucleoside triphosphate metabolic process GO:0009144 412 0.039
small gtpase mediated signal transduction GO:0007264 78 0.038
protein catabolic process GO:0030163 325 0.038
biological adhesion GO:0022610 331 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.038
endomembrane system organization GO:0010256 196 0.038
cellular cation homeostasis GO:0030003 163 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
defense response GO:0006952 315 0.035
regulation of cell migration GO:0030334 289 0.035
positive regulation of cellular component movement GO:0051272 181 0.035
guanosine containing compound catabolic process GO:1901069 239 0.034
cell development GO:0048468 328 0.034
regulation of proteolysis GO:0030162 293 0.034
transmembrane transport GO:0055085 399 0.034
establishment of protein localization to membrane GO:0090150 121 0.033
cellular ketone metabolic process GO:0042180 80 0.033
regulation of cell cycle GO:0051726 393 0.032
lipid biosynthetic process GO:0008610 177 0.032
positive regulation of protein transport GO:0051222 135 0.032
cell adhesion GO:0007155 325 0.032
positive regulation of protein secretion GO:0050714 60 0.032
response to biotic stimulus GO:0009607 276 0.032
positive regulation of cell motility GO:2000147 177 0.031
enzyme linked receptor protein signaling pathway GO:0007167 303 0.031
muscle structure development GO:0061061 98 0.031
cellular response to endogenous stimulus GO:0071495 336 0.031
actin filament based process GO:0030029 224 0.030
response to wounding GO:0009611 168 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
amine metabolic process GO:0009308 44 0.030
membrane budding GO:0006900 28 0.030
positive regulation of homeostatic process GO:0032846 47 0.030
positive regulation of keratinocyte migration GO:0051549 4 0.030
regulation of protein transport GO:0051223 213 0.030
small molecule biosynthetic process GO:0044283 157 0.030
fatty acid metabolic process GO:0006631 115 0.029
positive regulation of immune system process GO:0002684 283 0.029
intracellular protein transport GO:0006886 270 0.029
immune response GO:0006955 307 0.028
regulation of response to external stimulus GO:0032101 222 0.028
system process GO:0003008 349 0.028
positive regulation of cell migration GO:0030335 172 0.028
epithelial cell differentiation GO:0030855 141 0.028
cellular protein complex assembly GO:0043623 188 0.028
negative regulation of apoptotic process GO:0043066 316 0.027
cellular amine metabolic process GO:0044106 41 0.027
protein localization to membrane GO:0072657 160 0.027
organophosphate biosynthetic process GO:0090407 163 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.027
actin cytoskeleton organization GO:0030036 207 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.027
positive regulation of developmental process GO:0051094 314 0.026
response to endoplasmic reticulum stress GO:0034976 49 0.026
regulation of apoptotic signaling pathway GO:2001233 175 0.026
positive regulation of catabolic process GO:0009896 310 0.026
metencephalon development GO:0022037 2 0.026
regulation of reactive oxygen species metabolic process GO:2000377 41 0.025
regulation of locomotion GO:0040012 329 0.025
regulation of transferase activity GO:0051338 355 0.025
apoptotic signaling pathway GO:0097190 268 0.025
positive regulation of apoptotic process GO:0043065 246 0.025
negative regulation of cell death GO:0060548 345 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
cholesterol homeostasis GO:0042632 28 0.025
nucleoside triphosphate catabolic process GO:0009143 394 0.025
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.024
regulation of cellular response to stress GO:0080135 244 0.024
receptor metabolic process GO:0043112 81 0.024
nucleotide biosynthetic process GO:0009165 109 0.024
regulation of intracellular transport GO:0032386 195 0.024
ion transmembrane transport GO:0034220 338 0.024
cellular amino acid metabolic process GO:0006520 116 0.023
golgi ribbon formation GO:0090161 3 0.023
regulation of cell cycle process GO:0010564 266 0.023
positive regulation of mapk cascade GO:0043410 190 0.023
cation homeostasis GO:0055080 189 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
sterol homeostasis GO:0055092 28 0.022
cellular response to lipid GO:0071396 127 0.022
leukocyte migration GO:0050900 107 0.022
cell substrate adhesion GO:0031589 132 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
modification dependent macromolecule catabolic process GO:0043632 212 0.022
cell chemotaxis GO:0060326 112 0.022
reactive oxygen species metabolic process GO:0072593 75 0.021
ion homeostasis GO:0050801 230 0.021
organophosphate catabolic process GO:0046434 430 0.021
cellular component morphogenesis GO:0032989 314 0.021
positive regulation of gtp catabolic process GO:0033126 166 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
hindbrain development GO:0030902 3 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
regulation of defense response GO:0031347 154 0.020
er to golgi vesicle mediated transport GO:0006888 19 0.020
protein ubiquitination GO:0016567 314 0.020
positive regulation of cell differentiation GO:0045597 211 0.020
negative regulation of transport GO:0051051 176 0.020
cellular ion homeostasis GO:0006873 168 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
regulation of gtpase activity GO:0043087 180 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
response to topologically incorrect protein GO:0035966 29 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
nitrogen compound transport GO:0071705 191 0.020
metal ion transport GO:0030001 272 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.019
positive regulation of cell proliferation GO:0008284 301 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.019
cellular protein catabolic process GO:0044257 261 0.019
striated muscle myosin thick filament assembly GO:0071688 2 0.019
protein oligomerization GO:0051259 173 0.019
modification dependent protein catabolic process GO:0019941 209 0.019
establishment of protein localization to plasma membrane GO:0090002 68 0.019
protein localization to plasma membrane GO:0072659 93 0.019
segmentation GO:0035282 4 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
amino sugar metabolic process GO:0006040 15 0.019
regulation of hormone secretion GO:0046883 57 0.019
inorganic cation transmembrane transport GO:0098662 194 0.018
lipid localization GO:0010876 106 0.018
cell projection assembly GO:0030031 126 0.018
cell division GO:0051301 168 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
mapk cascade GO:0000165 288 0.018
regulation of small gtpase mediated signal transduction GO:0051056 156 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
blood coagulation GO:0007596 76 0.018
response to oxygen containing compound GO:1901700 369 0.018
protein glycosylation GO:0006486 62 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
neutrophil mediated immunity GO:0002446 4 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
alcohol metabolic process GO:0006066 114 0.018
regulation of body fluid levels GO:0050878 99 0.017
regulation of leukocyte migration GO:0002685 63 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
protein targeting to membrane GO:0006612 42 0.017
plasma membrane organization GO:0007009 115 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
organic acid biosynthetic process GO:0016053 97 0.017
adult locomotory behavior GO:0008344 1 0.017
protein homooligomerization GO:0051260 100 0.017
leukocyte chemotaxis GO:0030595 76 0.017
negative regulation of protein metabolic process GO:0051248 391 0.017
response to fungus GO:0009620 4 0.017
regulation of binding GO:0051098 111 0.017
glucose metabolic process GO:0006006 45 0.017
innate immune response GO:0045087 178 0.017
regulation of immune response GO:0050776 201 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
regulation of cell projection organization GO:0031344 107 0.016
nervous system development GO:0007399 293 0.016
single organism cell adhesion GO:0098602 179 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
regulation of multi organism process GO:0043900 157 0.016
protein targeting GO:0006605 187 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
amide transport GO:0042886 76 0.016
response to organonitrogen compound GO:0010243 156 0.016
cytokine production GO:0001816 247 0.016
circulatory system development GO:0072359 262 0.016
aminoglycan metabolic process GO:0006022 39 0.016
membrane fusion GO:0061025 43 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
glycosylation GO:0070085 71 0.015
protein secretion GO:0009306 98 0.015
cellular response to glucocorticoid stimulus GO:0071385 4 0.015
lipid homeostasis GO:0055088 39 0.015
rho protein signal transduction GO:0007266 26 0.015
organic anion transport GO:0015711 103 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
regulation of ossification GO:0030278 58 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
mitochondrion organization GO:0007005 156 0.015
anion transport GO:0006820 161 0.015
positive regulation of phagocytosis engulfment GO:0060100 1 0.015
cell activation GO:0001775 213 0.015
hexose metabolic process GO:0019318 55 0.015
regulation of leukocyte chemotaxis GO:0002688 46 0.015
oxidation reduction process GO:0055114 396 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
peptide secretion GO:0002790 51 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
cell cycle phase transition GO:0044770 173 0.014
regulation of cytokine production GO:0001817 232 0.014
positive regulation of transferase activity GO:0051347 227 0.014
cation transmembrane transport GO:0098655 238 0.014
regulation of protein catabolic process GO:0042176 155 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
regulation of keratinocyte migration GO:0051547 4 0.014
leukocyte activation GO:0045321 164 0.014
metal ion homeostasis GO:0055065 169 0.014
positive regulation of organelle organization GO:0010638 195 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
regulation of cellular amine metabolic process GO:0033238 11 0.014
coagulation GO:0050817 78 0.014
ossification GO:0001503 121 0.014
epithelium development GO:0060429 227 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.014
response to external biotic stimulus GO:0043207 261 0.014
endocytosis GO:0006897 159 0.014
neuromuscular junction development GO:0007528 3 0.014
organelle assembly GO:0070925 176 0.013
regulation of hormone levels GO:0010817 125 0.013
myosin filament assembly GO:0031034 2 0.013
nucleoside catabolic process GO:0009164 408 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
monosaccharide metabolic process GO:0005996 74 0.013
embryonic neurocranium morphogenesis GO:0048702 1 0.013
myosin filament organization GO:0031033 2 0.013
response to lipid GO:0033993 206 0.013
chondrocyte development GO:0002063 1 0.013
mitotic cell cycle GO:0000278 326 0.013
wound healing GO:0042060 115 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
hemopoiesis GO:0030097 180 0.013
transition metal ion homeostasis GO:0055076 31 0.013
bone mineralization GO:0030282 34 0.013
mitotic cell cycle process GO:1903047 286 0.013
sequestering of calcium ion GO:0051208 17 0.013
positive regulation of cell death GO:0010942 263 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
positive regulation of exocytosis GO:0045921 35 0.013
protein autophosphorylation GO:0046777 123 0.013
regulation of neurotransmitter secretion GO:0046928 3 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
rac protein signal transduction GO:0016601 12 0.013
regulation of protein complex assembly GO:0043254 147 0.013
response to growth factor GO:0070848 205 0.013
memory GO:0007613 3 0.013
divalent inorganic cation transport GO:0072511 158 0.013
exocytosis GO:0006887 71 0.012
inner ear morphogenesis GO:0042472 4 0.012
cerebellum development GO:0021549 2 0.012
regulation of cell differentiation GO:0045595 393 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
glycosaminoglycan metabolic process GO:0030203 35 0.012
compound eye development GO:0048749 1 0.012
negative regulation of immune system process GO:0002683 136 0.012
calcium ion transport GO:0006816 147 0.012
growth hormone secretion GO:0030252 4 0.012
regulation of cell development GO:0060284 161 0.012
cellular response to topologically incorrect protein GO:0035967 19 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
response to drug GO:0042493 81 0.012
cellular carbohydrate metabolic process GO:0044262 84 0.012
maintenance of protein location GO:0045185 57 0.012
response to hormone GO:0009725 175 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
regulation of mapk cascade GO:0043408 262 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
multi organism cellular process GO:0044764 156 0.012
proteoglycan biosynthetic process GO:0030166 20 0.012
regulation of kinase activity GO:0043549 314 0.012
positive regulation of locomotion GO:0040017 186 0.012
growth GO:0040007 202 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
cellular biogenic amine metabolic process GO:0006576 34 0.012
regulation of cholesterol homeostasis GO:2000188 2 0.012
reproductive process GO:0022414 106 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.011
regulation of glucose metabolic process GO:0010906 28 0.011
regulation of cell activation GO:0050865 125 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
vesicle targeting rough er to cis golgi GO:0048207 2 0.011
autophagy GO:0006914 88 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
cell growth GO:0016049 160 0.011
retina vasculature development in camera type eye GO:0061298 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
neural crest cell migration GO:0001755 2 0.011
response to nutrient levels GO:0031667 81 0.011
positive regulation of kinase activity GO:0033674 204 0.011
response to metal ion GO:0010038 84 0.011
aminoglycan biosynthetic process GO:0006023 29 0.011
localization within membrane GO:0051668 14 0.011
divalent metal ion transport GO:0070838 152 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
regulation of protein binding GO:0043393 66 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
positive regulation of organ growth GO:0046622 2 0.011
positive regulation of cytokine production GO:0001819 167 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.011
defense response to other organism GO:0098542 129 0.011
response to inorganic substance GO:0010035 127 0.011
neural tube closure GO:0001843 3 0.011
blood vessel morphogenesis GO:0048514 162 0.011
regulation of exocytosis GO:0017157 46 0.011
regulation of low density lipoprotein particle receptor biosynthetic process GO:0045714 4 0.011
behavior GO:0007610 112 0.011
positive regulation of proteolysis GO:0045862 142 0.011
maintenance of location in cell GO:0051651 62 0.010
fibroblast proliferation GO:0048144 33 0.010
lipid transport GO:0006869 90 0.010
regulation of generation of precursor metabolites and energy GO:0043467 27 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
regulation of cell adhesion GO:0030155 166 0.010
erk1 and erk2 cascade GO:0070371 104 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
embryo development GO:0009790 123 0.010
negative regulation of locomotion GO:0040013 118 0.010
peptide hormone secretion GO:0030072 50 0.010
receptor mediated endocytosis GO:0006898 84 0.010
peptidyl tyrosine modification GO:0018212 170 0.010

ARFGAP3 disease predictions

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 118 0.061
sensory system disease DOID:0050155 203 0.061
eye and adnexa disease DOID:1492 150 0.061
nervous system disease DOID:863 431 0.061
eye disease DOID:5614 149 0.061
disease of metabolism DOID:0014667 295 0.025
retinal degeneration DOID:8466 89 0.019
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
organ system cancer DOID:0050686 164 0.017
central nervous system disease DOID:331 186 0.011
musculoskeletal system disease DOID:17 223 0.010
connective tissue disease DOID:65 109 0.010