Homo sapiens

0 known processes

U2AF1

U2 small nuclear RNA auxiliary factor 1

(Aliases: FP793,DKFZp313J1712,U2AFBP,RNU2AF1,RN,U2AF35)

U2AF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna splicing via spliceosome GO:0000398 89 1.000
Fly
mrna processing GO:0006397 133 1.000
Fly
mrna metabolic process GO:0016071 175 1.000
Fly
spliceosomal complex assembly GO:0000245 17 1.000
rna splicing GO:0008380 131 1.000
Fly
rna splicing via transesterification reactions GO:0000375 90 1.000
Fly
regulation of meiotic cell cycle GO:0051445 4 0.999
post embryonic development GO:0009791 2 0.994
Worm
regulation of meiosis GO:0040020 3 0.994
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.991
Fly
cellular macromolecular complex assembly GO:0034622 324 0.989
reproductive process GO:0022414 106 0.949
Worm
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.945
Fly
ribonucleoprotein complex biogenesis GO:0022613 116 0.945
regulation of mrna metabolic process GO:1903311 53 0.938
Fly
regulation of mrna splicing via spliceosome GO:0048024 32 0.931
Fly
ribonucleoprotein complex assembly GO:0022618 78 0.929
ribonucleoprotein complex subunit organization GO:0071826 81 0.903
regulation of mrna processing GO:0050684 48 0.900
Fly
regulation of cell cycle GO:0051726 393 0.886
rna processing GO:0006396 255 0.884
Fly
regulation of cell cycle process GO:0010564 266 0.879
phagocytosis recognition GO:0006910 3 0.877
mrna splice site selection GO:0006376 7 0.838
oogenesis GO:0048477 2 0.801
regulation of nuclear division GO:0051783 65 0.724
epithelial cell proliferation involved in lung morphogenesis GO:0060502 3 0.722
meiotic nuclear division GO:0007126 10 0.708
sex differentiation GO:0007548 45 0.706
Worm
embryo development GO:0009790 123 0.589
Worm
cell development GO:0048468 328 0.536
negative regulation of mrna processing GO:0050686 12 0.500
female gamete generation GO:0007292 2 0.492
embryo development ending in birth or egg hatching GO:0009792 34 0.434
Worm
endocytosis GO:0006897 159 0.431
nuclear division GO:0000280 128 0.402
regulation of mapk cascade GO:0043408 262 0.372
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.366
mitotic cell cycle GO:0000278 326 0.314
Fly
cell division GO:0051301 168 0.300
growth GO:0040007 202 0.292
development of primary sexual characteristics GO:0045137 35 0.290
Worm
blastocyst development GO:0001824 3 0.273
regulation of rna splicing GO:0043484 62 0.260
Fly
mitotic cell cycle process GO:1903047 286 0.236
Fly
negative regulation of epidermal cell differentiation GO:0045605 4 0.236
cell competition in a multicellular organism GO:0035212 1 0.234
multi organism reproductive process GO:0044703 54 0.232
female sex determination GO:0030237 1 0.218
meiotic cell cycle GO:0051321 13 0.217
anterior posterior axis specification embryo GO:0008595 2 0.216
mapk cascade GO:0000165 288 0.213
defense response GO:0006952 315 0.206
vesicle mediated transport GO:0016192 371 0.202
multicellular organismal reproductive process GO:0048609 40 0.191
regulation of cell cycle phase transition GO:1901987 126 0.183
regulation of growth rate GO:0040009 1 0.180
leukocyte activation GO:0045321 164 0.179
negative regulation of rna splicing GO:0033119 15 0.178
reproduction GO:0000003 63 0.177
Worm
angiogenesis GO:0001525 147 0.176
ras protein signal transduction GO:0007265 73 0.175
anterior posterior axis specification GO:0009948 2 0.166
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 2 0.163
cell activation GO:0001775 213 0.158
nervous system development GO:0007399 293 0.155
protein demethylation GO:0006482 17 0.152
gonad development GO:0008406 34 0.149
Worm
defense response to other organism GO:0098542 129 0.145
regulation of astrocyte differentiation GO:0048710 3 0.145
receptor mediated endocytosis GO:0006898 84 0.145
erk1 and erk2 cascade GO:0070371 104 0.140
regulation of cellular response to stress GO:0080135 244 0.140
divalent metal ion transport GO:0070838 152 0.130
cellular ion homeostasis GO:0006873 168 0.129
blastoderm segmentation GO:0007350 2 0.127
circulatory system development GO:0072359 262 0.127
spliceosomal snrnp assembly GO:0000387 28 0.124
lymphocyte activation GO:0046649 133 0.120
organelle fission GO:0048285 149 0.120
oocyte differentiation GO:0009994 2 0.116
protein localization to organelle GO:0033365 280 0.115
nucleocytoplasmic transport GO:0006913 176 0.115
regulation of oocyte development GO:0060281 1 0.114
reproductive system development GO:0061458 56 0.113
Worm
neurogenesis GO:0022008 169 0.108
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.107
tripartite regional subdivision GO:0007351 2 0.105
mrna 5 splice site recognition GO:0000395 3 0.102
cellular cation homeostasis GO:0030003 163 0.101
segmentation GO:0035282 4 0.099
regulation of glial cell differentiation GO:0045685 3 0.098
cellular calcium ion homeostasis GO:0006874 117 0.097
regulation of nucleocytoplasmic transport GO:0046822 98 0.096
single organism reproductive process GO:0044702 98 0.095
Worm
positive regulation of mapk cascade GO:0043410 190 0.095
negative regulation of mrna metabolic process GO:1903312 15 0.092
positive regulation of nucleobase containing compound transport GO:0032241 1 0.091
immune system development GO:0002520 195 0.088
epithelium development GO:0060429 227 0.083
sprouting angiogenesis GO:0002040 29 0.081
cellular metal ion homeostasis GO:0006875 146 0.075
t cell differentiation in thymus GO:0033077 4 0.075
lung development GO:0030324 20 0.075
positive regulation of mrna metabolic process GO:1903313 19 0.075
positive regulation of programmed cell death GO:0043068 249 0.075
microtubule cytoskeleton organization GO:0000226 176 0.075
Fly
small gtpase mediated signal transduction GO:0007264 78 0.074
spliceosomal tri snrnp complex assembly GO:0000244 7 0.074
astrocyte differentiation GO:0048708 4 0.074
reproductive structure development GO:0048608 55 0.074
Worm
protein hydroxylation GO:0018126 9 0.074
erythrocyte homeostasis GO:0034101 31 0.073
cellular homeostasis GO:0019725 196 0.071
embryonic morphogenesis GO:0048598 85 0.071
positive regulation of developmental process GO:0051094 314 0.069
cell cycle phase transition GO:0044770 173 0.068
lipid biosynthetic process GO:0008610 177 0.067
positive regulation of nfat protein import into nucleus GO:0051533 3 0.066
epidermis development GO:0008544 59 0.065
multicellular organism reproduction GO:0032504 42 0.065
lipid metabolic process GO:0006629 381 0.062
myeloid cell differentiation GO:0030099 117 0.061
ion homeostasis GO:0050801 230 0.061
cation homeostasis GO:0055080 189 0.060
blood vessel development GO:0001568 172 0.059
positive regulation of cell differentiation GO:0045597 211 0.059
regulation of cell division GO:0051302 116 0.059
hemopoiesis GO:0030097 180 0.058
sexual reproduction GO:0019953 37 0.057
regulation of cytoplasmic transport GO:1903649 149 0.056
epidermal cell differentiation GO:0009913 45 0.055
cellular divalent inorganic cation homeostasis GO:0072503 128 0.054
genitalia development GO:0048806 10 0.053
Worm
heart development GO:0007507 95 0.053
regulation of viral genome replication GO:0045069 48 0.053
oocyte development GO:0048599 1 0.053
t cell activation GO:0042110 99 0.050
positive regulation of mrna processing GO:0050685 17 0.049
positive regulation of gliogenesis GO:0014015 4 0.049
regulation of protein import into nucleus GO:0042306 78 0.047
cellular macromolecule catabolic process GO:0044265 380 0.045
positive regulation of cell death GO:0010942 263 0.044
gamete generation GO:0007276 25 0.043
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.042
leukocyte differentiation GO:0002521 98 0.042
regulation of protein targeting GO:1903533 91 0.041
positive regulation of phosphorylation GO:0042327 394 0.041
cardiovascular system development GO:0072358 262 0.040
striated muscle contraction GO:0006941 52 0.040
regulation of intracellular transport GO:0032386 195 0.040
calcium ion transport GO:0006816 147 0.040
negative regulation of epidermis development GO:0045683 5 0.039
vasculature development GO:0001944 181 0.039
determination of adult lifespan GO:0008340 2 0.039
chemical homeostasis GO:0048878 306 0.038
rna 3 end processing GO:0031123 35 0.038
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.038
regulation of cell activation GO:0050865 125 0.038
negative regulation of cell cycle process GO:0010948 121 0.038
cellular chemical homeostasis GO:0055082 180 0.037
sequestering of metal ion GO:0051238 24 0.037
response to external biotic stimulus GO:0043207 261 0.037
regulation of mitotic cell cycle GO:0007346 189 0.036
generation of neurons GO:0048699 152 0.036
positive regulation of cytoplasmic transport GO:1903651 82 0.036
developmental process involved in reproduction GO:0003006 66 0.035
Worm
rna export from nucleus GO:0006405 33 0.034
regulation of mitotic cell cycle phase transition GO:1901990 118 0.034
spermatid development GO:0007286 4 0.034
regulation of small gtpase mediated signal transduction GO:0051056 156 0.034
regulation of cell maturation GO:1903429 3 0.033
positive regulation of synaptic transmission GO:0050806 4 0.033
metal ion homeostasis GO:0055065 169 0.033
histone demethylation GO:0016577 15 0.032
multicellular organismal aging GO:0010259 3 0.031
respiratory system development GO:0060541 22 0.030
skin development GO:0043588 76 0.030
nuclear transport GO:0051169 179 0.030
negative regulation of multicellular organismal process GO:0051241 317 0.030
alternative mrna splicing via spliceosome GO:0000380 27 0.029
Fly
response to wounding GO:0009611 168 0.029
regulation of cell differentiation GO:0045595 393 0.028
metal ion transport GO:0030001 272 0.028
germ cell development GO:0007281 8 0.028
regulation of protein transport GO:0051223 213 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
jnk cascade GO:0007254 80 0.028
apoptotic cell clearance GO:0043277 12 0.027
positive regulation of lymphocyte activation GO:0051251 73 0.027
t cell differentiation GO:0030217 29 0.027
cation transport GO:0006812 331 0.027
respiratory tube development GO:0030323 20 0.026
mitotic cell cycle phase transition GO:0044772 162 0.026
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
dna damage checkpoint GO:0000077 68 0.025
homeostasis of number of cells GO:0048872 40 0.025
stress activated protein kinase signaling cascade GO:0031098 94 0.025
engulfment of apoptotic cell GO:0043652 2 0.024
divalent inorganic cation transport GO:0072511 158 0.024
body morphogenesis GO:0010171 11 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.023
regulation of response to wounding GO:1903034 101 0.023
calcium ion homeostasis GO:0055074 122 0.023
locomotory behavior GO:0007626 1 0.023
regulation of dna templated transcription elongation GO:0032784 23 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
regulation of wound healing GO:0061041 56 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
blood vessel morphogenesis GO:0048514 162 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
erythrocyte development GO:0048821 3 0.022
epithelial cell proliferation GO:0050673 128 0.021
demethylation GO:0070988 37 0.021
myeloid cell homeostasis GO:0002262 34 0.021
formation of primary germ layer GO:0001704 42 0.021
regulation of keratinocyte proliferation GO:0010837 11 0.020
maintenance of location GO:0051235 112 0.020
regulation of ras protein signal transduction GO:0046578 155 0.020
protein dealkylation GO:0008214 17 0.020
regulation of epidermis development GO:0045682 19 0.019
positive regulation of intracellular transport GO:0032388 104 0.019
negative regulation of response to dna damage stimulus GO:2001021 33 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.019
keratinocyte differentiation GO:0030216 36 0.019
chromosome segregation GO:0007059 114 0.019
positive regulation of meiotic cell cycle GO:0051446 2 0.019
regulation of sequestering of calcium ion GO:0051282 41 0.019
regulation of gene expression epigenetic GO:0040029 73 0.018
nuclear mrna surveillance GO:0071028 4 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
negative regulation of viral genome replication GO:0045071 35 0.018
positive regulation of viral process GO:0048524 37 0.018
protein localization to nucleus GO:0034504 136 0.018
mrna 3 end processing GO:0031124 24 0.018
sequestering of calcium ion GO:0051208 17 0.018
nucleus localization GO:0051647 1 0.018
organophosphate catabolic process GO:0046434 430 0.017
response to biotic stimulus GO:0009607 276 0.017
rna localization GO:0006403 41 0.017
axon regeneration GO:0031103 1 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
spermatid differentiation GO:0048515 4 0.017
central nervous system development GO:0007417 123 0.017
regulation of anatomical structure size GO:0090066 101 0.017
dna templated transcription termination GO:0006353 3 0.016
regulation of intracellular protein transport GO:0033157 123 0.016
regulation of stress activated mapk cascade GO:0032872 84 0.016
positive regulation of protein localization to nucleus GO:1900182 48 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
pattern specification process GO:0007389 43 0.016
negative regulation of epithelial cell differentiation GO:0030857 6 0.016
macrophage activation GO:0042116 12 0.016
divalent inorganic cation homeostasis GO:0072507 136 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
erythrocyte differentiation GO:0030218 28 0.015
regulation of immune response GO:0050776 201 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
regulation of protein complex assembly GO:0043254 147 0.015
cell junction organization GO:0034330 79 0.015
positive regulation of protein transport GO:0051222 135 0.015
developmental growth GO:0048589 48 0.015
system process GO:0003008 349 0.014
somitogenesis GO:0001756 2 0.014
3 utr mediated mrna stabilization GO:0070935 8 0.014
spindle organization GO:0007051 53 0.014
Fly
negative regulation of defense response GO:0031348 47 0.013
protein targeting GO:0006605 187 0.013
response to virus GO:0009615 126 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
defense response to virus GO:0051607 71 0.013
response to oxidative stress GO:0006979 121 0.013
hormone metabolic process GO:0042445 61 0.012
protein complex disassembly GO:0043241 52 0.012
positive regulation of astrocyte differentiation GO:0048711 2 0.012
phagocytosis GO:0006909 42 0.012
ribonucleoprotein complex disassembly GO:0032988 7 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
positive regulation of protein import into nucleus GO:0042307 46 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.012
mitotic spindle organization GO:0007052 27 0.012
Fly
cytoplasmic transport GO:0016482 379 0.012
hindbrain development GO:0030902 3 0.012
regulation of homeostatic process GO:0032844 121 0.012
negative regulation of cell cycle GO:0045786 193 0.012
positive regulation of transport GO:0051050 336 0.012
response to organic cyclic compound GO:0014070 204 0.012
stress activated mapk cascade GO:0051403 93 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
blood circulation GO:0008015 113 0.012
positive regulation of transcription factor import into nucleus GO:0042993 25 0.011
regulation of viral process GO:0050792 103 0.011
digestive system development GO:0055123 75 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
regulation of leukocyte activation GO:0002694 115 0.011
signal transduction by p53 class mediator GO:0072331 72 0.011
response to other organism GO:0051707 261 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
negative regulation of immune system process GO:0002683 136 0.011
neuron differentiation GO:0030182 138 0.011
positive regulation of organelle organization GO:0010638 195 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
protein autophosphorylation GO:0046777 123 0.011
regulation of multi organism process GO:0043900 157 0.011
macromolecular complex disassembly GO:0032984 60 0.011
regulation of protein localization to nucleus GO:1900180 85 0.011
negative regulation of stress activated mapk cascade GO:0032873 19 0.010
renal system development GO:0072001 63 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
regulation of cell growth GO:0001558 135 0.010
ribonucleoside catabolic process GO:0042454 406 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
circadian regulation of translation GO:0097167 1 0.010
nucleoside triphosphate catabolic process GO:0009143 394 0.010

U2AF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.192
eye and adnexa disease DOID:1492 150 0.192
nervous system disease DOID:863 431 0.192
retinal disease DOID:5679 118 0.184
retinal degeneration DOID:8466 89 0.184
eye disease DOID:5614 149 0.184
disease of cellular proliferation DOID:14566 174 0.040
central nervous system disease DOID:331 186 0.025
cancer DOID:162 167 0.016
organ system cancer DOID:0050686 164 0.015
neurodegenerative disease DOID:1289 102 0.012
retinitis pigmentosa DOID:10584 51 0.011
musculoskeletal system disease DOID:17 223 0.010