Homo sapiens

113 known processes

IL27

interleukin 27

(Aliases: IL-27,MGC71873,IL30,IL-27A,p28,IL27p28)

IL27 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 41 0.086
cellular amino acid metabolic process GO:0006520 116 0.083
regulation of cellular amine metabolic process GO:0033238 11 0.073
regulation of cellular amino acid metabolic process GO:0006521 6 0.072
regulation of cellular ketone metabolic process GO:0010565 50 0.067
amine metabolic process GO:0009308 44 0.067
positive regulation of cellular amine metabolic process GO:0033240 7 0.058
cellular ketone metabolic process GO:0042180 80 0.057
post embryonic development GO:0009791 2 0.055
transmembrane transport GO:0055085 399 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
secretion GO:0046903 254 0.045
cation transmembrane transport GO:0098655 238 0.044
multicellular organismal aging GO:0010259 3 0.042
ion transmembrane transport GO:0034220 338 0.040
determination of adult lifespan GO:0008340 2 0.040
quorum sensing GO:0009372 1 0.038
immune response GO:0006955 307 0.037
defense response GO:0006952 315 0.037
cation transport GO:0006812 331 0.036
system process GO:0003008 349 0.034
positive regulation of phosphorylation GO:0042327 394 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
ion homeostasis GO:0050801 230 0.033
locomotory behavior GO:0007626 1 0.032
chemical homeostasis GO:0048878 306 0.032
positive regulation of transport GO:0051050 336 0.032
female gamete generation GO:0007292 2 0.032
cellular homeostasis GO:0019725 196 0.031
cytoplasmic transport GO:0016482 379 0.031
regulation of protein transport GO:0051223 213 0.031
regulation of immune response GO:0050776 201 0.031
regulation of protein localization GO:0032880 296 0.031
oogenesis GO:0048477 2 0.031
ras protein signal transduction GO:0007265 73 0.029
single organism cellular localization GO:1902580 332 0.029
regulation of hormone levels GO:0010817 125 0.029
somatostatin receptor signaling pathway GO:0038169 1 0.028
short chain fatty acid import GO:0015913 1 0.027
secretion by cell GO:0032940 226 0.027
innate immune response GO:0045087 178 0.027
lipid metabolic process GO:0006629 381 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.027
regulation of secretion GO:0051046 194 0.026
inorganic ion transmembrane transport GO:0098660 231 0.026
neuromuscular junction development GO:0007528 3 0.025
alpha ketoglutarate transport GO:0015742 1 0.025
regeneration GO:0031099 4 0.025
negative regulation of protein metabolic process GO:0051248 391 0.025
protein localization to organelle GO:0033365 280 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
single organism membrane organization GO:0044802 268 0.024
negative regulation of wnt protein secretion GO:0061358 1 0.024
response to abiotic stimulus GO:0009628 336 0.024
regulation of transferase activity GO:0051338 355 0.024
cellular lipid metabolic process GO:0044255 303 0.024
nitrogen compound transport GO:0071705 191 0.024
cell adhesion GO:0007155 325 0.024
inorganic cation transmembrane transport GO:0098662 194 0.024
regulation of secretion by cell GO:1903530 177 0.024
positive regulation of immune system process GO:0002684 283 0.023
response to external biotic stimulus GO:0043207 261 0.023
rho protein signal transduction GO:0007266 26 0.023
cation homeostasis GO:0055080 189 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
regulation of cell cycle process GO:0010564 266 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
positive regulation of hydrolase activity GO:0051345 331 0.022
membrane organization GO:0061024 292 0.022
regulation of kinase activity GO:0043549 314 0.022
sodium independent organic anion transport GO:0043252 2 0.022
response to other organism GO:0051707 261 0.022
negative regulation of cell death GO:0060548 345 0.022
metal ion transport GO:0030001 272 0.022
dephosphorylation GO:0016311 209 0.022
regulation of cell cycle GO:0051726 393 0.022
regulation of protein kinase activity GO:0045859 289 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
monovalent inorganic cation transport GO:0015672 128 0.022
homeostasis of number of cells in a free living population GO:0048874 1 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
reactive nitrogen species metabolic process GO:2001057 3 0.021
response to biotic stimulus GO:0009607 276 0.021
somatostatin signaling pathway GO:0038170 1 0.021
urate transport GO:0015747 3 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
segmentation GO:0035282 4 0.021
opioid receptor signaling pathway GO:0038003 4 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
rhythmic behavior GO:0007622 2 0.021
vesicle mediated transport GO:0016192 371 0.021
biological adhesion GO:0022610 331 0.020
response to oxygen containing compound GO:1901700 369 0.020
intracellular protein transport GO:0006886 270 0.020
protein targeting GO:0006605 187 0.020
cellular cation homeostasis GO:0030003 163 0.020
negative regulation of transport GO:0051051 176 0.020
protein catabolic process GO:0030163 325 0.020
positive regulation of secretion by cell GO:1903532 108 0.020
cytokine production GO:0001816 247 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
divalent inorganic cation homeostasis GO:0072507 136 0.020
positive regulation of intestinal epithelial structure maintenance GO:0060731 1 0.019
regulation of cellular response to stress GO:0080135 244 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
purine containing compound catabolic process GO:0072523 411 0.019
positive regulation of transferase activity GO:0051347 227 0.019
apoptotic signaling pathway GO:0097190 268 0.019
nicotinate transport GO:2001142 1 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
regulation of transporter activity GO:0032409 82 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
glycosyl compound catabolic process GO:1901658 413 0.018
protein secretion GO:0009306 98 0.018
cellular potassium ion transport GO:0071804 60 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
cellular protein catabolic process GO:0044257 261 0.018
interspecies quorum sensing GO:0052097 1 0.018
positive regulation of large conductance calcium activated potassium channel activity GO:1902608 2 0.018
regulation of transmembrane transporter activity GO:0022898 74 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
positive regulation of kinase activity GO:0033674 204 0.018
cellular metal ion homeostasis GO:0006875 146 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
mitotic cell cycle GO:0000278 326 0.018
organophosphate catabolic process GO:0046434 430 0.018
circadian behavior GO:0048512 2 0.018
adult locomotory behavior GO:0008344 1 0.018
multi organism cellular process GO:0044764 156 0.018
cellular chemical homeostasis GO:0055082 180 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.017
potassium ion transport GO:0006813 62 0.017
positive regulation of catabolic process GO:0009896 310 0.017
purine ribonucleotide catabolic process GO:0009154 404 0.017
nucleotide catabolic process GO:0009166 408 0.017
organic hydroxy compound transport GO:0015850 63 0.017
regulation of proteolysis GO:0030162 293 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
actin filament based process GO:0030029 224 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
response to virus GO:0009615 126 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
anion transport GO:0006820 161 0.017
positive regulation of glucocorticoid secretion GO:2000851 4 0.017
cellular response to oxygen containing compound GO:1901701 276 0.016
nervous system development GO:0007399 293 0.016
cellular ion homeostasis GO:0006873 168 0.016
nuclear transport GO:0051169 179 0.016
spermatid differentiation GO:0048515 4 0.016
immune effector process GO:0002252 159 0.016
memory GO:0007613 3 0.016
positive regulation of cell death GO:0010942 263 0.016
cell activation GO:0001775 213 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
regulation of metal ion transport GO:0010959 120 0.016
positive regulation of secretion GO:0051047 116 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
regulation of ion transport GO:0043269 189 0.016
regulation of response to external stimulus GO:0032101 222 0.016
mapk cascade GO:0000165 288 0.016
carnitine transmembrane transport GO:1902603 3 0.016
regulation of protein secretion GO:0050708 86 0.016
protein oligomerization GO:0051259 173 0.016
mitotic cell cycle process GO:1903047 286 0.016
anterior posterior axis specification GO:0009948 2 0.016
visual behavior GO:0007632 2 0.016
oocyte development GO:0048599 1 0.016
interspecies interaction between organisms GO:0044419 156 0.016
regulation of ion transmembrane transport GO:0034765 132 0.016
lipid transport GO:0006869 90 0.016
sodium dependent organic cation transport GO:0070715 1 0.016
regulation of cell migration GO:0030334 289 0.016
metal ion homeostasis GO:0055065 169 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
positive regulation of immune response GO:0050778 159 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
regulation of cell differentiation GO:0045595 393 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
response to lipid GO:0033993 206 0.015
protein ubiquitination GO:0016567 314 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
renal tubular secretion GO:0097254 1 0.015
oocyte differentiation GO:0009994 2 0.015
regulation of ion transmembrane transporter activity GO:0032412 72 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
associative learning GO:0008306 1 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
negative regulation of protein modification process GO:0031400 200 0.015
compound eye development GO:0048749 1 0.015
regulation of cytokine production GO:0001817 232 0.015
positive regulation of cytokine production GO:0001819 167 0.015
blastoderm segmentation GO:0007350 2 0.015
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.015
protein maturation GO:0051604 233 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
regulation of intracellular transport GO:0032386 195 0.015
protein localization to nucleus GO:0034504 136 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.014
regulation of mapk cascade GO:0043408 262 0.014
peptidyl serine modification GO:0018209 106 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
protein localization to membrane GO:0072657 160 0.014
maintenance of location GO:0051235 112 0.014
endomembrane system organization GO:0010256 196 0.014
organic anion transport GO:0015711 103 0.014
response to nitrogen compound GO:1901698 184 0.014
lipid localization GO:0010876 106 0.014
regulation of cellular component movement GO:0051270 334 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
regulation of transmembrane transport GO:0034762 139 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
microtubule based process GO:0007017 210 0.014
potassium ion transmembrane transport GO:0071805 60 0.014
peptidyl tyrosine modification GO:0018212 170 0.014
behavioral response to ethanol GO:0048149 2 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
peptidyl serine phosphorylation GO:0018105 101 0.014
cellular calcium ion homeostasis GO:0006874 117 0.014
spermatid development GO:0007286 4 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
regulation of membrane potential GO:0042391 95 0.014
cellular response to toxic substance GO:0097237 4 0.014
metencephalon development GO:0022037 2 0.014
activation of immune response GO:0002253 114 0.014
negative regulation of developmental process GO:0051093 247 0.014
positive regulation of developmental process GO:0051094 314 0.014
nucleoside catabolic process GO:0009164 408 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
regulation of protein complex assembly GO:0043254 147 0.014
blood vessel morphogenesis GO:0048514 162 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
tripartite regional subdivision GO:0007351 2 0.014
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 1 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
quorum sensing involved in interaction with host GO:0052106 1 0.013
leukocyte activation GO:0045321 164 0.013
wnt signaling pathway GO:0016055 156 0.013
glycoprotein metabolic process GO:0009100 110 0.013
neuroblast proliferation GO:0007405 4 0.013
protein processing GO:0016485 226 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
response to radiation GO:0009314 151 0.013
response to growth factor GO:0070848 205 0.013
positive regulation of protein transport GO:0051222 135 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.013
cellular response to lipid GO:0071396 127 0.013
protein import GO:0017038 130 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
response to fungus GO:0009620 4 0.013
hindbrain development GO:0030902 3 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
growth GO:0040007 202 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
negative regulation of cytokine production GO:0001818 82 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
cell projection organization GO:0030030 252 0.012
regulation of protein catabolic process GO:0042176 155 0.012
anatomical structure homeostasis GO:0060249 100 0.012
defense response to other organism GO:0098542 129 0.012
tissue regeneration GO:0042246 3 0.012
hormone transport GO:0009914 68 0.012
regulation of locomotion GO:0040012 329 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
cell cell signaling GO:0007267 155 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
carbohydrate metabolic process GO:0005975 207 0.012
cellular protein complex assembly GO:0043623 188 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
atp metabolic process GO:0046034 176 0.012
cell division GO:0051301 168 0.012
regulation of leukocyte activation GO:0002694 115 0.012
negative regulation of secretion by cell GO:1903531 52 0.012
epithelium development GO:0060429 227 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
hair follicle morphogenesis GO:0031069 2 0.012
epidermis morphogenesis GO:0048730 3 0.012
organelle assembly GO:0070925 176 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.012
lipid biosynthetic process GO:0008610 177 0.012
single organism nuclear import GO:1902593 104 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
short chain fatty acid transport GO:0015912 1 0.012
actin cytoskeleton organization GO:0030036 207 0.012
sensory perception GO:0007600 103 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
divalent inorganic cation transport GO:0072511 158 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
response to cytokine GO:0034097 232 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
alpha amino acid metabolic process GO:1901605 72 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
visual learning GO:0008542 1 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
dna repair GO:0006281 198 0.011
positive regulation of organelle organization GO:0010638 195 0.011
regulation of growth GO:0040008 165 0.011
regulation of defense response GO:0031347 154 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
chromatin organization GO:0006325 351 0.011
mating GO:0007618 1 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
sequestering of metal ion GO:0051238 24 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
neurogenesis GO:0022008 169 0.011
rna processing GO:0006396 255 0.011
single organism cell adhesion GO:0098602 179 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
negative regulation of protein transport GO:0051224 75 0.011
meiotic chromosome segregation GO:0045132 4 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
negative regulation of secretion GO:0051048 58 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of homeostatic process GO:0032844 121 0.011
negative regulation of transferase activity GO:0051348 124 0.011
nuclear import GO:0051170 106 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
cell growth GO:0016049 160 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
defense response to virus GO:0051607 71 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
cell fate determination GO:0001709 3 0.011
actin filament based movement GO:0030048 17 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
protein import into nucleus GO:0006606 104 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
regulation of meiosis GO:0040020 3 0.011
positive regulation of proteolysis GO:0045862 142 0.011
divalent metal ion transport GO:0070838 152 0.011
response to bacterium GO:0009617 144 0.011
regulation of multi organism process GO:0043900 157 0.011
cofactor metabolic process GO:0051186 87 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
calcium ion homeostasis GO:0055074 122 0.011
single organismal cell cell adhesion GO:0016337 148 0.011
neurological system process GO:0050877 163 0.011
organic acid biosynthetic process GO:0016053 97 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
fatty acid metabolic process GO:0006631 115 0.011
protein targeting to nucleus GO:0044744 104 0.011
cell cycle phase transition GO:0044770 173 0.011
taxis GO:0042330 157 0.011
regulation of innate immune response GO:0045088 97 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
regulation of cell growth GO:0001558 135 0.011
response to organic cyclic compound GO:0014070 204 0.011
regulation of cell activation GO:0050865 125 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
peripheral nervous system development GO:0007422 2 0.011
spinal cord development GO:0021510 4 0.011
regulation of dephosphorylation GO:0035303 96 0.011
response to wounding GO:0009611 168 0.011
response to decreased oxygen levels GO:0036293 96 0.011
cytosolic calcium ion homeostasis GO:0051480 89 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.010
positive regulation of digestive system process GO:0060456 2 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
epithelium migration GO:0090132 119 0.010
regulation of glucocorticoid secretion GO:2000849 4 0.010
positive regulation of cell motility GO:2000147 177 0.010
protein autophosphorylation GO:0046777 123 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
negative regulation of reactive oxygen species biosynthetic process GO:1903427 1 0.010
viral process GO:0016032 146 0.010
cell projection assembly GO:0030031 126 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010
oxidation reduction process GO:0055114 396 0.010
regulation of cell motility GO:2000145 299 0.010
small molecule catabolic process GO:0044282 92 0.010
mitochondrion organization GO:0007005 156 0.010
cell development GO:0048468 328 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
negative regulation of locomotion GO:0040013 118 0.010
cell morphogenesis GO:0000902 296 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
meiosis i GO:0007127 4 0.010
small molecule biosynthetic process GO:0044283 157 0.010

IL27 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.030
sensory system disease DOID:0050155 203 0.024
nervous system disease DOID:863 431 0.024
eye and adnexa disease DOID:1492 150 0.020
eye disease DOID:5614 149 0.020
acquired metabolic disease DOID:0060158 58 0.020
retinal disease DOID:5679 118 0.017
inherited metabolic disorder DOID:655 242 0.016
musculoskeletal system disease DOID:17 223 0.015
central nervous system disease DOID:331 186 0.015
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
retinal degeneration DOID:8466 89 0.013
organ system cancer DOID:0050686 164 0.012
immune system disease DOID:2914 155 0.012
cardiovascular system disease DOID:1287 106 0.011
carbohydrate metabolic disorder DOID:2978 55 0.011
heart disease DOID:114 68 0.011
connective tissue disease DOID:65 109 0.010