Homo sapiens

19 known processes

KIF2A

kinesin heavy chain member 2A

(Aliases: HK2,KIF2)

KIF2A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 44 0.219
protein modification by small protein conjugation GO:0032446 342 0.217
female gamete generation GO:0007292 2 0.207
positive regulation of cellular component organization GO:0051130 376 0.184
organelle fission GO:0048285 149 0.180
Worm Fly
cellular amine metabolic process GO:0044106 41 0.178
cellular component morphogenesis GO:0032989 314 0.173
regulation of cellular amine metabolic process GO:0033238 11 0.165
protein ubiquitination GO:0016567 314 0.155
negative regulation of protein metabolic process GO:0051248 391 0.152
ras protein signal transduction GO:0007265 73 0.145
nervous system development GO:0007399 293 0.140
negative regulation of cellular protein metabolic process GO:0032269 353 0.132
oogenesis GO:0048477 2 0.124
small gtpase mediated signal transduction GO:0007264 78 0.120
post embryonic development GO:0009791 2 0.118
mitotic cell cycle process GO:1903047 286 0.116
vesicle mediated transport GO:0016192 371 0.111
microtubule cytoskeleton organization GO:0000226 176 0.107
cell development GO:0048468 328 0.099
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.098
embryo development GO:0009790 123 0.093
Worm
positive regulation of cell proliferation GO:0008284 301 0.090
microtubule based process GO:0007017 210 0.088
regulation of cell morphogenesis GO:0022604 153 0.086
regulation of cellular amino acid metabolic process GO:0006521 6 0.085
cell cycle phase transition GO:0044770 173 0.084
nucleoside catabolic process GO:0009164 408 0.082
protein catabolic process GO:0030163 325 0.078
negative regulation of apoptotic process GO:0043066 316 0.077
purine ribonucleotide catabolic process GO:0009154 404 0.077
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.077
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.075
modification dependent protein catabolic process GO:0019941 209 0.074
regulation of anatomical structure morphogenesis GO:0022603 286 0.071
positive regulation of transferase activity GO:0051347 227 0.070
morphogenesis of embryonic epithelium GO:0016331 4 0.070
positive regulation of protein phosphorylation GO:0001934 313 0.069
vasculature development GO:0001944 181 0.068
regulation of cell differentiation GO:0045595 393 0.068
ribonucleoside catabolic process GO:0042454 406 0.068
oocyte differentiation GO:0009994 2 0.068
regulation of cell cycle GO:0051726 393 0.065
negative regulation of cell cycle GO:0045786 193 0.064
intracellular protein transport GO:0006886 270 0.063
tube development GO:0035295 125 0.062
protein targeting to nucleus GO:0044744 104 0.062
cell projection organization GO:0030030 252 0.062
cellular amino acid metabolic process GO:0006520 116 0.062
cellular protein catabolic process GO:0044257 261 0.062
regulation of protein catabolic process GO:0042176 155 0.061
regulation of cytoskeleton organization GO:0051493 177 0.061
negative regulation of cellular component organization GO:0051129 235 0.061
lipid metabolic process GO:0006629 381 0.060
neuron projection development GO:0031175 106 0.059
cellular response to dna damage stimulus GO:0006974 379 0.058
histone modification GO:0016570 251 0.058
regulation of response to dna damage stimulus GO:2001020 94 0.057
purine ribonucleoside metabolic process GO:0046128 437 0.057
covalent chromatin modification GO:0016569 254 0.056
chromatin modification GO:0016568 298 0.055
regulation of chromatin modification GO:1903308 51 0.054
neuron differentiation GO:0030182 138 0.054
regulation of protein kinase activity GO:0045859 289 0.054
regulation of protein transport GO:0051223 213 0.053
positive regulation of phosphorylation GO:0042327 394 0.053
regulation of transferase activity GO:0051338 355 0.052
protein processing GO:0016485 226 0.052
cellular ketone metabolic process GO:0042180 80 0.052
nucleoside triphosphate catabolic process GO:0009143 394 0.051
negative regulation of organelle organization GO:0010639 126 0.051
mitotic cell cycle GO:0000278 326 0.051
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.051
ubiquitin dependent protein catabolic process GO:0006511 206 0.051
blood vessel development GO:0001568 172 0.051
protein localization to organelle GO:0033365 280 0.051
positive regulation of cellular amine metabolic process GO:0033240 7 0.050
system process GO:0003008 349 0.050
cellular lipid metabolic process GO:0044255 303 0.049
regulation of cell development GO:0060284 161 0.049
cell part morphogenesis GO:0032990 137 0.048
neuron development GO:0048666 113 0.048
oocyte development GO:0048599 1 0.048
purine nucleoside catabolic process GO:0006152 398 0.048
modification dependent macromolecule catabolic process GO:0043632 212 0.047
regulation of mitotic cell cycle GO:0007346 189 0.047
regulation of growth GO:0040008 165 0.046
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.045
organophosphate biosynthetic process GO:0090407 163 0.045
embryonic epithelial tube formation GO:0001838 4 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
response to abiotic stimulus GO:0009628 336 0.045
locomotory behavior GO:0007626 1 0.044
dephosphorylation GO:0016311 209 0.044
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.044
glycosyl compound catabolic process GO:1901658 413 0.044
negative regulation of protein maturation GO:1903318 142 0.044
ribonucleotide catabolic process GO:0009261 405 0.043
regulation of cellular response to stress GO:0080135 244 0.043
signal transduction by phosphorylation GO:0023014 297 0.043
regulation of cellular component biogenesis GO:0044087 281 0.043
regulation of kinase activity GO:0043549 314 0.043
regulation of chromosome organization GO:0033044 103 0.042
cell morphogenesis GO:0000902 296 0.042
centrosome organization GO:0051297 58 0.042
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
positive regulation of protein kinase activity GO:0045860 190 0.042
negative regulation of protein processing GO:0010955 142 0.041
cellular macromolecule catabolic process GO:0044265 380 0.041
lung alveolus development GO:0048286 4 0.040
regulation of intracellular transport GO:0032386 195 0.040
negative regulation of protein modification process GO:0031400 200 0.040
cellular macromolecular complex assembly GO:0034622 324 0.040
Worm
blood vessel morphogenesis GO:0048514 162 0.039
regulation of dna metabolic process GO:0051052 153 0.039
neurogenesis GO:0022008 169 0.039
regulation of proteasomal protein catabolic process GO:0061136 87 0.039
posttranscriptional regulation of gene expression GO:0010608 213 0.039
purine containing compound catabolic process GO:0072523 411 0.037
regulation of cell cycle process GO:0010564 266 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.037
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.037
single organism cellular localization GO:1902580 332 0.037
Fly
protein maturation GO:0051604 233 0.036
regulation of protein localization GO:0032880 296 0.036
purine ribonucleoside catabolic process GO:0046130 398 0.035
regulation of protein processing GO:0070613 150 0.035
protein import into nucleus GO:0006606 104 0.035
positive regulation of cellular component biogenesis GO:0044089 158 0.035
negative regulation of cell death GO:0060548 345 0.035
chromatin organization GO:0006325 351 0.035
chromosome segregation GO:0007059 114 0.034
Human Worm Fly
single organism carbohydrate metabolic process GO:0044723 193 0.034
cytoplasmic transport GO:0016482 379 0.034
purine nucleotide catabolic process GO:0006195 405 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
single organism nuclear import GO:1902593 104 0.034
regulation of chromatin organization GO:1902275 56 0.033
proteasomal protein catabolic process GO:0010498 176 0.033
nitrogen compound transport GO:0071705 191 0.033
protein localization to nucleus GO:0034504 136 0.033
neural tube formation GO:0001841 3 0.033
regulation of protein maturation GO:1903317 150 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.032
organophosphate catabolic process GO:0046434 430 0.032
intrinsic apoptotic signaling pathway GO:0097193 127 0.032
secretion GO:0046903 254 0.032
positive regulation of organelle organization GO:0010638 195 0.032
dna conformation change GO:0071103 113 0.031
regulation of proteolysis GO:0030162 293 0.031
regulation of mitotic cell cycle phase transition GO:1901990 118 0.031
generation of neurons GO:0048699 152 0.030
inorganic ion transmembrane transport GO:0098660 231 0.030
protein import GO:0017038 130 0.030
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.030
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.030
peptidyl serine modification GO:0018209 106 0.030
cell adhesion GO:0007155 325 0.030
regulation of nucleocytoplasmic transport GO:0046822 98 0.029
nucleoside triphosphate metabolic process GO:0009141 422 0.029
positive regulation of developmental process GO:0051094 314 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
regulation of cell projection organization GO:0031344 107 0.029
negative regulation of programmed cell death GO:0043069 321 0.029
positive regulation of transport GO:0051050 336 0.029
establishment of protein localization to organelle GO:0072594 172 0.029
cell growth GO:0016049 160 0.029
nucleocytoplasmic transport GO:0006913 176 0.029
positive regulation of cell differentiation GO:0045597 211 0.029
spermatid development GO:0007286 4 0.029
guanosine containing compound metabolic process GO:1901068 244 0.028
actin filament based process GO:0030029 224 0.028
nuclear import GO:0051170 106 0.028
negative regulation of chromosome organization GO:2001251 48 0.028
organonitrogen compound biosynthetic process GO:1901566 200 0.028
negative regulation of proteolysis GO:0045861 132 0.027
innate immune response GO:0045087 178 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
regulation of cellular protein catabolic process GO:1903362 96 0.027
positive regulation of kinase activity GO:0033674 204 0.027
organelle localization GO:0051640 84 0.027
Fly
response to ionizing radiation GO:0010212 65 0.027
peptidyl serine phosphorylation GO:0018105 101 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
nucleotide catabolic process GO:0009166 408 0.026
immune response GO:0006955 307 0.026
mapk cascade GO:0000165 288 0.026
response to radiation GO:0009314 151 0.026
regulation of small gtpase mediated signal transduction GO:0051056 156 0.026
nuclear transport GO:0051169 179 0.026
regulation of microtubule based process GO:0032886 74 0.025
negative regulation of cell differentiation GO:0045596 171 0.025
positive regulation of protein transport GO:0051222 135 0.025
double strand break repair GO:0006302 101 0.025
multicellular organismal aging GO:0010259 3 0.025
defense response GO:0006952 315 0.025
protein polymerization GO:0051258 71 0.025
Worm
positive regulation of catabolic process GO:0009896 310 0.024
single organism reproductive process GO:0044702 98 0.024
negative regulation of cell cycle process GO:0010948 121 0.024
cellular protein complex assembly GO:0043623 188 0.024
Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.024
cation transmembrane transport GO:0098655 238 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.024
chordate embryonic development GO:0043009 34 0.024
purine nucleotide biosynthetic process GO:0006164 84 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
rho protein signal transduction GO:0007266 26 0.023
response to other organism GO:0051707 261 0.023
dna packaging GO:0006323 77 0.023
endocytosis GO:0006897 159 0.023
nuclear division GO:0000280 128 0.022
Worm Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
regulation of establishment of protein localization GO:0070201 242 0.022
cell projection morphogenesis GO:0048858 129 0.022
positive regulation of cell death GO:0010942 263 0.022
dna replication GO:0006260 116 0.022
growth GO:0040007 202 0.022
positive regulation of dendrite morphogenesis GO:0050775 3 0.022
nucleoside monophosphate metabolic process GO:0009123 191 0.022
negative regulation of protein phosphorylation GO:0001933 140 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
neurological system process GO:0050877 163 0.021
blastocyst development GO:0001824 3 0.021
epithelium development GO:0060429 227 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.021
meiosis i GO:0007127 4 0.020
Fly
protein targeting GO:0006605 187 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
sister chromatid segregation GO:0000819 54 0.020
Fly
gtp metabolic process GO:0046039 239 0.020
lung saccule development GO:0060430 2 0.020
apoptotic signaling pathway GO:0097190 268 0.020
anterior posterior axis specification GO:0009948 2 0.020
response to biotic stimulus GO:0009607 276 0.020
negative regulation of developmental process GO:0051093 247 0.019
regulation of neuron projection development GO:0010975 57 0.019
ion transmembrane transport GO:0034220 338 0.019
reproductive process GO:0022414 106 0.019
nucleoside phosphate biosynthetic process GO:1901293 109 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
rna processing GO:0006396 255 0.019
dna repair GO:0006281 198 0.019
mrna metabolic process GO:0016071 175 0.019
response to external biotic stimulus GO:0043207 261 0.019
regulation of protein targeting GO:1903533 91 0.019
negative regulation of catabolic process GO:0009895 104 0.018
endomembrane system organization GO:0010256 196 0.018
chromatin assembly or disassembly GO:0006333 78 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
cell cell signaling GO:0007267 155 0.018
cell activation GO:0001775 213 0.018
positive regulation of cell projection organization GO:0031346 64 0.018
transmembrane transport GO:0055085 399 0.018
organelle assembly GO:0070925 176 0.017
Fly
tube morphogenesis GO:0035239 95 0.017
regulation of histone modification GO:0031056 47 0.017
rna interference GO:0016246 4 0.017
purine containing compound biosynthetic process GO:0072522 88 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
cellular response to abiotic stimulus GO:0071214 117 0.017
biological adhesion GO:0022610 331 0.017
cell cycle g2 m phase transition GO:0044839 43 0.017
rna localization GO:0006403 41 0.017
mitotic nuclear division GO:0007067 119 0.016
Worm Fly
neuron death GO:0070997 65 0.016
regulation of neuron death GO:1901214 56 0.016
regulation of nuclear division GO:0051783 65 0.016
protein autophosphorylation GO:0046777 123 0.016
regulation of protein ubiquitination GO:0031396 95 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
behavior GO:0007610 112 0.016
regulation of ras gtpase activity GO:0032318 128 0.016
positive regulation of intracellular protein transport GO:0090316 76 0.015
regulation of protein complex assembly GO:0043254 147 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
microtubule organizing center organization GO:0031023 62 0.015
Fly
multicellular organismal signaling GO:0035637 34 0.015
regulation of cell growth GO:0001558 135 0.015
regulation of dna repair GO:0006282 47 0.015
intracellular mrna localization GO:0008298 1 0.015
regulation of protein localization to nucleus GO:1900180 85 0.015
regulation of microtubule cytoskeleton organization GO:0070507 61 0.015
negative regulation of kinase activity GO:0033673 106 0.015
rna 3 end processing GO:0031123 35 0.014
regulation of mapk cascade GO:0043408 262 0.014
centrosome cycle GO:0007098 32 0.014
Fly
neuromuscular junction development GO:0007528 3 0.014
segmentation GO:0035282 4 0.014
axon development GO:0061564 34 0.014
establishment of organelle localization GO:0051656 59 0.014
Fly
jak stat cascade GO:0007259 46 0.014
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.014
positive regulation of dna metabolic process GO:0051054 73 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.014
internal peptidyl lysine acetylation GO:0018393 97 0.014
cardiovascular system development GO:0072358 262 0.014
spermatid differentiation GO:0048515 4 0.014
ribonucleoprotein complex subunit organization GO:0071826 81 0.014
circulatory system development GO:0072359 262 0.014
cell cycle checkpoint GO:0000075 117 0.014
carbohydrate metabolic process GO:0005975 207 0.014
single organism membrane organization GO:0044802 268 0.014
negative regulation of protein catabolic process GO:0042177 59 0.014
positive regulation of cell cycle GO:0045787 140 0.013
rna transport GO:0050658 39 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
regulation of membrane potential GO:0042391 95 0.013
determination of adult lifespan GO:0008340 2 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
regulation of body fluid levels GO:0050878 99 0.013
mitotic sister chromatid segregation GO:0000070 53 0.013
Fly
gtp catabolic process GO:0006184 237 0.013
golgi vesicle transport GO:0048193 80 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
g1 s transition of mitotic cell cycle GO:0000082 78 0.013
chromatin remodeling GO:0006338 55 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
response to inorganic substance GO:0010035 127 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
cell cycle arrest GO:0007050 71 0.012
actin filament based movement GO:0030048 17 0.012
regulation of actin filament based process GO:0032970 141 0.012
positive regulation of protein complex assembly GO:0031334 86 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
regulation of cellular component movement GO:0051270 334 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
Worm
secretion by cell GO:0032940 226 0.012
endosomal transport GO:0016197 129 0.012
positive regulation of ras gtpase activity GO:0032320 117 0.012
developmental process involved in reproduction GO:0003006 66 0.012
positive regulation of growth GO:0045927 58 0.012
actin cytoskeleton organization GO:0030036 207 0.012
cell type specific apoptotic process GO:0097285 125 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
positive regulation of nervous system development GO:0051962 54 0.012
actin mediated cell contraction GO:0070252 12 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
regeneration GO:0031099 4 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.012
response to cytokine GO:0034097 232 0.012
sex differentiation GO:0007548 45 0.012
response to nitrogen compound GO:1901698 184 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
membrane organization GO:0061024 292 0.011
associative learning GO:0008306 1 0.011
positive regulation of cell development GO:0010720 92 0.011
regulation of neurogenesis GO:0050767 82 0.011
neuron projection morphogenesis GO:0048812 50 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
histone ubiquitination GO:0016574 31 0.011
negative regulation of cellular protein catabolic process GO:1903363 38 0.011
spindle organization GO:0007051 53 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.011
negative regulation of transferase activity GO:0051348 124 0.011
positive regulation of dendritic spine development GO:0060999 2 0.011
chemotaxis GO:0006935 157 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
receptor mediated endocytosis GO:0006898 84 0.011
regulation of cell motility GO:2000145 299 0.011
mrna processing GO:0006397 133 0.011
mrna transport GO:0051028 30 0.011
positive regulation of neuron differentiation GO:0045666 40 0.011
negative regulation of growth GO:0045926 97 0.011
protein polyubiquitination GO:0000209 110 0.011
positive regulation of secretion GO:0051047 116 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
cation transport GO:0006812 331 0.011
regulation of translation GO:0006417 89 0.011
glycerolipid metabolic process GO:0046486 107 0.011
cell junction organization GO:0034330 79 0.011
negative regulation of neuron apoptotic process GO:0043524 23 0.010
stem cell division GO:0017145 2 0.010
g2 m transition of mitotic cell cycle GO:0000086 41 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
dendrite development GO:0016358 24 0.010
regulation of neuron differentiation GO:0045664 70 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
regulation of dna replication GO:0006275 68 0.010
ribonucleotide biosynthetic process GO:0009260 81 0.010
chemical homeostasis GO:0048878 306 0.010
regulation of map kinase activity GO:0043405 108 0.010
positive regulation of cytoskeleton organization GO:0051495 83 0.010
cell division GO:0051301 168 0.010
Worm
mitotic cell cycle checkpoint GO:0007093 68 0.010
phospholipid metabolic process GO:0006644 99 0.010
internal protein amino acid acetylation GO:0006475 101 0.010
response to wounding GO:0009611 168 0.010

KIF2A disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.045
nervous system disease DOID:863 431 0.045