Homo sapiens

114 known processes

ATP6AP2

ATPase, H+ transporting, lysosomal accessory protein 2

(Aliases: ELDF10,MSTP009,ATP6IP2,MGC99577,M8-9,APT6M8-9,MRXE,XMRE,ATP6M8-9)

ATP6AP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phospholipid translocation GO:0045332 2 0.281
metal ion homeostasis GO:0055065 169 0.208
cellular homeostasis GO:0019725 196 0.182
membrane organization GO:0061024 292 0.169
post embryonic development GO:0009791 2 0.146
Worm Fly
cellular ion homeostasis GO:0006873 168 0.119
cellular metal ion homeostasis GO:0006875 146 0.111
negative regulation of glycoprotein metabolic process GO:1903019 8 0.109
cation homeostasis GO:0055080 189 0.107
regulation of glycoprotein metabolic process GO:1903018 19 0.103
ion transmembrane transport GO:0034220 338 0.100
drug transmembrane transport GO:0006855 7 0.098
purine nucleoside triphosphate metabolic process GO:0009144 412 0.095
cellular chemical homeostasis GO:0055082 180 0.091
cellular cation homeostasis GO:0030003 163 0.089
secretion GO:0046903 254 0.088
glycoprotein metabolic process GO:0009100 110 0.085
carbohydrate derivative biosynthetic process GO:1901137 207 0.084
negative regulation of multicellular organismal process GO:0051241 317 0.080
intracellular protein transport GO:0006886 270 0.075
nucleoside triphosphate catabolic process GO:0009143 394 0.070
glycoprotein biosynthetic process GO:0009101 91 0.070
divalent inorganic cation homeostasis GO:0072507 136 0.069
vesicle mediated transport GO:0016192 371 0.068
cell projection organization GO:0030030 252 0.064
Fly
regulation of cellular component movement GO:0051270 334 0.064
regulation of amyloid precursor protein biosynthetic process GO:0042984 4 0.063
chemical homeostasis GO:0048878 306 0.061
organophosphate biosynthetic process GO:0090407 163 0.058
lipid translocation GO:0034204 2 0.058
post golgi vesicle mediated transport GO:0006892 36 0.058
calcium ion homeostasis GO:0055074 122 0.056
vacuolar transport GO:0007034 34 0.056
cellular divalent inorganic cation homeostasis GO:0072503 128 0.054
system process GO:0003008 349 0.054
determination of adult lifespan GO:0008340 2 0.049
ribonucleotide catabolic process GO:0009261 405 0.048
regulation of locomotion GO:0040012 329 0.047
purine containing compound catabolic process GO:0072523 411 0.046
blood vessel morphogenesis GO:0048514 162 0.045
regulation of cell motility GO:2000145 299 0.044
regulation of immune response GO:0050776 201 0.042
anatomical structure formation involved in morphogenesis GO:0048646 284 0.041
apoptotic signaling pathway GO:0097190 268 0.040
protein localization to organelle GO:0033365 280 0.039
innate immune response GO:0045087 178 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.039
transmembrane transport GO:0055085 399 0.038
regulation of protein localization GO:0032880 296 0.038
cytoplasmic transport GO:0016482 379 0.038
purine ribonucleoside metabolic process GO:0046128 437 0.037
cellular ketone metabolic process GO:0042180 80 0.036
purine nucleoside catabolic process GO:0006152 398 0.035
organophosphate catabolic process GO:0046434 430 0.034
immune response GO:0006955 307 0.033
regulation of organelle transport along microtubule GO:1902513 2 0.033
actin filament based process GO:0030029 224 0.033
regulation of peptidase activity GO:0052547 180 0.032
female gamete generation GO:0007292 2 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
regulation of intracellular transport GO:0032386 195 0.032
regulation of cell projection organization GO:0031344 107 0.031
exocytosis GO:0006887 71 0.031
protein localization to membrane GO:0072657 160 0.031
regulation of mapk cascade GO:0043408 262 0.031
cellular amino acid metabolic process GO:0006520 116 0.030
cation transport GO:0006812 331 0.030
cellular calcium ion homeostasis GO:0006874 117 0.030
ribonucleoside triphosphate catabolic process GO:0009203 391 0.030
cellular amide metabolic process GO:0043603 69 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
negative regulation of hydrolase activity GO:0051346 182 0.030
regulation of secretion GO:0051046 194 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.029
tissue migration GO:0090130 119 0.029
regulation of purine nucleotide catabolic process GO:0033121 205 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
inorganic cation transmembrane transport GO:0098662 194 0.028
regulation of gtpase activity GO:0043087 180 0.028
positive regulation of transport GO:0051050 336 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.028
cell morphogenesis GO:0000902 296 0.027
regulation of defense response GO:0031347 154 0.026
multicellular organismal aging GO:0010259 3 0.026
ion homeostasis GO:0050801 230 0.026
negative regulation of protein metabolic process GO:0051248 391 0.025
actin cytoskeleton organization GO:0030036 207 0.025
positive regulation of immune response GO:0050778 159 0.025
response to growth factor GO:0070848 205 0.024
positive regulation of secretion GO:0051047 116 0.024
single organism membrane organization GO:0044802 268 0.024
biological adhesion GO:0022610 331 0.024
actin filament organization GO:0007015 128 0.024
regulation of cell migration GO:0030334 289 0.024
immune effector process GO:0002252 159 0.024
cellular amine metabolic process GO:0044106 41 0.024
regulation of cytoplasmic transport GO:1903649 149 0.024
neuromuscular junction development GO:0007528 3 0.023
golgi vesicle transport GO:0048193 80 0.023
positive regulation of developmental process GO:0051094 314 0.023
epithelium migration GO:0090132 119 0.023
carbohydrate metabolic process GO:0005975 207 0.023
negative regulation of catalytic activity GO:0043086 335 0.022
angiogenesis GO:0001525 147 0.022
cellular sodium ion homeostasis GO:0006883 8 0.022
mapk cascade GO:0000165 288 0.022
golgi ribbon formation GO:0090161 3 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
circulatory system development GO:0072359 262 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.021
regulation of cytoskeleton organization GO:0051493 177 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
positive regulation of immune system process GO:0002684 283 0.021
lymphocyte mediated immunity GO:0002449 48 0.021
regulation of secretion by cell GO:1903530 177 0.021
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
long term memory GO:0007616 2 0.021
neurogenesis GO:0022008 169 0.021
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
endomembrane system organization GO:0010256 196 0.020
hemopoiesis GO:0030097 180 0.020
lipid localization GO:0010876 106 0.020
peripheral nervous system development GO:0007422 2 0.020
positive regulation of catabolic process GO:0009896 310 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.019
regulation of actin polymerization or depolymerization GO:0008064 56 0.019
negative regulation of catabolic process GO:0009895 104 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
generation of neurons GO:0048699 152 0.018
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
negative regulation of peptidase activity GO:0010466 91 0.018
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.017
negative regulation of cell death GO:0060548 345 0.017
endocytosis GO:0006897 159 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
epithelium development GO:0060429 227 0.017
oogenesis GO:0048477 2 0.017
immune system development GO:0002520 195 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
growth GO:0040007 202 0.017
cell projection morphogenesis GO:0048858 129 0.016
ameboidal type cell migration GO:0001667 135 0.016
natural killer cell degranulation GO:0043320 2 0.016
actin polymerization or depolymerization GO:0008154 56 0.016
cardiovascular system development GO:0072358 262 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
regulation of proteolysis GO:0030162 293 0.016
regulation of cell differentiation GO:0045595 393 0.016
regulation of actin filament based process GO:0032970 141 0.016
defense response GO:0006952 315 0.016
regulation of protein transport GO:0051223 213 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
Fly
nucleoside catabolic process GO:0009164 408 0.016
amyloid precursor protein biosynthetic process GO:0042983 4 0.016
myeloid cell differentiation GO:0030099 117 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
regulation of cellular response to stress GO:0080135 244 0.015
interspecies interaction between organisms GO:0044419 156 0.015
positive regulation of cell death GO:0010942 263 0.015
regulation of cell activation GO:0050865 125 0.015
heparan sulfate proteoglycan metabolic process GO:0030201 12 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
secretion by cell GO:0032940 226 0.015
gtp catabolic process GO:0006184 237 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
rho protein signal transduction GO:0007266 26 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
regulation of transferase activity GO:0051338 355 0.014
divalent metal ion transport GO:0070838 152 0.014
protein maturation GO:0051604 233 0.014
wnt signaling pathway GO:0016055 156 0.014
regulation of organelle assembly GO:1902115 40 0.014
regulation of leukocyte mediated immunity GO:0002703 38 0.014
multi organism cellular process GO:0044764 156 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
actin filament capping GO:0051693 4 0.014
negative regulation of cell projection organization GO:0031345 22 0.014
neuron development GO:0048666 113 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
regulation of growth GO:0040008 165 0.014
granzyme mediated apoptotic signaling pathway GO:0008626 4 0.014
memory GO:0007613 3 0.014
cellular component disassembly GO:0022411 92 0.013
protein catabolic process GO:0030163 325 0.013
regulation of cell development GO:0060284 161 0.013
epithelial cell migration GO:0010631 119 0.013
microtubule based movement GO:0007018 32 0.013
negative regulation of blood pressure GO:0045776 3 0.013
cell development GO:0048468 328 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
regulation of protein catabolic process GO:0042176 155 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
blood vessel development GO:0001568 172 0.013
maintenance of location GO:0051235 112 0.013
plasma membrane organization GO:0007009 115 0.013
negative regulation of vasculature development GO:1901343 43 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
amine metabolic process GO:0009308 44 0.013
neuron projection development GO:0031175 106 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
regulation of anatomical structure size GO:0090066 101 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.012
anion transport GO:0006820 161 0.012
membrane lipid metabolic process GO:0006643 53 0.012
synaptic vesicle endocytosis GO:0048488 2 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
cell part morphogenesis GO:0032990 137 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
regulation of neurogenesis GO:0050767 82 0.012
positive regulation of protein transport GO:0051222 135 0.012
cell projection assembly GO:0030031 126 0.012
response to bacterium GO:0009617 144 0.012
regulation of neuron projection development GO:0010975 57 0.012
regulation of actin filament length GO:0030832 56 0.012
proteoglycan metabolic process GO:0006029 29 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
cellular response to glucocorticoid stimulus GO:0071385 4 0.012
regulation of protein maturation GO:1903317 150 0.012
leukocyte activation GO:0045321 164 0.012
cell activation GO:0001775 213 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
response to salt stress GO:0009651 3 0.012
protein stabilization GO:0050821 64 0.012
divalent inorganic cation transport GO:0072511 158 0.012
monocyte activation GO:0042117 3 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
viral process GO:0016032 146 0.011
positive regulation of keratinocyte migration GO:0051549 4 0.011
negative regulation of protein maturation GO:1903318 142 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
nervous system development GO:0007399 293 0.011
regulation of cytokine production GO:0001817 232 0.011
segmentation GO:0035282 4 0.011
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 19 0.011
macromolecule glycosylation GO:0043413 63 0.011
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.011
amyloid precursor protein metabolic process GO:0042982 17 0.011
negative regulation of amyloid precursor protein biosynthetic process GO:0042985 2 0.011
positive regulation of proteolysis GO:0045862 142 0.011
regulation of rho protein signal transduction GO:0035023 79 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
cellular protein complex disassembly GO:0043624 36 0.011
reproductive process GO:0022414 106 0.011
cell adhesion GO:0007155 325 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
negative regulation of complement activation classical pathway GO:0045959 3 0.011
nucleotide catabolic process GO:0009166 408 0.010
response to fibroblast growth factor GO:0071774 39 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
interleukin 8 production GO:0032637 51 0.010
regulation of lipid metabolic process GO:0019216 96 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
response to hormone GO:0009725 175 0.010
regulation of response to external stimulus GO:0032101 222 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
organic anion transport GO:0015711 103 0.010
positive regulation of cell proliferation GO:0008284 301 0.010

ATP6AP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.709
lysosomal storage disease DOID:3211 47 0.506
inherited metabolic disorder DOID:655 242 0.506
central nervous system disease DOID:331 186 0.080
nervous system disease DOID:863 431 0.080
brain disease DOID:936 73 0.053
epilepsy syndrome DOID:1826 41 0.045
variable age at onset electroclinical syndrome DOID:0050706 8 0.045
electroclinical syndrome DOID:0050701 32 0.045
progressive myoclonus epilepsy DOID:891 8 0.045
sensory system disease DOID:0050155 203 0.042
retinal disease DOID:5679 118 0.040
eye and adnexa disease DOID:1492 150 0.040
eye disease DOID:5614 149 0.040
cerebral degeneration DOID:1443 16 0.032
musculoskeletal system disease DOID:17 223 0.027
connective tissue disease DOID:65 109 0.023
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
mucopolysaccharidosis DOID:12798 11 0.013
bone development disease DOID:0080006 55 0.012
bone disease DOID:0080001 88 0.012
neurodegenerative disease DOID:1289 102 0.010