Homo sapiens

6 known processes

SIX5

SIX homeobox 5

(Aliases: BOR2,DMAHP)

SIX5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron fate commitment GO:0048663 2 0.242
regulation of cell differentiation GO:0045595 393 0.192
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.182
positive regulation of developmental process GO:0051094 314 0.182
nervous system development GO:0007399 293 0.157
Human Fly
cell development GO:0048468 328 0.146
Mouse Fly
stem cell differentiation GO:0048863 93 0.133
cell fate determination GO:0001709 3 0.129
negative regulation of multicellular organismal process GO:0051241 317 0.113
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.103
negative regulation of developmental process GO:0051093 247 0.101
epithelium development GO:0060429 227 0.100
negative regulation of programmed cell death GO:0043069 321 0.099
tube morphogenesis GO:0035239 95 0.098
Worm
forebrain generation of neurons GO:0021872 3 0.097
cell morphogenesis GO:0000902 296 0.093
Fly
embryonic morphogenesis GO:0048598 85 0.083
Worm
organ morphogenesis GO:0009887 147 0.081
negative regulation of cell proliferation GO:0008285 228 0.079
Mouse
cellular component morphogenesis GO:0032989 314 0.077
Fly
circulatory system development GO:0072359 262 0.076
negative regulation of cell death GO:0060548 345 0.073
cardiovascular system development GO:0072358 262 0.070
negative regulation of cell differentiation GO:0045596 171 0.065
negative regulation of apoptotic process GO:0043066 316 0.064
metencephalon development GO:0022037 2 0.062
regulation of cellular amino acid metabolic process GO:0006521 6 0.061
post embryonic development GO:0009791 2 0.061
cellular ketone metabolic process GO:0042180 80 0.060
cellular amino acid metabolic process GO:0006520 116 0.058
regulation of cell development GO:0060284 161 0.058
amine metabolic process GO:0009308 44 0.055
somatic stem cell maintenance GO:0035019 4 0.054
response to oxygen containing compound GO:1901700 369 0.053
cytoplasmic transport GO:0016482 379 0.053
regulation of cellular ketone metabolic process GO:0010565 50 0.052
positive regulation of cell differentiation GO:0045597 211 0.052
central nervous system development GO:0007417 123 0.051
Human
segmentation GO:0035282 4 0.051
cellular response to oxygen containing compound GO:1901701 276 0.051
muscle cell fate commitment GO:0042693 4 0.050
anatomical structure formation involved in morphogenesis GO:0048646 284 0.050
Worm Fly
positive regulation of transport GO:0051050 336 0.049
neurogenesis GO:0022008 169 0.049
Fly
generation of neurons GO:0048699 152 0.049
Fly
skeletal system development GO:0001501 79 0.049
regulation of cell cycle process GO:0010564 266 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
pattern specification process GO:0007389 43 0.047
Human
organ formation GO:0048645 3 0.046
regulation of protein localization GO:0032880 296 0.045
secretion GO:0046903 254 0.044
hindbrain development GO:0030902 3 0.044
cell differentiation in spinal cord GO:0021515 1 0.044
regulation of locomotion GO:0040012 329 0.043
spinal cord development GO:0021510 4 0.043
kidney development GO:0001822 53 0.042
Human
locomotory behavior GO:0007626 1 0.042
positive regulation of catabolic process GO:0009896 310 0.042
multicellular organismal aging GO:0010259 3 0.041
system process GO:0003008 349 0.041
organonitrogen compound biosynthetic process GO:1901566 200 0.041
regulation of cell cycle GO:0051726 393 0.041
behavior GO:0007610 112 0.041
determination of adult lifespan GO:0008340 2 0.041
female gamete generation GO:0007292 2 0.040
actin filament based process GO:0030029 224 0.040
regulation of establishment of protein localization GO:0070201 242 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.040
inner ear morphogenesis GO:0042472 4 0.039
cell projection organization GO:0030030 252 0.038
Fly
sebaceous gland development GO:0048733 1 0.038
neuron differentiation GO:0030182 138 0.038
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.037
tube development GO:0035295 125 0.037
Worm
regulation of purine nucleotide metabolic process GO:1900542 264 0.037
neural crest cell development GO:0014032 3 0.037
purine nucleoside catabolic process GO:0006152 398 0.037
lipid metabolic process GO:0006629 381 0.037
cellular response to dna damage stimulus GO:0006974 379 0.037
forelimb morphogenesis GO:0035136 4 0.036
morphogenesis of embryonic epithelium GO:0016331 4 0.036
regulation of nervous system development GO:0051960 88 0.035
vasculature development GO:0001944 181 0.035
regulation of cell migration GO:0030334 289 0.034
mitotic cell cycle GO:0000278 326 0.034
single organism cellular localization GO:1902580 332 0.034
positive regulation of gtpase activity GO:0043547 166 0.034
cell division GO:0051301 168 0.034
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
response to abiotic stimulus GO:0009628 336 0.033
heart formation GO:0060914 2 0.033
vesicle mediated transport GO:0016192 371 0.033
adult locomotory behavior GO:0008344 1 0.032
biological adhesion GO:0022610 331 0.032
regulation of ossification GO:0030278 58 0.032
stem cell development GO:0048864 69 0.031
tissue morphogenesis GO:0048729 96 0.031
Worm
taxis GO:0042330 157 0.030
cell proliferation in forebrain GO:0021846 1 0.030
heart development GO:0007507 95 0.030
positive regulation of cell migration GO:0030335 172 0.030
nucleotide catabolic process GO:0009166 408 0.030
cellular macromolecular complex assembly GO:0034622 324 0.029
positive regulation of locomotion GO:0040017 186 0.029
positive regulation of cellular component organization GO:0051130 376 0.029
hematopoietic or lymphoid organ development GO:0048534 186 0.029
pituitary gland development GO:0021983 2 0.029
head development GO:0060322 108 0.029
Human
positive regulation of cell proliferation GO:0008284 301 0.029
ribonucleoside catabolic process GO:0042454 406 0.028
reproductive process GO:0022414 106 0.028
Mouse Fly
positive regulation of protein phosphorylation GO:0001934 313 0.028
glycosyl compound catabolic process GO:1901658 413 0.028
heart morphogenesis GO:0003007 48 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
epithelial cell differentiation GO:0030855 141 0.028
cellular amine metabolic process GO:0044106 41 0.028
enzyme linked receptor protein signaling pathway GO:0007167 303 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
blastoderm segmentation GO:0007350 2 0.027
mesenchymal cell development GO:0014031 50 0.027
morphogenesis of an epithelium GO:0002009 60 0.027
peripheral nervous system development GO:0007422 2 0.027
nucleoside catabolic process GO:0009164 408 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
muscle structure development GO:0061061 98 0.026
Fly
urogenital system development GO:0001655 65 0.026
Human
neurological system process GO:0050877 163 0.026
apoptotic signaling pathway GO:0097190 268 0.026
negative regulation of cell cycle GO:0045786 193 0.026
immune system development GO:0002520 195 0.026
embryonic placenta development GO:0001892 1 0.026
positive regulation of apoptotic process GO:0043065 246 0.026
cell morphogenesis involved in differentiation GO:0000904 144 0.026
organophosphate catabolic process GO:0046434 430 0.026
secretion by cell GO:0032940 226 0.025
cell cell signaling GO:0007267 155 0.025
membrane organization GO:0061024 292 0.025
regulation of cell morphogenesis GO:0022604 153 0.025
compound eye development GO:0048749 1 0.025
oogenesis GO:0048477 2 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
cellular lipid metabolic process GO:0044255 303 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
regulation of nucleotide metabolic process GO:0006140 269 0.025
renal system development GO:0072001 63 0.025
Human
positive regulation of phosphorylation GO:0042327 394 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
cell projection morphogenesis GO:0048858 129 0.024
Fly
specification of organ identity GO:0010092 3 0.024
cell growth GO:0016049 160 0.024
regulation of growth GO:0040008 165 0.024
positive regulation of organelle organization GO:0010638 195 0.024
menstrual cycle phase GO:0022601 2 0.024
brain development GO:0007420 97 0.024
Human
nephric duct development GO:0072176 4 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
positive regulation of cell motility GO:2000147 177 0.023
endomembrane system organization GO:0010256 196 0.023
regulation of mapk cascade GO:0043408 262 0.023
second messenger mediated signaling GO:0019932 78 0.023
purine ribonucleotide catabolic process GO:0009154 404 0.023
regulation of gtpase activity GO:0043087 180 0.023
forebrain regionalization GO:0021871 3 0.022
Human
regulation of neuron differentiation GO:0045664 70 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
nucleocytoplasmic transport GO:0006913 176 0.022
gtp metabolic process GO:0046039 239 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
ossification GO:0001503 121 0.022
limbic system development GO:0021761 3 0.022
negative regulation of protein metabolic process GO:0051248 391 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
cell part morphogenesis GO:0032990 137 0.022
Fly
embryonic epithelial tube formation GO:0001838 4 0.022
anterior posterior axis specification GO:0009948 2 0.022
metal ion transport GO:0030001 272 0.021
osteoblast differentiation GO:0001649 92 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.021
regulation of neurogenesis GO:0050767 82 0.021
mesenchyme development GO:0060485 59 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
regulation of cellular response to stress GO:0080135 244 0.021
nerve development GO:0021675 4 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
regulation of cell motility GO:2000145 299 0.021
growth GO:0040007 202 0.021
neuromuscular junction development GO:0007528 3 0.021
sex determination GO:0007530 3 0.021
regulation of proteolysis GO:0030162 293 0.021
negative regulation of testicular blood vessel morphogenesis GO:0061369 1 0.021
monovalent inorganic cation transport GO:0015672 128 0.020
regulation of transferase activity GO:0051338 355 0.020
covalent chromatin modification GO:0016569 254 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
dephosphorylation GO:0016311 209 0.020
embryo development GO:0009790 123 0.020
Worm
single organism membrane organization GO:0044802 268 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.020
positive regulation of proteolysis GO:0045862 142 0.020
response to cytokine GO:0034097 232 0.020
regulation of cell growth GO:0001558 135 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
forebrain neuron differentiation GO:0021879 3 0.020
nuclear transport GO:0051169 179 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
regulation of intracellular transport GO:0032386 195 0.020
regionalization GO:0003002 29 0.020
Human
epithelial tube morphogenesis GO:0060562 38 0.020
regulation of protein transport GO:0051223 213 0.020
inorganic ion transmembrane transport GO:0098660 231 0.020
blood vessel morphogenesis GO:0048514 162 0.019
embryonic forelimb morphogenesis GO:0035115 4 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
hemopoiesis GO:0030097 180 0.019
regulation of cellular component movement GO:0051270 334 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.019
actin cytoskeleton organization GO:0030036 207 0.019
positive regulation of cell development GO:0010720 92 0.019
skeletal system morphogenesis GO:0048705 24 0.019
regulation of cytoplasmic transport GO:1903649 149 0.019
mitotic cell cycle process GO:1903047 286 0.019
protein catabolic process GO:0030163 325 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
wnt signaling pathway GO:0016055 156 0.019
positive regulation of cell death GO:0010942 263 0.019
regulation of cell division GO:0051302 116 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
cell adhesion GO:0007155 325 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
rna processing GO:0006396 255 0.018
protein localization to membrane GO:0072657 160 0.018
single organism reproductive process GO:0044702 98 0.018
Mouse Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.018
regulation of gtp catabolic process GO:0033124 180 0.018
convergent extension GO:0060026 1 0.018
regulation of secretion by cell GO:1903530 177 0.018
muscle contraction GO:0006936 73 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
negative regulation of transport GO:0051051 176 0.018
digestive tract development GO:0048565 75 0.018
Worm
positive regulation of glucocorticoid metabolic process GO:0031945 1 0.018
positive regulation of nervous system development GO:0051962 54 0.018
regulation of epithelial cell proliferation GO:0050678 113 0.018
circadian behavior GO:0048512 2 0.018
sensory perception GO:0007600 103 0.018
cerebellum development GO:0021549 2 0.018
regulation of membrane potential GO:0042391 95 0.018
ventral spinal cord development GO:0021517 1 0.017
neuron projection development GO:0031175 106 0.017
Fly
positive regulation of programmed cell death GO:0043068 249 0.017
behavioral response to ethanol GO:0048149 2 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
regulation of lipid metabolic process GO:0019216 96 0.017
signal release GO:0023061 70 0.017
negative regulation of cell development GO:0010721 48 0.017
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.017
hematopoietic stem cell differentiation GO:0060218 4 0.017
somitogenesis GO:0001756 2 0.017
neural crest cell migration GO:0001755 2 0.017
canonical wnt signaling pathway GO:0060070 116 0.017
organelle assembly GO:0070925 176 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
regulation of osteoblast differentiation GO:0045667 38 0.017
ion homeostasis GO:0050801 230 0.017
transmembrane transport GO:0055085 399 0.017
chemotaxis GO:0006935 157 0.016
small molecule biosynthetic process GO:0044283 157 0.016
morphogenesis of a polarized epithelium GO:0001738 3 0.016
rhythmic behavior GO:0007622 2 0.016
cardiac muscle tissue development GO:0048738 39 0.016
cell cycle phase transition GO:0044770 173 0.016
positive regulation of odontogenesis GO:0042482 3 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
regulation of actin filament based process GO:0032970 141 0.016
spermatid differentiation GO:0048515 4 0.016
Mouse
lipid biosynthetic process GO:0008610 177 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
cranial nerve development GO:0021545 4 0.016
sleep GO:0030431 2 0.016
cardiac right ventricle morphogenesis GO:0003215 3 0.016
heart field specification GO:0003128 2 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
histone modification GO:0016570 251 0.016
response to external biotic stimulus GO:0043207 261 0.016
neuron development GO:0048666 113 0.015
Fly
glial cell migration GO:0008347 4 0.015
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.015
primary neural tube formation GO:0014020 3 0.015
mapk cascade GO:0000165 288 0.015
cellular amide metabolic process GO:0043603 69 0.015
positive regulation of cell cycle GO:0045787 140 0.015
regulation of homeostatic process GO:0032844 121 0.015
cellular protein catabolic process GO:0044257 261 0.015
viral process GO:0016032 146 0.015
mesenchymal cell differentiation GO:0048762 52 0.015
memory GO:0007613 3 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
cardiac cell fate determination GO:0060913 3 0.015
intracellular protein transport GO:0006886 270 0.015
chromatin modification GO:0016568 298 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
interspecies interaction between organisms GO:0044419 156 0.015
positive regulation of cellular component movement GO:0051272 181 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
multi organism cellular process GO:0044764 156 0.015
sensory perception of pain GO:0019233 4 0.015
positive regulation of intracellular transport GO:0032388 104 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
Fly
blood vessel development GO:0001568 172 0.015
protein localization to plasma membrane GO:0072659 93 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
positive regulation of neurogenesis GO:0050769 49 0.015
protein acylation GO:0043543 138 0.014
sequestering of metal ion GO:0051238 24 0.014
purine nucleotide biosynthetic process GO:0006164 84 0.014
cyclic nucleotide metabolic process GO:0009187 82 0.014
kidney epithelium development GO:0072073 25 0.014
nitrogen compound transport GO:0071705 191 0.014
axis elongation GO:0003401 4 0.014
regulation of secretion GO:0051046 194 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
cation transmembrane transport GO:0098655 238 0.014
divalent metal ion transport GO:0070838 152 0.014
ras protein signal transduction GO:0007265 73 0.014
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
negative regulation of gliogenesis GO:0014014 3 0.014
positive regulation of tooth mineralization GO:0070172 2 0.014
cell fate commitment GO:0045165 27 0.014
Worm
circulatory system process GO:0003013 113 0.014
regulation of male gonad development GO:2000018 4 0.014
regulation of actin cytoskeleton organization GO:0032956 116 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
protein import into nucleus GO:0006606 104 0.014
regulation of kinase activity GO:0043549 314 0.014
regulation of protein catabolic process GO:0042176 155 0.014
immune response GO:0006955 307 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
negative regulation of wnt signaling pathway GO:0030178 69 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
viral life cycle GO:0019058 132 0.014
myeloid cell differentiation GO:0030099 117 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
secondary heart field specification GO:0003139 2 0.014
protein targeting GO:0006605 187 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
regulation of hormone levels GO:0010817 125 0.014
sensory organ development GO:0007423 52 0.014
Human Mouse
cytokine production GO:0001816 247 0.014
cellular cation homeostasis GO:0030003 163 0.014
coagulation GO:0050817 78 0.014
endodermal cell fate specification GO:0001714 4 0.013
regulation of canonical wnt signaling pathway GO:0060828 88 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.013
metal ion homeostasis GO:0055065 169 0.013
pericardium development GO:0060039 2 0.013
regulation of response to external stimulus GO:0032101 222 0.013
neural tube formation GO:0001841 3 0.013
gtp catabolic process GO:0006184 237 0.013
regulation of glial cell differentiation GO:0045685 3 0.013
regulation of myeloid cell differentiation GO:0045637 81 0.013
gastrulation with mouth forming second GO:0001702 1 0.013
cardiac muscle cell fate commitment GO:0060923 4 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
protein ubiquitination GO:0016567 314 0.013
cellular homeostasis GO:0019725 196 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
digestive system development GO:0055123 75 0.013
Worm
spermatid development GO:0007286 4 0.013
Mouse
guanosine containing compound metabolic process GO:1901068 244 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
chromatin organization GO:0006325 351 0.013
dna repair GO:0006281 198 0.013
regulation of stem cell differentiation GO:2000736 56 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.013
maintenance of location GO:0051235 112 0.013
protein oligomerization GO:0051259 173 0.013
somatic muscle development GO:0007525 1 0.013
mating GO:0007618 1 0.013
positive regulation of gliogenesis GO:0014015 4 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
response to axon injury GO:0048678 1 0.013
embryonic organ development GO:0048568 36 0.013
cartilage development GO:0051216 31 0.013
amide transport GO:0042886 76 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
purine containing compound catabolic process GO:0072523 411 0.012
angiogenesis GO:0001525 147 0.012
organic acid biosynthetic process GO:0016053 97 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
protein targeting to nucleus GO:0044744 104 0.012
regeneration GO:0031099 4 0.012
protein maturation GO:0051604 233 0.012
cellular chemical homeostasis GO:0055082 180 0.012
positive regulation of ossification GO:0045778 32 0.012
tripartite regional subdivision GO:0007351 2 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of meiosis GO:0040020 3 0.012
hippocampus development GO:0021766 1 0.012
myoblast fusion GO:0007520 1 0.012
Fly
cation homeostasis GO:0055080 189 0.012
oocyte development GO:0048599 1 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
asymmetric stem cell division GO:0098722 1 0.012
regulation of protein kinase activity GO:0045859 289 0.012
multi organism reproductive process GO:0044703 54 0.012
Mouse
oocyte differentiation GO:0009994 2 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
chemical homeostasis GO:0048878 306 0.012
regulation of multi organism process GO:0043900 157 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.012
divalent inorganic cation transport GO:0072511 158 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.012
regulation of calcium ion transport GO:0051924 79 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
nuclear export GO:0051168 69 0.012
plasma membrane organization GO:0007009 115 0.012
cytokinesis GO:0000910 96 0.012
nuclear import GO:0051170 106 0.012
stem cell division GO:0017145 2 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
cellular protein complex assembly GO:0043623 188 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
midgut development GO:0007494 1 0.012
long term memory GO:0007616 2 0.012
regulation of cell adhesion GO:0030155 166 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
cell activation GO:0001775 213 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
peptidyl lysine modification GO:0018205 144 0.012
ion transmembrane transport GO:0034220 338 0.012
regulation of transmembrane transport GO:0034762 139 0.012
mitochondrion organization GO:0007005 156 0.011
positive regulation of cytoplasmic transport GO:1903651 82 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
positive regulation of immune system process GO:0002684 283 0.011
developmental process involved in reproduction GO:0003006 66 0.011
Mouse Fly
receptor metabolic process GO:0043112 81 0.011
connective tissue development GO:0061448 39 0.011
Fly
protein import GO:0017038 130 0.011
regulation of nucleocytoplasmic transport GO:0046822 98 0.011
establishment of protein localization to plasma membrane GO:0090002 68 0.011
regulation of ion homeostasis GO:2000021 73 0.011
brain morphogenesis GO:0048854 1 0.011
response to wounding GO:0009611 168 0.011
cell fate specification GO:0001708 8 0.011
Worm
regulation of postsynaptic membrane potential GO:0060078 1 0.011
regulation of multicellular organismal metabolic process GO:0044246 17 0.011
single organism nuclear import GO:1902593 104 0.011
oxidation reduction process GO:0055114 396 0.011
myosin filament organization GO:0031033 2 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
regulation of wnt signaling pathway involved in heart development GO:0003307 3 0.011
neurotransmitter secretion GO:0007269 4 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.011
associative learning GO:0008306 1 0.011
cartilage condensation GO:0001502 1 0.011
cation transport GO:0006812 331 0.011
response to oxygen levels GO:0070482 100 0.011

SIX5 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.043
sensory system disease DOID:0050155 203 0.042
Human
eye and adnexa disease DOID:1492 150 0.042
nervous system disease DOID:863 431 0.042
Human
eye disease DOID:5614 149 0.042
myopathy DOID:423 104 0.020
muscular disease DOID:0080000 114 0.020
muscle tissue disease DOID:66 113 0.020
disease of metabolism DOID:0014667 295 0.016
retinal disease DOID:5679 118 0.014
central nervous system disease DOID:331 186 0.013
retinal degeneration DOID:8466 89 0.012
neurodegenerative disease DOID:1289 102 0.012
muscular dystrophy DOID:9884 51 0.011