Homo sapiens

78 known processes

DDX60

DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

(Aliases: FLJ10787,FLJ20035)

DDX60 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of rig i signaling pathway GO:1900246 4 0.998
defense response to virus GO:0051607 71 0.981
response to other organism GO:0051707 261 0.927
positive regulation of cytokine production GO:0001819 167 0.914
response to biotic stimulus GO:0009607 276 0.899
multi organism cellular process GO:0044764 156 0.868
cytokine production GO:0001816 247 0.864
regulation of defense response to virus GO:0050688 33 0.861
viral life cycle GO:0019058 132 0.846
defense response to other organism GO:0098542 129 0.834
pattern recognition receptor signaling pathway GO:0002221 48 0.800
immune response GO:0006955 307 0.773
response to external biotic stimulus GO:0043207 261 0.750
response to virus GO:0009615 126 0.674
negative regulation of viral process GO:0048525 66 0.633
regulation of defense response GO:0031347 154 0.625
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.616
regulation of response to biotic stimulus GO:0002831 55 0.614
activation of innate immune response GO:0002218 55 0.602
defense response GO:0006952 315 0.595
regulation of multi organism process GO:0043900 157 0.594
positive regulation of multi organism process GO:0043902 56 0.583
intracellular receptor signaling pathway GO:0030522 104 0.553
response to cytokine GO:0034097 232 0.542
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.540
interspecies interaction between organisms GO:0044419 156 0.494
positive regulation of defense response GO:0031349 87 0.474
immune effector process GO:0002252 159 0.466
innate immune response GO:0045087 178 0.425
protein modification by small protein conjugation GO:0032446 342 0.407
positive regulation of interferon beta production GO:0032728 17 0.400
immune response activating signal transduction GO:0002757 90 0.386
regulation of cytokine production GO:0001817 232 0.353
posttranscriptional regulation of gene expression GO:0010608 213 0.352
regulation of establishment of protein localization GO:0070201 242 0.352
intracellular transport of virus GO:0075733 14 0.326
regulation of defense response to virus by host GO:0050691 22 0.299
regulation of intracellular transport GO:0032386 195 0.298
interleukin 2 secretion GO:0070970 3 0.297
negative regulation of viral genome replication GO:0045071 35 0.289
rig i signaling pathway GO:0039529 7 0.284
regulation of protein transport GO:0051223 213 0.269
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.265
intracellular protein transport GO:0006886 270 0.259
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.258
innate immune response activating signal transduction GO:0002758 48 0.242
fas signaling pathway GO:0036337 3 0.238
regulation of immune effector process GO:0002697 91 0.219
regulation of protein localization GO:0032880 296 0.211
mda 5 signaling pathway GO:0039530 4 0.210
secretion GO:0046903 254 0.208
multi organism transport GO:0044766 14 0.200
protein oligomerization GO:0051259 173 0.185
regulation of viral genome replication GO:0045069 48 0.184
multi organism intracellular transport GO:1902583 14 0.183
immune response regulating signaling pathway GO:0002764 97 0.180
positive regulation of intracellular protein transport GO:0090316 76 0.176
response to dsrna GO:0043331 25 0.173
regulation of response to external stimulus GO:0032101 222 0.166
rna interference GO:0016246 4 0.162
positive regulation of type i interferon production GO:0032481 20 0.148
positive regulation of immune system process GO:0002684 283 0.145
viral process GO:0016032 146 0.145
regulation of innate immune response GO:0045088 97 0.142
negative regulation of catalytic activity GO:0043086 335 0.138
viral genome replication GO:0019079 50 0.138
protein polyubiquitination GO:0000209 110 0.133
negative regulation of transport GO:0051051 176 0.131
regulation of type i interferon production GO:0032479 26 0.129
negative regulation of defense response to virus GO:0050687 10 0.129
cellular response to dsrna GO:0071359 19 0.127
positive regulation of interferon alpha production GO:0032727 11 0.122
negative regulation of defense response to virus by host GO:0050689 4 0.122
regulation of viral process GO:0050792 103 0.121
nuclear transport GO:0051169 179 0.118
positive regulation of intracellular transport GO:0032388 104 0.117
glycosylation GO:0070085 71 0.111
positive regulation of cell death GO:0010942 263 0.111
positive regulation of immune response GO:0050778 159 0.108
single organism nuclear import GO:1902593 104 0.107
negative regulation of cell proliferation GO:0008285 228 0.105
negative regulation of multi organism process GO:0043901 92 0.103
negative regulation of intracellular transport of viral material GO:1901253 2 0.103
activation of immune response GO:0002253 114 0.098
cytoplasmic transport GO:0016482 379 0.093
regulation of intracellular protein transport GO:0033157 123 0.087
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.086
protein maturation GO:0051604 233 0.086
posttranscriptional gene silencing GO:0016441 25 0.085
regulation of immune response GO:0050776 201 0.084
regulation of protein targeting GO:1903533 91 0.082
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.078
regulation of secretion by cell GO:1903530 177 0.076
regulation of protein localization to nucleus GO:1900180 85 0.075
regulation of protein ubiquitination GO:0031396 95 0.071
nucleoside phosphate biosynthetic process GO:1901293 109 0.069
positive regulation of transport GO:0051050 336 0.069
negative regulation of protein secretion GO:0050709 29 0.067
positive regulation of protein transport GO:0051222 135 0.067
protein deubiquitination GO:0016579 79 0.067
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.066
regulation of rig i signaling pathway GO:0039535 6 0.065
cellular response to nitrogen compound GO:1901699 144 0.065
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.065
intracellular transport of viral protein in host cell GO:0019060 4 0.064
response to nitrogen compound GO:1901698 184 0.064
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.064
multi organism metabolic process GO:0044033 41 0.064
positive regulation of programmed cell death GO:0043068 249 0.064
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.060
protein autoubiquitination GO:0051865 37 0.060
gene silencing by mirna GO:0035195 23 0.059
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.059
calcium ion transport GO:0006816 147 0.058
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.057
interaction with host GO:0051701 42 0.057
regulation of protein secretion GO:0050708 86 0.056
negative regulation of multicellular organismal process GO:0051241 317 0.056
regulation of protein import into nucleus GO:0042306 78 0.056
negative regulation of protein maturation GO:1903318 142 0.055
protein import into nucleus GO:0006606 104 0.055
positive regulation of viral entry into host cell GO:0046598 3 0.054
negative regulation of secretion GO:0051048 58 0.054
regulation of interleukin 2 secretion GO:1900040 2 0.054
chemical homeostasis GO:0048878 306 0.053
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.052
vesicle mediated transport GO:0016192 371 0.050
transport of virus GO:0046794 14 0.050
negative regulation of protein deubiquitination GO:0090086 3 0.050
positive regulation of innate immune response GO:0045089 79 0.049
response to organic cyclic compound GO:0014070 204 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.049
regulation of nucleocytoplasmic transport GO:0046822 98 0.048
protein targeting to nucleus GO:0044744 104 0.048
transmembrane transport GO:0055085 399 0.047
intracellular protein transport in other organism involved in symbiotic interaction GO:0051708 4 0.047
protein targeting GO:0006605 187 0.047
single organism cellular localization GO:1902580 332 0.046
regulation of protein processing GO:0070613 150 0.046
negative regulation of protein metabolic process GO:0051248 391 0.046
positive regulation of phosphorylation GO:0042327 394 0.045
positive regulation of hydrolase activity GO:0051345 331 0.045
positive regulation of protein complex assembly GO:0031334 86 0.045
regulation of apoptotic signaling pathway GO:2001233 175 0.045
negative regulation of programmed cell death GO:0043069 321 0.044
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 3 0.044
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.044
negative regulation of protein ubiquitination GO:0031397 35 0.044
protein modification by small protein removal GO:0070646 92 0.043
negative regulation of immune system process GO:0002683 136 0.042
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.042
positive regulation of proteolysis GO:0045862 142 0.042
extrinsic apoptotic signaling pathway GO:0097191 119 0.042
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.041
regulation of intracellular transport of viral material GO:1901252 2 0.041
carbohydrate derivative biosynthetic process GO:1901137 207 0.041
nucleocytoplasmic transport GO:0006913 176 0.040
regulation of binding GO:0051098 111 0.040
apoptotic signaling pathway GO:0097190 268 0.040
cellular response to interferon alpha GO:0035457 4 0.039
regulation by virus of viral protein levels in host cell GO:0046719 4 0.039
positive regulation of mapk cascade GO:0043410 190 0.038
response to molecule of bacterial origin GO:0002237 82 0.038
regulation of secretion GO:0051046 194 0.037
macromolecule glycosylation GO:0043413 63 0.037
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.037
regulation of proteolysis GO:0030162 293 0.036
retrograde transport endosome to golgi GO:0042147 45 0.036
cellular response to cytokine stimulus GO:0071345 181 0.036
modification dependent macromolecule catabolic process GO:0043632 212 0.035
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.034
negative regulation of response to biotic stimulus GO:0002832 18 0.034
negative regulation of defense response GO:0031348 47 0.034
negative regulation of hydrolase activity GO:0051346 182 0.034
protein ubiquitination GO:0016567 314 0.034
positive regulation of apoptotic process GO:0043065 246 0.034
cellular response to organic cyclic compound GO:0071407 127 0.032
regulation of cell differentiation GO:0045595 393 0.032
regulation of locomotion GO:0040012 329 0.032
positive regulation of cellular component organization GO:0051130 376 0.032
protein secretion GO:0009306 98 0.032
endosomal transport GO:0016197 129 0.031
negative regulation of intracellular protein transport GO:0090317 42 0.031
multi organism localization GO:1902579 14 0.031
regulation of cellular component biogenesis GO:0044087 281 0.031
extracellular transport GO:0006858 4 0.030
cellular macromolecular complex assembly GO:0034622 324 0.030
positive regulation of catabolic process GO:0009896 310 0.029
secretion by cell GO:0032940 226 0.029
regulation of tumor necrosis factor production GO:0032680 43 0.029
negative regulation of binding GO:0051100 57 0.029
negative regulation of cell death GO:0060548 345 0.029
ribonucleoprotein complex assembly GO:0022618 78 0.028
organonitrogen compound biosynthetic process GO:1901566 200 0.028
carbohydrate metabolic process GO:0005975 207 0.028
regulation of cytoplasmic transport GO:1903649 149 0.027
regulation of transmembrane transport GO:0034762 139 0.027
cellular response to virus GO:0098586 9 0.027
negative regulation of intracellular transport GO:0032387 60 0.027
positive regulation of viral process GO:0048524 37 0.027
negative regulation of proteolysis GO:0045861 132 0.027
protein sumoylation GO:0016925 25 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
negative regulation of apoptotic process GO:0043066 316 0.026
regulation of cysteine type endopeptidase activity GO:2000116 127 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
organophosphate catabolic process GO:0046434 430 0.025
mitotic cell cycle process GO:1903047 286 0.024
regulation of protein deubiquitination GO:0090085 4 0.024
regulation of gene expression epigenetic GO:0040029 73 0.024
immune system development GO:0002520 195 0.024
protein k63 linked ubiquitination GO:0070534 31 0.024
chromatin organization GO:0006325 351 0.024
response to bacterium GO:0009617 144 0.023
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.023
negative regulation of calcium ion import GO:0090281 1 0.023
regulation of transferase activity GO:0051338 355 0.023
cellular response to molecule of bacterial origin GO:0071219 62 0.023
negative regulation of type i interferon production GO:0032480 5 0.023
protein processing GO:0016485 226 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
mapk cascade GO:0000165 288 0.022
regulation of fas signaling pathway GO:1902044 2 0.022
response to exogenous dsrna GO:0043330 10 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
calcium ion import GO:0070509 23 0.022
cation transport GO:0006812 331 0.022
protein localization to nucleus GO:0034504 136 0.022
ion transmembrane transport GO:0034220 338 0.022
cellular response to biotic stimulus GO:0071216 71 0.022
regulation of mda 5 signaling pathway GO:0039533 4 0.022
negative regulation of cytokine production GO:0001818 82 0.022
double strand break repair GO:0006302 101 0.021
positive regulation of cytoskeleton organization GO:0051495 83 0.021
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.021
regulation of protein complex assembly GO:0043254 147 0.020
nuclear import GO:0051170 106 0.020
positive regulation of apoptotic signaling pathway GO:2001235 70 0.020
chromatin modification GO:0016568 298 0.020
negative regulation of transmembrane transport GO:0034763 29 0.020
nucleotide catabolic process GO:0009166 408 0.019
ncrna metabolic process GO:0034660 108 0.019
single organism membrane organization GO:0044802 268 0.019
n glycan processing GO:0006491 3 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
negative regulation of interleukin 2 secretion GO:1900041 2 0.018
glycoprotein metabolic process GO:0009100 110 0.018
divalent metal ion transport GO:0070838 152 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
hemopoiesis GO:0030097 180 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
purine containing compound catabolic process GO:0072523 411 0.018
negative regulation of transferase activity GO:0051348 124 0.018
dna repair GO:0006281 198 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.017
regulation of peptidase activity GO:0052547 180 0.017
regulation of dna metabolic process GO:0051052 153 0.017
positive regulation of transferase activity GO:0051347 227 0.017
protein localization to organelle GO:0033365 280 0.017
regulation of actin filament based process GO:0032970 141 0.017
purine ribonucleotide catabolic process GO:0009154 404 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
interferon alpha production GO:0032607 11 0.017
apoptotic mitochondrial changes GO:0008637 57 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
cell fate determination GO:0001709 3 0.017
viral transcription GO:0019083 35 0.017
chromatin assembly GO:0031497 61 0.017
determination of adult lifespan GO:0008340 2 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
regulation of cell migration GO:0030334 289 0.016
gene silencing by rna GO:0031047 26 0.016
production of sirna involved in rna interference GO:0030422 3 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
epithelial cell differentiation GO:0030855 141 0.016
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.016
positive regulation of cell cycle GO:0045787 140 0.016
mrna metabolic process GO:0016071 175 0.016
negative regulation of cell cycle GO:0045786 193 0.015
negative regulation of tumor necrosis factor production GO:0032720 20 0.015
cardiovascular system development GO:0072358 262 0.015
cellular protein complex assembly GO:0043623 188 0.015
positive regulation of response to external stimulus GO:0032103 88 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
regulation of metal ion transport GO:0010959 120 0.015
negative regulation of viral transcription GO:0032897 23 0.015
histone modification GO:0016570 251 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
lipid biosynthetic process GO:0008610 177 0.015
regulation of kinase activity GO:0043549 314 0.015
negative regulation of rig i signaling pathway GO:0039536 2 0.015
signal transduction in response to dna damage GO:0042770 57 0.015
positive regulation of cytoplasmic transport GO:1903651 82 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
interferon gamma production GO:0032609 39 0.014
zymogen activation GO:0031638 70 0.014
response to lipopolysaccharide GO:0032496 70 0.014
regulation of actin filament polymerization GO:0030833 50 0.014
negative regulation of response to external stimulus GO:0032102 83 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
response to oxygen containing compound GO:1901700 369 0.014
regulation of mapk cascade GO:0043408 262 0.014
positive regulation of immune effector process GO:0002699 40 0.014
endocytosis GO:0006897 159 0.014
monosaccharide metabolic process GO:0005996 74 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
leukocyte differentiation GO:0002521 98 0.014
t helper 2 cell cytokine production GO:0035745 3 0.014
cellular response to lipid GO:0071396 127 0.014
regulation of cytokine secretion GO:0050707 57 0.014
negative regulation of protein processing GO:0010955 142 0.014
protein import GO:0017038 130 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
regulation of dna binding GO:0051101 37 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
angiogenesis GO:0001525 147 0.013
protein monoubiquitination GO:0006513 39 0.013
negative regulation of ion transport GO:0043271 39 0.013
protein auto adp ribosylation GO:0070213 4 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
positive regulation of type 2 immune response GO:0002830 2 0.013
circadian behavior GO:0048512 2 0.013
protein catabolic process GO:0030163 325 0.013
stress activated mapk cascade GO:0051403 93 0.013
lipoprotein metabolic process GO:0042157 42 0.013
cellular protein catabolic process GO:0044257 261 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
positive regulation of natural killer cell proliferation GO:0032819 3 0.013
metal ion transport GO:0030001 272 0.013
nucleoside catabolic process GO:0009164 408 0.013
regulation of circadian sleep wake cycle GO:0042749 2 0.013
cellular response to lipopolysaccharide GO:0071222 57 0.013
negative regulation of protein kinase activity GO:0006469 98 0.012
negative regulation of protein modification process GO:0031400 200 0.012
small molecule biosynthetic process GO:0044283 157 0.012
actin polymerization or depolymerization GO:0008154 56 0.012
vasculature development GO:0001944 181 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
actin filament based process GO:0030029 224 0.012
nucleoside diphosphate phosphorylation GO:0006165 12 0.012
plasma membrane organization GO:0007009 115 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
regulation of protein stability GO:0031647 87 0.012
macrophage fusion GO:0034238 1 0.012
regulation of cellular response to stress GO:0080135 244 0.012
type i interferon production GO:0032606 27 0.012
negative regulation of cellular protein catabolic process GO:1903363 38 0.012
positive regulation of secretion GO:0051047 116 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
regulation of cellular component size GO:0032535 82 0.012
protein polymerization GO:0051258 71 0.012
response to lipid GO:0033993 206 0.012
cytokine secretion GO:0050663 64 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
response to tumor necrosis factor GO:0034612 76 0.012
mitotic cell cycle GO:0000278 326 0.012
regulation of anatomical structure size GO:0090066 101 0.012
protein destabilization GO:0031648 12 0.012
autophagy GO:0006914 88 0.012
actin cytoskeleton organization GO:0030036 207 0.012
hematopoietic stem cell differentiation GO:0060218 4 0.012
ribonucleoprotein complex subunit organization GO:0071826 81 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
positive regulation of locomotion GO:0040017 186 0.011
regulation of cellular component movement GO:0051270 334 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
multicellular organismal aging GO:0010259 3 0.011
spermatid development GO:0007286 4 0.011
activation of cysteine type endopeptidase activity GO:0097202 57 0.011
ribonucleoprotein complex biogenesis GO:0022613 116 0.011
protein export from nucleus GO:0006611 29 0.011
negative regulation of immune effector process GO:0002698 38 0.011
lens development in camera type eye GO:0002088 2 0.011
negative regulation of developmental process GO:0051093 247 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
regulation of angiogenesis GO:0045765 92 0.011
cellular amino acid metabolic process GO:0006520 116 0.011
positive regulation of protein import into nucleus GO:0042307 46 0.011
actin nucleation GO:0045010 21 0.011
positive regulation of interleukin 1 beta secretion GO:0050718 11 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.011
covalent chromatin modification GO:0016569 254 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
rna processing GO:0006396 255 0.011
regulation of cell motility GO:2000145 299 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
regulation of protein binding GO:0043393 66 0.010
positive regulation of protein localization to nucleus GO:1900182 48 0.010
protein localization to membrane GO:0072657 160 0.010
regulation of protein maturation GO:1903317 150 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
cell development GO:0048468 328 0.010
cellular response to type i interferon GO:0071357 12 0.010
signal transduction by phosphorylation GO:0023014 297 0.010
divalent inorganic cation transport GO:0072511 158 0.010
spermatid differentiation GO:0048515 4 0.010
positive regulation of protein oligomerization GO:0032461 17 0.010

DDX60 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014