Homo sapiens

9 known processes

LRBA

LPS-responsive vesicle trafficking, beach and anchor containing

(Aliases: CDC4L,DKFZp686A09128,FLJ25686,BGL,LBA,LAB300,MGC72098,DKFZp686K03100,DKFZp686P2258,FLJ16600)

LRBA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleotide catabolic process GO:0009154 404 0.149
nucleoside catabolic process GO:0009164 408 0.122
purine containing compound catabolic process GO:0072523 411 0.109
cellular ketone metabolic process GO:0042180 80 0.105
purine ribonucleoside catabolic process GO:0046130 398 0.091
purine nucleoside catabolic process GO:0006152 398 0.091
ion transmembrane transport GO:0034220 338 0.091
cofactor metabolic process GO:0051186 87 0.090
purine nucleoside monophosphate catabolic process GO:0009128 158 0.087
ras protein signal transduction GO:0007265 73 0.081
post embryonic development GO:0009791 2 0.080
Worm
transmembrane transport GO:0055085 399 0.076
ribonucleoside catabolic process GO:0042454 406 0.073
nucleoside phosphate catabolic process GO:1901292 412 0.073
nucleoside triphosphate metabolic process GO:0009141 422 0.069
purine nucleoside triphosphate catabolic process GO:0009146 392 0.066
purine nucleoside triphosphate metabolic process GO:0009144 412 0.064
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.060
female gamete generation GO:0007292 2 0.058
cellular amino acid metabolic process GO:0006520 116 0.055
nucleoside triphosphate catabolic process GO:0009143 394 0.055
inorganic ion transmembrane transport GO:0098660 231 0.055
oogenesis GO:0048477 2 0.055
rab protein signal transduction GO:0032482 4 0.054
vesicle mediated transport GO:0016192 371 0.053
Worm
actin filament based process GO:0030029 224 0.051
multicellular organismal aging GO:0010259 3 0.050
glycosyl compound catabolic process GO:1901658 413 0.050
organophosphate catabolic process GO:0046434 430 0.049
nucleotide catabolic process GO:0009166 408 0.048
purine nucleotide catabolic process GO:0006195 405 0.048
cell projection organization GO:0030030 252 0.048
small molecule catabolic process GO:0044282 92 0.047
ribonucleoside triphosphate catabolic process GO:0009203 391 0.047
positive regulation of hydrolase activity GO:0051345 331 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.046
ribonucleoside triphosphate metabolic process GO:0009199 412 0.045
positive regulation of cellular component organization GO:0051130 376 0.042
Worm
single organism cellular localization GO:1902580 332 0.042
cellular lipid metabolic process GO:0044255 303 0.041
small gtpase mediated signal transduction GO:0007264 78 0.040
positive regulation of catabolic process GO:0009896 310 0.039
determination of adult lifespan GO:0008340 2 0.038
locomotory behavior GO:0007626 1 0.037
mitochondrion organization GO:0007005 156 0.037
carboxylic acid catabolic process GO:0046395 71 0.036
ribonucleotide catabolic process GO:0009261 405 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
membrane organization GO:0061024 292 0.035
cell morphogenesis GO:0000902 296 0.034
cytoplasmic transport GO:0016482 379 0.034
segmentation GO:0035282 4 0.034
lipid metabolic process GO:0006629 381 0.034
anion transport GO:0006820 161 0.034
actin cytoskeleton organization GO:0030036 207 0.033
endomembrane system organization GO:0010256 196 0.033
system process GO:0003008 349 0.033
Fly
memory GO:0007613 3 0.033
Fly
amine metabolic process GO:0009308 44 0.033
organic acid catabolic process GO:0016054 71 0.032
positive regulation of cellular catabolic process GO:0031331 284 0.031
carbohydrate metabolic process GO:0005975 207 0.031
response to biotic stimulus GO:0009607 276 0.030
oocyte development GO:0048599 1 0.030
cellular component morphogenesis GO:0032989 314 0.030
cellular lipid catabolic process GO:0044242 65 0.030
immune response GO:0006955 307 0.030
regulation of nucleotide metabolic process GO:0006140 269 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
response to oxygen containing compound GO:1901700 369 0.029
purine nucleoside monophosphate metabolic process GO:0009126 186 0.029
cell adhesion GO:0007155 325 0.029
regulation of cell cycle GO:0051726 393 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
blastoderm segmentation GO:0007350 2 0.029
response to abiotic stimulus GO:0009628 336 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
reactive oxygen species biosynthetic process GO:1903409 4 0.028
inorganic cation transmembrane transport GO:0098662 194 0.028
positive regulation of transport GO:0051050 336 0.028
Worm
maintenance of location GO:0051235 112 0.027
cellular response to dna damage stimulus GO:0006974 379 0.027
mitotic cell cycle process GO:1903047 286 0.027
regulation of protein localization GO:0032880 296 0.027
protein localization to plasma membrane GO:0072659 93 0.027
negative regulation of protein metabolic process GO:0051248 391 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
oocyte differentiation GO:0009994 2 0.027
lipid modification GO:0030258 84 0.026
spermatid differentiation GO:0048515 4 0.026
plasma membrane organization GO:0007009 115 0.026
single organism membrane organization GO:0044802 268 0.026
mitotic cell cycle GO:0000278 326 0.026
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
regulation of gtpase activity GO:0043087 180 0.025
defense response GO:0006952 315 0.025
lipid catabolic process GO:0016042 84 0.025
intracellular protein transport GO:0006886 270 0.025
cation transmembrane transport GO:0098655 238 0.025
generation of neurons GO:0048699 152 0.025
Fly
morphogenesis of embryonic epithelium GO:0016331 4 0.025
regulation of dna metabolic process GO:0051052 153 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
positive regulation of organelle organization GO:0010638 195 0.024
negative regulation of organelle organization GO:0010639 126 0.023
hindbrain development GO:0030902 3 0.023
regulation of cell differentiation GO:0045595 393 0.023
positive regulation of gtpase activity GO:0043547 166 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.023
nervous system development GO:0007399 293 0.023
Fly
regulation of homeostatic process GO:0032844 121 0.023
protein processing GO:0016485 226 0.023
monocarboxylic acid metabolic process GO:0032787 185 0.023
biological adhesion GO:0022610 331 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.022
chemical homeostasis GO:0048878 306 0.022
gtp metabolic process GO:0046039 239 0.022
cellular amine metabolic process GO:0044106 41 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
innate immune response GO:0045087 178 0.022
positive regulation of ras gtpase activity GO:0032320 117 0.022
protein maturation GO:0051604 233 0.022
cellular protein complex assembly GO:0043623 188 0.022
neurogenesis GO:0022008 169 0.022
Fly
guanosine containing compound metabolic process GO:1901068 244 0.022
organelle assembly GO:0070925 176 0.022
atp catabolic process GO:0006200 157 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
negative regulation of developmental process GO:0051093 247 0.022
Worm
regulation of cellular ketone metabolic process GO:0010565 50 0.021
secretion by cell GO:0032940 226 0.021
oxidation reduction process GO:0055114 396 0.021
compound eye development GO:0048749 1 0.021
Fly
dna replication GO:0006260 116 0.021
regulation of ras protein signal transduction GO:0046578 155 0.021
anterior posterior axis specification GO:0009948 2 0.021
fatty acid catabolic process GO:0009062 29 0.021
organelle localization GO:0051640 84 0.021
cell part morphogenesis GO:0032990 137 0.021
regulation of ion transport GO:0043269 189 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
secretion GO:0046903 254 0.020
embryo development GO:0009790 123 0.020
actin filament based movement GO:0030048 17 0.020
cell division GO:0051301 168 0.020
regulation of rab protein signal transduction GO:0032483 39 0.020
cell development GO:0048468 328 0.020
Fly
golgi vesicle transport GO:0048193 80 0.020
cardiovascular system development GO:0072358 262 0.020
regulation of cellular component biogenesis GO:0044087 281 0.020
cell projection assembly GO:0030031 126 0.020
apoptotic signaling pathway GO:0097190 268 0.020
metencephalon development GO:0022037 2 0.019
microtubule based process GO:0007017 210 0.019
regulation of cellular component movement GO:0051270 334 0.019
regulation of protein transport GO:0051223 213 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
single organismal cell cell adhesion GO:0016337 148 0.019
meiosis i GO:0007127 4 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
embryonic epithelial tube formation GO:0001838 4 0.019
regulation of cell cycle process GO:0010564 266 0.019
protein localization to membrane GO:0072657 160 0.019
regulation of transferase activity GO:0051338 355 0.019
cell morphogenesis involved in differentiation GO:0000904 144 0.018
response to nitrogen compound GO:1901698 184 0.018
regulation of ion transmembrane transport GO:0034765 132 0.018
cellular homeostasis GO:0019725 196 0.018
endocytosis GO:0006897 159 0.018
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
cell projection morphogenesis GO:0048858 129 0.018
protein targeting GO:0006605 187 0.018
regulation of cellular amino acid metabolic process GO:0006521 6 0.018
adult locomotory behavior GO:0008344 1 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
regulation of vesicle mediated transport GO:0060627 130 0.018
Worm
spermatid development GO:0007286 4 0.018
positive regulation of rab gtpase activity GO:0032851 39 0.018
regulation of rab gtpase activity GO:0032313 39 0.017
response to radiation GO:0009314 151 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
sulfur compound metabolic process GO:0006790 101 0.017
response to external biotic stimulus GO:0043207 261 0.017
neural tube formation GO:0001841 3 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
cell cycle phase transition GO:0044770 173 0.017
anterior posterior axis specification embryo GO:0008595 2 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
metal ion homeostasis GO:0055065 169 0.017
regulation of cell development GO:0060284 161 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
cation transport GO:0006812 331 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
positive regulation of gtp catabolic process GO:0033126 166 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
epithelial cell differentiation GO:0030855 141 0.016
metal ion transport GO:0030001 272 0.016
regulation of peptidase activity GO:0052547 180 0.016
regulation of secretion GO:0051046 194 0.016
ion homeostasis GO:0050801 230 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.015
protein localization to organelle GO:0033365 280 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.015
response to other organism GO:0051707 261 0.015
neuron differentiation GO:0030182 138 0.015
Fly
chromatin modification GO:0016568 298 0.015
regulation of cell migration GO:0030334 289 0.015
circulatory system development GO:0072359 262 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
dephosphorylation GO:0016311 209 0.015
cerebellum development GO:0021549 2 0.015
meiotic chromosome segregation GO:0045132 4 0.015
embryonic placenta development GO:0001892 1 0.015
fatty acid metabolic process GO:0006631 115 0.015
dna repair GO:0006281 198 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
peroxisome organization GO:0007031 28 0.014
glycoprotein metabolic process GO:0009100 110 0.014
actin filament organization GO:0007015 128 0.014
monovalent inorganic cation transport GO:0015672 128 0.014
cell cell signaling GO:0007267 155 0.014
positive regulation of intracellular transport GO:0032388 104 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
cellular chemical homeostasis GO:0055082 180 0.014
regulation of proteolysis GO:0030162 293 0.014
epithelium development GO:0060429 227 0.014
negative regulation of cell cycle GO:0045786 193 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
regulation of cell motility GO:2000145 299 0.014
response to drug GO:0042493 81 0.014
neurological system process GO:0050877 163 0.014
Fly
regulation of mitochondrion organization GO:0010821 54 0.014
inner ear morphogenesis GO:0042472 4 0.014
engulfment of apoptotic cell GO:0043652 2 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
negative regulation of cell death GO:0060548 345 0.014
intracellular protein transmembrane transport GO:0065002 24 0.014
behavior GO:0007610 112 0.014
Fly
gtp catabolic process GO:0006184 237 0.014
lipid biosynthetic process GO:0008610 177 0.013
rna processing GO:0006396 255 0.013
chromosome segregation GO:0007059 114 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
regulation of protein maturation GO:1903317 150 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
response to organonitrogen compound GO:0010243 156 0.013
establishment of organelle localization GO:0051656 59 0.013
positive regulation of protein transport GO:0051222 135 0.013
regulation of secretion by cell GO:1903530 177 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
regulation of dna replication GO:0006275 68 0.013
sequestering of metal ion GO:0051238 24 0.013
rho protein signal transduction GO:0007266 26 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
nuclear division GO:0000280 128 0.012
regulation of protein processing GO:0070613 150 0.012
regulation of organelle assembly GO:1902115 40 0.012
cellular modified amino acid metabolic process GO:0006575 64 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
fatty acid beta oxidation GO:0006635 22 0.012
cation homeostasis GO:0055080 189 0.012
primary neural tube formation GO:0014020 3 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
monocarboxylic acid catabolic process GO:0072329 37 0.012
response to growth factor GO:0070848 205 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
cytokinesis GO:0000910 96 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
regulation of actin filament based process GO:0032970 141 0.012
covalent chromatin modification GO:0016569 254 0.012
receptor metabolic process GO:0043112 81 0.012
tripartite regional subdivision GO:0007351 2 0.012
growth GO:0040007 202 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
intracellular mrna localization GO:0008298 1 0.012
positive regulation of secretion GO:0051047 116 0.012
lipid localization GO:0010876 106 0.011
negative regulation of peptidase activity GO:0010466 91 0.011
response to hormone GO:0009725 175 0.011
long term memory GO:0007616 2 0.011
neuromuscular junction development GO:0007528 3 0.011
Fly
proteasomal protein catabolic process GO:0010498 176 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
single organism reproductive process GO:0044702 98 0.011
cell growth GO:0016049 160 0.011
multi organism cellular process GO:0044764 156 0.011
lipid oxidation GO:0034440 33 0.011
negative regulation of dna metabolic process GO:0051053 57 0.011
cellular cation homeostasis GO:0030003 163 0.011
regulation of intracellular transport GO:0032386 195 0.011
sensory perception GO:0007600 103 0.011
response to wounding GO:0009611 168 0.011
endosomal transport GO:0016197 129 0.011
Worm
regulation of multi organism process GO:0043900 157 0.011
protein homooligomerization GO:0051260 100 0.011
organic hydroxy compound biosynthetic process GO:1901617 71 0.011
coenzyme metabolic process GO:0006732 65 0.011
cell activation GO:0001775 213 0.011
fatty acid oxidation GO:0019395 31 0.011
nerve development GO:0021675 4 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
regulation of canonical wnt signaling pathway GO:0060828 88 0.011
reproductive process GO:0022414 106 0.011
chemotaxis GO:0006935 157 0.011
small molecule biosynthetic process GO:0044283 157 0.011
skeletal system development GO:0001501 79 0.011
long chain fatty acid catabolic process GO:0042758 3 0.011
regulation of cell division GO:0051302 116 0.011
positive regulation of transferase activity GO:0051347 227 0.011
negative regulation of protein processing GO:0010955 142 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.010
establishment of protein localization to peroxisome GO:0072663 15 0.010
regulation of response to external stimulus GO:0032101 222 0.010
wnt signaling pathway GO:0016055 156 0.010
ossification GO:0001503 121 0.010
protein targeting to peroxisome GO:0006625 15 0.010
regulation of cellular response to stress GO:0080135 244 0.010
organelle fission GO:0048285 149 0.010
developmental process involved in reproduction GO:0003006 66 0.010
regulation of kinase activity GO:0043549 314 0.010
nitrogen compound transport GO:0071705 191 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.010
actin mediated cell contraction GO:0070252 12 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
regulation of locomotion GO:0040012 329 0.010
negative regulation of cell differentiation GO:0045596 171 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
neural tube closure GO:0001843 3 0.010
viral process GO:0016032 146 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
regulation of immune response GO:0050776 201 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.010
striated muscle myosin thick filament assembly GO:0071688 2 0.010
anatomical structure homeostasis GO:0060249 100 0.010
peripheral nervous system development GO:0007422 2 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010

LRBA disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.429
inherited metabolic disorder DOID:655 242 0.429
glycogen storage disease DOID:2747 10 0.158
carbohydrate metabolic disorder DOID:2978 55 0.158
glycogen metabolism disorder DOID:0050728 10 0.158
muscular disease DOID:0080000 114 0.024
musculoskeletal system disease DOID:17 223 0.024
muscle tissue disease DOID:66 113 0.024
cardiovascular system disease DOID:1287 106 0.019
myopathy DOID:423 104 0.015
central nervous system disease DOID:331 186 0.012
neurodegenerative disease DOID:1289 102 0.012
nervous system disease DOID:863 431 0.012
disease of cellular proliferation DOID:14566 174 0.012
sensory system disease DOID:0050155 203 0.011
cancer DOID:162 167 0.011
organ system cancer DOID:0050686 164 0.011
immune system disease DOID:2914 155 0.006
hematopoietic system disease DOID:74 100 0.006
primary immunodeficiency disease DOID:612 36 0.003
b cell deficiency DOID:2115 17 0.001
blood protein disease DOID:620 16 0.001
agammaglobulinemia DOID:2583 16 0.001
common variable immunodeficiency DOID:12177 10 0.001