Homo sapiens

0 known processes

PDE12

phosphodiesterase 12

(Aliases: 2'-PDE)

PDE12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.087
multicellular organismal aging GO:0010259 3 0.056
female gamete generation GO:0007292 2 0.053
determination of adult lifespan GO:0008340 2 0.051
amine metabolic process GO:0009308 44 0.050
regulation of cellular amine metabolic process GO:0033238 11 0.046
oogenesis GO:0048477 2 0.046
cellular amino acid metabolic process GO:0006520 116 0.045
organophosphate catabolic process GO:0046434 430 0.045
cellular amine metabolic process GO:0044106 41 0.044
cellular ketone metabolic process GO:0042180 80 0.041
cellular lipid metabolic process GO:0044255 303 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.040
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
regulation of cell cycle GO:0051726 393 0.038
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
nucleoside triphosphate catabolic process GO:0009143 394 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
locomotory behavior GO:0007626 1 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.034
purine nucleotide catabolic process GO:0006195 405 0.033
rna processing GO:0006396 255 0.033
nucleoside catabolic process GO:0009164 408 0.033
lipid metabolic process GO:0006629 381 0.032
purine containing compound catabolic process GO:0072523 411 0.032
ribonucleoside catabolic process GO:0042454 406 0.032
protein catabolic process GO:0030163 325 0.032
ras protein signal transduction GO:0007265 73 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
segmentation GO:0035282 4 0.030
glycosyl compound catabolic process GO:1901658 413 0.030
vesicle mediated transport GO:0016192 371 0.030
small gtpase mediated signal transduction GO:0007264 78 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.030
nervous system development GO:0007399 293 0.029
purine nucleoside catabolic process GO:0006152 398 0.028
cytoplasmic transport GO:0016482 379 0.028
cell development GO:0048468 328 0.027
lipid biosynthetic process GO:0008610 177 0.027
regulation of transferase activity GO:0051338 355 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
protein modification by small protein conjugation GO:0032446 342 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
membrane organization GO:0061024 292 0.024
neuromuscular junction development GO:0007528 3 0.024
positive regulation of programmed cell death GO:0043068 249 0.024
transmembrane transport GO:0055085 399 0.024
system process GO:0003008 349 0.024
cation transport GO:0006812 331 0.024
gtp metabolic process GO:0046039 239 0.024
metal ion transport GO:0030001 272 0.024
cellular macromolecule catabolic process GO:0044265 380 0.023
Human
mitotic cell cycle GO:0000278 326 0.023
single organism cellular localization GO:1902580 332 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
epithelium development GO:0060429 227 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
memory GO:0007613 3 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
guanosine containing compound catabolic process GO:1901069 239 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.022
guanosine containing compound metabolic process GO:1901068 244 0.022
hindbrain development GO:0030902 3 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
regulation of protein kinase activity GO:0045859 289 0.022
cellular component morphogenesis GO:0032989 314 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.021
gtp catabolic process GO:0006184 237 0.021
ncrna metabolic process GO:0034660 108 0.021
cellular response to dna damage stimulus GO:0006974 379 0.021
positive regulation of catabolic process GO:0009896 310 0.021
biological adhesion GO:0022610 331 0.021
regulation of cell cycle process GO:0010564 266 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
cellular protein catabolic process GO:0044257 261 0.021
dephosphorylation GO:0016311 209 0.020
actin filament based process GO:0030029 224 0.020
response to oxygen containing compound GO:1901700 369 0.020
positive regulation of transport GO:0051050 336 0.020
ion homeostasis GO:0050801 230 0.020
regulation of protein localization GO:0032880 296 0.020
single organism membrane organization GO:0044802 268 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
chemical homeostasis GO:0048878 306 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
nitrogen compound transport GO:0071705 191 0.019
regulation of proteolysis GO:0030162 293 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
protein localization to organelle GO:0033365 280 0.019
small molecule biosynthetic process GO:0044283 157 0.019
nucleotide catabolic process GO:0009166 408 0.019
somitogenesis GO:0001756 2 0.019
maintenance of location GO:0051235 112 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.018
intracellular protein transport GO:0006886 270 0.018
ion transmembrane transport GO:0034220 338 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
Human
anion transport GO:0006820 161 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
positive regulation of cell death GO:0010942 263 0.018
secretion GO:0046903 254 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
response to abiotic stimulus GO:0009628 336 0.017
response to cytokine GO:0034097 232 0.017
protein maturation GO:0051604 233 0.017
adult locomotory behavior GO:0008344 1 0.017
mitotic cell cycle process GO:1903047 286 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
cell adhesion GO:0007155 325 0.017
negative regulation of protein modification process GO:0031400 200 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
single organism reproductive process GO:0044702 98 0.017
modification dependent protein catabolic process GO:0019941 209 0.016
regulation of cellular component movement GO:0051270 334 0.016
regulation of kinase activity GO:0043549 314 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
regulation of ras protein signal transduction GO:0046578 155 0.016
mapk cascade GO:0000165 288 0.016
rna interference GO:0016246 4 0.016
endocytosis GO:0006897 159 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
negative regulation of cell cycle GO:0045786 193 0.016
neurogenesis GO:0022008 169 0.016
regulation of mapk cascade GO:0043408 262 0.016
regulation of cell differentiation GO:0045595 393 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
negative regulation of cell death GO:0060548 345 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
cell projection organization GO:0030030 252 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
mitochondrion organization GO:0007005 156 0.016
regulation of cell motility GO:2000145 299 0.016
blastoderm segmentation GO:0007350 2 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
organelle assembly GO:0070925 176 0.016
Human
negative regulation of protein maturation GO:1903318 142 0.016
regulation of protein catabolic process GO:0042176 155 0.016
organic anion transport GO:0015711 103 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
immune response GO:0006955 307 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
regulation of cellular response to stress GO:0080135 244 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
protein processing GO:0016485 226 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
cell morphogenesis GO:0000902 296 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
cation homeostasis GO:0055080 189 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
cation transmembrane transport GO:0098655 238 0.015
ncrna processing GO:0034470 83 0.015
hemopoiesis GO:0030097 180 0.014
rho protein signal transduction GO:0007266 26 0.014
regulation of response to external stimulus GO:0032101 222 0.014
ribonucleoprotein complex biogenesis GO:0022613 116 0.014
Human
protein ubiquitination GO:0016567 314 0.014
response to oxidative stress GO:0006979 121 0.014
response to external biotic stimulus GO:0043207 261 0.014
phospholipid metabolic process GO:0006644 99 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
defense response GO:0006952 315 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
regulation of protein maturation GO:1903317 150 0.014
receptor mediated endocytosis GO:0006898 84 0.014
metal ion homeostasis GO:0055065 169 0.014
secretion by cell GO:0032940 226 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
angiogenesis GO:0001525 147 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
reproductive process GO:0022414 106 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
Human
cytokine production GO:0001816 247 0.013
histone modification GO:0016570 251 0.013
cellular chemical homeostasis GO:0055082 180 0.013
covalent chromatin modification GO:0016569 254 0.013
circulatory system development GO:0072359 262 0.013
response to biotic stimulus GO:0009607 276 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
protein oligomerization GO:0051259 173 0.013
regulation of protein transport GO:0051223 213 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
response to other organism GO:0051707 261 0.013
positive regulation of developmental process GO:0051094 314 0.013
cardiovascular system development GO:0072358 262 0.013
peripheral nervous system development GO:0007422 2 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
cellular homeostasis GO:0019725 196 0.013
cellular protein complex assembly GO:0043623 188 0.013
regeneration GO:0031099 4 0.013
oxidation reduction process GO:0055114 396 0.013
regulation of cell migration GO:0030334 289 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
regulation of cell adhesion GO:0030155 166 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
cell cycle phase transition GO:0044770 173 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
atp metabolic process GO:0046034 176 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
growth GO:0040007 202 0.012
positive regulation of immune system process GO:0002684 283 0.012
myosin filament assembly GO:0031034 2 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
Human
regulation of meiotic cell cycle GO:0051445 4 0.012
microtubule based process GO:0007017 210 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
translation GO:0006412 132 0.012
carbohydrate metabolic process GO:0005975 207 0.012
actin filament based movement GO:0030048 17 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
regulation of intracellular transport GO:0032386 195 0.012
chromatin modification GO:0016568 298 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
protein homooligomerization GO:0051260 100 0.012
coenzyme metabolic process GO:0006732 65 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
associative learning GO:0008306 1 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
protein localization to membrane GO:0072657 160 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
vesicle targeting rough er to cis golgi GO:0048207 2 0.012
tripartite regional subdivision GO:0007351 2 0.012
apoptotic signaling pathway GO:0097190 268 0.012
positive regulation of cell cycle GO:0045787 140 0.012
oocyte development GO:0048599 1 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
methylation GO:0032259 106 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
actin cytoskeleton organization GO:0030036 207 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
embryo development GO:0009790 123 0.012
nuclear transport GO:0051169 179 0.012
innate immune response GO:0045087 178 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
organelle localization GO:0051640 84 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.011
response to organic cyclic compound GO:0014070 204 0.011
mitotic sister chromatid segregation GO:0000070 53 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
myeloid cell differentiation GO:0030099 117 0.011
protein acylation GO:0043543 138 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
cell fate determination GO:0001709 3 0.011
vasculature development GO:0001944 181 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of cytokine production GO:0001817 232 0.011
chromatin organization GO:0006325 351 0.011
myosin filament organization GO:0031033 2 0.011
generation of neurons GO:0048699 152 0.011
regulation of immune response GO:0050776 201 0.011
protein targeting GO:0006605 187 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
rna splicing GO:0008380 131 0.011
actin mediated cell contraction GO:0070252 12 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
blood vessel morphogenesis GO:0048514 162 0.011
developmental process involved in reproduction GO:0003006 66 0.011
positive regulation of immune response GO:0050778 159 0.011
spermatid differentiation GO:0048515 4 0.011
visual behavior GO:0007632 2 0.011
neurological system process GO:0050877 163 0.011
nuclear division GO:0000280 128 0.011
divalent inorganic cation transport GO:0072511 158 0.011
alcohol metabolic process GO:0006066 114 0.011
organelle fission GO:0048285 149 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
regulation of protein processing GO:0070613 150 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
positive regulation of cytokine production GO:0001819 167 0.011
regulation of multi organism process GO:0043900 157 0.011
cellular cation homeostasis GO:0030003 163 0.011
glycerophospholipid metabolic process GO:0006650 84 0.011
blood vessel development GO:0001568 172 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
divalent metal ion transport GO:0070838 152 0.011
meiotic chromosome segregation GO:0045132 4 0.011
organic acid biosynthetic process GO:0016053 97 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
meiosis i GO:0007127 4 0.011
negative regulation of protein processing GO:0010955 142 0.011
negative regulation of transferase activity GO:0051348 124 0.011
anterior posterior axis specification embryo GO:0008595 2 0.010
immune system development GO:0002520 195 0.010
photoreceptor cell differentiation GO:0046530 2 0.010
cell part morphogenesis GO:0032990 137 0.010
negative regulation of proteolysis GO:0045861 132 0.010
sulfur compound metabolic process GO:0006790 101 0.010
single organism cell adhesion GO:0098602 179 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
regulation of vasculature development GO:1901342 97 0.010
response to lipid GO:0033993 206 0.010
long term memory GO:0007616 2 0.010
protein deubiquitination GO:0016579 79 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
glycerolipid metabolic process GO:0046486 107 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
maturation of ssu rrna GO:0030490 3 0.010
regulation of secretion by cell GO:1903530 177 0.010
cofactor metabolic process GO:0051186 87 0.010
response to radiation GO:0009314 151 0.010
regulation of ion transport GO:0043269 189 0.010
response to axon injury GO:0048678 1 0.010
neural tube formation GO:0001841 3 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
limbic system development GO:0021761 3 0.010
positive regulation of gliogenesis GO:0014015 4 0.010
regulation of dna metabolic process GO:0051052 153 0.010

PDE12 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
disease of metabolism DOID:0014667 295 0.027
inherited metabolic disorder DOID:655 242 0.022
eye and adnexa disease DOID:1492 150 0.019
eye disease DOID:5614 149 0.019
immune system disease DOID:2914 155 0.018
musculoskeletal system disease DOID:17 223 0.018
disease of cellular proliferation DOID:14566 174 0.016
cancer DOID:162 167 0.014
organ system cancer DOID:0050686 164 0.014
connective tissue disease DOID:65 109 0.013
hematopoietic system disease DOID:74 100 0.012
retinal disease DOID:5679 118 0.011
retinal degeneration DOID:8466 89 0.011
central nervous system disease DOID:331 186 0.011