|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
16 |
1.000
|
|
|
|
regulation of atrial cardiac muscle cell membrane repolarization
|
GO:0060372 |
4 |
1.000
|
Human |
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
1.000
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.998
|
Human Rat Fly |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.979
|
Human Rat Fly |
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
1 |
0.971
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.962
|
Human Rat Fly |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.959
|
Human Rat |
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.959
|
Human Rat |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.951
|
Human Rat |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.949
|
Human Rat |
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.944
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.942
|
Human Rat Fly |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.932
|
Fly |
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
1 |
0.909
|
|
|
|
potassium ion export
|
GO:0071435 |
9 |
0.904
|
Human |
|
|
startle response
|
GO:0001964 |
3 |
0.892
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.891
|
Human Rat Fly |
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.887
|
|
|
|
system process
|
GO:0003008 |
349 |
0.873
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.863
|
Human Fly |
|
|
associative learning
|
GO:0008306 |
1 |
0.858
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.857
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.835
|
Human Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.823
|
Human Rat Fly |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.806
|
Human Rat |
|
|
action potential
|
GO:0001508 |
34 |
0.806
|
Human Fly |
|
|
cardiac muscle cell action potential involved in contraction
|
GO:0086002 |
21 |
0.795
|
Human |
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.788
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.781
|
Fly |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.776
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.766
|
Fly |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.762
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.743
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.732
|
Fly |
|
|
mating
|
GO:0007618 |
1 |
0.719
|
Fly |
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.705
|
Human |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.700
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.694
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.681
|
Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.680
|
Human Rat Fly |
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.662
|
Fly |
|
|
directional locomotion
|
GO:0033058 |
1 |
0.646
|
|
|
|
receptor localization to synapse
|
GO:0097120 |
1 |
0.643
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.592
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.568
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.558
|
Fly |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.546
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.541
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.539
|
Human |
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.537
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.529
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.528
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.514
|
Fly |
|
|
dimeric g protein coupled receptor signaling pathway
|
GO:0038042 |
1 |
0.514
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.512
|
Human Rat |
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.501
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.494
|
Human |
|
|
vocalization behavior
|
GO:0071625 |
11 |
0.492
|
|
|
|
positive regulation of membrane potential
|
GO:0045838 |
2 |
0.481
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.474
|
Human Rat |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.471
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.456
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.446
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.438
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.430
|
|
|
|
regulation of sensory perception of pain
|
GO:0051930 |
3 |
0.424
|
|
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.408
|
Human |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.398
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.394
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.392
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.391
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.390
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.387
|
Human |
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.383
|
Fly |
|
|
membrane hyperpolarization
|
GO:0060081 |
1 |
0.375
|
Human |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.374
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.372
|
Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.371
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.364
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.361
|
Human |
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.356
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.356
|
|
|
|
protein localization to synapse
|
GO:0035418 |
2 |
0.354
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.353
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.350
|
|
|
|
fear response
|
GO:0042596 |
0 |
0.342
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.339
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.339
|
Fly |
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.338
|
Human |
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.328
|
Human |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.326
|
|
|
|
memory
|
GO:0007613 |
3 |
0.316
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.312
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.311
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.310
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.309
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.309
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.305
|
Fly |
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.302
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.302
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.301
|
|
|
|
negative regulation of transmission of nerve impulse
|
GO:0051970 |
1 |
0.300
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.298
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.297
|
Fly |
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.290
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.285
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.278
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.272
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.270
|
Human |
|
|
neuron development
|
GO:0048666 |
113 |
0.266
|
Fly |
|
|
potassium ion import
|
GO:0010107 |
9 |
0.266
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.260
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.257
|
Human |
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.250
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.245
|
|
|
|
regulation of transmission of nerve impulse
|
GO:0051969 |
2 |
0.243
|
|
|
|
cellular response to manganese ion
|
GO:0071287 |
1 |
0.243
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.241
|
|
|
|
regulation of sensory perception
|
GO:0051931 |
3 |
0.240
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
0.240
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.239
|
Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.237
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.235
|
|
|
|
regulation of heart rate by cardiac conduction
|
GO:0086091 |
19 |
0.229
|
Human |
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.227
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.224
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.220
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.219
|
Fly |
|
|
regulation of actin filament based movement
|
GO:1903115 |
24 |
0.219
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.214
|
|
|
|
growth
|
GO:0040007 |
202 |
0.214
|
Fly |
|
|
head development
|
GO:0060322 |
108 |
0.213
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
7 |
0.210
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.206
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.202
|
Human |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.201
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.201
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.199
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.198
|
Fly |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.197
|
|
|
|
regulation of acrosome reaction
|
GO:0060046 |
4 |
0.196
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.190
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.188
|
|
|
|
neuromuscular process
|
GO:0050905 |
15 |
0.188
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
15 |
0.186
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.184
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.181
|
Fly |
|
|
cell communication involved in cardiac conduction
|
GO:0086065 |
18 |
0.179
|
Human |
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.179
|
Human |
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.178
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.177
|
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.174
|
|
|
|
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway
|
GO:0007196 |
4 |
0.171
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.166
|
|
|
|
response to manganese ion
|
GO:0010042 |
2 |
0.164
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.163
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.162
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.160
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.158
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.156
|
Human |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.154
|
|
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
1 |
0.148
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.144
|
|
|
|
positive regulation of acrosome reaction
|
GO:2000344 |
4 |
0.144
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.143
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.141
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.140
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.137
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.136
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.134
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.134
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.133
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.132
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.132
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.127
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.126
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.126
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.125
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.122
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.122
|
|
|
|
indole containing compound metabolic process
|
GO:0042430 |
4 |
0.120
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.120
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.117
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.116
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.116
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.112
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.112
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.111
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.111
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.111
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.110
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.110
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.108
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.108
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.107
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.106
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.104
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.102
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.101
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.099
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.097
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.097
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.096
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.095
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.094
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.093
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.093
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.092
|
|
|
|
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering
|
GO:0097113 |
1 |
0.092
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.092
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.092
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.090
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.090
|
|
|
|
detection of visible light
|
GO:0009584 |
11 |
0.090
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.089
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.088
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.088
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.087
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.087
|
Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.086
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.084
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.083
|
|
|
|
adult behavior
|
GO:0030534 |
18 |
0.083
|
Fly |
|
|
phospholipase c activating adrenergic receptor signaling pathway
|
GO:0071882 |
1 |
0.082
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.082
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.082
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.081
|
|
|
|
negative regulation of receptor mediated endocytosis
|
GO:0048261 |
6 |
0.081
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.080
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.078
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.078
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.078
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.078
|
|
|
|
receptor clustering
|
GO:0043113 |
9 |
0.078
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.077
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.077
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.077
|
Human |
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.076
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.074
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.074
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.073
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.073
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.073
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.073
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.072
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.072
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.072
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.071
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.071
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.071
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.070
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.070
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.070
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.070
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.070
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.069
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.069
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.068
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.068
|
Fly |
|
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.068
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.068
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.067
|
|
|
|
membrane depolarization
|
GO:0051899 |
26 |
0.067
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.067
|
Fly |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.067
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.067
|
|
|
|
behavioral fear response
|
GO:0001662 |
0 |
0.067
|
|
|
|
activation of mapk activity by adrenergic receptor signaling pathway
|
GO:0071883 |
3 |
0.066
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.066
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.066
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.065
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.065
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.065
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.064
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.064
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.064
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.064
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.064
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.063
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.063
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.063
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.063
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.062
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.062
|
|
|
|
cellular response to histamine
|
GO:0071420 |
3 |
0.062
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.062
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.062
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.061
|
|
|
|
response to dsrna
|
GO:0043331 |
25 |
0.061
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.061
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.060
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.060
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.060
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.059
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.059
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.058
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.058
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.058
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.058
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.058
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.057
|
Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.057
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.057
|
|
|
|
presynaptic membrane organization
|
GO:0097090 |
3 |
0.056
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.056
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.056
|
|
|
|
atrial cardiac muscle cell to av node cell communication
|
GO:0086066 |
6 |
0.056
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.056
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
2 |
0.055
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.055
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.055
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.055
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.055
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.055
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.054
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.054
|
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
43 |
0.054
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.054
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.054
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.054
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.054
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.053
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.053
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.053
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.053
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.052
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.052
|
|
|
|
gamma aminobutyric acid signaling pathway
|
GO:0007214 |
3 |
0.052
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.050
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.050
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.050
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
6 |
0.049
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.049
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.049
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.049
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.048
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
6 |
0.048
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.048
|
Human |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.048
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.048
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.048
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.047
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
11 |
0.047
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.047
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.047
|
Human |
|
|
positive regulation of heart growth
|
GO:0060421 |
2 |
0.046
|
|
|
|
positive regulation of synaptic vesicle transport
|
GO:1902805 |
1 |
0.046
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.046
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.046
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.046
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.046
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.045
|
Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.045
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.045
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.045
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.045
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.044
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.044
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.044
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.044
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.044
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.044
|
|
|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
0.043
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.043
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.043
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.043
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.043
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.043
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.042
|
|
|
|
response to ethanol
|
GO:0045471 |
11 |
0.042
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.042
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.041
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.041
|
|
|
|
detection of light stimulus
|
GO:0009583 |
11 |
0.041
|
Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.041
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.041
|
Fly |
|
|
neuron cell cell adhesion
|
GO:0007158 |
1 |
0.041
|
|
|
|
cerebral cortex development
|
GO:0021987 |
10 |
0.040
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.040
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.040
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.040
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.040
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.040
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.040
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.040
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.039
|
|
|
|
cellular response to epinephrine stimulus
|
GO:0071872 |
2 |
0.039
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.039
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.039
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.039
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.039
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.039
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.039
|
|
|
|
detection of chemical stimulus involved in sensory perception of smell
|
GO:0050911 |
2 |
0.038
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.038
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.038
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.038
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.038
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.038
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.038
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.037
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.037
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.037
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.037
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.037
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.037
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.037
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.037
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.037
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.037
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.036
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.036
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.035
|
Fly |
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.035
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.035
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.035
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.035
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.035
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.034
|
|
|
|
response to magnesium ion
|
GO:0032026 |
3 |
0.034
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.034
|
|
|
|
negative regulation of endothelial cell development
|
GO:1901551 |
1 |
0.034
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.034
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.034
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.034
|
Fly |
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.033
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.033
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.033
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.033
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.033
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.033
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.033
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.032
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.032
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.032
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.032
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.032
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.032
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.032
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.032
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.032
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.032
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.032
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.031
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.031
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.031
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.031
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.031
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.031
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.030
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.030
|
|
|
|
chemical homeostasis within a tissue
|
GO:0048875 |
3 |
0.030
|
|
|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.030
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.030
|
Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.030
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.030
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.030
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.030
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.030
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.030
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.029
|
Fly |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.029
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.029
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.029
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.029
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.029
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.029
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.029
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.029
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.029
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.029
|
Fly |
|
|
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
|
GO:0044338 |
2 |
0.029
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.029
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.029
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.029
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.029
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.029
|
|
|
|
dendritic spine organization
|
GO:0097061 |
4 |
0.028
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.028
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.028
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.028
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.028
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.028
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.028
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.028
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.028
|
|
