Homo sapiens

48 known processes

FTO

fat mass and obesity associated

(Aliases: KIAA1752,MGC5149)

FTO biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.064
cellular amino acid metabolic process GO:0006520 116 0.060
ras protein signal transduction GO:0007265 73 0.058
regulation of cellular amino acid metabolic process GO:0006521 6 0.053
cellular ketone metabolic process GO:0042180 80 0.051
cellular amine metabolic process GO:0044106 41 0.051
regulation of cellular amine metabolic process GO:0033238 11 0.047
regulation of cellular ketone metabolic process GO:0010565 50 0.046
segmentation GO:0035282 4 0.043
associative learning GO:0008306 1 0.037
oogenesis GO:0048477 2 0.036
nervous system development GO:0007399 293 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
locomotory behavior GO:0007626 1 0.033
amine metabolic process GO:0009308 44 0.033
memory GO:0007613 3 0.032
multicellular organismal aging GO:0010259 3 0.032
female gamete generation GO:0007292 2 0.031
cytoplasmic transport GO:0016482 379 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
glycosyl compound catabolic process GO:1901658 413 0.029
cellular macromolecule catabolic process GO:0044265 380 0.029
single organism cellular localization GO:1902580 332 0.029
blastoderm segmentation GO:0007350 2 0.029
oxidation reduction process GO:0055114 396 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
vesicle mediated transport GO:0016192 371 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
determination of adult lifespan GO:0008340 2 0.027
system process GO:0003008 349 0.026
response to abiotic stimulus GO:0009628 336 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
protein catabolic process GO:0030163 325 0.026
organophosphate catabolic process GO:0046434 430 0.026
small gtpase mediated signal transduction GO:0007264 78 0.025
cell projection organization GO:0030030 252 0.025
nucleoside triphosphate metabolic process GO:0009141 422 0.025
nucleoside triphosphate catabolic process GO:0009143 394 0.025
cellular component morphogenesis GO:0032989 314 0.025
protein modification by small protein conjugation GO:0032446 342 0.025
cell morphogenesis GO:0000902 296 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
regulation of locomotion GO:0040012 329 0.024
anterior posterior axis specification embryo GO:0008595 2 0.024
purine containing compound catabolic process GO:0072523 411 0.023
regulation of cell differentiation GO:0045595 393 0.023
regulation of cellular component movement GO:0051270 334 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.022
oocyte differentiation GO:0009994 2 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
nucleotide catabolic process GO:0009166 408 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
positive regulation of catabolic process GO:0009896 310 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
protein localization to organelle GO:0033365 280 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
anterior posterior axis specification GO:0009948 2 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
cellular response to endogenous stimulus GO:0071495 336 0.021
neurological system process GO:0050877 163 0.021
protein processing GO:0016485 226 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
protein maturation GO:0051604 233 0.020
positive regulation of cellular amine metabolic process GO:0033240 7 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.020
regeneration GO:0031099 4 0.020
response to oxygen containing compound GO:1901700 369 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
regulation of cell cycle GO:0051726 393 0.020
oocyte development GO:0048599 1 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
cardiac muscle cell contraction GO:0086003 4 0.019
biological adhesion GO:0022610 331 0.019
neuromuscular junction development GO:0007528 3 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
immune response GO:0006955 307 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
microtubule based process GO:0007017 210 0.019
rho protein signal transduction GO:0007266 26 0.019
actin filament based process GO:0030029 224 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
small molecule catabolic process GO:0044282 92 0.018
cellular lipid metabolic process GO:0044255 303 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.018
ion transmembrane transport GO:0034220 338 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
cell adhesion GO:0007155 325 0.018
cation transmembrane transport GO:0098655 238 0.018
tripartite regional subdivision GO:0007351 2 0.018
mitotic cell cycle GO:0000278 326 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
secretion by cell GO:0032940 226 0.017
regulation of kinase activity GO:0043549 314 0.017
regulation of transferase activity GO:0051338 355 0.017
regulation of proteolysis GO:0030162 293 0.017
adult locomotory behavior GO:0008344 1 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
regulation of protein localization GO:0032880 296 0.017
dephosphorylation GO:0016311 209 0.017
gtp metabolic process GO:0046039 239 0.017
apoptotic signaling pathway GO:0097190 268 0.017
positive regulation of transport GO:0051050 336 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
cellular protein catabolic process GO:0044257 261 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
secretion GO:0046903 254 0.017
rhythmic behavior GO:0007622 2 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
metencephalon development GO:0022037 2 0.017
endocytosis GO:0006897 159 0.017
protein ubiquitination GO:0016567 314 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
chemical homeostasis GO:0048878 306 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
neurotransmitter secretion GO:0007269 4 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
mitotic cell cycle process GO:1903047 286 0.016
nucleoside catabolic process GO:0009164 408 0.016
regulation of cellular response to stress GO:0080135 244 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
response to external biotic stimulus GO:0043207 261 0.016
chromatin organization GO:0006325 351 0.016
protein oligomerization GO:0051259 173 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.016
defense response GO:0006952 315 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
maintenance of location GO:0051235 112 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
gtp catabolic process GO:0006184 237 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
actin filament based movement GO:0030048 17 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
circadian behavior GO:0048512 2 0.016
negative regulation of cell proliferation GO:0008285 228 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
hindbrain development GO:0030902 3 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
cerebellum development GO:0021549 2 0.015
sleep GO:0030431 2 0.015
ion homeostasis GO:0050801 230 0.015
peripheral nervous system development GO:0007422 2 0.015
atp metabolic process GO:0046034 176 0.015
actin mediated cell contraction GO:0070252 12 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
transmembrane transport GO:0055085 399 0.015
mapk cascade GO:0000165 288 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
regulation of protein kinase activity GO:0045859 289 0.015
regulation of cell motility GO:2000145 299 0.015
striated muscle contraction GO:0006941 52 0.015
regulation of cell migration GO:0030334 289 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
cell division GO:0051301 168 0.015
membrane organization GO:0061024 292 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
regulation of secretion by cell GO:1903530 177 0.014
single organism membrane organization GO:0044802 268 0.014
regulation of protein processing GO:0070613 150 0.014
positive regulation of immune system process GO:0002684 283 0.014
histone modification GO:0016570 251 0.014
cellular chemical homeostasis GO:0055082 180 0.014
regulation of protein maturation GO:1903317 150 0.014
cell cycle phase transition GO:0044770 173 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
neural tube formation GO:0001841 3 0.014
tissue migration GO:0090130 119 0.014
regulation of neurotransmitter secretion GO:0046928 3 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
regulation of protein catabolic process GO:0042176 155 0.014
primary neural tube formation GO:0014020 3 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
cellular homeostasis GO:0019725 196 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
spermatid differentiation GO:0048515 4 0.014
nitrogen compound transport GO:0071705 191 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
response to axon injury GO:0048678 1 0.014
negative regulation of protein modification process GO:0031400 200 0.013
chromosome segregation GO:0007059 114 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
regulation of mapk cascade GO:0043408 262 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
lipid metabolic process GO:0006629 381 0.013
axon cargo transport GO:0008088 2 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
negative regulation of cell death GO:0060548 345 0.013
regulation of secretion GO:0051046 194 0.013
compound eye development GO:0048749 1 0.013
negative regulation of protein processing GO:0010955 142 0.013
protein localization to membrane GO:0072657 160 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
lipid biosynthetic process GO:0008610 177 0.013
positive regulation of developmental process GO:0051094 314 0.013
response to biotic stimulus GO:0009607 276 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
intracellular protein transport GO:0006886 270 0.013
response to other organism GO:0051707 261 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
single organismal cell cell adhesion GO:0016337 148 0.013
mating GO:0007618 1 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
chromatin modification GO:0016568 298 0.013
innate immune response GO:0045087 178 0.013
inner ear morphogenesis GO:0042472 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
endomembrane system organization GO:0010256 196 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
regulation of transporter activity GO:0032409 82 0.013
cell projection assembly GO:0030031 126 0.012
organ formation GO:0048645 3 0.012
retinal ganglion cell axon guidance GO:0031290 2 0.012
negative regulation of cell cycle GO:0045786 193 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
cell part morphogenesis GO:0032990 137 0.012
neuron projection regeneration GO:0031102 1 0.012
negative regulation of developmental process GO:0051093 247 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
motor neuron axon guidance GO:0008045 2 0.012
negative regulation of protein maturation GO:1903318 142 0.012
regulation of cell adhesion GO:0030155 166 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
regulation of multi organism process GO:0043900 157 0.012
cofactor metabolic process GO:0051186 87 0.012
plasma membrane organization GO:0007009 115 0.012
cell development GO:0048468 328 0.012
regulation of cell development GO:0060284 161 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
positive regulation of cell death GO:0010942 263 0.012
axon regeneration GO:0031103 1 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
regulation of dna metabolic process GO:0051052 153 0.012
taxis GO:0042330 157 0.012
neuroblast proliferation GO:0007405 4 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
organelle assembly GO:0070925 176 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
regulation of ion transport GO:0043269 189 0.012
negative regulation of organelle organization GO:0010639 126 0.012
regulation of cell cycle process GO:0010564 266 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
sex determination GO:0007530 3 0.012
salivary gland morphogenesis GO:0007435 4 0.012
epithelium migration GO:0090132 119 0.012
neuron development GO:0048666 113 0.012
cellular protein complex assembly GO:0043623 188 0.012
epithelial cell proliferation GO:0050673 128 0.012
metal ion homeostasis GO:0055065 169 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
response to radiation GO:0009314 151 0.011
cation transport GO:0006812 331 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
nuclear migration GO:0007097 1 0.011
organelle fission GO:0048285 149 0.011
cilium morphogenesis GO:0060271 75 0.011
spinal cord development GO:0021510 4 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.011
cell projection morphogenesis GO:0048858 129 0.011
nuclear transport GO:0051169 179 0.011
regulation of ion transmembrane transport GO:0034765 132 0.011
regulation of intracellular transport GO:0032386 195 0.011
somatic muscle development GO:0007525 1 0.011
long term memory GO:0007616 2 0.011
response to nitrogen compound GO:1901698 184 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
regulation of gtpase activity GO:0043087 180 0.011
actin cytoskeleton organization GO:0030036 207 0.011
sequestering of calcium ion GO:0051208 17 0.011
regulation of protein transport GO:0051223 213 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.011
metal ion transport GO:0030001 272 0.011
muscle system process GO:0003012 81 0.011
protein targeting GO:0006605 187 0.011
sensory perception of pain GO:0019233 4 0.011
circulatory system development GO:0072359 262 0.011
rna interference GO:0016246 4 0.011
cilium assembly GO:0042384 63 0.011
regulation of feeding behavior GO:0060259 3 0.011
neuron projection development GO:0031175 106 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
glycerolipid metabolic process GO:0046486 107 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
cell cycle checkpoint GO:0000075 117 0.011
positive regulation of mesonephros development GO:0061213 2 0.011
negative regulation of smoothened signaling pathway GO:0045879 3 0.011
nerve development GO:0021675 4 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
protein acylation GO:0043543 138 0.011
regulation of immune response GO:0050776 201 0.011
visual behavior GO:0007632 2 0.011
epithelium development GO:0060429 227 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
divalent inorganic cation transport GO:0072511 158 0.011
convergent extension GO:0060026 1 0.011
calcium ion transmembrane transport GO:0070588 76 0.011
regulation of homeostatic process GO:0032844 121 0.011
divalent metal ion transport GO:0070838 152 0.011
meiotic chromosome segregation GO:0045132 4 0.011
anion transport GO:0006820 161 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
response to fungus GO:0009620 4 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
tube closure GO:0060606 3 0.011
blood circulation GO:0008015 113 0.011
dna repair GO:0006281 198 0.011
response to inorganic substance GO:0010035 127 0.011
response to wounding GO:0009611 168 0.011
regulation of metal ion transport GO:0010959 120 0.010
covalent chromatin modification GO:0016569 254 0.010
glycerophospholipid metabolic process GO:0006650 84 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
positive regulation of transferase activity GO:0051347 227 0.010
ameboidal type cell migration GO:0001667 135 0.010
organic acid catabolic process GO:0016054 71 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
carbohydrate metabolic process GO:0005975 207 0.010
negative regulation of blood pressure GO:0045776 3 0.010
spermatid development GO:0007286 4 0.010
cellular cation homeostasis GO:0030003 163 0.010
cell substrate adhesion GO:0031589 132 0.010
epithelial cell migration GO:0010631 119 0.010
cell growth GO:0016049 160 0.010
nucleus localization GO:0051647 1 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
regulation of actin filament based process GO:0032970 141 0.010
immune system development GO:0002520 195 0.010
calcium ion transport GO:0006816 147 0.010
neuron differentiation GO:0030182 138 0.010
coenzyme metabolic process GO:0006732 65 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
negative regulation of cell differentiation GO:0045596 171 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
regulation of glial cell differentiation GO:0045685 3 0.010
negative regulation of locomotion GO:0040013 118 0.010
generation of neurons GO:0048699 152 0.010
peptidyl lysine modification GO:0018205 144 0.010
cellular ion homeostasis GO:0006873 168 0.010

FTO disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.089
inherited metabolic disorder DOID:655 242 0.064
glycogen storage disease DOID:2747 10 0.055
carbohydrate metabolic disorder DOID:2978 55 0.055
glycogen metabolism disorder DOID:0050728 10 0.055
central nervous system disease DOID:331 186 0.035
nervous system disease DOID:863 431 0.035
musculoskeletal system disease DOID:17 223 0.027
neurodegenerative disease DOID:1289 102 0.026
sensory system disease DOID:0050155 203 0.018
cardiovascular system disease DOID:1287 106 0.018
connective tissue disease DOID:65 109 0.017
immune system disease DOID:2914 155 0.016
myopathy DOID:423 104 0.015
muscular disease DOID:0080000 114 0.015
muscle tissue disease DOID:66 113 0.015
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
bone disease DOID:0080001 88 0.013
hematopoietic system disease DOID:74 100 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
brain disease DOID:936 73 0.011
retinal disease DOID:5679 118 0.010