Homo sapiens

21 known processes

TNK1

tyrosine kinase, non-receptor, 1

(Aliases: MGC46193)

TNK1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cloacal septation GO:0060197 1 0.185
ribonucleoside catabolic process GO:0042454 406 0.127
nucleoside triphosphate metabolic process GO:0009141 422 0.121
ribonucleoside triphosphate metabolic process GO:0009199 412 0.111
purine nucleotide catabolic process GO:0006195 405 0.107
purine nucleoside triphosphate metabolic process GO:0009144 412 0.104
mesonephric duct development GO:0072177 3 0.099
small gtpase mediated signal transduction GO:0007264 78 0.097
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.090
guanosine containing compound metabolic process GO:1901068 244 0.082
purine containing compound catabolic process GO:0072523 411 0.082
gtp metabolic process GO:0046039 239 0.077
nucleoside phosphate catabolic process GO:1901292 412 0.076
segmentation GO:0035282 4 0.073
actin filament based process GO:0030029 224 0.072
Human
epithelium development GO:0060429 227 0.072
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.071
positive regulation of cortisol biosynthetic process GO:2000066 1 0.066
cellular ketone metabolic process GO:0042180 80 0.062
organophosphate catabolic process GO:0046434 430 0.062
nucleotide catabolic process GO:0009166 408 0.062
system process GO:0003008 349 0.061
glycosyl compound catabolic process GO:1901658 413 0.061
purine nucleoside catabolic process GO:0006152 398 0.061
rho protein signal transduction GO:0007266 26 0.060
regulation of purine nucleotide metabolic process GO:1900542 264 0.059
blastoderm segmentation GO:0007350 2 0.057
purine ribonucleoside catabolic process GO:0046130 398 0.057
purine ribonucleoside metabolic process GO:0046128 437 0.053
gtp catabolic process GO:0006184 237 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.051
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.050
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.050
regulation of purine nucleotide catabolic process GO:0033121 205 0.050
regulation of gtp catabolic process GO:0033124 180 0.048
guanosine containing compound catabolic process GO:1901069 239 0.048
regulation of nucleotide catabolic process GO:0030811 205 0.048
positive regulation of cellular catabolic process GO:0031331 284 0.047
ras protein signal transduction GO:0007265 73 0.047
Mouse
regulation of ras protein signal transduction GO:0046578 155 0.046
Mouse
purine ribonucleotide catabolic process GO:0009154 404 0.045
regulation of dermatome development GO:0061183 3 0.044
lipid biosynthetic process GO:0008610 177 0.044
positive regulation of gtpase activity GO:0043547 166 0.044
nucleoside catabolic process GO:0009164 408 0.043
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.043
epithelial cell differentiation GO:0030855 141 0.042
ribonucleotide catabolic process GO:0009261 405 0.041
nucleoside triphosphate catabolic process GO:0009143 394 0.040
post embryonic development GO:0009791 2 0.039
regulation of cellular ketone metabolic process GO:0010565 50 0.039
regulation of gtpase activity GO:0043087 180 0.039
anterior posterior axis specification GO:0009948 2 0.038
regulation of nucleoside metabolic process GO:0009118 209 0.037
membrane organization GO:0061024 292 0.036
negative regulation of testosterone biosynthetic process GO:2000225 1 0.036
regulation of nucleotide metabolic process GO:0006140 269 0.036
single organism membrane organization GO:0044802 268 0.035
regulation of cellular component biogenesis GO:0044087 281 0.035
Human
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.035
cellular lipid metabolic process GO:0044255 303 0.034
negative regulation of testicular blood vessel morphogenesis GO:0061369 1 0.033
positive regulation of transport GO:0051050 336 0.033
cardiac muscle cell contraction GO:0086003 4 0.033
enzyme linked receptor protein signaling pathway GO:0007167 303 0.032
Human
lipid metabolic process GO:0006629 381 0.032
positive regulation of nucleoside metabolic process GO:0045979 186 0.032
single organism cellular localization GO:1902580 332 0.031
positive regulation of ras gtpase activity GO:0032320 117 0.030
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.030
follicle stimulating hormone secretion GO:0046884 3 0.030
endomembrane system organization GO:0010256 196 0.030
cell development GO:0048468 328 0.029
Human Fly
establishment of protein localization to membrane GO:0090150 121 0.029
negative regulation of male gonad development GO:2000019 1 0.029
wnt signaling pathway GO:0016055 156 0.028
cellular response to endogenous stimulus GO:0071495 336 0.027
Human
pulmonary valve formation GO:0003193 1 0.027
protein localization to membrane GO:0072657 160 0.027
positive regulation of catabolic process GO:0009896 310 0.026
positive regulation of aldosterone metabolic process GO:0032346 2 0.026
nervous system development GO:0007399 293 0.026
Human
regulation of ras gtpase activity GO:0032318 128 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
epidermis morphogenesis GO:0048730 3 0.026
multicellular organismal aging GO:0010259 3 0.026
chemical homeostasis GO:0048878 306 0.026
positive regulation of nucleotide catabolic process GO:0030813 185 0.026
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
determination of adult lifespan GO:0008340 2 0.025
protein localization to plasma membrane GO:0072659 93 0.025
anterior posterior axis specification embryo GO:0008595 2 0.025
regulation of mapk cascade GO:0043408 262 0.025
Human
tripartite regional subdivision GO:0007351 2 0.024
microtubule based process GO:0007017 210 0.024
small molecule biosynthetic process GO:0044283 157 0.024
cell cell junction organization GO:0045216 69 0.024
positive regulation of cell death GO:0010942 263 0.024
muscle contraction GO:0006936 73 0.024
cell morphogenesis GO:0000902 296 0.024
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.024
Fly
response to abiotic stimulus GO:0009628 336 0.023
regulation of cell cycle process GO:0010564 266 0.023
negative regulation of cellular amine metabolic process GO:0033239 3 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
cell junction organization GO:0034330 79 0.023
regulation of cell cycle GO:0051726 393 0.023
mapk cascade GO:0000165 288 0.023
Human
transmembrane transport GO:0055085 399 0.023
regulation of transferase activity GO:0051338 355 0.023
Human
regulation of cellular response to stress GO:0080135 244 0.023
Human
actin filament based movement GO:0030048 17 0.022
regulation of protein kinase activity GO:0045859 289 0.022
Human
positive regulation of kinase activity GO:0033674 204 0.022
Human
positive regulation of hydrolase activity GO:0051345 331 0.022
luteinizing hormone secretion GO:0032275 1 0.022
positive regulation of hormone biosynthetic process GO:0046886 4 0.022
neuromuscular junction development GO:0007528 3 0.022
regulation of kinase activity GO:0043549 314 0.022
Human
positive regulation of cell proliferation GO:0008284 301 0.021
Human
muscle system process GO:0003012 81 0.021
cell cell signaling GO:0007267 155 0.021
regulation of actin cytoskeleton organization GO:0032956 116 0.021
Human
av node cell to bundle of his cell communication GO:0086067 4 0.021
positive regulation of mapk cascade GO:0043410 190 0.021
Human
glycerolipid metabolic process GO:0046486 107 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
Mouse
morphogenesis of a polarized epithelium GO:0001738 3 0.020
positive regulation of glucocorticoid metabolic process GO:0031945 1 0.020
cardiac muscle contraction GO:0060048 34 0.020
cellular amine metabolic process GO:0044106 41 0.020
amine metabolic process GO:0009308 44 0.020
cartilage condensation GO:0001502 1 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
Human
regulation of cell motility GO:2000145 299 0.019
Human
striated muscle contraction GO:0006941 52 0.019
positive regulation of glucocorticoid biosynthetic process GO:0031948 1 0.019
female gamete generation GO:0007292 2 0.019
plasma membrane organization GO:0007009 115 0.019
single organismal cell cell adhesion GO:0016337 148 0.019
Human
regulation of actin filament based process GO:0032970 141 0.019
Human
regulation of cellular component movement GO:0051270 334 0.018
Human
metal ion transport GO:0030001 272 0.018
Human
cellular amino acid metabolic process GO:0006520 116 0.018
oogenesis GO:0048477 2 0.018
secretion GO:0046903 254 0.018
oocyte differentiation GO:0009994 2 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
Human
negative regulation of apoptotic process GO:0043066 316 0.018
Human Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
Human
regulation of protein localization GO:0032880 296 0.018
cation transmembrane transport GO:0098655 238 0.018
embryonic forelimb morphogenesis GO:0035115 4 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.017
cardiovascular system development GO:0072358 262 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017
testosterone biosynthetic process GO:0061370 2 0.017
negative regulation of androgen biosynthetic process GO:2000180 1 0.017
nephric duct development GO:0072176 4 0.017
regulation of hormone levels GO:0010817 125 0.017
regulation of testosterone biosynthetic process GO:2000224 2 0.017
memory GO:0007613 3 0.017
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.017
positive regulation of cell motility GO:2000147 177 0.017
Human
cell adhesion GO:0007155 325 0.017
Human
actin cytoskeleton organization GO:0030036 207 0.017
Human
actin mediated cell contraction GO:0070252 12 0.017
dephosphorylation GO:0016311 209 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
epithelial cell development GO:0002064 34 0.016
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.016
secretion by cell GO:0032940 226 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
regulation of cytokine production GO:0001817 232 0.016
vasculature development GO:0001944 181 0.016
organ morphogenesis GO:0009887 147 0.016
biological adhesion GO:0022610 331 0.016
Human
axis elongation GO:0003401 4 0.016
protein localization to organelle GO:0033365 280 0.016
cellular response to oxygen containing compound GO:1901701 276 0.015
Human
paramesonephric duct development GO:0061205 2 0.015
response to transforming growth factor beta GO:0071559 94 0.015
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.015
organelle assembly GO:0070925 176 0.015
ion homeostasis GO:0050801 230 0.015
protein catabolic process GO:0030163 325 0.015
Human
modification dependent protein catabolic process GO:0019941 209 0.015
Human
angiotensin activated signaling pathway GO:0038166 4 0.015
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.015
regulation of transmembrane transport GO:0034762 139 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
action potential GO:0001508 34 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
Mouse
glycerophospholipid metabolic process GO:0006650 84 0.015
response to decreased oxygen levels GO:0036293 96 0.015
regulation of intracellular transport GO:0032386 195 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
Human Fly
positive regulation of protein phosphorylation GO:0001934 313 0.014
Human
regulation of epithelial cell differentiation GO:0030856 24 0.014
cytoplasmic transport GO:0016482 379 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
oocyte development GO:0048599 1 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
regulation of protein catabolic process GO:0042176 155 0.014
Human
cellular macromolecule catabolic process GO:0044265 380 0.014
Human
positive regulation of locomotion GO:0040017 186 0.014
Human
vesicle mediated transport GO:0016192 371 0.014
Human
rab protein signal transduction GO:0032482 4 0.014
regulation of rho gtpase activity GO:0032319 66 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
glycoprotein biosynthetic process GO:0009101 91 0.014
mitotic cell cycle process GO:1903047 286 0.014
hair follicle morphogenesis GO:0031069 2 0.014
cell aggregation GO:0098743 1 0.014
heart contraction GO:0060047 62 0.014
cilium morphogenesis GO:0060271 75 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
negative regulation of cell death GO:0060548 345 0.013
Human Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
response to growth factor GO:0070848 205 0.013
Human
regulation of proteolysis GO:0030162 293 0.013
Human
positive regulation of cellular component organization GO:0051130 376 0.013
Human
circulatory system development GO:0072359 262 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
Human
organ formation GO:0048645 3 0.013
angiogenesis GO:0001525 147 0.013
dermatome development GO:0061054 3 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
Human
carbohydrate metabolic process GO:0005975 207 0.013
lipid modification GO:0030258 84 0.013
cell division GO:0051301 168 0.013
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.013
somatic stem cell division GO:0048103 1 0.013
mitochondrion organization GO:0007005 156 0.013
regulation of vasculature development GO:1901342 97 0.013
growth GO:0040007 202 0.013
Mouse
ion transmembrane transport GO:0034220 338 0.013
maintenance of location GO:0051235 112 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
regulation of membrane potential GO:0042391 95 0.012
intracellular protein transport GO:0006886 270 0.012
establishment of protein localization to plasma membrane GO:0090002 68 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
regulation of cardiac muscle tissue growth GO:0055021 4 0.012
negative regulation of wnt signaling pathway GO:0030178 69 0.012
pattern specification process GO:0007389 43 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
protein autophosphorylation GO:0046777 123 0.012
cellular homeostasis GO:0019725 196 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
oxidation reduction process GO:0055114 396 0.012
cell cycle phase transition GO:0044770 173 0.012
neurogenesis GO:0022008 169 0.012
Human
protein targeting GO:0006605 187 0.012
cation transport GO:0006812 331 0.012
Human
developmental programmed cell death GO:0010623 3 0.012
epidermal cell differentiation GO:0009913 45 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
lung alveolus development GO:0048286 4 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
Human
cytokine production GO:0001816 247 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
cell growth GO:0016049 160 0.012
Mouse
adult locomotory behavior GO:0008344 1 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
Human
proteasomal protein catabolic process GO:0010498 176 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
Human
cell projection organization GO:0030030 252 0.012
Human
mitotic cell cycle GO:0000278 326 0.012
kidney development GO:0001822 53 0.012
neurotransmitter secretion GO:0007269 4 0.012
sodium ion transport GO:0006814 61 0.012
response to oxygen containing compound GO:1901700 369 0.011
Human
cytokinesis GO:0000910 96 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
Human
t cell differentiation in thymus GO:0033077 4 0.011
blood vessel development GO:0001568 172 0.011
endocytosis GO:0006897 159 0.011
Human
rna processing GO:0006396 255 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
wound healing GO:0042060 115 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
cloaca development GO:0035844 1 0.011
regulation of rho protein signal transduction GO:0035023 79 0.011
primary neural tube formation GO:0014020 3 0.011
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
endosomal transport GO:0016197 129 0.011
small molecule catabolic process GO:0044282 92 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
hindbrain development GO:0030902 3 0.011
cell projection assembly GO:0030031 126 0.011
steroid metabolic process GO:0008202 94 0.011
organic hydroxy compound biosynthetic process GO:1901617 71 0.011
hormone metabolic process GO:0042445 61 0.011
regulation of ion transmembrane transport GO:0034765 132 0.011
non canonical wnt signaling pathway GO:0035567 14 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
Human
tube closure GO:0060606 3 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
negative regulation of blood vessel morphogenesis GO:2000181 41 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.011
Human
neuroblast proliferation GO:0007405 4 0.011
actin filament bundle assembly GO:0051017 54 0.011
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.011
regulation of mitotic cell cycle GO:0007346 189 0.010
meiosis i GO:0007127 4 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
blastocyst development GO:0001824 3 0.010
sex determination GO:0007530 3 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010
spermatid differentiation GO:0048515 4 0.010
Fly
regulation of transporter activity GO:0032409 82 0.010
stress activated mapk cascade GO:0051403 93 0.010
Human
dna repair GO:0006281 198 0.010
cell part morphogenesis GO:0032990 137 0.010
inner ear morphogenesis GO:0042472 4 0.010
spermatid development GO:0007286 4 0.010
Fly
nitrogen compound transport GO:0071705 191 0.010
covalent chromatin modification GO:0016569 254 0.010
anion transport GO:0006820 161 0.010
cellular protein catabolic process GO:0044257 261 0.010
Human
cellular hormone metabolic process GO:0034754 41 0.010
nuclear transport GO:0051169 179 0.010
establishment of tissue polarity GO:0007164 3 0.010
stem cell division GO:0017145 2 0.010
sensory perception of taste GO:0050909 36 0.010
metal ion homeostasis GO:0055065 169 0.010

TNK1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.021
nervous system disease DOID:863 431 0.021
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
retinal disease DOID:5679 118 0.018
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
organ system cancer DOID:0050686 164 0.013
retinal degeneration DOID:8466 89 0.012
central nervous system disease DOID:331 186 0.010
neurodegenerative disease DOID:1289 102 0.010