|
|
regulation of sterol transport
|
GO:0032371 |
21 |
0.995
|
Human |
|
|
vitamin d metabolic process
|
GO:0042359 |
10 |
0.988
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.975
|
Mouse Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.968
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.964
|
Mouse Fly |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.961
|
Mouse Fly |
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.961
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.952
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.949
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.947
|
Mouse Fly |
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.938
|
Fly |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.936
|
|
|
|
negative regulation of calcidiol 1 monooxygenase activity
|
GO:0010956 |
3 |
0.926
|
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
9 |
0.924
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.917
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.898
|
Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.895
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.887
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.882
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.877
|
|
|
|
positive regulation of hyaluronan biosynthetic process
|
GO:1900127 |
3 |
0.874
|
|
|
|
positive regulation of mirna metabolic process
|
GO:2000630 |
4 |
0.872
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.851
|
Mouse |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.844
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.839
|
Fly |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.835
|
Mouse |
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
8 |
0.832
|
|
|
|
positive regulation of cholesterol efflux
|
GO:0010875 |
8 |
0.818
|
Human |
|
|
vitamin metabolic process
|
GO:0006766 |
26 |
0.813
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
1 |
0.813
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.812
|
Mouse |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.804
|
Fly |
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.802
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
247 |
0.801
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.798
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.798
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.795
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.784
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.783
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.780
|
Fly |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.778
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.777
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
27 |
0.771
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.767
|
Fly |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.755
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.745
|
Fly |
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
1 |
0.734
|
Fly |
|
|
organic acid transport
|
GO:0015849 |
65 |
0.726
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.721
|
Fly |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.718
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.695
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.689
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.689
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.687
|
|
|
|
antifungal humoral response
|
GO:0019732 |
2 |
0.680
|
Fly |
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.670
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
11 |
0.666
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.657
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.657
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.645
|
Fly |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.641
|
Fly |
|
|
negative regulation of interleukin 8 biosynthetic process
|
GO:0045415 |
3 |
0.636
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.624
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.621
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.615
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.614
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.613
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.606
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.599
|
|
|
|
regulation of interleukin 12 biosynthetic process
|
GO:0045075 |
1 |
0.599
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.583
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
8 |
0.579
|
Mouse |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.566
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.562
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.562
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.561
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.553
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.550
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.549
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
27 |
0.547
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.540
|
|
|
|
regulation of hyaluronan biosynthetic process
|
GO:1900125 |
6 |
0.537
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.529
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.528
|
Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.526
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.523
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.523
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.509
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.507
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.506
|
|
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
20 |
0.498
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.495
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.488
|
|
|
|
vitamin d biosynthetic process
|
GO:0042368 |
9 |
0.475
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.462
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.457
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.455
|
Mouse |
|
|
organic anion transport
|
GO:0015711 |
103 |
0.448
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.442
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.433
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.432
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.432
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.429
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.428
|
Fly |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.427
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.426
|
Fly |
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.425
|
Fly |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.425
|
Fly |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.425
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
11 |
0.422
|
Fly |
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.422
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.421
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.418
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.416
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.415
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.414
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.408
|
|
|
|
regulation of monooxygenase activity
|
GO:0032768 |
22 |
0.408
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.398
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.392
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.392
|
Fly |
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.389
|
|
|
|
negative regulation of lipid storage
|
GO:0010888 |
11 |
0.388
|
Human |
|
|
regulation of lipid transport
|
GO:0032368 |
44 |
0.383
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.382
|
|
|
|
negative regulation of vitamin metabolic process
|
GO:0046137 |
6 |
0.381
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.374
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.373
|
Human |
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.373
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.368
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.354
|
Fly |
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.354
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.350
|
Human |
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.348
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.344
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.342
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.341
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.332
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.326
|
Mouse |
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.322
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.316
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.315
|
|
|
|
hyaluronan metabolic process
|
GO:0030212 |
15 |
0.312
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.312
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.308
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.304
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
39 |
0.295
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.293
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.291
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.288
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.284
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
21 |
0.284
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.281
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.280
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
4 |
0.279
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.279
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.278
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.275
|
|
|
|
regulation of interleukin 8 biosynthetic process
|
GO:0045414 |
11 |
0.272
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.271
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.270
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.270
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.269
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
35 |
0.263
|
|
|
|
translation
|
GO:0006412 |
132 |
0.259
|
|
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
21 |
0.254
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.254
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.252
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.250
|
Human |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.247
|
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
6 |
0.243
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.243
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.240
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.238
|
Mouse |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.238
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.235
|
Mouse |
|
|
aminoglycan biosynthetic process
|
GO:0006023 |
29 |
0.235
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.234
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.231
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.230
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.229
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.228
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
7 |
0.227
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.226
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.225
|
Fly |
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.224
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.223
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.219
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.215
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.215
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.209
|
Human |
|
|
cellular response to nicotine
|
GO:0071316 |
4 |
0.208
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.208
|
Human |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.208
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.208
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.206
|
Mouse Fly |
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.206
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.206
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.206
|
Fly |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.204
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.203
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.203
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.201
|
|
|
|
negative regulation of steroid metabolic process
|
GO:0045939 |
15 |
0.199
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.199
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.199
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.199
|
Mouse Fly |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.198
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.196
|
|
|
|
response to uv b
|
GO:0010224 |
10 |
0.196
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.195
|
|
|
|
acute phase response
|
GO:0006953 |
5 |
0.193
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.191
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.190
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.188
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.186
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.180
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.176
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.174
|
|
|
|
negative regulation of vitamin d biosynthetic process
|
GO:0010957 |
5 |
0.173
|
|
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.173
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.172
|
Human |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.170
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.170
|
Mouse |
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.170
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.169
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.166
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.166
|
|
|
|
regulation of lipid storage
|
GO:0010883 |
21 |
0.165
|
Human |
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.165
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.164
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.163
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.163
|
Mouse |
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.159
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.157
|
|
|
|
cytoplasmic sequestering of nf kappab
|
GO:0007253 |
7 |
0.155
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.155
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.154
|
Mouse |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.148
|
|
|
|
regulation of mirna metabolic process
|
GO:2000628 |
5 |
0.148
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.147
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.147
|
|
|
|
response to interleukin 6
|
GO:0070741 |
15 |
0.147
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.147
|
Fly |
|
|
rhythmic process
|
GO:0048511 |
31 |
0.146
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.145
|
Fly |
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.144
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.143
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.141
|
Fly |
|
|
positive regulation of translation
|
GO:0045727 |
35 |
0.140
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.138
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.136
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.134
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.134
|
|
|
|
positive regulation of interleukin 4 production
|
GO:0032753 |
3 |
0.133
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.129
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.128
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.125
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.124
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.123
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.123
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.118
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.117
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.117
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.115
|
|
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.115
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.114
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.113
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.113
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.113
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.112
|
|
|
|
protein import into nucleus translocation
|
GO:0000060 |
22 |
0.112
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.111
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.111
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.110
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.110
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.109
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.108
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.107
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
27 |
0.107
|
|
|
|
macrophage activation involved in immune response
|
GO:0002281 |
1 |
0.106
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.104
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.104
|
|
|
|
regulation of calcidiol 1 monooxygenase activity
|
GO:0060558 |
6 |
0.103
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.103
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.103
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.102
|
Human |
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.102
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.102
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.101
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
10 |
0.100
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.099
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.099
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.098
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.098
|
Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.096
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.096
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.096
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.095
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.095
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.094
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.093
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.093
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.092
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.092
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.089
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.089
|
|
|
|
glycosaminoglycan biosynthetic process
|
GO:0006024 |
27 |
0.088
|
|
|
|
hyaluronan biosynthetic process
|
GO:0030213 |
10 |
0.088
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.086
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.086
|
|
|
|
negative regulation of oxidoreductase activity
|
GO:0051354 |
17 |
0.085
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.085
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.084
|
|
|
|
negative regulation of macrophage derived foam cell differentiation
|
GO:0010745 |
7 |
0.082
|
Human |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.082
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.082
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.081
|
|
|
|
negative regulation of alcohol biosynthetic process
|
GO:1902931 |
13 |
0.080
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.080
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.080
|
Mouse |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.079
|
Human |
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
5 |
0.074
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.073
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.073
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.073
|
Fly |
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.073
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.072
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.071
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.071
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.071
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.070
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.069
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.069
|
Fly |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.067
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.066
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.066
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
10 |
0.066
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.065
|
|
|
|
regulation of cholesterol efflux
|
GO:0010874 |
11 |
0.065
|
Human |
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.065
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.065
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.063
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.063
|
Human |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.063
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.062
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.061
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.060
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.059
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.059
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.059
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.058
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.058
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.058
|
|
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
9 |
0.057
|
Fly |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.057
|
|
|
|
response to exogenous dsrna
|
GO:0043330 |
10 |
0.056
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
1 |
0.056
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.056
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.055
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.055
|
Fly |
|
|
neutral amino acid transport
|
GO:0015804 |
9 |
0.055
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.055
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.054
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.054
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.053
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.053
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.053
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.053
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.053
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.052
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.052
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.052
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
8 |
0.051
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.051
|
Fly |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.051
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.050
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.050
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.050
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.050
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.050
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.049
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.049
|
Mouse |
|
|
response to ketone
|
GO:1901654 |
19 |
0.049
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.049
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.049
|
Human |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.049
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
25 |
0.049
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.048
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.048
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.048
|
Human |
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.048
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.047
|
|
|
|
d amino acid transport
|
GO:0042940 |
3 |
0.046
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.046
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.046
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.046
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.045
|
|
|
|
angiogenesis involved in wound healing
|
GO:0060055 |
4 |
0.045
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.044
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.043
|
|
|
|
bone trabecula morphogenesis
|
GO:0061430 |
1 |
0.043
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.043
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.043
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.043
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.043
|
Human |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.043
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.043
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.043
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.042
|
Mouse |
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.042
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.042
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.041
|
|
|
|
vitamin biosynthetic process
|
GO:0009110 |
11 |
0.041
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.041
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.040
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.040
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
17 |
0.040
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.040
|
|
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.039
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.039
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.039
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.039
|
|
|
|
positive regulation of interleukin 13 production
|
GO:0032736 |
4 |
0.039
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.039
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.039
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.038
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.038
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
13 |
0.038
|
Mouse |
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.038
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.038
|
Fly |
|
|
response to hexose
|
GO:0009746 |
20 |
0.038
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.038
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.037
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.037
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.037
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.037
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
10 |
0.037
|
Mouse |
|
|
response to nicotine
|
GO:0035094 |
12 |
0.037
|
|
|
|
phospholipid catabolic process
|
GO:0009395 |
12 |
0.037
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
8 |
0.036
|
Fly |
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.036
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.036
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.036
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.036
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.036
|
Mouse |
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.036
|
|
|
|
positive regulation of lipid storage
|
GO:0010884 |
10 |
0.035
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.035
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.035
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.035
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.034
|
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.034
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.034
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.034
|
Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.034
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.034
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.033
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.033
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.033
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.033
|
|
|
|
regulation of macrophage derived foam cell differentiation
|
GO:0010743 |
14 |
0.033
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.033
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.033
|
Mouse |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.032
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.032
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.032
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.031
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.031
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.031
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.031
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.031
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.031
|
Human |
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
27 |
0.031
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.031
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.031
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.030
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.030
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.030
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.030
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.029
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.029
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.029
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.029
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
20 |
0.029
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.029
|
Human |
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.029
|
Fly |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
5 |
0.029
|
Mouse |
