Homo sapiens

49 known processes

NKX2-8

NK2 homeobox 8

(Aliases: NKX2.8,NKX2H,Nkx2-9)

NKX2-8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
menstrual cycle phase GO:0022601 2 0.289
regulation of cell differentiation GO:0045595 393 0.257
Human
cardiac cell fate determination GO:0060913 3 0.256
cardiac right ventricle morphogenesis GO:0003215 3 0.234
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.207
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.202
Human
neuron fate commitment GO:0048663 2 0.192
negative regulation of apoptotic process GO:0043066 316 0.191
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.181
Human
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.177
organ formation GO:0048645 3 0.176
cell development GO:0048468 328 0.173
Human Mouse
regulation of locomotion GO:0040012 329 0.172
Human
positive regulation of developmental process GO:0051094 314 0.171
Human
negative regulation of cell death GO:0060548 345 0.170
Human
forebrain regionalization GO:0021871 3 0.168
cardiovascular system development GO:0072358 262 0.165
Human
cellular ketone metabolic process GO:0042180 80 0.134
epithelium development GO:0060429 227 0.132
Human
cation transmembrane transport GO:0098655 238 0.131
positive regulation of cell differentiation GO:0045597 211 0.125
Human
negative regulation of cell differentiation GO:0045596 171 0.120
Human
cellular response to endogenous stimulus GO:0071495 336 0.119
Human
regulation of cellular amine metabolic process GO:0033238 11 0.118
response to lipid GO:0033993 206 0.118
regulation of cell development GO:0060284 161 0.116
Human
negative regulation of programmed cell death GO:0043069 321 0.114
Human
nervous system development GO:0007399 293 0.111
Human Zebrafish Mouse
cell cell signaling GO:0007267 155 0.109
forebrain dorsal ventral pattern formation GO:0021798 1 0.107
negative regulation of developmental process GO:0051093 247 0.104
Human
segmentation GO:0035282 4 0.102
amine metabolic process GO:0009308 44 0.101
regulation of cellular ketone metabolic process GO:0010565 50 0.100
negative regulation of multicellular organismal process GO:0051241 317 0.097
Human
muscle structure development GO:0061061 98 0.093
Human Worm
cellular component morphogenesis GO:0032989 314 0.090
Human Mouse
cellular amino acid metabolic process GO:0006520 116 0.086
stem cell differentiation GO:0048863 93 0.086
Human
system process GO:0003008 349 0.082
response to hormone GO:0009725 175 0.082
Human
regulation of cellular component movement GO:0051270 334 0.081
Human
response to oxygen containing compound GO:1901700 369 0.081
cellular amine metabolic process GO:0044106 41 0.080
post embryonic development GO:0009791 2 0.080
specification of organ identity GO:0010092 3 0.080
response to organic cyclic compound GO:0014070 204 0.078
regulation of anatomical structure morphogenesis GO:0022603 286 0.076
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.075
head development GO:0060322 108 0.075
Human
cell fate determination GO:0001709 3 0.074
locomotory behavior GO:0007626 1 0.074
cell morphogenesis GO:0000902 296 0.072
Human Mouse
globus pallidus development GO:0021759 1 0.072
Human
lipid metabolic process GO:0006629 381 0.072
forebrain generation of neurons GO:0021872 3 0.071
regulation of cellular amino acid metabolic process GO:0006521 6 0.071
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.070
positive regulation of phosphorylation GO:0042327 394 0.069
response to abiotic stimulus GO:0009628 336 0.066
positive regulation of cell proliferation GO:0008284 301 0.066
peripheral nervous system development GO:0007422 2 0.065
stem cell development GO:0048864 69 0.065
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.064
enzyme linked receptor protein signaling pathway GO:0007167 303 0.064
Human
regulation of cell morphogenesis GO:0022604 153 0.062
Human
cranial nerve development GO:0021545 4 0.061
behavior GO:0007610 112 0.061
circulatory system development GO:0072359 262 0.061
Human
bmp signaling pathway involved in heart development GO:0061312 3 0.061
positive regulation of apoptotic process GO:0043065 246 0.059
regulation of neuron differentiation GO:0045664 70 0.059
Human
organ morphogenesis GO:0009887 147 0.059
Human
cytoplasmic transport GO:0016482 379 0.058
central nervous system development GO:0007417 123 0.056
Human Zebrafish
regulation of cell motility GO:2000145 299 0.056
Human
outflow tract septum morphogenesis GO:0003148 4 0.056
Human
cation transport GO:0006812 331 0.056
epithelial cell differentiation GO:0030855 141 0.055
positive regulation of transport GO:0051050 336 0.053
regulation of cell migration GO:0030334 289 0.052
Human
mapk cascade GO:0000165 288 0.052
regulation of cell cycle GO:0051726 393 0.051
cell morphogenesis involved in differentiation GO:0000904 144 0.051
Human Mouse
hindbrain development GO:0030902 3 0.051
transmembrane transport GO:0055085 399 0.050
positive regulation of programmed cell death GO:0043068 249 0.049
secretion GO:0046903 254 0.049
neuron differentiation GO:0030182 138 0.049
Human Zebrafish Mouse
motor neuron axon guidance GO:0008045 2 0.049
micturition GO:0060073 3 0.048
extraocular skeletal muscle development GO:0002074 1 0.047
positive regulation of tooth mineralization GO:0070172 2 0.046
cellular response to oxygen containing compound GO:1901701 276 0.045
regulation of neurogenesis GO:0050767 82 0.045
Human
positive regulation of cell death GO:0010942 263 0.045
neurogenesis GO:0022008 169 0.045
Human Zebrafish Mouse
vasculature development GO:0001944 181 0.045
tube development GO:0035295 125 0.045
Human Mouse Worm
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.044
organic hydroxy compound metabolic process GO:1901615 147 0.044
response to organonitrogen compound GO:0010243 156 0.043
neuron projection development GO:0031175 106 0.043
Mouse
vesicle mediated transport GO:0016192 371 0.043
Worm
forebrain neuron differentiation GO:0021879 3 0.043
epidermis morphogenesis GO:0048730 3 0.043
positive regulation of mapk cascade GO:0043410 190 0.043
morphogenesis of embryonic epithelium GO:0016331 4 0.043
paramesonephric duct development GO:0061205 2 0.043
signal transduction by phosphorylation GO:0023014 297 0.042
skeletal system development GO:0001501 79 0.042
secretion by cell GO:0032940 226 0.042
nerve development GO:0021675 4 0.042
multicellular organismal aging GO:0010259 3 0.041
cellular response to dna damage stimulus GO:0006974 379 0.041
ion transmembrane transport GO:0034220 338 0.041
cell projection organization GO:0030030 252 0.041
Mouse
embryonic forelimb morphogenesis GO:0035115 4 0.041
regulation of nervous system development GO:0051960 88 0.040
Human
reactive oxygen species metabolic process GO:0072593 75 0.040
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.040
Human
somatic stem cell maintenance GO:0035019 4 0.040
heart formation GO:0060914 2 0.040
positive regulation of cellular component organization GO:0051130 376 0.040
negative regulation of cell motility GO:2000146 104 0.039
Human
generation of neurons GO:0048699 152 0.039
Human Zebrafish Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.039
organonitrogen compound biosynthetic process GO:1901566 200 0.039
response to biotic stimulus GO:0009607 276 0.038
regulation of thyroid hormone generation GO:2000609 2 0.038
determination of adult lifespan GO:0008340 2 0.038
mating GO:0007618 1 0.038
gland development GO:0048732 48 0.037
Human
regulation of ion transport GO:0043269 189 0.037
blastoderm segmentation GO:0007350 2 0.037
positive regulation of protein phosphorylation GO:0001934 313 0.037
somatostatin signaling pathway GO:0038170 1 0.036
apoptotic signaling pathway GO:0097190 268 0.036
regulation of proteolysis GO:0030162 293 0.036
negative regulation of catalytic activity GO:0043086 335 0.036
positive regulation of cell development GO:0010720 92 0.036
Human
regulation of methylation dependent chromatin silencing GO:0090308 3 0.036
response to other organism GO:0051707 261 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
regulation of secretion GO:0051046 194 0.035
response to decreased oxygen levels GO:0036293 96 0.035
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.035
growth GO:0040007 202 0.035
single organism cellular localization GO:1902580 332 0.034
negative regulation of protein metabolic process GO:0051248 391 0.034
embryonic epithelial tube formation GO:0001838 4 0.034
calcium ion transport GO:0006816 147 0.034
thymus development GO:0048538 3 0.034
response to alcohol GO:0097305 64 0.034
response to external biotic stimulus GO:0043207 261 0.034
immune response GO:0006955 307 0.034
soft palate development GO:0060023 3 0.034
regulation of response to external stimulus GO:0032101 222 0.033
protein maturation GO:0051604 233 0.033
ion homeostasis GO:0050801 230 0.033
hair follicle morphogenesis GO:0031069 2 0.033
brain development GO:0007420 97 0.033
Human
chromatin organization GO:0006325 351 0.033
cation homeostasis GO:0055080 189 0.032
cell differentiation in spinal cord GO:0021515 1 0.032
Zebrafish
regulation of transferase activity GO:0051338 355 0.032
regulation of mapk cascade GO:0043408 262 0.032
cytokine production GO:0001816 247 0.032
cellular response to hormone stimulus GO:0032870 125 0.032
forelimb morphogenesis GO:0035136 4 0.032
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.032
forebrain development GO:0030900 26 0.031
Human
regulation of metanephros size GO:0035566 1 0.031
chemical homeostasis GO:0048878 306 0.031
negative regulation of cell migration GO:0030336 102 0.031
Human
inorganic cation transmembrane transport GO:0098662 194 0.031
regulation of reactive oxygen species metabolic process GO:2000377 41 0.031
pattern specification process GO:0007389 43 0.031
mitotic cell cycle GO:0000278 326 0.031
digestive system development GO:0055123 75 0.031
Worm
positive regulation of cell cycle GO:0045787 140 0.030
opioid receptor signaling pathway GO:0038003 4 0.030
embryonic morphogenesis GO:0048598 85 0.030
pituitary gland development GO:0021983 2 0.030
immune system development GO:0002520 195 0.030
Human
protein localization to organelle GO:0033365 280 0.030
actin filament based process GO:0030029 224 0.030
regulation of cell cycle process GO:0010564 266 0.030
defense response GO:0006952 315 0.030
protein catabolic process GO:0030163 325 0.030
regulation of epithelial to mesenchymal transition GO:0010717 37 0.029
Human
negative regulation of cellular component organization GO:0051129 235 0.029
Human
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 1 0.029
cell adhesion GO:0007155 325 0.029
female gamete generation GO:0007292 2 0.029
regulation of cytokine production GO:0001817 232 0.029
response to wounding GO:0009611 168 0.029
muscle system process GO:0003012 81 0.029
cellular response to cytokine stimulus GO:0071345 181 0.029
regulation of protein localization GO:0032880 296 0.029
regulation of apoptotic signaling pathway GO:2001233 175 0.029
cellular macromolecule catabolic process GO:0044265 380 0.029
tube morphogenesis GO:0035239 95 0.029
Human
regeneration GO:0031099 4 0.028
morphogenesis of an epithelium GO:0002009 60 0.028
Human
regulation of hormone levels GO:0010817 125 0.028
inner ear morphogenesis GO:0042472 4 0.028
regulation of cysteine type endopeptidase activity GO:2000116 127 0.028
regulation of male gonad development GO:2000018 4 0.028
metencephalon development GO:0022037 2 0.028
wnt signaling pathway GO:0016055 156 0.027
muscle contraction GO:0006936 73 0.027
cell part morphogenesis GO:0032990 137 0.027
Mouse
protein processing GO:0016485 226 0.027
endocrine system development GO:0035270 26 0.027
Human
somatostatin receptor signaling pathway GO:0038169 1 0.027
mesenchymal cell differentiation GO:0048762 52 0.027
Human
mesenchymal cell development GO:0014031 50 0.027
Human
hormone secretion GO:0046879 65 0.027
regulation of peptidase activity GO:0052547 180 0.027
regulation of epithelial cell proliferation GO:0050678 113 0.027
Mouse
regulation of protein transport GO:0051223 213 0.027
cerebellum development GO:0021549 2 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
regulation of stem cell differentiation GO:2000736 56 0.026
Human
response to steroid hormone GO:0048545 80 0.026
response to nitrogen compound GO:1901698 184 0.026
response to oxygen levels GO:0070482 100 0.026
tissue morphogenesis GO:0048729 96 0.026
Human
positive regulation of immune system process GO:0002684 283 0.026
hemopoiesis GO:0030097 180 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.026
Human
positive regulation of hydrolase activity GO:0051345 331 0.025
neuron development GO:0048666 113 0.025
Mouse
luteinizing hormone secretion GO:0032275 1 0.025
monovalent inorganic cation transport GO:0015672 128 0.025
leukocyte migration GO:0050900 107 0.025
posttranscriptional regulation of gene expression GO:0010608 213 0.025
positive regulation of catabolic process GO:0009896 310 0.025
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
positive regulation of cytokine production GO:0001819 167 0.025
rhythmic behavior GO:0007622 2 0.025
membrane organization GO:0061024 292 0.025
hard palate development GO:0060022 1 0.025
response to transforming growth factor beta GO:0071559 94 0.025
Human
positive regulation of cardioblast differentiation GO:0051891 2 0.025
single organism membrane organization GO:0044802 268 0.025
biological adhesion GO:0022610 331 0.025
mesenchyme development GO:0060485 59 0.025
Human
cellular calcium ion homeostasis GO:0006874 117 0.025
oogenesis GO:0048477 2 0.025
memory GO:0007613 3 0.025
neuromuscular junction development GO:0007528 3 0.025
cellular lipid metabolic process GO:0044255 303 0.025
adult locomotory behavior GO:0008344 1 0.025
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.025
regulation of canonical wnt signaling pathway GO:0060828 88 0.025
cellular protein catabolic process GO:0044257 261 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
regulation of mitotic cell cycle GO:0007346 189 0.024
regulation of kinase activity GO:0043549 314 0.024
embryonic camera type eye development GO:0031076 2 0.024
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.024
pulmonary vein morphogenesis GO:0060577 1 0.024
reproductive process GO:0022414 106 0.024
reactive oxygen species biosynthetic process GO:1903409 4 0.024
negative regulation of transport GO:0051051 176 0.024
regulation of endopeptidase activity GO:0052548 170 0.024
sensory perception of pain GO:0019233 4 0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.024
protein localization to nucleus GO:0034504 136 0.024
angiogenesis GO:0001525 147 0.024
copulation GO:0007620 1 0.024
male genitalia development GO:0030539 1 0.024
response to growth factor GO:0070848 205 0.024
Human
anterior posterior axis specification GO:0009948 2 0.023
regulation of cardioblast differentiation GO:0051890 4 0.023
circadian behavior GO:0048512 2 0.023
negative regulation of locomotion GO:0040013 118 0.023
Human
negative regulation of wnt protein secretion GO:0061358 1 0.023
positive regulation of glucocorticoid secretion GO:2000851 4 0.023
intracellular protein transport GO:0006886 270 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
regulation of multi organism process GO:0043900 157 0.023
canonical wnt signaling pathway GO:0060070 116 0.023
cardiac muscle cell contraction GO:0086003 4 0.023
monocarboxylic acid metabolic process GO:0032787 185 0.023
regulation of cell projection organization GO:0031344 107 0.023
spinal cord development GO:0021510 4 0.023
Zebrafish
regulation of protein maturation GO:1903317 150 0.023
circulatory system process GO:0003013 113 0.023
negative regulation of protein modification process GO:0031400 200 0.023
divalent inorganic cation transport GO:0072511 158 0.023
regulation of establishment of protein localization GO:0070201 242 0.023
cellular cation homeostasis GO:0030003 163 0.022
reactive nitrogen species metabolic process GO:2001057 3 0.022
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.022
endodermal mesodermal cell signaling GO:0003133 3 0.022
positive regulation of odontogenesis GO:0042482 3 0.022
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.022
Human
negative regulation of cell cycle GO:0045786 193 0.022
positive regulation of organelle organization GO:0010638 195 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
Human
negative regulation of protein processing GO:0010955 142 0.022
response to hypoxia GO:0001666 96 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.021
photoreceptor cell differentiation GO:0046530 2 0.021
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.021
embryo development GO:0009790 123 0.021
Human
regulation of growth GO:0040008 165 0.021
striated muscle cell differentiation GO:0051146 43 0.021
Human
negative regulation of cell development GO:0010721 48 0.021
Human
metal ion transport GO:0030001 272 0.021
nitrogen compound transport GO:0071705 191 0.021
cell growth GO:0016049 160 0.021
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.021
covalent chromatin modification GO:0016569 254 0.021
hormone metabolic process GO:0042445 61 0.021
heart field specification GO:0003128 2 0.021
cell projection morphogenesis GO:0048858 129 0.021
Mouse
limbic system development GO:0021761 3 0.021
cyclic nucleotide biosynthetic process GO:0009190 61 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
actin cytoskeleton organization GO:0030036 207 0.021
cellular homeostasis GO:0019725 196 0.021
cellular chemical homeostasis GO:0055082 180 0.020
negative regulation of protein maturation GO:1903318 142 0.020
regulation of cellular response to stress GO:0080135 244 0.020
regulation of immune response GO:0050776 201 0.020
response to axon injury GO:0048678 1 0.020
positive regulation of neurogenesis GO:0050769 49 0.020
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.020
Human
positive regulation of transferase activity GO:0051347 227 0.020
regulation of protein kinase activity GO:0045859 289 0.020
regulation of cell division GO:0051302 116 0.020
mitotic cell cycle process GO:1903047 286 0.020
protein ubiquitination GO:0016567 314 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
chromatin modification GO:0016568 298 0.020
positive regulation of synaptic transmission GO:0050806 4 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
cytosolic calcium ion homeostasis GO:0051480 89 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
blastocyst development GO:0001824 3 0.020
neurological system process GO:0050877 163 0.020
metal ion homeostasis GO:0055065 169 0.020
epithelial to mesenchymal transition GO:0001837 48 0.020
Human
second messenger mediated signaling GO:0019932 78 0.019
cell type specific apoptotic process GO:0097285 125 0.019
Human
positive regulation of neuron differentiation GO:0045666 40 0.019
Human
menstruation GO:0042703 1 0.019
positive regulation of proteolysis GO:0045862 142 0.019
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.019
immune effector process GO:0002252 159 0.019
heart development GO:0007507 95 0.019
Human
negative regulation of stem cell differentiation GO:2000737 22 0.019
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
regulation of system process GO:0044057 101 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
compound eye development GO:0048749 1 0.019
ras protein signal transduction GO:0007265 73 0.019
regulation of cytoplasmic transport GO:1903649 149 0.019
blood vessel development GO:0001568 172 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
cell division GO:0051301 168 0.019
muscle tissue development GO:0060537 62 0.019
Human
endodermal cell fate specification GO:0001714 4 0.019
negative regulation of cellular component movement GO:0051271 106 0.019
Human
regulation of cellular response to growth factor stimulus GO:0090287 76 0.019
Human
action potential GO:0001508 34 0.019
syncytium formation by plasma membrane fusion GO:0000768 2 0.019
behavioral response to ethanol GO:0048149 2 0.018
heart morphogenesis GO:0003007 48 0.018
Human
muscle organ development GO:0007517 56 0.018
Human Worm
regulation of cardiac muscle cell apoptotic process GO:0010665 3 0.018
Human
regulation of nucleotide biosynthetic process GO:0030808 50 0.018
intracellular receptor signaling pathway GO:0030522 104 0.018
cellular potassium ion transport GO:0071804 60 0.018
oxidation reduction process GO:0055114 396 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
histone modification GO:0016570 251 0.018
blood vessel morphogenesis GO:0048514 162 0.018
g protein coupled receptor signaling pathway GO:0007186 207 0.018
regionalization GO:0003002 29 0.018
gabaergic neuron differentiation GO:0097154 1 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
somatic muscle development GO:0007525 1 0.018
follicle stimulating hormone secretion GO:0046884 3 0.018
associative learning GO:0008306 1 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
ameboidal type cell migration GO:0001667 135 0.018
regulation of protein complex assembly GO:0043254 147 0.018
neural tube formation GO:0001841 3 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
regulation of metal ion transport GO:0010959 120 0.017
actin filament based movement GO:0030048 17 0.017
regulation of membrane potential GO:0042391 95 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
trophectodermal cell differentiation GO:0001829 3 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
cell activation GO:0001775 213 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
embryonic camera type eye formation GO:0060900 2 0.017
innate immune response GO:0045087 178 0.017
endodermal cell fate commitment GO:0001711 4 0.017
negative regulation of proteolysis GO:0045861 132 0.017
endodermal mesodermal cell signaling involved in heart induction GO:0003134 3 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
positive regulation of cell motility GO:2000147 177 0.017
neuroblast proliferation GO:0007405 4 0.017
chemotaxis GO:0006935 157 0.017
striated muscle tissue development GO:0014706 59 0.017
Human
digestive tract development GO:0048565 75 0.017
Worm
response to estrogen GO:0043627 47 0.017
regulation of organ formation GO:0003156 4 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
nucleotide biosynthetic process GO:0009165 109 0.017
negative regulation of camp mediated signaling GO:0043951 4 0.017
multicellular organismal response to stress GO:0033555 1 0.017
embryonic viscerocranium morphogenesis GO:0048703 1 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.017
regulation of anatomical structure size GO:0090066 101 0.017
single organism reproductive process GO:0044702 98 0.017
cerebral cortex cell migration GO:0021795 3 0.017
cardiac right ventricle formation GO:0003219 1 0.017
positive regulation of locomotion GO:0040017 186 0.017
organelle assembly GO:0070925 176 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
taxis GO:0042330 157 0.016
developmental programmed cell death GO:0010623 3 0.016
muscle cell differentiation GO:0042692 63 0.016
Human
regulation of heart induction GO:0090381 2 0.016
positive regulation of cell division GO:0051781 59 0.016
positive regulation of nervous system development GO:0051962 54 0.016
Human
striated muscle cell apoptotic process GO:0010658 3 0.016
Human
regulation of heart morphogenesis GO:2000826 4 0.016
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.016
organic anion transport GO:0015711 103 0.016
dna repair GO:0006281 198 0.016
regulation of protein processing GO:0070613 150 0.016
signal release GO:0023061 70 0.016
cellular ion homeostasis GO:0006873 168 0.016
tripartite regional subdivision GO:0007351 2 0.016
positive regulation of kinase activity GO:0033674 204 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
protein oligomerization GO:0051259 173 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
Mouse
response to cytokine GO:0034097 232 0.016
regulation of cell growth GO:0001558 135 0.016
viral process GO:0016032 146 0.016
regulation of intracellular transport GO:0032386 195 0.016
epithelial cell proliferation GO:0050673 128 0.016
Mouse
lymphocyte activation GO:0046649 133 0.016
artery smooth muscle contraction GO:0014824 3 0.016
blood circulation GO:0008015 113 0.016
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.016
sensory organ development GO:0007423 52 0.015
neuroendocrine cell differentiation GO:0061101 2 0.015
response to radiation GO:0009314 151 0.015
hormone transport GO:0009914 68 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
rho protein signal transduction GO:0007266 26 0.015
regulation of secretion by cell GO:1903530 177 0.015
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
regulation of heart growth GO:0060420 4 0.015
calcium ion homeostasis GO:0055074 122 0.015
myoblast fusion GO:0007520 1 0.015
single organism cell adhesion GO:0098602 179 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.015
amide transport GO:0042886 76 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
glycine import GO:0036233 1 0.015
tissue regeneration GO:0042246 3 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
establishment of protein localization to organelle GO:0072594 172 0.015

NKX2-8 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.024
nervous system disease DOID:863 431 0.024
musculoskeletal system disease DOID:17 223 0.022
disease of cellular proliferation DOID:14566 174 0.021
immune system disease DOID:2914 155 0.019
central nervous system disease DOID:331 186 0.017
cancer DOID:162 167 0.016
organ system cancer DOID:0050686 164 0.016
connective tissue disease DOID:65 109 0.015