Homo sapiens

0 known processes

KLHL23

kelch-like 23 (Drosophila)

(Aliases: MGC2610,MGC22679,FLJ41460,DITHP,FLJ37812)

KLHL23 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.062
post embryonic development GO:0009791 2 0.061
determination of adult lifespan GO:0008340 2 0.050
defense response GO:0006952 315 0.047
multicellular organismal aging GO:0010259 3 0.047
amine metabolic process GO:0009308 44 0.046
immune response GO:0006955 307 0.043
cellular ketone metabolic process GO:0042180 80 0.042
regulation of cellular ketone metabolic process GO:0010565 50 0.042
regulation of cellular amine metabolic process GO:0033238 11 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
cellular component morphogenesis GO:0032989 314 0.039
cellular amine metabolic process GO:0044106 41 0.039
epithelium development GO:0060429 227 0.039
Human
protein catabolic process GO:0030163 325 0.039
Human
negative regulation of catalytic activity GO:0043086 335 0.039
cellular macromolecule catabolic process GO:0044265 380 0.038
Human
membrane organization GO:0061024 292 0.037
Human
regeneration GO:0031099 4 0.037
transmembrane transport GO:0055085 399 0.036
cell morphogenesis GO:0000902 296 0.036
cellular protein catabolic process GO:0044257 261 0.036
Human
negative regulation of multicellular organismal process GO:0051241 317 0.036
response to abiotic stimulus GO:0009628 336 0.036
response to other organism GO:0051707 261 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.036
hemopoiesis GO:0030097 180 0.035
ras protein signal transduction GO:0007265 73 0.033
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.032
cardiovascular system development GO:0072358 262 0.032
positive regulation of cellular amine metabolic process GO:0033240 7 0.032
segmentation GO:0035282 4 0.031
small gtpase mediated signal transduction GO:0007264 78 0.031
system process GO:0003008 349 0.031
Human
hindbrain development GO:0030902 3 0.031
positive regulation of cell death GO:0010942 263 0.031
neuromuscular junction development GO:0007528 3 0.030
positive regulation of cellular component organization GO:0051130 376 0.030
nervous system development GO:0007399 293 0.029
female gamete generation GO:0007292 2 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
Human
defense response to other organism GO:0098542 129 0.028
regulation of cell cycle GO:0051726 393 0.028
Human
protein ubiquitination GO:0016567 314 0.028
Human
ribonucleoside catabolic process GO:0042454 406 0.028
rho protein signal transduction GO:0007266 26 0.028
response to external biotic stimulus GO:0043207 261 0.028
positive regulation of apoptotic process GO:0043065 246 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
cell projection organization GO:0030030 252 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
negative regulation of protein metabolic process GO:0051248 391 0.027
Human
circulatory system development GO:0072359 262 0.026
positive regulation of developmental process GO:0051094 314 0.026
vesicle mediated transport GO:0016192 371 0.026
Human
organ morphogenesis GO:0009887 147 0.026
Human
regulation of cell cycle process GO:0010564 266 0.026
Human
positive regulation of transport GO:0051050 336 0.026
cellular response to endogenous stimulus GO:0071495 336 0.026
regulation of locomotion GO:0040012 329 0.026
locomotory behavior GO:0007626 1 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
chromatin modification GO:0016568 298 0.025
regulation of transferase activity GO:0051338 355 0.025
regulation of protein kinase activity GO:0045859 289 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
secretion GO:0046903 254 0.024
positive regulation of organelle organization GO:0010638 195 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
response to biotic stimulus GO:0009607 276 0.024
cell division GO:0051301 168 0.024
Human
growth GO:0040007 202 0.024
cell development GO:0048468 328 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
oogenesis GO:0048477 2 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
biological adhesion GO:0022610 331 0.023
positive regulation of cell proliferation GO:0008284 301 0.023
tissue regeneration GO:0042246 3 0.023
chemical homeostasis GO:0048878 306 0.023
Human
metal ion transport GO:0030001 272 0.023
Human
ribonucleotide catabolic process GO:0009261 405 0.023
mitotic cell cycle GO:0000278 326 0.023
protein modification by small protein conjugation GO:0032446 342 0.022
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
immune effector process GO:0002252 159 0.022
viral process GO:0016032 146 0.022
nucleotide catabolic process GO:0009166 408 0.022
regulation of kinase activity GO:0043549 314 0.022
purine containing compound catabolic process GO:0072523 411 0.022
signal transduction by phosphorylation GO:0023014 297 0.021
regulation of cellular component movement GO:0051270 334 0.021
chromatin organization GO:0006325 351 0.021
cell activation GO:0001775 213 0.021
hematopoietic or lymphoid organ development GO:0048534 186 0.021
cytoplasmic transport GO:0016482 379 0.021
Human
endocytosis GO:0006897 159 0.021
response to oxygen containing compound GO:1901700 369 0.021
positive regulation of immune system process GO:0002684 283 0.021
regulation of establishment of protein localization GO:0070201 242 0.021
organophosphate catabolic process GO:0046434 430 0.021
regulation of cell migration GO:0030334 289 0.021
ion transmembrane transport GO:0034220 338 0.021
covalent chromatin modification GO:0016569 254 0.021
negative regulation of transport GO:0051051 176 0.020
secretion by cell GO:0032940 226 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
Human
regulation of mitotic cell cycle GO:0007346 189 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
glial cell migration GO:0008347 4 0.020
cellular response to hormone stimulus GO:0032870 125 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
protein localization to organelle GO:0033365 280 0.020
Human
negative regulation of developmental process GO:0051093 247 0.020
cellular response to glucocorticoid stimulus GO:0071385 4 0.020
cellular response to cytokine stimulus GO:0071345 181 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.020
interspecies interaction between organisms GO:0044419 156 0.019
negative regulation of cell differentiation GO:0045596 171 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
nitrogen compound transport GO:0071705 191 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
histone modification GO:0016570 251 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
response to cytokine GO:0034097 232 0.019
lipid metabolic process GO:0006629 381 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
Human
regulation of protein localization GO:0032880 296 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
response to virus GO:0009615 126 0.018
innate immune response GO:0045087 178 0.018
nucleoside catabolic process GO:0009164 408 0.018
epithelial cell differentiation GO:0030855 141 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
organonitrogen compound biosynthetic process GO:1901566 200 0.018
regulation of mapk cascade GO:0043408 262 0.018
mapk cascade GO:0000165 288 0.018
regulation of secretion GO:0051046 194 0.018
single organism membrane organization GO:0044802 268 0.018
Human
negative regulation of cell death GO:0060548 345 0.018
Human
positive regulation of catabolic process GO:0009896 310 0.018
apoptotic signaling pathway GO:0097190 268 0.018
ion homeostasis GO:0050801 230 0.018
Human
myeloid cell differentiation GO:0030099 117 0.018
protein maturation GO:0051604 233 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
generation of neurons GO:0048699 152 0.018
head development GO:0060322 108 0.018
blastoderm segmentation GO:0007350 2 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
microtubule based process GO:0007017 210 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
neurogenesis GO:0022008 169 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
peripheral nervous system development GO:0007422 2 0.017
immune system development GO:0002520 195 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
nuclear transport GO:0051169 179 0.017
regulation of protein transport GO:0051223 213 0.017
regulation of cell differentiation GO:0045595 393 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
negative regulation of protein modification process GO:0031400 200 0.017
regulation of multi organism process GO:0043900 157 0.017
multi organism cellular process GO:0044764 156 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
regulation of protein serine threonine kinase activity GO:0071900 179 0.017
protein oligomerization GO:0051259 173 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.016
mitochondrion organization GO:0007005 156 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
positive regulation of cell cycle GO:0045787 140 0.016
cell part morphogenesis GO:0032990 137 0.016
cytokine production GO:0001816 247 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
neuron differentiation GO:0030182 138 0.016
negative regulation of transferase activity GO:0051348 124 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
negative regulation of apoptotic process GO:0043066 316 0.015
Human
negative regulation of protein phosphorylation GO:0001933 140 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
regulation of cell motility GO:2000145 299 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
negative regulation of immune system process GO:0002683 136 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
cell adhesion GO:0007155 325 0.015
cell fate determination GO:0001709 3 0.015
memory GO:0007613 3 0.015
cation transport GO:0006812 331 0.015
Human
cell projection morphogenesis GO:0048858 129 0.015
regulation of gtpase activity GO:0043087 180 0.015
regulation of immune response GO:0050776 201 0.015
response to organic cyclic compound GO:0014070 204 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
viral life cycle GO:0019058 132 0.015
mitotic cell cycle process GO:1903047 286 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
Human
vasculature development GO:0001944 181 0.015
regulation of homeostatic process GO:0032844 121 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
behavior GO:0007610 112 0.014
dephosphorylation GO:0016311 209 0.014
blood vessel development GO:0001568 172 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
cation transmembrane transport GO:0098655 238 0.014
glycoprotein metabolic process GO:0009100 110 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
spermatid differentiation GO:0048515 4 0.014
regulation of cellular response to stress GO:0080135 244 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
Human
organ formation GO:0048645 3 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.014
cellular chemical homeostasis GO:0055082 180 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
regulation of proteolysis GO:0030162 293 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
brain development GO:0007420 97 0.014
maintenance of location GO:0051235 112 0.014
wnt signaling pathway GO:0016055 156 0.014
Human
cellular homeostasis GO:0019725 196 0.014
negative regulation of kinase activity GO:0033673 106 0.014
cation homeostasis GO:0055080 189 0.014
intracellular protein transport GO:0006886 270 0.014
defense response to virus GO:0051607 71 0.014
response to growth factor GO:0070848 205 0.014
metencephalon development GO:0022037 2 0.014
compound eye development GO:0048749 1 0.014
cell cycle phase transition GO:0044770 173 0.014
actin filament based process GO:0030029 224 0.014
response to radiation GO:0009314 151 0.014
regulation of secretion by cell GO:1903530 177 0.014
neuron development GO:0048666 113 0.014
gtp catabolic process GO:0006184 237 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
positive regulation of kinase activity GO:0033674 204 0.014
single organism cellular localization GO:1902580 332 0.013
Human
cerebellum development GO:0021549 2 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
positive regulation of transferase activity GO:0051347 227 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
ameboidal type cell migration GO:0001667 135 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.013
blood vessel morphogenesis GO:0048514 162 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
adult locomotory behavior GO:0008344 1 0.013
response to metal ion GO:0010038 84 0.013
midbrain development GO:0030901 45 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
single organism membrane fusion GO:0044801 37 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
neural tube formation GO:0001841 3 0.013
leukocyte activation GO:0045321 164 0.013
cellular lipid metabolic process GO:0044255 303 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
regulation of intracellular transport GO:0032386 195 0.013
oxidation reduction process GO:0055114 396 0.013
regulation of response to external stimulus GO:0032101 222 0.013
protein targeting GO:0006605 187 0.013
positive regulation of cell migration GO:0030335 172 0.013
response to lipid GO:0033993 206 0.013
carbohydrate metabolic process GO:0005975 207 0.013
anion transport GO:0006820 161 0.013
negative regulation of jun kinase activity GO:0043508 4 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
regulation of cytokine production GO:0001817 232 0.012
tripartite regional subdivision GO:0007351 2 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
gtp metabolic process GO:0046039 239 0.012
angiogenesis GO:0001525 147 0.012
positive regulation of mitotic cell cycle GO:0045931 60 0.012
metal ion homeostasis GO:0055065 169 0.012
cell substrate adhesion GO:0031589 132 0.012
endomembrane system organization GO:0010256 196 0.012
response to inorganic substance GO:0010035 127 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
oocyte development GO:0048599 1 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
tube development GO:0035295 125 0.012
Human
regulation of protein processing GO:0070613 150 0.012
tissue morphogenesis GO:0048729 96 0.012
Human
cellular response to organic cyclic compound GO:0071407 127 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
neuron projection development GO:0031175 106 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
negative regulation of cell cycle GO:0045786 193 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
leukocyte differentiation GO:0002521 98 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
cell morphogenesis involved in differentiation GO:0000904 144 0.012
methylation GO:0032259 106 0.012
embryo development GO:0009790 123 0.012
anterior posterior axis specification GO:0009948 2 0.012
ossification GO:0001503 121 0.012
response to bacterium GO:0009617 144 0.012
spermatid development GO:0007286 4 0.012
myeloid leukocyte differentiation GO:0002573 60 0.012
associative learning GO:0008306 1 0.012
central nervous system development GO:0007417 123 0.012
chemotaxis GO:0006935 157 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
rna processing GO:0006396 255 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
response to tumor necrosis factor GO:0034612 76 0.012
protein localization to nucleus GO:0034504 136 0.012
protein secretion GO:0009306 98 0.012
positive regulation of immune response GO:0050778 159 0.012
nerve development GO:0021675 4 0.012
regulation of viral process GO:0050792 103 0.011
negative regulation of organelle organization GO:0010639 126 0.011
response to salt stress GO:0009651 3 0.011
cellular cation homeostasis GO:0030003 163 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
cellular response to external stimulus GO:0071496 111 0.011
cellular response to lipid GO:0071396 127 0.011
response to nitrogen compound GO:1901698 184 0.011
actin filament based movement GO:0030048 17 0.011
protein acylation GO:0043543 138 0.011
positive regulation of locomotion GO:0040017 186 0.011
osteoclast development GO:0036035 2 0.011
autophagy GO:0006914 88 0.011
spinal cord development GO:0021510 4 0.011
regulation of dna metabolic process GO:0051052 153 0.011
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
response to hormone GO:0009725 175 0.011
response to calcium ion GO:0051592 46 0.011
regulation of protein complex assembly GO:0043254 147 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
response to fungus GO:0009620 4 0.011
pattern specification process GO:0007389 43 0.011
divalent metal ion transport GO:0070838 152 0.011
primary neural tube formation GO:0014020 3 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
somitogenesis GO:0001756 2 0.011
positive regulation of vesicle fusion GO:0031340 4 0.011
neural nucleus development GO:0048857 47 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
cellular protein complex assembly GO:0043623 188 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
neural tube closure GO:0001843 3 0.011
regulation of protein maturation GO:1903317 150 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
organelle fission GO:0048285 149 0.011
protein modification by small protein removal GO:0070646 92 0.011
vesicle organization GO:0016050 62 0.011
Human
negative regulation of interleukin 1 mediated signaling pathway GO:2000660 2 0.011
protein processing GO:0016485 226 0.011
regulation of cell development GO:0060284 161 0.011
neurological system process GO:0050877 163 0.011
visual behavior GO:0007632 2 0.010
defense response to bacterium GO:0042742 63 0.010
protein import GO:0017038 130 0.010
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.010
negative regulation of locomotion GO:0040013 118 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
positive regulation of gtp catabolic process GO:0033126 166 0.010
protein methylation GO:0006479 74 0.010
regulation of cell adhesion GO:0030155 166 0.010
peptidyl tyrosine modification GO:0018212 170 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
single organism cell adhesion GO:0098602 179 0.010
organelle assembly GO:0070925 176 0.010
negative regulation of protein processing GO:0010955 142 0.010
protein deubiquitination GO:0016579 79 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
rhythmic behavior GO:0007622 2 0.010
regulation of vasculature development GO:1901342 97 0.010
regulation of mitotic cell cycle phase transition GO:1901990 118 0.010
heart development GO:0007507 95 0.010
regulation of map kinase activity GO:0043405 108 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
regulation of ion transport GO:0043269 189 0.010
cell growth GO:0016049 160 0.010
cell projection assembly GO:0030031 126 0.010
negative regulation of protein maturation GO:1903318 142 0.010
membrane fusion GO:0061025 43 0.010
nucleoside monophosphate metabolic process GO:0009123 191 0.010
anterior posterior axis specification embryo GO:0008595 2 0.010
inner ear morphogenesis GO:0042472 4 0.010
sulfur compound metabolic process GO:0006790 101 0.010
nuclear import GO:0051170 106 0.010
regulation of dephosphorylation GO:0035303 96 0.010
regulation of gtp catabolic process GO:0033124 180 0.010
response to light stimulus GO:0009416 87 0.010

KLHL23 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.025
nervous system disease DOID:863 431 0.021
sensory system disease DOID:0050155 203 0.021
cancer DOID:162 167 0.020
organ system cancer DOID:0050686 164 0.020
disease of cellular proliferation DOID:14566 174 0.020
disease of metabolism DOID:0014667 295 0.019
connective tissue disease DOID:65 109 0.017
bone disease DOID:0080001 88 0.017
central nervous system disease DOID:331 186 0.015
immune system disease DOID:2914 155 0.013
eye and adnexa disease DOID:1492 150 0.010
retinal disease DOID:5679 118 0.010
eye disease DOID:5614 149 0.010