Homo sapiens

34 known processes

PCGF1

polycomb group ring finger 1

(Aliases: MGC10882,RNF68,RNF3A-2,NSPC1,2010002K04Rik,FLJ43754)

PCGF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone h2a monoubiquitination GO:0035518 11 0.978
histone h2a ubiquitination GO:0033522 17 0.959
histone ubiquitination GO:0016574 31 0.812
protein monoubiquitination GO:0006513 39 0.616
regulation of odontogenesis GO:0042481 4 0.613
regulation of axon guidance GO:1902667 3 0.554
histone monoubiquitination GO:0010390 20 0.478
chromatin organization GO:0006325 351 0.425
histone modification GO:0016570 251 0.421
protein modification by small protein conjugation GO:0032446 342 0.389
protein ubiquitination GO:0016567 314 0.341
chromatin modification GO:0016568 298 0.311
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.293
Human
covalent chromatin modification GO:0016569 254 0.277
regulation of tooth mineralization GO:0070170 3 0.188
regulation of axon extension involved in axon guidance GO:0048841 2 0.162
blastoderm segmentation GO:0007350 2 0.139
biomineral tissue development GO:0031214 39 0.134
bone mineralization GO:0030282 34 0.129
specification of axis polarity GO:0065001 1 0.123
organ morphogenesis GO:0009887 147 0.104
odontogenesis GO:0042476 25 0.098
regulation of biomineral tissue development GO:0070167 31 0.095
negative regulation of biomineral tissue development GO:0070168 8 0.093
macromolecule methylation GO:0043414 97 0.085
negative regulation of programmed cell death GO:0043069 321 0.066
neuron remodeling GO:0016322 2 0.061
regulation of transferase activity GO:0051338 355 0.060
Human
post embryonic development GO:0009791 2 0.058
negative regulation of cellular component organization GO:0051129 235 0.055
response to abiotic stimulus GO:0009628 336 0.053
segmentation GO:0035282 4 0.053
regulation of ossification GO:0030278 58 0.052
nervous system development GO:0007399 293 0.051
negative regulation of developmental process GO:0051093 247 0.050
response to ionizing radiation GO:0010212 65 0.049
hindbrain development GO:0030902 3 0.049
negative regulation of ossification GO:0030279 21 0.049
hematopoietic or lymphoid organ development GO:0048534 186 0.047
Human
methylation GO:0032259 106 0.046
negative regulation of organelle organization GO:0010639 126 0.044
negative regulation of chromosome organization GO:2001251 48 0.043
protein alkylation GO:0008213 74 0.041
response to radiation GO:0009314 151 0.040
histone h3 k27 demethylation GO:0071557 3 0.040
fibroblast proliferation GO:0048144 33 0.039
Human
gastrulation with mouth forming second GO:0001702 1 0.039
histone h3 k4 methylation GO:0051568 27 0.038
morphogenesis of embryonic epithelium GO:0016331 4 0.038
response to oxygen containing compound GO:1901700 369 0.037
multicellular organismal aging GO:0010259 3 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
positive regulation of transferase activity GO:0051347 227 0.036
Human
protein methylation GO:0006479 74 0.036
regulation of gene expression epigenetic GO:0040029 73 0.036
wound healing GO:0042060 115 0.035
regulation of cellular amine metabolic process GO:0033238 11 0.035
response to gamma radiation GO:0010332 14 0.035
cellular macromolecule catabolic process GO:0044265 380 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
amine metabolic process GO:0009308 44 0.034
embryonic camera type eye morphogenesis GO:0048596 2 0.033
anterior posterior axis specification GO:0009948 2 0.033
negative regulation of protein modification process GO:0031400 200 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
tooth mineralization GO:0034505 6 0.032
cell morphogenesis GO:0000902 296 0.032
cardiovascular system development GO:0072358 262 0.032
embryonic eye morphogenesis GO:0048048 2 0.032
sister chromatid cohesion GO:0007062 24 0.032
regulation of multi organism process GO:0043900 157 0.032
cellular amino acid metabolic process GO:0006520 116 0.032
ossification GO:0001503 121 0.031
histone methylation GO:0016571 60 0.031
spinal cord development GO:0021510 4 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
positive regulation of ligase activity GO:0051351 19 0.030
Human
rostrocaudal neural tube patterning GO:0021903 1 0.029
cellular ketone metabolic process GO:0042180 80 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
regulation of neural precursor cell proliferation GO:2000177 4 0.027
negative regulation of cell death GO:0060548 345 0.027
primary neural tube formation GO:0014020 3 0.027
gene silencing GO:0016458 49 0.027
mitotic cell cycle GO:0000278 326 0.027
histone demethylation GO:0016577 15 0.027
response to wounding GO:0009611 168 0.027
immune response GO:0006955 307 0.026
generation of neurons GO:0048699 152 0.026
transmembrane transport GO:0055085 399 0.026
regulation of cellular component movement GO:0051270 334 0.026
negative regulation of chromatin modification GO:1903309 21 0.026
female gamete generation GO:0007292 2 0.026
locomotory behavior GO:0007626 1 0.025
cellular amine metabolic process GO:0044106 41 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.025
innate immune response GO:0045087 178 0.025
eye morphogenesis GO:0048592 16 0.025
regulation of chromatin organization GO:1902275 56 0.025
chromosome segregation GO:0007059 114 0.025
regionalization GO:0003002 29 0.025
neuron development GO:0048666 113 0.024
positive regulation of immune system process GO:0002684 283 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.024
Human
regulation of locomotion GO:0040012 329 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.023
neurogenesis GO:0022008 169 0.023
negative regulation of odontogenesis GO:0042483 1 0.023
histone lysine demethylation GO:0070076 14 0.022
vesicle mediated transport GO:0016192 371 0.022
regulation of chromosome organization GO:0033044 103 0.022
tube morphogenesis GO:0035239 95 0.022
epithelium development GO:0060429 227 0.022
intrinsic apoptotic signaling pathway GO:0097193 127 0.022
regulation of cell migration GO:0030334 289 0.022
regulation of cytokine production GO:0001817 232 0.022
neural tube formation GO:0001841 3 0.021
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
regulation of cell projection organization GO:0031344 107 0.021
cell projection organization GO:0030030 252 0.021
oogenesis GO:0048477 2 0.021
defense response GO:0006952 315 0.021
embryo development GO:0009790 123 0.021
palate development GO:0060021 13 0.021
regulation of organ morphogenesis GO:2000027 24 0.020
neural tube patterning GO:0021532 2 0.020
membrane organization GO:0061024 292 0.020
circulatory system development GO:0072359 262 0.020
sensory organ development GO:0007423 52 0.020
apoptotic signaling pathway GO:0097190 268 0.020
cation transport GO:0006812 331 0.020
negative regulation of gene expression epigenetic GO:0045814 19 0.020
negative regulation of histone modification GO:0031057 19 0.020
negative regulation of cell proliferation GO:0008285 228 0.019
sensory organ morphogenesis GO:0090596 21 0.019
regulation of histone modification GO:0031056 47 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
regulation of proteolysis GO:0030162 293 0.019
regulation of neuron differentiation GO:0045664 70 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
ion transmembrane transport GO:0034220 338 0.018
cell growth GO:0016049 160 0.018
negative regulation of chromatin silencing GO:0031936 4 0.018
mitotic cell cycle process GO:1903047 286 0.018
regulation of protein kinase activity GO:0045859 289 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
pattern specification process GO:0007389 43 0.018
regulation of response to external stimulus GO:0032101 222 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
rna splicing GO:0008380 131 0.018
spermatid differentiation GO:0048515 4 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
cellular component morphogenesis GO:0032989 314 0.017
growth GO:0040007 202 0.017
regulation of behavior GO:0050795 82 0.017
tube development GO:0035295 125 0.017
response to lipid GO:0033993 206 0.017
regulation of neuron projection development GO:0010975 57 0.017
nucleotide catabolic process GO:0009166 408 0.017
regeneration GO:0031099 4 0.017
protein catabolic process GO:0030163 325 0.017
single organism membrane organization GO:0044802 268 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
hemopoiesis GO:0030097 180 0.016
Human
cytokine production GO:0001816 247 0.016
cellular lipid metabolic process GO:0044255 303 0.016
endocytosis GO:0006897 159 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
embryonic organ development GO:0048568 36 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
engulfment of apoptotic cell GO:0043652 2 0.016
lipid metabolic process GO:0006629 381 0.016
positive regulation of transport GO:0051050 336 0.016
response to inorganic substance GO:0010035 127 0.016
regulation of cell motility GO:2000145 299 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
calcium ion transport GO:0006816 147 0.015
mating GO:0007618 1 0.015
divalent metal ion transport GO:0070838 152 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
positive regulation of cell death GO:0010942 263 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
regulation of immune response GO:0050776 201 0.015
adult locomotory behavior GO:0008344 1 0.014
cation transmembrane transport GO:0098655 238 0.014
secretion by cell GO:0032940 226 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
system process GO:0003008 349 0.014
regulation of kinase activity GO:0043549 314 0.014
regulation of chromatin modification GO:1903308 51 0.014
chemical homeostasis GO:0048878 306 0.014
cell cycle phase transition GO:0044770 173 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
reproductive process GO:0022414 106 0.014
cellular homeostasis GO:0019725 196 0.014
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.014
Human
neuron projection extension involved in neuron projection guidance GO:1902284 5 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
modification dependent protein catabolic process GO:0019941 209 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.013
regulation of histone methylation GO:0031060 16 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
single organism cellular localization GO:1902580 332 0.013
regulation of peptidase activity GO:0052547 180 0.013
interspecies interaction between organisms GO:0044419 156 0.013
embryonic morphogenesis GO:0048598 85 0.013
heart development GO:0007507 95 0.013
oocyte differentiation GO:0009994 2 0.013
protein demethylation GO:0006482 17 0.013
regulation of neurogenesis GO:0050767 82 0.013
response to cytokine GO:0034097 232 0.013
protein oligomerization GO:0051259 173 0.013
divalent inorganic cation transport GO:0072511 158 0.013
maintenance of location GO:0051235 112 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
secretion GO:0046903 254 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
regulation of protein localization GO:0032880 296 0.012
response to external biotic stimulus GO:0043207 261 0.012
immune effector process GO:0002252 159 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
neuron differentiation GO:0030182 138 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
dephosphorylation GO:0016311 209 0.012
mitochondrion organization GO:0007005 156 0.012
histone h3 k36 demethylation GO:0070544 5 0.012
organophosphate catabolic process GO:0046434 430 0.012
neurotransmitter secretion GO:0007269 4 0.012
associative learning GO:0008306 1 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
rho protein signal transduction GO:0007266 26 0.012
ion homeostasis GO:0050801 230 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
metal ion transport GO:0030001 272 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
protein maturation GO:0051604 233 0.012
cell development GO:0048468 328 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
taxis GO:0042330 157 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
cytoplasmic transport GO:0016482 379 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
rhythmic behavior GO:0007622 2 0.012
sequestering of metal ion GO:0051238 24 0.012
positive regulation of catabolic process GO:0009896 310 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
axon extension involved in axon guidance GO:0048846 5 0.012
spermatid development GO:0007286 4 0.012
positive regulation of cytokine production GO:0001819 167 0.012
neuromuscular junction development GO:0007528 3 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
cellular protein complex assembly GO:0043623 188 0.011
dna repair GO:0006281 198 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
response to axon injury GO:0048678 1 0.011
oxidation reduction process GO:0055114 396 0.011
regulation of protein transport GO:0051223 213 0.011
rna interference GO:0016246 4 0.011
purine containing compound catabolic process GO:0072523 411 0.011
protein localization to organelle GO:0033365 280 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
lens development in camera type eye GO:0002088 2 0.011
t cell differentiation in thymus GO:0033077 4 0.011
positive regulation of cell motility GO:2000147 177 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
regulation of cell growth GO:0001558 135 0.011
multi organism cellular process GO:0044764 156 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
cell division GO:0051301 168 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
positive regulation of organelle organization GO:0010638 195 0.011
actin filament based process GO:0030029 224 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
circadian behavior GO:0048512 2 0.011
regulation of ion transmembrane transport GO:0034765 132 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
small molecule biosynthetic process GO:0044283 157 0.011
oocyte development GO:0048599 1 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
embryonic camera type eye development GO:0031076 2 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
determination of adult lifespan GO:0008340 2 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
response to acid chemical GO:0001101 66 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
protein deubiquitination GO:0016579 79 0.011
single organism reproductive process GO:0044702 98 0.011
sequestering of calcium ion GO:0051208 17 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
regulation of growth GO:0040008 165 0.010
metal ion homeostasis GO:0055065 169 0.010
cell adhesion GO:0007155 325 0.010
ribonucleotide catabolic process GO:0009261 405 0.010
purine ribonucleoside metabolic process GO:0046128 437 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
protein processing GO:0016485 226 0.010
regulation of cell development GO:0060284 161 0.010
peptidyl lysine modification GO:0018205 144 0.010
regulation of cell cycle GO:0051726 393 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010
nucleoside phosphate catabolic process GO:1901292 412 0.010
regulation of dna metabolic process GO:0051052 153 0.010
visual behavior GO:0007632 2 0.010

PCGF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.376
nervous system disease DOID:863 431 0.376
eye and adnexa disease DOID:1492 150 0.355
eye disease DOID:5614 149 0.355
microphthalmia DOID:10629 11 0.055
musculoskeletal system disease DOID:17 223 0.017
disease of metabolism DOID:0014667 295 0.017
central nervous system disease DOID:331 186 0.014
disease of cellular proliferation DOID:14566 174 0.014
retinal disease DOID:5679 118 0.013
immune system disease DOID:2914 155 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
connective tissue disease DOID:65 109 0.012
cancer DOID:162 167 0.011
organ system cancer DOID:0050686 164 0.010
inherited metabolic disorder DOID:655 242 0.010
neurodegenerative disease DOID:1289 102 0.010