Homo sapiens

31 known processes

SMO

smoothened homolog (Drosophila)

(Aliases: SMOH,Gx)

SMO biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ morphogenesis GO:0009887 147 0.701
Zebrafish Fly
neural tube patterning GO:0021532 2 0.559
oogenesis GO:0048477 2 0.519
Fly
epithelium development GO:0060429 227 0.497
Zebrafish Fly
urogenital system development GO:0001655 65 0.476
chemotaxis GO:0006935 157 0.421
Zebrafish Rat
taxis GO:0042330 157 0.411
Zebrafish Rat
negative regulation of smoothened signaling pathway GO:0045879 3 0.410
tube development GO:0035295 125 0.403
Zebrafish
female gamete generation GO:0007292 2 0.394
Fly
negative regulation of developmental process GO:0051093 247 0.389
Fly
renal system development GO:0072001 63 0.381
cellular component morphogenesis GO:0032989 314 0.351
Zebrafish Rat
regulation of cell differentiation GO:0045595 393 0.327
Fly
membrane organization GO:0061024 292 0.291
Zebrafish Fly
regulation of establishment of protein localization GO:0070201 242 0.289
Fly
cell morphogenesis GO:0000902 296 0.257
Zebrafish Rat
endomembrane system organization GO:0010256 196 0.255
Fly
ossification GO:0001503 121 0.246
Rat
cell development GO:0048468 328 0.241
Zebrafish Rat Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.239
Zebrafish Rat
cell projection organization GO:0030030 252 0.226
Zebrafish Rat
negative regulation of multicellular organismal process GO:0051241 317 0.224
negative regulation of cell differentiation GO:0045596 171 0.208
Fly
protein localization to membrane GO:0072657 160 0.206
Zebrafish Fly
protein localization to plasma membrane GO:0072659 93 0.185
Fly
establishment of protein localization to plasma membrane GO:0090002 68 0.176
Fly
intracellular protein transport GO:0006886 270 0.173
organic hydroxy compound transport GO:0015850 63 0.165
regulation of protein transport GO:0051223 213 0.165
regulation of cellular component movement GO:0051270 334 0.158
single organism cellular localization GO:1902580 332 0.155
Zebrafish Fly
establishment of protein localization to membrane GO:0090150 121 0.154
Fly
pharyngeal system development GO:0060037 2 0.152
regulation of osteoblast differentiation GO:0045667 38 0.152
regulation of protein localization GO:0032880 296 0.152
Fly
nervous system development GO:0007399 293 0.145
Zebrafish Rat
cellular response to oxygen containing compound GO:1901701 276 0.143
regulation of mitotic cell cycle GO:0007346 189 0.143
Fly
regulation of locomotion GO:0040012 329 0.140
mitotic cell cycle GO:0000278 326 0.138
Fly
cytoplasmic transport GO:0016482 379 0.135
regulation of ossification GO:0030278 58 0.134
regionalization GO:0003002 29 0.133
Zebrafish Fly
cell projection morphogenesis GO:0048858 129 0.130
Zebrafish Rat
regulation of anatomical structure morphogenesis GO:0022603 286 0.127
nucleocytoplasmic transport GO:0006913 176 0.125
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.124
protein import GO:0017038 130 0.123
neuron differentiation GO:0030182 138 0.123
Zebrafish Rat
neural tube development GO:0021915 9 0.122
Zebrafish
segmentation GO:0035282 4 0.121
Fly
limb morphogenesis GO:0035108 16 0.120
cellular ketone metabolic process GO:0042180 80 0.119
sensory organ morphogenesis GO:0090596 21 0.118
Zebrafish Fly
embryonic morphogenesis GO:0048598 85 0.118
Zebrafish
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.115
pituitary gland development GO:0021983 2 0.115
Zebrafish
positive regulation of transport GO:0051050 336 0.114
single organism membrane organization GO:0044802 268 0.114
Zebrafish Fly
cholesterol efflux GO:0033344 28 0.112
sterol transport GO:0015918 39 0.112
motor neuron axon guidance GO:0008045 2 0.111
limb development GO:0060173 23 0.111
regulation of cell motility GO:2000145 299 0.110
smoothened signaling pathway GO:0007224 14 0.106
protein localization to organelle GO:0033365 280 0.104
response to lipid GO:0033993 206 0.102
lipid transport GO:0006869 90 0.102
amine metabolic process GO:0009308 44 0.102
neurogenesis GO:0022008 169 0.101
Zebrafish Rat
ras protein signal transduction GO:0007265 73 0.100
morphogenesis of embryonic epithelium GO:0016331 4 0.100
Zebrafish
nuclear transport GO:0051169 179 0.100
circulatory system development GO:0072359 262 0.100
Zebrafish
nuclear import GO:0051170 106 0.099
spinal cord development GO:0021510 4 0.096
Zebrafish
organ formation GO:0048645 3 0.096
cellular amino acid metabolic process GO:0006520 116 0.095
regulation of cell migration GO:0030334 289 0.095
cholesterol transport GO:0030301 39 0.095
biological adhesion GO:0022610 331 0.095
response to oxygen containing compound GO:1901700 369 0.094
positive regulation of developmental process GO:0051094 314 0.093
chemical homeostasis GO:0048878 306 0.093
cellular response to lipid GO:0071396 127 0.090
neuron development GO:0048666 113 0.090
Zebrafish Rat
regulation of cellular amine metabolic process GO:0033238 11 0.088
regulation of intracellular transport GO:0032386 195 0.088
regulation of cellular amino acid metabolic process GO:0006521 6 0.086
actin filament based process GO:0030029 224 0.084
Zebrafish
regulation of intracellular protein transport GO:0033157 123 0.079
regulation of cytoplasmic transport GO:1903649 149 0.079
positive regulation of cellular component movement GO:0051272 181 0.079
response to growth factor GO:0070848 205 0.078
organophosphate catabolic process GO:0046434 430 0.078
retinal ganglion cell axon guidance GO:0031290 2 0.078
Zebrafish
rho protein signal transduction GO:0007266 26 0.078
embryo development GO:0009790 123 0.075
Zebrafish Fly
eye morphogenesis GO:0048592 16 0.075
Fly
protein targeting GO:0006605 187 0.075
regulation of protein localization to nucleus GO:1900180 85 0.072
positive regulation of locomotion GO:0040017 186 0.072
skeletal system development GO:0001501 79 0.072
Zebrafish
regulation of nucleocytoplasmic transport GO:0046822 98 0.071
positive regulation of cellular component organization GO:0051130 376 0.069
Fly
cellular response to organic cyclic compound GO:0071407 127 0.068
somite development GO:0061053 7 0.068
glycosyl compound catabolic process GO:1901658 413 0.067
regulation of protein import into nucleus GO:0042306 78 0.067
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.067
cell part morphogenesis GO:0032990 137 0.067
Zebrafish Rat
eye development GO:0001654 42 0.067
Zebrafish Fly
sensory organ development GO:0007423 52 0.067
Zebrafish Fly
cellular response to endogenous stimulus GO:0071495 336 0.066
protein targeting to nucleus GO:0044744 104 0.065
protein import into nucleus GO:0006606 104 0.065
regulation of gtp catabolic process GO:0033124 180 0.064
digestive system development GO:0055123 75 0.063
Zebrafish
ribonucleoside catabolic process GO:0042454 406 0.063
positive regulation of cell proliferation GO:0008284 301 0.063
hindbrain development GO:0030902 3 0.063
Zebrafish
ameboidal type cell migration GO:0001667 135 0.063
purine nucleoside catabolic process GO:0006152 398 0.062
anatomical structure formation involved in morphogenesis GO:0048646 284 0.061
Zebrafish
post embryonic development GO:0009791 2 0.061
Fly
regulation of cell cycle process GO:0010564 266 0.061
Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.060
canonical wnt signaling pathway GO:0060070 116 0.060
regulation of protein targeting GO:1903533 91 0.059
vasculature development GO:0001944 181 0.059
Zebrafish
tissue morphogenesis GO:0048729 96 0.059
Zebrafish
vesicle mediated transport GO:0016192 371 0.059
protein localization to nucleus GO:0034504 136 0.058
enzyme linked receptor protein signaling pathway GO:0007167 303 0.058
single organism nuclear import GO:1902593 104 0.057
positive regulation of cell motility GO:2000147 177 0.057
nucleoside triphosphate catabolic process GO:0009143 394 0.057
purine ribonucleotide catabolic process GO:0009154 404 0.056
nucleoside catabolic process GO:0009164 408 0.056
regulation of nucleotide metabolic process GO:0006140 269 0.055
purine nucleoside triphosphate catabolic process GO:0009146 392 0.055
multicellular organismal aging GO:0010259 3 0.055
nerve development GO:0021675 4 0.055
Rat
regulation of cell cycle GO:0051726 393 0.054
Fly
negative regulation of protein metabolic process GO:0051248 391 0.054
system process GO:0003008 349 0.054
lipid localization GO:0010876 106 0.053
regeneration GO:0031099 4 0.053
Rat
cell adhesion GO:0007155 325 0.053
small gtpase mediated signal transduction GO:0007264 78 0.053
epithelial cell differentiation GO:0030855 141 0.052
Zebrafish Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.052
regulation of cellular ketone metabolic process GO:0010565 50 0.052
neuron fate commitment GO:0048663 2 0.052
Zebrafish
axonogenesis GO:0007409 31 0.052
Zebrafish Rat
ribonucleoside triphosphate catabolic process GO:0009203 391 0.051
positive regulation of cellular amine metabolic process GO:0033240 7 0.050
regulation of cellular component biogenesis GO:0044087 281 0.050
reproductive process GO:0022414 106 0.050
Rat Fly
negative regulation of ossification GO:0030279 21 0.050
determination of adult lifespan GO:0008340 2 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
blood vessel development GO:0001568 172 0.050
Zebrafish
cartilage condensation GO:0001502 1 0.050
regulation of hormone levels GO:0010817 125 0.049
cell differentiation in spinal cord GO:0021515 1 0.049
Zebrafish
mapk cascade GO:0000165 288 0.049
blood vessel morphogenesis GO:0048514 162 0.049
Zebrafish
axon development GO:0061564 34 0.049
Zebrafish Rat
neuron projection morphogenesis GO:0048812 50 0.049
Zebrafish Rat
purine ribonucleoside metabolic process GO:0046128 437 0.048
response to organic cyclic compound GO:0014070 204 0.048
cell aggregation GO:0098743 1 0.047
regulation of response to external stimulus GO:0032101 222 0.047
signal transduction by phosphorylation GO:0023014 297 0.046
guanosine containing compound catabolic process GO:1901069 239 0.046
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
digestive tract development GO:0048565 75 0.045
Zebrafish
epithelium migration GO:0090132 119 0.045
endocytosis GO:0006897 159 0.045
regulation of sterol transport GO:0032371 21 0.044
regulation of purine nucleotide catabolic process GO:0033121 205 0.044
single organism reproductive process GO:0044702 98 0.044
Rat Fly
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.043
Zebrafish Rat
blastoderm segmentation GO:0007350 2 0.043
Fly
gtp catabolic process GO:0006184 237 0.043
cellular response to cholesterol GO:0071397 4 0.043
formation of primary germ layer GO:0001704 42 0.043
negative regulation of cell proliferation GO:0008285 228 0.043
cellular response to growth factor stimulus GO:0071363 197 0.043
negative regulation of locomotion GO:0040013 118 0.042
nucleotide catabolic process GO:0009166 408 0.042
regulation of mapk cascade GO:0043408 262 0.042
single organism cell adhesion GO:0098602 179 0.042
positive regulation of nucleoside metabolic process GO:0045979 186 0.042
axon guidance GO:0007411 12 0.042
Zebrafish Rat
cellular amine metabolic process GO:0044106 41 0.042
skin development GO:0043588 76 0.041
purine containing compound catabolic process GO:0072523 411 0.041
generation of neurons GO:0048699 152 0.041
Zebrafish Rat
positive regulation of nucleotide metabolic process GO:0045981 230 0.040
oocyte development GO:0048599 1 0.040
actin cytoskeleton organization GO:0030036 207 0.040
Zebrafish
response to cholesterol GO:0070723 11 0.039
carbohydrate derivative biosynthetic process GO:1901137 207 0.039
negative regulation of cell death GO:0060548 345 0.039
ribonucleotide catabolic process GO:0009261 405 0.039
regulation of canonical wnt signaling pathway GO:0060828 88 0.038
endodermal cell fate commitment GO:0001711 4 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.038
neuron projection development GO:0031175 106 0.038
Zebrafish Rat
cell growth GO:0016049 160 0.038
Rat
embryonic epithelial tube formation GO:0001838 4 0.038
negative regulation of phosphate metabolic process GO:0045936 267 0.038
wnt signaling pathway GO:0016055 156 0.038
morphogenesis of an epithelium GO:0002009 60 0.038
Zebrafish
negative regulation of catalytic activity GO:0043086 335 0.037
regulation of cell growth GO:0001558 135 0.037
negative regulation of phosphorus metabolic process GO:0010563 267 0.037
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
cellular response to dna damage stimulus GO:0006974 379 0.036
forelimb morphogenesis GO:0035136 4 0.036
positive regulation of cell death GO:0010942 263 0.036
endodermal cell fate specification GO:0001714 4 0.036
regulation of gtpase activity GO:0043087 180 0.036
guanosine containing compound metabolic process GO:1901068 244 0.036
regulation of cell development GO:0060284 161 0.036
regulation of cellular response to stress GO:0080135 244 0.036
connective tissue development GO:0061448 39 0.035
Zebrafish
muscle structure development GO:0061061 98 0.035
Zebrafish
transmembrane transport GO:0055085 399 0.035
osteoblast differentiation GO:0001649 92 0.035
Rat
embryonic forelimb morphogenesis GO:0035115 4 0.035
cell substrate adhesion GO:0031589 132 0.035
neural tube formation GO:0001841 3 0.034
plasma membrane organization GO:0007009 115 0.034
Fly
cardiovascular system development GO:0072358 262 0.034
Zebrafish
oocyte differentiation GO:0009994 2 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
endothelial cell migration GO:0043542 86 0.034
purine nucleotide catabolic process GO:0006195 405 0.034
positive regulation of apoptotic process GO:0043065 246 0.033
prostate gland development GO:0030850 3 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.033
regulation of smoothened signaling pathway GO:0008589 6 0.033
Zebrafish
reactive oxygen species metabolic process GO:0072593 75 0.033
mitotic cell cycle process GO:1903047 286 0.033
Fly
stem cell differentiation GO:0048863 93 0.033
Zebrafish Fly
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.032
cell cell signaling GO:0007267 155 0.032
locomotory behavior GO:0007626 1 0.032
developmental process involved in reproduction GO:0003006 66 0.032
Fly
protein targeting to membrane GO:0006612 42 0.032
metencephalon development GO:0022037 2 0.032
Zebrafish
negative regulation of cellular component movement GO:0051271 106 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
cardiac muscle cell contraction GO:0086003 4 0.032
negative regulation of apoptotic process GO:0043066 316 0.032
lipid homeostasis GO:0055088 39 0.031
endoderm formation GO:0001706 33 0.031
response to wounding GO:0009611 168 0.031
Rat
immune response GO:0006955 307 0.031
regulation of nucleoside metabolic process GO:0009118 209 0.031
cranial nerve development GO:0021545 4 0.031
Rat
cellular response to alcohol GO:0097306 29 0.031
regulation of cell adhesion GO:0030155 166 0.031
regulation of axon guidance GO:1902667 3 0.031
brain development GO:0007420 97 0.031
Zebrafish
cdc42 protein signal transduction GO:0032488 4 0.031
gland development GO:0048732 48 0.031
Zebrafish
cell fate determination GO:0001709 3 0.031
cell matrix adhesion GO:0007160 85 0.030
regulation of nucleotide catabolic process GO:0030811 205 0.030
positive regulation of nucleotide catabolic process GO:0030813 185 0.030
regulation of cytoskeleton organization GO:0051493 177 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.030
ion transmembrane transport GO:0034220 338 0.029
epidermis morphogenesis GO:0048730 3 0.029
glial cell migration GO:0008347 4 0.029
somatic stem cell maintenance GO:0035019 4 0.029
Fly
kidney development GO:0001822 53 0.029
regulation of male gonad development GO:2000018 4 0.029
epithelial cell migration GO:0010631 119 0.029
regulation of lipid transport GO:0032368 44 0.028
reproductive system development GO:0061458 56 0.028
positive regulation of cell cycle GO:0045787 140 0.028
epithelial tube morphogenesis GO:0060562 38 0.028
Zebrafish
negative regulation of gliogenesis GO:0014014 3 0.028
peripheral nervous system development GO:0007422 2 0.028
positive regulation of gtp catabolic process GO:0033126 166 0.027
angiogenesis GO:0001525 147 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
positive regulation of odontogenesis GO:0042482 3 0.027
microtubule based process GO:0007017 210 0.027
regulation of secretion GO:0051046 194 0.027
lipid metabolic process GO:0006629 381 0.027
regulation of proteolysis GO:0030162 293 0.027
stem cell development GO:0048864 69 0.026
Fly
embryonic skeletal joint development GO:0072498 2 0.026
regulation of wnt signaling pathway GO:0030111 123 0.026
response to alcohol GO:0097305 64 0.026
hindlimb morphogenesis GO:0035137 2 0.026
ion homeostasis GO:0050801 230 0.026
chromatin organization GO:0006325 351 0.026
muscle cell fate commitment GO:0042693 4 0.026
Zebrafish
regulation of actin filament based process GO:0032970 141 0.026
epidermis development GO:0008544 59 0.025
digestive tract morphogenesis GO:0048546 56 0.025
Zebrafish
regulation of actin cytoskeleton organization GO:0032956 116 0.025
protein maturation GO:0051604 233 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
neuromuscular junction development GO:0007528 3 0.025
response to sterol GO:0036314 14 0.025
chromatin modification GO:0016568 298 0.025
regulation of nervous system development GO:0051960 88 0.025
nitrogen compound transport GO:0071705 191 0.025
regulation of stem cell differentiation GO:2000736 56 0.025
pattern specification process GO:0007389 43 0.025
Zebrafish Fly
stem cell division GO:0017145 2 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
prostate gland morphogenesis GO:0060512 1 0.025
negative regulation of cell cycle GO:0045786 193 0.025
Fly
positive regulation of lipid transport GO:0032370 22 0.025
heart morphogenesis GO:0003007 48 0.024
Zebrafish
regulation of reactive oxygen species metabolic process GO:2000377 41 0.024
posttranscriptional regulation of gene expression GO:0010608 213 0.024
hair follicle morphogenesis GO:0031069 2 0.024
mesonephric duct development GO:0072177 3 0.024
regulation of cell substrate adhesion GO:0010810 68 0.024
dermatome development GO:0061054 3 0.024
regulation of vasculature development GO:1901342 97 0.024
negative regulation of phosphorylation GO:0042326 174 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
gtp metabolic process GO:0046039 239 0.024
positive regulation of cell migration GO:0030335 172 0.024
regulation of growth GO:0040008 165 0.023
regulation of cell morphogenesis GO:0022604 153 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.023
heart formation GO:0060914 2 0.023
salivary gland morphogenesis GO:0007435 4 0.023
response to abiotic stimulus GO:0009628 336 0.023
anterior posterior axis specification GO:0009948 2 0.023
cloacal septation GO:0060197 1 0.023
immune system development GO:0002520 195 0.023
immune effector process GO:0002252 159 0.023
secretion by cell GO:0032940 226 0.023
embryo development ending in birth or egg hatching GO:0009792 34 0.023
Zebrafish
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.023
positive regulation of cell development GO:0010720 92 0.022
forebrain regionalization GO:0021871 3 0.022
Zebrafish
specification of organ identity GO:0010092 3 0.022
regulation of neurogenesis GO:0050767 82 0.022
regulation of keratinocyte migration GO:0051547 4 0.022
negative regulation of cell migration GO:0030336 102 0.022
endochondral bone morphogenesis GO:0060350 3 0.022
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.022
regulation of ras gtpase activity GO:0032318 128 0.022
somitogenesis GO:0001756 2 0.022
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.022
positive regulation of gtpase activity GO:0043547 166 0.022
multi organism reproductive process GO:0044703 54 0.021
Rat Fly
appendage development GO:0048736 23 0.021
Zebrafish
primary neural tube formation GO:0014020 3 0.021
small molecule biosynthetic process GO:0044283 157 0.021
positive regulation of cortisol biosynthetic process GO:2000066 1 0.021
central nervous system development GO:0007417 123 0.021
Zebrafish Rat
embryonic hindlimb morphogenesis GO:0035116 2 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
glycoprotein metabolic process GO:0009100 110 0.021
regulation of epithelial cell proliferation GO:0050678 113 0.021
sex differentiation GO:0007548 45 0.021
regulation of axon extension involved in axon guidance GO:0048841 2 0.021
positive regulation of dermatome development GO:0061184 3 0.021
circulatory system process GO:0003013 113 0.021
positive regulation of immune system process GO:0002684 283 0.021
skeletal system morphogenesis GO:0048705 24 0.021
Zebrafish
regulation of cell cell adhesion GO:0022407 57 0.021
cellular lipid metabolic process GO:0044255 303 0.021
negative regulation of cell motility GO:2000146 104 0.021
cation transmembrane transport GO:0098655 238 0.021
protein ubiquitination GO:0016567 314 0.021
regulation of rho gtpase activity GO:0032319 66 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
compound eye development GO:0048749 1 0.020
reproductive structure development GO:0048608 55 0.020
cell junction organization GO:0034330 79 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
wound healing GO:0042060 115 0.020
protein catabolic process GO:0030163 325 0.020
regulation of transferase activity GO:0051338 355 0.020
cellular metal ion homeostasis GO:0006875 146 0.020
actin mediated cell contraction GO:0070252 12 0.020
blood circulation GO:0008015 113 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
axon regeneration GO:0031103 1 0.020
reproduction GO:0000003 63 0.020
Rat Fly
adult locomotory behavior GO:0008344 1 0.020
inner ear morphogenesis GO:0042472 4 0.020
Zebrafish
tube closure GO:0060606 3 0.019
dephosphorylation GO:0016311 209 0.019
positive regulation of cell differentiation GO:0045597 211 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
limbic system development GO:0021761 3 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
Fly
positive regulation of aldosterone metabolic process GO:0032346 2 0.019
receptor mediated endocytosis GO:0006898 84 0.019
limb bud formation GO:0060174 1 0.019
oxidation reduction process GO:0055114 396 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
positive regulation of cell cycle process GO:0090068 106 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
response to axon injury GO:0048678 1 0.019
apoptotic signaling pathway GO:0097190 268 0.019
tripartite regional subdivision GO:0007351 2 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
tissue migration GO:0090130 119 0.019
gonad development GO:0008406 34 0.019
negative regulation of immune system process GO:0002683 136 0.019
histone modification GO:0016570 251 0.019
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
response to hormone GO:0009725 175 0.019
protein processing GO:0016485 226 0.019
multicellular organismal metabolic process GO:0044236 34 0.019
metal ion homeostasis GO:0055065 169 0.019
cell cycle phase transition GO:0044770 173 0.019
Fly
neuron projection regeneration GO:0031102 1 0.019
Rat
secretion GO:0046903 254 0.019
activation of immune response GO:0002253 114 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
multicellular organismal reproductive process GO:0048609 40 0.019
Rat Fly
morphogenesis of a polarized epithelium GO:0001738 3 0.018
negative regulation of protein modification process GO:0031400 200 0.018
neurological system process GO:0050877 163 0.018
cellular response to cytokine stimulus GO:0071345 181 0.018
neural crest cell development GO:0014032 3 0.018
response to other organism GO:0051707 261 0.018
regulation of binding GO:0051098 111 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
rhythmic behavior GO:0007622 2 0.018
tube morphogenesis GO:0035239 95 0.018
Zebrafish
stress activated protein kinase signaling cascade GO:0031098 94 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
melanin metabolic process GO:0006582 1 0.018
regulation of kinase activity GO:0043549 314 0.018
cell division GO:0051301 168 0.018
endoderm development GO:0007492 33 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
appendage morphogenesis GO:0035107 16 0.018
Zebrafish
response to external biotic stimulus GO:0043207 261 0.018
tissue regeneration GO:0042246 3 0.018
glycoprotein biosynthetic process GO:0009101 91 0.018
embryonic camera type eye development GO:0031076 2 0.018
Zebrafish
innate immune response GO:0045087 178 0.018
cardiac cell fate determination GO:0060913 3 0.018
cellular response to acid chemical GO:0071229 44 0.018
dna replication GO:0006260 116 0.018
response to biotic stimulus GO:0009607 276 0.018
divalent metal ion transport GO:0070838 152 0.018
mesenchymal cell differentiation GO:0048762 52 0.017
Zebrafish
kidney epithelium development GO:0072073 25 0.017
positive regulation of ras gtpase activity GO:0032320 117 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
positive regulation of keratinocyte migration GO:0051549 4 0.017
regulation of neuron differentiation GO:0045664 70 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.017
regulation of angiogenesis GO:0045765 92 0.017
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.017
anion transport GO:0006820 161 0.017
organic anion transport GO:0015711 103 0.017
cell projection assembly GO:0030031 126 0.017
spermatid differentiation GO:0048515 4 0.017
positive regulation of organelle organization GO:0010638 195 0.017
cell fate commitment involved in pattern specification GO:0060581 1 0.017
blood vessel endothelial cell migration GO:0043534 42 0.017

SMO disease predictions

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 41 0.134
holoprosencephaly DOID:4621 6 0.134
congenital nervous system abnormality DOID:2490 21 0.134
musculoskeletal system disease DOID:17 223 0.052
bone disease DOID:0080001 88 0.027
connective tissue disease DOID:65 109 0.027
cancer DOID:162 167 0.025
disease of cellular proliferation DOID:14566 174 0.025
sensory system disease DOID:0050155 203 0.023
nervous system disease DOID:863 431 0.023
disease of metabolism DOID:0014667 295 0.022
bone development disease DOID:0080006 55 0.022
organ system cancer DOID:0050686 164 0.021
eye and adnexa disease DOID:1492 150 0.019
inherited metabolic disorder DOID:655 242 0.019