Homo sapiens

14 known processes

MAGED1

melanoma antigen family D, 1

(Aliases: DLXIN-1,NRAGE)

MAGED1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein ubiquitination GO:0016567 314 0.456
cellular protein catabolic process GO:0044257 261 0.443
protein modification by small protein conjugation GO:0032446 342 0.386
negative regulation of cell proliferation GO:0008285 228 0.292
negative regulation of epithelial cell proliferation GO:0050680 48 0.266
protein catabolic process GO:0030163 325 0.257
negative regulation of protein metabolic process GO:0051248 391 0.095
cellular macromolecule catabolic process GO:0044265 380 0.087
regulation of epithelial cell proliferation GO:0050678 113 0.077
modification dependent protein catabolic process GO:0019941 209 0.074
apoptotic signaling pathway GO:0097190 268 0.069
Mouse
regulation of transferase activity GO:0051338 355 0.068
Mouse
ubiquitin dependent protein catabolic process GO:0006511 206 0.068
regulation of cellular amino acid metabolic process GO:0006521 6 0.067
cellular response to endogenous stimulus GO:0071495 336 0.061
nervous system development GO:0007399 293 0.057
negative regulation of cellular protein metabolic process GO:0032269 353 0.056
regulation of cellular amine metabolic process GO:0033238 11 0.055
positive regulation of cellular amine metabolic process GO:0033240 7 0.054
negative regulation of programmed cell death GO:0043069 321 0.053
cellular amino acid metabolic process GO:0006520 116 0.049
protein kinase a signaling GO:0010737 9 0.048
cellular amine metabolic process GO:0044106 41 0.046
determination of adult lifespan GO:0008340 2 0.046
vesicle mediated transport GO:0016192 371 0.045
aortic valve development GO:0003176 3 0.045
response to growth factor GO:0070848 205 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.044
negative regulation of protein modification process GO:0031400 200 0.043
positive regulation of cell fate specification GO:0042660 2 0.043
regulation of establishment of protein localization GO:0070201 242 0.043
negative regulation of apoptotic process GO:0043066 316 0.042
myeloid cell differentiation GO:0030099 117 0.042
protein acetylation GO:0006473 116 0.042
locomotory behavior GO:0007626 1 0.040
proteasomal protein catabolic process GO:0010498 176 0.039
cellular response to dna damage stimulus GO:0006974 379 0.038
single organism cellular localization GO:1902580 332 0.037
cardiac ventricle formation GO:0003211 2 0.036
limbic system development GO:0021761 3 0.036
cell cycle arrest GO:0007050 71 0.035
enzyme linked receptor protein signaling pathway GO:0007167 303 0.035
cardiac right ventricle formation GO:0003219 1 0.035
cardiac right ventricle morphogenesis GO:0003215 3 0.035
purine ribonucleotide catabolic process GO:0009154 404 0.034
positive regulation of programmed cell death GO:0043068 249 0.034
Mouse
aging GO:0007568 66 0.034
multicellular organismal aging GO:0010259 3 0.033
regulation of proteolysis GO:0030162 293 0.033
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.033
forebrain generation of neurons GO:0021872 3 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
mitotic cell cycle process GO:1903047 286 0.032
regulation of meiotic cell cycle GO:0051445 4 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
response to abiotic stimulus GO:0009628 336 0.031
glial cell migration GO:0008347 4 0.031
photoreceptor cell differentiation GO:0046530 2 0.030
organonitrogen compound biosynthetic process GO:1901566 200 0.030
positive regulation of proteolysis GO:0045862 142 0.029
i kappab kinase nf kappab signaling GO:0007249 166 0.029
modification dependent macromolecule catabolic process GO:0043632 212 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.027
positive regulation of hydrolase activity GO:0051345 331 0.027
neuron development GO:0048666 113 0.027
neuromuscular junction development GO:0007528 3 0.027
cell adhesion GO:0007155 325 0.027
morphogenesis of embryonic epithelium GO:0016331 4 0.026
wnt signaling pathway GO:0016055 156 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
regulation of cell cycle process GO:0010564 266 0.026
negative regulation of cell death GO:0060548 345 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.026
cell division GO:0051301 168 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.025
neurological system process GO:0050877 163 0.025
protein processing GO:0016485 226 0.024
mrna splicing via spliceosome GO:0000398 89 0.024
spinal cord development GO:0021510 4 0.024
nerve development GO:0021675 4 0.024
post embryonic development GO:0009791 2 0.024
cellular ketone metabolic process GO:0042180 80 0.024
compound eye development GO:0048749 1 0.023
amine metabolic process GO:0009308 44 0.023
cellular response to glucocorticoid stimulus GO:0071385 4 0.023
epidermis morphogenesis GO:0048730 3 0.023
hindbrain development GO:0030902 3 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
single organism membrane organization GO:0044802 268 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.022
protein secretion GO:0009306 98 0.022
regulation of peptidase activity GO:0052547 180 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
cellular response to uv GO:0034644 32 0.022
regulation of protein catabolic process GO:0042176 155 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.022
positive regulation of cell cycle process GO:0090068 106 0.022
mrna metabolic process GO:0016071 175 0.022
regeneration GO:0031099 4 0.022
response to cytokine GO:0034097 232 0.022
regulation of cardiac muscle cell proliferation GO:0060043 4 0.022
ribonucleoside catabolic process GO:0042454 406 0.021
positive regulation of apoptotic signaling pathway GO:2001235 70 0.021
Mouse
astrocyte differentiation GO:0048708 4 0.021
oxidation reduction process GO:0055114 396 0.021
endoplasmic reticulum organization GO:0007029 20 0.020
adult locomotory behavior GO:0008344 1 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
signal transduction by p53 class mediator GO:0072331 72 0.020
sensory perception of pain GO:0019233 4 0.020
system process GO:0003008 349 0.020
ras protein signal transduction GO:0007265 73 0.019
brain development GO:0007420 97 0.019
extrinsic apoptotic signaling pathway GO:0097191 119 0.019
regulation of protein processing GO:0070613 150 0.019
neural tube formation GO:0001841 3 0.019
protein sumoylation GO:0016925 25 0.019
stem cell division GO:0017145 2 0.019
regulation of growth GO:0040008 165 0.019
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
regulation of cellular component movement GO:0051270 334 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
transmembrane transport GO:0055085 399 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
positive regulation of peptidase activity GO:0010952 88 0.018
zymogen activation GO:0031638 70 0.018
establishment of tissue polarity GO:0007164 3 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
protein homooligomerization GO:0051260 100 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
golgi vesicle transport GO:0048193 80 0.018
somatic stem cell division GO:0048103 1 0.018
midbrain development GO:0030901 45 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
peripheral nervous system development GO:0007422 2 0.018
protein localization to membrane GO:0072657 160 0.018
cardiac chamber formation GO:0003207 2 0.018
forebrain neuron differentiation GO:0021879 3 0.017
cytoplasmic transport GO:0016482 379 0.017
membrane organization GO:0061024 292 0.017
behavior GO:0007610 112 0.017
neurogenesis GO:0022008 169 0.017
central nervous system development GO:0007417 123 0.017
regulation of ubiquitin protein transferase activity GO:0051438 28 0.017
cellular response to oxidative stress GO:0034599 85 0.017
regulation of cellular response to stress GO:0080135 244 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
response to biotic stimulus GO:0009607 276 0.017
motor neuron axon guidance GO:0008045 2 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
organelle fission GO:0048285 149 0.017
regulation of cellular response to growth factor stimulus GO:0090287 76 0.017
lipid metabolic process GO:0006629 381 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
Mouse
regulation of cell division GO:0051302 116 0.016
cellular chemical homeostasis GO:0055082 180 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
head development GO:0060322 108 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
Mouse
cellular modified amino acid metabolic process GO:0006575 64 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
regulation of secretion by cell GO:1903530 177 0.016
embryonic hindlimb morphogenesis GO:0035116 2 0.016
aortic valve morphogenesis GO:0003180 3 0.016
regulation of secretion GO:0051046 194 0.016
regulation of cell development GO:0060284 161 0.016
memory GO:0007613 3 0.016
regulation of response to dna damage stimulus GO:2001020 94 0.016
ventricular septum morphogenesis GO:0060412 3 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
response to axon injury GO:0048678 1 0.016
regulation of locomotion GO:0040012 329 0.016
immune system development GO:0002520 195 0.016
regulation of cell cycle arrest GO:0071156 36 0.016
sensory perception GO:0007600 103 0.016
establishment of planar polarity GO:0001736 3 0.016
rna processing GO:0006396 255 0.016
cell development GO:0048468 328 0.015
secretion by cell GO:0032940 226 0.015
pharynx development GO:0060465 1 0.015
mating GO:0007618 1 0.015
epithelium development GO:0060429 227 0.015
Mouse
regulation of cell differentiation GO:0045595 393 0.015
response to radiation GO:0009314 151 0.015
hippocampus development GO:0021766 1 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
mrna processing GO:0006397 133 0.015
organophosphate catabolic process GO:0046434 430 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
hair follicle morphogenesis GO:0031069 2 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
muscle cell fate commitment GO:0042693 4 0.015
endomembrane system organization GO:0010256 196 0.015
positive regulation of cell cycle GO:0045787 140 0.015
cellular response to external stimulus GO:0071496 111 0.015
regulation of protein kinase activity GO:0045859 289 0.015
Mouse
cellular homeostasis GO:0019725 196 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
atp metabolic process GO:0046034 176 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
leukocyte differentiation GO:0002521 98 0.014
regulation of cardioblast differentiation GO:0051890 4 0.014
purine containing compound biosynthetic process GO:0072522 88 0.014
response to light stimulus GO:0009416 87 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
positive regulation of protein ubiquitination GO:0031398 53 0.014
dephosphorylation GO:0016311 209 0.014
positive regulation of transport GO:0051050 336 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
mitotic cell cycle GO:0000278 326 0.014
response to oxygen containing compound GO:1901700 369 0.014
response to transforming growth factor beta GO:0071559 94 0.014
regulation of protein transport GO:0051223 213 0.014
regulation of protein localization GO:0032880 296 0.014
regulation of neuron death GO:1901214 56 0.014
gtp catabolic process GO:0006184 237 0.014
neuron differentiation GO:0030182 138 0.014
positive regulation of myeloid cell differentiation GO:0045639 39 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
cellular senescence GO:0090398 34 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.014
protein complex disassembly GO:0043241 52 0.014
inner ear morphogenesis GO:0042472 4 0.013
purine containing compound catabolic process GO:0072523 411 0.013
cellular response to lipid GO:0071396 127 0.013
dna damage checkpoint GO:0000077 68 0.013
wound healing GO:0042060 115 0.013
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
neuron projection development GO:0031175 106 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
meiosis i GO:0007127 4 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
positive regulation of neural precursor cell proliferation GO:2000179 2 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
ribose phosphate biosynthetic process GO:0046390 82 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
Mouse
defense response GO:0006952 315 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
negative regulation of transferase activity GO:0051348 124 0.013
positive regulation of cell migration GO:0030335 172 0.013
cell growth GO:0016049 160 0.013
positive regulation of gliogenesis GO:0014015 4 0.013
cellular lipid metabolic process GO:0044255 303 0.013
eye photoreceptor cell differentiation GO:0001754 2 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
dna repair GO:0006281 198 0.013
salivary gland morphogenesis GO:0007435 4 0.013
activation of cysteine type endopeptidase activity GO:0097202 57 0.013
spermatid development GO:0007286 4 0.013
visual behavior GO:0007632 2 0.013
pericardium development GO:0060039 2 0.013
neuroblast proliferation GO:0007405 4 0.013
cellular component morphogenesis GO:0032989 314 0.013
biological adhesion GO:0022610 331 0.013
trail activated apoptotic signaling pathway GO:0036462 4 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
apoptotic mitochondrial changes GO:0008637 57 0.013
cofactor metabolic process GO:0051186 87 0.013
female gamete generation GO:0007292 2 0.012
actin filament based movement GO:0030048 17 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
tissue regeneration GO:0042246 3 0.012
neuron projection regeneration GO:0031102 1 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
positive regulation of cytokine production GO:0001819 167 0.012
regulation of kinase activity GO:0043549 314 0.012
Mouse
negative regulation of gliogenesis GO:0014014 3 0.012
tube closure GO:0060606 3 0.012
positive regulation of transferase activity GO:0051347 227 0.012
Mouse
negative regulation of cellular catabolic process GO:0031330 83 0.012
regulation of response to external stimulus GO:0032101 222 0.012
heart formation GO:0060914 2 0.012
optic nerve development GO:0021554 2 0.012
anion transport GO:0006820 161 0.012
ion homeostasis GO:0050801 230 0.012
negative regulation of proteolysis GO:0045861 132 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.012
regulation of glial cell differentiation GO:0045685 3 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.012
cell projection morphogenesis GO:0048858 129 0.012
negative regulation of protein processing GO:0010955 142 0.012
forebrain neuron development GO:0021884 2 0.012
associative learning GO:0008306 1 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.012
substantia nigra development GO:0021762 45 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
Mouse
cerebellum development GO:0021549 2 0.012
mitochondrion organization GO:0007005 156 0.012
ossification GO:0001503 121 0.012
negative regulation of protein maturation GO:1903318 142 0.012
regulation of organ formation GO:0003156 4 0.012
positive regulation of locomotion GO:0040017 186 0.012
metencephalon development GO:0022037 2 0.012
response to hormone GO:0009725 175 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
negative regulation of glial cell differentiation GO:0045686 1 0.012
regulation of protein secretion GO:0050708 86 0.012
negative regulation of hydrolase activity GO:0051346 182 0.011
demethylation GO:0070988 37 0.011
regulation of endothelial cell differentiation GO:0045601 4 0.011
positive regulation of neuroblast proliferation GO:0002052 2 0.011
negative regulation of cell cycle GO:0045786 193 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.011
anatomical structure homeostasis GO:0060249 100 0.011
rho protein signal transduction GO:0007266 26 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
carboxylic acid catabolic process GO:0046395 71 0.011
regulation of mitochondrion organization GO:0010821 54 0.011
primary neural tube formation GO:0014020 3 0.011
regulation of glial cell proliferation GO:0060251 4 0.011
mesodermal cell fate specification GO:0007501 2 0.011
negative regulation of glial cell proliferation GO:0060253 2 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
venous blood vessel development GO:0060841 2 0.011
cation transport GO:0006812 331 0.011
positive regulation of developmental process GO:0051094 314 0.011
Mouse
skin development GO:0043588 76 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
regulation of cardiac muscle tissue growth GO:0055021 4 0.011
regulation of cell cycle GO:0051726 393 0.011
atrioventricular valve development GO:0003171 3 0.011
cell projection organization GO:0030030 252 0.011
rna interference GO:0016246 4 0.011
negative regulation of developmental process GO:0051093 247 0.011
ameboidal type cell migration GO:0001667 135 0.011
cellular response to toxic substance GO:0097237 4 0.011
negative regulation of kinase activity GO:0033673 106 0.011
cell morphogenesis GO:0000902 296 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
cochlea development GO:0090102 1 0.011
endocytosis GO:0006897 159 0.011
positive regulation of cell cycle arrest GO:0071158 23 0.011
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.011
positive regulation of cell motility GO:2000147 177 0.011
coenzyme metabolic process GO:0006732 65 0.011
g protein coupled receptor catabolic process GO:1990172 1 0.011
actin mediated cell contraction GO:0070252 12 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
sex determination GO:0007530 3 0.011
regulation of transmembrane transporter activity GO:0022898 74 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
lens development in camera type eye GO:0002088 2 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.010
tissue homeostasis GO:0001894 63 0.010
purine nucleotide catabolic process GO:0006195 405 0.010
positive regulation of mapk cascade GO:0043410 190 0.010
Mouse
regulation of cell migration GO:0030334 289 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.010
positive regulation of gtp catabolic process GO:0033126 166 0.010
response to inorganic substance GO:0010035 127 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.010
mitotic cell cycle checkpoint GO:0007093 68 0.010
oogenesis GO:0048477 2 0.010
response to other organism GO:0051707 261 0.010
oocyte development GO:0048599 1 0.010
prostate gland morphogenesis GO:0060512 1 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
secretion GO:0046903 254 0.010
hemopoiesis GO:0030097 180 0.010
receptor metabolic process GO:0043112 81 0.010
rhythmic behavior GO:0007622 2 0.010
regulation of neuroblast proliferation GO:1902692 3 0.010
myeloid leukocyte differentiation GO:0002573 60 0.010
myosin filament assembly GO:0031034 2 0.010
lymphocyte homeostasis GO:0002260 4 0.010
sequestering of calcium ion GO:0051208 17 0.010
response to mechanical stimulus GO:0009612 51 0.010
establishment of protein localization to plasma membrane GO:0090002 68 0.010
g1 s transition of mitotic cell cycle GO:0000082 78 0.010
regulation of ligase activity GO:0051340 29 0.010

MAGED1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.177
nervous system disease DOID:863 431 0.177
neurodegenerative disease DOID:1289 102 0.174
primary ciliary dyskinesia DOID:9562 27 0.053
musculoskeletal system disease DOID:17 223 0.027
spinocerebellar degeneration DOID:2478 27 0.021
connective tissue disease DOID:65 109 0.020
cardiovascular system disease DOID:1287 106 0.019
disease of metabolism DOID:0014667 295 0.018
retinal disease DOID:5679 118 0.018
sensory system disease DOID:0050155 203 0.018
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
bone disease DOID:0080001 88 0.018
immune system disease DOID:2914 155 0.016
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
neuropathy DOID:870 52 0.012
brain disease DOID:936 73 0.011
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011
retinal degeneration DOID:8466 89 0.011
retinitis pigmentosa DOID:10584 51 0.011
spinocerebellar ataxia DOID:1441 26 0.010
heart disease DOID:114 68 0.010