Homo sapiens

145 known processes

PEX2

peroxisomal biogenesis factor 2

(Aliases: RNF72,PMP3,PAF1,PMP35,PXMP3,ZWS3)

PEX2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein targeting to peroxisome GO:0006625 15 0.461
peroxisome organization GO:0007031 28 0.287
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.268
ribonucleoside monophosphate metabolic process GO:0009161 187 0.216
positive regulation of catabolic process GO:0009896 310 0.215
single organism membrane fusion GO:0044801 37 0.160
protein import into peroxisome matrix GO:0016558 11 0.158
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.138
purine nucleoside triphosphate metabolic process GO:0009144 412 0.130
membrane organization GO:0061024 292 0.120
lipid metabolic process GO:0006629 381 0.119
ribonucleoside triphosphate catabolic process GO:0009203 391 0.109
oxidation reduction process GO:0055114 396 0.106
cytoplasmic transport GO:0016482 379 0.102
post embryonic development GO:0009791 2 0.099
vesicle mediated transport GO:0016192 371 0.091
purine ribonucleoside metabolic process GO:0046128 437 0.091
single organism cellular localization GO:1902580 332 0.091
cellular macromolecular complex assembly GO:0034622 324 0.090
positive regulation of cellular catabolic process GO:0031331 284 0.088
single organism membrane organization GO:0044802 268 0.083
membrane fusion GO:0061025 43 0.081
ribonucleoside catabolic process GO:0042454 406 0.080
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.069
purine nucleoside monophosphate metabolic process GO:0009126 186 0.066
organophosphate catabolic process GO:0046434 430 0.063
nucleoside monophosphate metabolic process GO:0009123 191 0.060
ribonucleoside triphosphate metabolic process GO:0009199 412 0.057
transmembrane transport GO:0055085 399 0.055
intracellular protein transmembrane import GO:0044743 23 0.055
alcohol metabolic process GO:0006066 114 0.054
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.052
atp metabolic process GO:0046034 176 0.050
nucleoside catabolic process GO:0009164 408 0.050
endosomal transport GO:0016197 129 0.046
purine containing compound catabolic process GO:0072523 411 0.046
nucleoside triphosphate metabolic process GO:0009141 422 0.046
establishment of protein localization to organelle GO:0072594 172 0.045
positive regulation of hydrolase activity GO:0051345 331 0.044
purine ribonucleoside catabolic process GO:0046130 398 0.043
glycosyl compound catabolic process GO:1901658 413 0.043
establishment of protein localization to peroxisome GO:0072663 15 0.042
organic anion transport GO:0015711 103 0.041
protein targeting GO:0006605 187 0.041
anion transport GO:0006820 161 0.040
protein localization to membrane GO:0072657 160 0.040
protein localization to organelle GO:0033365 280 0.040
nucleoside phosphate catabolic process GO:1901292 412 0.040
purine nucleotide catabolic process GO:0006195 405 0.039
purine ribonucleotide catabolic process GO:0009154 404 0.038
nervous system development GO:0007399 293 0.038
Mouse
long chain fatty acid catabolic process GO:0042758 3 0.036
monocarboxylic acid metabolic process GO:0032787 185 0.036
cellular lipid metabolic process GO:0044255 303 0.036
guanosine containing compound metabolic process GO:1901068 244 0.035
protein import GO:0017038 130 0.035
organophosphate biosynthetic process GO:0090407 163 0.034
negative regulation of phosphate metabolic process GO:0045936 267 0.034
cellular ketone metabolic process GO:0042180 80 0.034
positive regulation of transport GO:0051050 336 0.033
negative regulation of protein metabolic process GO:0051248 391 0.032
protein import into peroxisome membrane GO:0045046 5 0.032
ribonucleotide catabolic process GO:0009261 405 0.032
nucleoside triphosphate catabolic process GO:0009143 394 0.031
purine nucleoside catabolic process GO:0006152 398 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
lipid biosynthetic process GO:0008610 177 0.029
Mouse
positive regulation of nucleotide catabolic process GO:0030813 185 0.028
ion transmembrane transport GO:0034220 338 0.028
segmentation GO:0035282 4 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.027
intracellular protein transport GO:0006886 270 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.026
response to other organism GO:0051707 261 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
small molecule catabolic process GO:0044282 92 0.025
protein modification by small protein conjugation GO:0032446 342 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
regulation of lipid metabolic process GO:0019216 96 0.024
Mouse
regulation of nucleotide metabolic process GO:0006140 269 0.023
endocytosis GO:0006897 159 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
regulation of transferase activity GO:0051338 355 0.022
spermatid development GO:0007286 4 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
nitrogen compound transport GO:0071705 191 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
vesicle organization GO:0016050 62 0.021
nucleotide catabolic process GO:0009166 408 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
response to external biotic stimulus GO:0043207 261 0.021
positive regulation of phosphorylation GO:0042327 394 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
protein localization to peroxisome GO:0072662 15 0.020
small molecule biosynthetic process GO:0044283 157 0.020
Mouse
regulation of protein localization GO:0032880 296 0.020
phagosome acidification GO:0090383 4 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
atp catabolic process GO:0006200 157 0.019
cellular amine metabolic process GO:0044106 41 0.019
diterpenoid metabolic process GO:0016101 20 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
cellular amino acid metabolic process GO:0006520 116 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.018
generation of neurons GO:0048699 152 0.018
Mouse
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
intracellular protein transmembrane transport GO:0065002 24 0.017
engulfment of apoptotic cell GO:0043652 2 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
neurogenesis GO:0022008 169 0.017
Mouse
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
lipid oxidation GO:0034440 33 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.016
alcohol biosynthetic process GO:0046165 52 0.016
Mouse
exocytosis GO:0006887 71 0.016
cellular component morphogenesis GO:0032989 314 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
spermatid differentiation GO:0048515 4 0.016
positive regulation of cellular component organization GO:0051130 376 0.015
regulation of proteolysis GO:0030162 293 0.015
fatty acid metabolic process GO:0006631 115 0.015
amine metabolic process GO:0009308 44 0.015
protein oligomerization GO:0051259 173 0.015
cell projection organization GO:0030030 252 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
cellular lipid catabolic process GO:0044242 65 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
protein catabolic process GO:0030163 325 0.015
i kappab kinase nf kappab signaling GO:0007249 166 0.015
locomotory behavior GO:0007626 1 0.015
neuromuscular junction development GO:0007528 3 0.015
lipid localization GO:0010876 106 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
rna processing GO:0006396 255 0.014
negative regulation of transport GO:0051051 176 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
gtp metabolic process GO:0046039 239 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
lipid catabolic process GO:0016042 84 0.014
regulation of protein kinase activity GO:0045859 289 0.013
lytic vacuole organization GO:0080171 24 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
innate immune response GO:0045087 178 0.013
microtubule based process GO:0007017 210 0.013
rab protein signal transduction GO:0032482 4 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
protein homooligomerization GO:0051260 100 0.013
ras protein signal transduction GO:0007265 73 0.013
plasma membrane organization GO:0007009 115 0.013
glycerolipid biosynthetic process GO:0045017 51 0.013
maintenance of location GO:0051235 112 0.013
organelle fusion GO:0048284 36 0.013
adult locomotory behavior GO:0008344 1 0.013
signal transduction by phosphorylation GO:0023014 297 0.012
memory GO:0007613 3 0.012
positive regulation of atpase activity GO:0032781 19 0.012
purine ribonucleotide biosynthetic process GO:0009152 79 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
regulation of steroid metabolic process GO:0019218 32 0.012
Mouse
negative regulation of organelle organization GO:0010639 126 0.012
gtp catabolic process GO:0006184 237 0.012
dna repair GO:0006281 198 0.012
vesicle fusion GO:0006906 17 0.012
anterior posterior axis specification GO:0009948 2 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
reproduction GO:0000003 63 0.012
immune response GO:0006955 307 0.012
negative regulation of cell death GO:0060548 345 0.012
purine containing compound biosynthetic process GO:0072522 88 0.012
system process GO:0003008 349 0.012
protein transmembrane transport GO:0071806 25 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.011
positive regulation of cell cycle GO:0045787 140 0.011
lysosome organization GO:0007040 24 0.011
mapk cascade GO:0000165 288 0.011
protein localization to plasma membrane GO:0072659 93 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
regulation of secretion GO:0051046 194 0.011
rna splicing GO:0008380 131 0.011
chromatin modification GO:0016568 298 0.011
endomembrane system organization GO:0010256 196 0.011
regulation of atpase activity GO:0043462 25 0.011
cell morphogenesis GO:0000902 296 0.011
small gtpase mediated signal transduction GO:0007264 78 0.010
regulation of mapk cascade GO:0043408 262 0.010
secretion GO:0046903 254 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
carbohydrate metabolic process GO:0005975 207 0.010
chemical homeostasis GO:0048878 306 0.010
Mouse
nucleus localization GO:0051647 1 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.010
regulation of cellular component biogenesis GO:0044087 281 0.010
steroid metabolic process GO:0008202 94 0.010
Mouse
protein ubiquitination GO:0016567 314 0.010
regulation of gtp catabolic process GO:0033124 180 0.010
ethanol metabolic process GO:0006067 5 0.010
rna interference GO:0016246 4 0.010
eosinophil degranulation GO:0043308 2 0.010

PEX2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.122
inherited metabolic disorder DOID:655 242 0.034
amino acid metabolic disorder DOID:9252 50 0.016
disease of cellular proliferation DOID:14566 174 0.012
cancer DOID:162 167 0.012
central nervous system disease DOID:331 186 0.011
nervous system disease DOID:863 431 0.011
organ system cancer DOID:0050686 164 0.010