Homo sapiens

87 known processes

PEX5

peroxisomal biogenesis factor 5

(Aliases: FLJ51948,FLJ50634,PXR1,PTS1R,PTS1-BP,FLJ50721)

PEX5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peroxisomal transport GO:0043574 15 1.000
protein localization to peroxisome GO:0072662 15 1.000
establishment of protein localization to peroxisome GO:0072663 15 0.999
protein import into peroxisome matrix GO:0016558 11 0.998
intracellular protein transmembrane transport GO:0065002 24 0.998
peroxisome organization GO:0007031 28 0.993
protein targeting to peroxisome GO:0006625 15 0.991
protein import into peroxisome matrix docking GO:0016560 2 0.986
protein transmembrane transport GO:0071806 25 0.903
oxidation reduction process GO:0055114 396 0.882
Mouse
organic acid catabolic process GO:0016054 71 0.870
Mouse
monocarboxylic acid metabolic process GO:0032787 185 0.848
Mouse
cytoplasmic transport GO:0016482 379 0.684
small molecule catabolic process GO:0044282 92 0.676
Mouse
transmembrane transport GO:0055085 399 0.667
establishment of protein localization to organelle GO:0072594 172 0.565
spermatid development GO:0007286 4 0.559
lipid metabolic process GO:0006629 381 0.512
Mouse
protein modification by small protein conjugation GO:0032446 342 0.501
protein ubiquitination GO:0016567 314 0.461
intracellular protein transport GO:0006886 270 0.436
protein import GO:0017038 130 0.421
protein targeting GO:0006605 187 0.384
lipid modification GO:0030258 84 0.366
Mouse
cellular lipid metabolic process GO:0044255 303 0.357
Mouse
protein localization to organelle GO:0033365 280 0.355
protein monoubiquitination GO:0006513 39 0.345
intracellular protein transmembrane import GO:0044743 23 0.341
alcohol metabolic process GO:0006066 114 0.307
protein to membrane docking GO:0022615 3 0.297
cellular lipid catabolic process GO:0044242 65 0.225
Mouse
protein tetramerization GO:0051262 47 0.196
cell division GO:0051301 168 0.180
protein homotetramerization GO:0051289 28 0.179
spermatid differentiation GO:0048515 4 0.168
maintenance of location in cell GO:0051651 62 0.162
cell development GO:0048468 328 0.162
Mouse
single organism cellular localization GO:1902580 332 0.151
lipid oxidation GO:0034440 33 0.150
Mouse
fatty acid catabolic process GO:0009062 29 0.116
Mouse
cellular amino acid metabolic process GO:0006520 116 0.098
negative regulation of cellular component organization GO:0051129 235 0.094
cellular amine metabolic process GO:0044106 41 0.094
maintenance of location GO:0051235 112 0.088
regulation of protein complex assembly GO:0043254 147 0.087
maintenance of protein location GO:0045185 57 0.086
regulation of cellular component biogenesis GO:0044087 281 0.084
amine metabolic process GO:0009308 44 0.082
negative regulation of protein complex assembly GO:0031333 43 0.080
regulation of cellular amino acid metabolic process GO:0006521 6 0.079
post embryonic development GO:0009791 2 0.076
regulation of cellular ketone metabolic process GO:0010565 50 0.074
lipid biosynthetic process GO:0008610 177 0.071
locomotory behavior GO:0007626 1 0.069
myeloid dendritic cell differentiation GO:0043011 3 0.068
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.065
diterpenoid metabolic process GO:0016101 20 0.063
regulation of cellular amine metabolic process GO:0033238 11 0.062
cellular component disassembly GO:0022411 92 0.053
multicellular organismal aging GO:0010259 3 0.050
myeloid cell differentiation GO:0030099 117 0.044
macromolecular complex disassembly GO:0032984 60 0.044
maintenance of protein location in cell GO:0032507 56 0.043
positive regulation of phosphorylation GO:0042327 394 0.042
cellular protein complex disassembly GO:0043624 36 0.042
steroid metabolic process GO:0008202 94 0.042
myeloid leukocyte differentiation GO:0002573 60 0.041
cellular ketone metabolic process GO:0042180 80 0.040
protein import into peroxisome membrane GO:0045046 5 0.039
hemopoiesis GO:0030097 180 0.039
microtubule based movement GO:0007018 32 0.038
fatty acid metabolic process GO:0006631 115 0.037
Mouse
coenzyme metabolic process GO:0006732 65 0.037
determination of adult lifespan GO:0008340 2 0.037
chromatin organization GO:0006325 351 0.036
protein oligomerization GO:0051259 173 0.036
negative regulation of protein binding GO:0032091 35 0.036
regulation of binding GO:0051098 111 0.034
membrane organization GO:0061024 292 0.033
organelle fission GO:0048285 149 0.033
negative regulation of cellular amine metabolic process GO:0033239 3 0.033
negative regulation of apoptotic process GO:0043066 316 0.032
positive regulation of cellular amine metabolic process GO:0033240 7 0.032
terpenoid metabolic process GO:0006721 27 0.031
single organism reproductive process GO:0044702 98 0.030
neuroblast proliferation GO:0007405 4 0.030
organophosphate catabolic process GO:0046434 430 0.030
blastoderm segmentation GO:0007350 2 0.030
organic hydroxy compound metabolic process GO:1901615 147 0.029
cytoskeleton dependent intracellular transport GO:0030705 21 0.029
microtubule based process GO:0007017 210 0.029
retinoid metabolic process GO:0001523 18 0.028
reproductive process GO:0022414 106 0.028
forebrain generation of neurons GO:0021872 3 0.027
peroxisome fission GO:0016559 10 0.027
immune system development GO:0002520 195 0.027
developmental process involved in reproduction GO:0003006 66 0.027
myeloid dendritic cell activation GO:0001773 4 0.026
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
leukocyte differentiation GO:0002521 98 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.026
regulation of reactive oxygen species metabolic process GO:2000377 41 0.026
positive regulation of protein phosphorylation GO:0001934 313 0.026
actin filament based process GO:0030029 224 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
anterior posterior axis specification embryo GO:0008595 2 0.025
protein catabolic process GO:0030163 325 0.025
positive regulation of catabolic process GO:0009896 310 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.024
memory GO:0007613 3 0.024
purine containing compound catabolic process GO:0072523 411 0.024
sulfur compound metabolic process GO:0006790 101 0.024
hematopoietic or lymphoid organ development GO:0048534 186 0.023
segmentation GO:0035282 4 0.023
regulation of dna metabolic process GO:0051052 153 0.023
regulation of kinase activity GO:0043549 314 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
mitotic cell cycle process GO:1903047 286 0.022
positive regulation of immune system process GO:0002684 283 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
negative regulation of protein oligomerization GO:0032460 8 0.022
regulation of cell differentiation GO:0045595 393 0.022
negative regulation of cell death GO:0060548 345 0.022
response to oxidative stress GO:0006979 121 0.022
signal transduction by phosphorylation GO:0023014 297 0.022
biological adhesion GO:0022610 331 0.022
purine nucleotide catabolic process GO:0006195 405 0.021
regulation of cell cycle GO:0051726 393 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
peptidyl lysine acetylation GO:0018394 101 0.021
cellular response to oxidative stress GO:0034599 85 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
mapk cascade GO:0000165 288 0.020
regulation of cell cycle process GO:0010564 266 0.020
mitotic cell cycle GO:0000278 326 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
generation of precursor metabolites and energy GO:0006091 68 0.020
morphogenesis of embryonic epithelium GO:0016331 4 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
regulation of transferase activity GO:0051338 355 0.019
neuromuscular junction development GO:0007528 3 0.019
positive regulation of cell death GO:0010942 263 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
microtubule anchoring GO:0034453 24 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
nucleotide catabolic process GO:0009166 408 0.019
nerve development GO:0021675 4 0.019
regulation of mapk cascade GO:0043408 262 0.019
cellular homeostasis GO:0019725 196 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
negative regulation of multicellular organismal process GO:0051241 317 0.018
regeneration GO:0031099 4 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
protein localization to nucleus GO:0034504 136 0.018
regulation of protein localization GO:0032880 296 0.018
response to abiotic stimulus GO:0009628 336 0.018
negative regulation of chromatin silencing GO:0031936 4 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
positive regulation of transferase activity GO:0051347 227 0.017
glycerolipid metabolic process GO:0046486 107 0.017
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.017
spermatogenesis GO:0007283 22 0.017
negative regulation of protein modification process GO:0031400 200 0.017
regulation of protein binding GO:0043393 66 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
protein acetylation GO:0006473 116 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
growth GO:0040007 202 0.017
Mouse
gtp catabolic process GO:0006184 237 0.017
carbohydrate metabolic process GO:0005975 207 0.017
leukocyte activation GO:0045321 164 0.016
response to external biotic stimulus GO:0043207 261 0.016
regulation of protein catabolic process GO:0042176 155 0.016
system process GO:0003008 349 0.016
Mouse
response to cytokine GO:0034097 232 0.016
regulation of neuroblast proliferation GO:1902692 3 0.016
endosomal transport GO:0016197 129 0.016
negative regulation of developmental process GO:0051093 247 0.016
oocyte differentiation GO:0009994 2 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
female gamete generation GO:0007292 2 0.016
salivary gland morphogenesis GO:0007435 4 0.016
lipid catabolic process GO:0016042 84 0.016
Mouse
histone modification GO:0016570 251 0.016
positive regulation of kinase activity GO:0033674 204 0.016
ras protein signal transduction GO:0007265 73 0.016
multicellular organism reproduction GO:0032504 42 0.015
regulation of proteolysis GO:0030162 293 0.015
oocyte development GO:0048599 1 0.015
mitochondrion organization GO:0007005 156 0.015
Mouse
anterior posterior axis specification GO:0009948 2 0.015
tripartite regional subdivision GO:0007351 2 0.015
protein localization to membrane GO:0072657 160 0.015
cell growth GO:0016049 160 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
carboxylic acid catabolic process GO:0046395 71 0.015
Mouse
purine nucleoside catabolic process GO:0006152 398 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
cerebral cortex cell migration GO:0021795 3 0.015
Mouse
cell morphogenesis GO:0000902 296 0.015
alcohol catabolic process GO:0046164 20 0.015
multi organism reproductive process GO:0044703 54 0.015
single organism nuclear import GO:1902593 104 0.015
chromatin modification GO:0016568 298 0.015
chaperone mediated protein transport GO:0072321 5 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
hindbrain development GO:0030902 3 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
covalent chromatin modification GO:0016569 254 0.015
thymus development GO:0048538 3 0.015
dicarboxylic acid metabolic process GO:0043648 29 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
associative learning GO:0008306 1 0.015
regulation of locomotion GO:0040012 329 0.014
dephosphorylation GO:0016311 209 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
cell activation GO:0001775 213 0.014
innate immune response GO:0045087 178 0.014
nervous system development GO:0007399 293 0.014
Mouse
nuclear transport GO:0051169 179 0.014
metencephalon development GO:0022037 2 0.014
cell projection organization GO:0030030 252 0.014
regulation of protein kinase activity GO:0045859 289 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
multicellular organismal reproductive process GO:0048609 40 0.014
very long chain fatty acid catabolic process GO:0042760 3 0.014
oogenesis GO:0048477 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
regulation of defense response GO:0031347 154 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
regulation of cell motility GO:2000145 299 0.014
membrane biogenesis GO:0044091 13 0.014
peripheral nervous system development GO:0007422 2 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
forebrain neuron differentiation GO:0021879 3 0.013
cofactor metabolic process GO:0051186 87 0.013
energy derivation by oxidation of organic compounds GO:0015980 43 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
protein maturation GO:0051604 233 0.013
polyol metabolic process GO:0019751 32 0.013
neuron differentiation GO:0030182 138 0.013
Mouse
positive regulation of protein kinase activity GO:0045860 190 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
regulation of cell adhesion GO:0030155 166 0.013
regulation of cell development GO:0060284 161 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
regulation of cellular response to stress GO:0080135 244 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
muscle cell cellular homeostasis GO:0046716 3 0.013
neurotransmitter secretion GO:0007269 4 0.013
amide transport GO:0042886 76 0.013
compound eye development GO:0048749 1 0.013
osteoblast differentiation GO:0001649 92 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
morphogenesis of a polarized epithelium GO:0001738 3 0.013
response to biotic stimulus GO:0009607 276 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
monocarboxylic acid catabolic process GO:0072329 37 0.013
Mouse
small molecule biosynthetic process GO:0044283 157 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
cellular protein complex assembly GO:0043623 188 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.012
rho protein signal transduction GO:0007266 26 0.012
positive regulation of developmental process GO:0051094 314 0.012
Mouse
cellular protein catabolic process GO:0044257 261 0.012
chemical homeostasis GO:0048878 306 0.012
regulation of intracellular transport GO:0032386 195 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
protein acylation GO:0043543 138 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
protein processing GO:0016485 226 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
intracellular mrna localization GO:0008298 1 0.012
organic hydroxy compound catabolic process GO:1901616 22 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
defense response to other organism GO:0098542 129 0.012
response to other organism GO:0051707 261 0.012
nucleoside triphosphate catabolic process GO:0009143 394 0.012
ossification GO:0001503 121 0.012
regulation of growth rate GO:0040009 1 0.012
cranial nerve development GO:0021545 4 0.012
erk1 and erk2 cascade GO:0070371 104 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
organ formation GO:0048645 3 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
ribonucleoside catabolic process GO:0042454 406 0.012
meiotic chromosome segregation GO:0045132 4 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
protein import into nucleus GO:0006606 104 0.012
regulation of homeostatic process GO:0032844 121 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
mrna processing GO:0006397 133 0.011
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
nucleoside catabolic process GO:0009164 408 0.011
regulation of cellular component movement GO:0051270 334 0.011
secretion GO:0046903 254 0.011
dendritic cell differentiation GO:0097028 13 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
organic acid biosynthetic process GO:0016053 97 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
adult locomotory behavior GO:0008344 1 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
regulation of protein maturation GO:1903317 150 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
epithelium development GO:0060429 227 0.011
peptide transport GO:0015833 74 0.011
mating GO:0007618 1 0.011
meiosis i GO:0007127 4 0.011
neurogenesis GO:0022008 169 0.011
Mouse
rhythmic behavior GO:0007622 2 0.011
immune response GO:0006955 307 0.011
regulation of hormone levels GO:0010817 125 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
positive regulation of secretion GO:0051047 116 0.011
regulation of angiogenesis GO:0045765 92 0.011
microtubule based transport GO:0010970 21 0.011
cerebellum development GO:0021549 2 0.010
primary neural tube formation GO:0014020 3 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
thioester metabolic process GO:0035383 23 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
peptidyl serine modification GO:0018209 106 0.010
circadian behavior GO:0048512 2 0.010
dna repair GO:0006281 198 0.010
visual behavior GO:0007632 2 0.010
regulation of protein stability GO:0031647 87 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
regulation of protein processing GO:0070613 150 0.010
inner ear morphogenesis GO:0042472 4 0.010
positive regulation of transport GO:0051050 336 0.010
response to fungus GO:0009620 4 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
neural tube closure GO:0001843 3 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
myeloid leukocyte activation GO:0002274 34 0.010
negative regulation of stem cell proliferation GO:2000647 3 0.010
peptidyl lysine modification GO:0018205 144 0.010
cell adhesion GO:0007155 325 0.010
viral life cycle GO:0019058 132 0.010
signal release GO:0023061 70 0.010
anatomical structure homeostasis GO:0060249 100 0.010
protein targeting to nucleus GO:0044744 104 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010

PEX5 disease predictions

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 242 0.925
disease of metabolism DOID:0014667 295 0.925
lipid metabolism disorder DOID:3146 26 0.148
peroxisomal disease DOID:906 5 0.023
musculoskeletal system disease DOID:17 223 0.021
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
neurodegenerative disease DOID:1289 102 0.018
sensory system disease DOID:0050155 203 0.016
eye and adnexa disease DOID:1492 150 0.016
disease of cellular proliferation DOID:14566 174 0.015
cancer DOID:162 167 0.015
organ system cancer DOID:0050686 164 0.015
immune system disease DOID:2914 155 0.013
eye disease DOID:5614 149 0.012
muscle tissue disease DOID:66 113 0.011
muscular disease DOID:0080000 114 0.011
brain disease DOID:936 73 0.007
cerebral degeneration DOID:1443 16 0.002
leukodystrophy DOID:10579 8 0.001