Homo sapiens

13 known processes

PFDN6

prefoldin subunit 6

(Aliases: PFD6,MGC70744,HKE2,H2-KE2,KE-2)

PFDN6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.074
Worm
female gamete generation GO:0007292 2 0.060
cellular amino acid metabolic process GO:0006520 116 0.050
oogenesis GO:0048477 2 0.050
ncrna metabolic process GO:0034660 108 0.050
amine metabolic process GO:0009308 44 0.046
cellular amine metabolic process GO:0044106 41 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.041
rna processing GO:0006396 255 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.037
purine ribonucleoside metabolic process GO:0046128 437 0.037
regulation of cellular ketone metabolic process GO:0010565 50 0.036
membrane organization GO:0061024 292 0.036
purine nucleoside catabolic process GO:0006152 398 0.035
ribonucleoside triphosphate metabolic process GO:0009199 412 0.035
cellular ketone metabolic process GO:0042180 80 0.034
posttranscriptional regulation of gene expression GO:0010608 213 0.034
nucleoside triphosphate metabolic process GO:0009141 422 0.034
protein localization to organelle GO:0033365 280 0.034
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
cellular macromolecule catabolic process GO:0044265 380 0.032
vesicle mediated transport GO:0016192 371 0.032
Worm
carbohydrate derivative biosynthetic process GO:1901137 207 0.032
locomotory behavior GO:0007626 1 0.030
regulation of cell cycle GO:0051726 393 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.029
adult locomotory behavior GO:0008344 1 0.029
cellular lipid metabolic process GO:0044255 303 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
protein targeting GO:0006605 187 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
regulation of cell cycle process GO:0010564 266 0.027
determination of adult lifespan GO:0008340 2 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
ribonucleoside monophosphate metabolic process GO:0009161 187 0.026
lipid metabolic process GO:0006629 381 0.026
rna interference GO:0016246 4 0.026
protein catabolic process GO:0030163 325 0.025
single organism membrane organization GO:0044802 268 0.025
mrna metabolic process GO:0016071 175 0.025
organelle assembly GO:0070925 176 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.024
purine ribonucleotide catabolic process GO:0009154 404 0.023
interspecies interaction between organisms GO:0044419 156 0.023
negative regulation of programmed cell death GO:0043069 321 0.023
mitotic cell cycle GO:0000278 326 0.023
snrna metabolic process GO:0016073 15 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
cell morphogenesis GO:0000902 296 0.023
ncrna processing GO:0034470 83 0.022
cytoplasmic transport GO:0016482 379 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
neuromuscular junction development GO:0007528 3 0.021
glycoprotein metabolic process GO:0009100 110 0.021
lipid biosynthetic process GO:0008610 177 0.021
nucleus localization GO:0051647 1 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
regeneration GO:0031099 4 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
ras protein signal transduction GO:0007265 73 0.021
multicellular organismal aging GO:0010259 3 0.021
mrna processing GO:0006397 133 0.020
dna repair GO:0006281 198 0.020
mitotic cell cycle process GO:1903047 286 0.020
multi organism cellular process GO:0044764 156 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
nervous system development GO:0007399 293 0.019
Fly
purine nucleotide catabolic process GO:0006195 405 0.019
single organism cellular localization GO:1902580 332 0.019
ribonucleotide catabolic process GO:0009261 405 0.019
reproductive process GO:0022414 106 0.018
Worm
nuclear migration GO:0007097 1 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
organelle localization GO:0051640 84 0.018
cellular component morphogenesis GO:0032989 314 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
mitochondrion organization GO:0007005 156 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
negative regulation of cell death GO:0060548 345 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
nucleoside catabolic process GO:0009164 408 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
cell development GO:0048468 328 0.017
cell projection organization GO:0030030 252 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
endocytosis GO:0006897 159 0.017
Worm
regulation of cellular response to stress GO:0080135 244 0.017
small molecule biosynthetic process GO:0044283 157 0.017
purine containing compound catabolic process GO:0072523 411 0.017
response to other organism GO:0051707 261 0.017
positive regulation of programmed cell death GO:0043068 249 0.016
organophosphate catabolic process GO:0046434 430 0.016
atp metabolic process GO:0046034 176 0.016
response to external biotic stimulus GO:0043207 261 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
regulation of intracellular transport GO:0032386 195 0.016
biological adhesion GO:0022610 331 0.016
regulation of gene expression epigenetic GO:0040029 73 0.015
protein localization to membrane GO:0072657 160 0.015
endomembrane system organization GO:0010256 196 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
regulation of protein transport GO:0051223 213 0.015
nucleotide catabolic process GO:0009166 408 0.015
regulation of protein localization GO:0032880 296 0.015
negative regulation of cell cycle GO:0045786 193 0.015
cofactor metabolic process GO:0051186 87 0.015
protein ubiquitination GO:0016567 314 0.015
positive regulation of developmental process GO:0051094 314 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
cell adhesion GO:0007155 325 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
regulation of cell development GO:0060284 161 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
histone modification GO:0016570 251 0.014
cellular protein catabolic process GO:0044257 261 0.014
chromatin modification GO:0016568 298 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
segmentation GO:0035282 4 0.014
peripheral nervous system development GO:0007422 2 0.014
cilium assembly GO:0042384 63 0.014
defense response GO:0006952 315 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
response to virus GO:0009615 126 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
spermatid differentiation GO:0048515 4 0.013
cell part morphogenesis GO:0032990 137 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
rna modification GO:0009451 27 0.013
carbohydrate metabolic process GO:0005975 207 0.013
immune response GO:0006955 307 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of proteolysis GO:0030162 293 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
response to biotic stimulus GO:0009607 276 0.013
cellular protein complex assembly GO:0043623 188 0.013
establishment of organelle localization GO:0051656 59 0.013
cell projection morphogenesis GO:0048858 129 0.013
innate immune response GO:0045087 178 0.013
cellular component disassembly GO:0022411 92 0.013
regulation of cell growth GO:0001558 135 0.013
secretion GO:0046903 254 0.013
negative regulation of cell proliferation GO:0008285 228 0.012
positive regulation of catabolic process GO:0009896 310 0.012
fatty acid metabolic process GO:0006631 115 0.012
regulation of meiosis GO:0040020 3 0.012
rna splicing GO:0008380 131 0.012
regulation of kinase activity GO:0043549 314 0.012
response to oxygen containing compound GO:1901700 369 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
viral life cycle GO:0019058 132 0.012
nuclear division GO:0000280 128 0.012
regulation of transferase activity GO:0051338 355 0.012
neurogenesis GO:0022008 169 0.012
Fly
gtp metabolic process GO:0046039 239 0.012
transmembrane transport GO:0055085 399 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
secretion by cell GO:0032940 226 0.012
dephosphorylation GO:0016311 209 0.012
response to radiation GO:0009314 151 0.012
embryo development GO:0009790 123 0.012
Worm
guanosine containing compound metabolic process GO:1901068 244 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
chromatin organization GO:0006325 351 0.012
positive regulation of transport GO:0051050 336 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
generation of neurons GO:0048699 152 0.012
glycoprotein biosynthetic process GO:0009101 91 0.012
intracellular protein transport GO:0006886 270 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
meiotic chromosome segregation GO:0045132 4 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
wnt signaling pathway GO:0016055 156 0.011
gtp catabolic process GO:0006184 237 0.011
methylation GO:0032259 106 0.011
regulation of cell motility GO:2000145 299 0.011
mitotic nuclear division GO:0007067 119 0.011
rho protein signal transduction GO:0007266 26 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
microtubule based process GO:0007017 210 0.011
protein oligomerization GO:0051259 173 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
ribonucleoside monophosphate catabolic process GO:0009158 158 0.011
chromosome segregation GO:0007059 114 0.011
positive regulation of immune system process GO:0002684 283 0.011
regulation of viral process GO:0050792 103 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
positive regulation of cell death GO:0010942 263 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
peptidyl lysine modification GO:0018205 144 0.011
oocyte development GO:0048599 1 0.011
macromolecule methylation GO:0043414 97 0.011
maintenance of location GO:0051235 112 0.011
protein import GO:0017038 130 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
cell cycle phase transition GO:0044770 173 0.011
nuclear transport GO:0051169 179 0.011
organelle fission GO:0048285 149 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
protein acylation GO:0043543 138 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
regulation of cellular component movement GO:0051270 334 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
positive regulation of organelle organization GO:0010638 195 0.011
cell division GO:0051301 168 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
anterior posterior axis specification GO:0009948 2 0.011
regulation of endopeptidase activity GO:0052548 170 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
oocyte differentiation GO:0009994 2 0.010
protein processing GO:0016485 226 0.010
regulation of cell migration GO:0030334 289 0.010
negative regulation of protein maturation GO:1903318 142 0.010
dna catabolic process GO:0006308 49 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
monocarboxylic acid metabolic process GO:0032787 185 0.010
sex differentiation GO:0007548 45 0.010
Worm
covalent chromatin modification GO:0016569 254 0.010
blastoderm segmentation GO:0007350 2 0.010
alcohol metabolic process GO:0006066 114 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
microtubule organizing center organization GO:0031023 62 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010

PFDN6 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.037
eye and adnexa disease DOID:1492 150 0.037
nervous system disease DOID:863 431 0.037
disease of cellular proliferation DOID:14566 174 0.034
eye disease DOID:5614 149 0.033
cancer DOID:162 167 0.029
organ system cancer DOID:0050686 164 0.029
retinal disease DOID:5679 118 0.018
retinal degeneration DOID:8466 89 0.018
disease of metabolism DOID:0014667 295 0.015
musculoskeletal system disease DOID:17 223 0.014
central nervous system disease DOID:331 186 0.013
myopathy DOID:423 104 0.011
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011
inherited metabolic disorder DOID:655 242 0.010