|
|
bicarbonate transport
|
GO:0015701 |
6 |
1.000
|
|
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
47 |
0.991
|
Human |
|
|
chloride transport
|
GO:0006821 |
41 |
0.940
|
Human |
|
|
regulation of guanylate cyclase activity
|
GO:0031282 |
2 |
0.934
|
Human |
|
|
chloride transmembrane transport
|
GO:1902476 |
38 |
0.907
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.884
|
Human Rat |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.829
|
Human |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.810
|
Human |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.762
|
Human |
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.740
|
Human |
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.708
|
Human |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.704
|
Human |
|
|
modified amino acid transport
|
GO:0072337 |
11 |
0.702
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.675
|
Human |
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.660
|
Human |
|
|
membrane hyperpolarization
|
GO:0060081 |
1 |
0.638
|
|
|
|
regulation of vasodilation
|
GO:0042312 |
4 |
0.565
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.551
|
|
|
|
system process
|
GO:0003008 |
349 |
0.549
|
Human Mouse |
|
|
microvillus organization
|
GO:0032528 |
2 |
0.502
|
Human |
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.490
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.460
|
Human |
|
|
regulation of anion channel activity
|
GO:0010359 |
2 |
0.456
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.444
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.417
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.416
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.406
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.391
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.377
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.375
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.363
|
Human |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.362
|
Human |
|
|
oxalate transport
|
GO:0019532 |
3 |
0.351
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.345
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.332
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.312
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
76 |
0.306
|
Human |
|
|
inorganic anion transport
|
GO:0015698 |
60 |
0.305
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.305
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.296
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.292
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.287
|
|
|
|
transepithelial transport
|
GO:0070633 |
9 |
0.285
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.279
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.278
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.276
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.274
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.273
|
Mouse |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.268
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.242
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.230
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.228
|
Human |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.225
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.222
|
|
|
|
amino acid betaine transport
|
GO:0015838 |
4 |
0.221
|
Human |
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.221
|
Human |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.220
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.216
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.213
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.212
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.210
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.210
|
|
|
|
negative regulation of cgmp metabolic process
|
GO:0030824 |
1 |
0.209
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.208
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.205
|
Human |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.203
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.195
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.193
|
Human |
|
|
tissue migration
|
GO:0090130 |
119 |
0.192
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.190
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.186
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.185
|
Human |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.185
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.185
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.183
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.180
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.179
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.179
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
0.177
|
|
|
|
renal system process
|
GO:0003014 |
25 |
0.177
|
Human |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.176
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.174
|
Human |
|
|
blood circulation
|
GO:0008015 |
113 |
0.173
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.173
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.168
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.168
|
Human |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.167
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.165
|
|
|
|
regulation of chloride transport
|
GO:2001225 |
2 |
0.165
|
|
|
|
negative regulation of nucleotide biosynthetic process
|
GO:0030809 |
11 |
0.163
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.158
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.157
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.153
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.153
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.148
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.147
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.146
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.146
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.144
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.141
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.141
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.141
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.139
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.138
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.137
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.136
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.135
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.134
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.132
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.130
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.128
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.127
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.127
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.126
|
|
|
|
negative regulation of cyclic nucleotide biosynthetic process
|
GO:0030803 |
10 |
0.125
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.124
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.121
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.120
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.119
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.118
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.117
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.115
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.115
|
Human |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.114
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.114
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
2 |
0.114
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.113
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.113
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.113
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.113
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.111
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.111
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.110
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.110
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.109
|
Human |
|
|
regulation of male gonad development
|
GO:2000018 |
4 |
0.108
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.108
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.107
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.107
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.107
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.107
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.107
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.106
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.104
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.103
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.102
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.101
|
Human |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.101
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.100
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.100
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.099
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.098
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.098
|
|
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.097
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.097
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.097
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.096
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.096
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.096
|
Human |
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.094
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.094
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.094
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.094
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
3 |
0.093
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.093
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.092
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.091
|
|
|
|
negative regulation of cyclase activity
|
GO:0031280 |
6 |
0.091
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.089
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.088
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.088
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.087
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.087
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.087
|
Human |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.087
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.086
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.086
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.085
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.085
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.085
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.085
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.084
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.084
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.084
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.084
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.083
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.083
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.082
|
|
|
|
regulation of cgmp metabolic process
|
GO:0030823 |
9 |
0.081
|
Human |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.080
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.080
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.080
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.080
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.080
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.080
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.079
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.079
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.079
|
|
|
|
fluid transport
|
GO:0042044 |
6 |
0.079
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.079
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.078
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.077
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.077
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.076
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.076
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.076
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.075
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.074
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.074
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.073
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.073
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.072
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.072
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.072
|
|
|
|
sulfate transmembrane transport
|
GO:1902358 |
3 |
0.072
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.071
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.071
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.071
|
|
|
|
positive regulation of male gonad development
|
GO:2000020 |
3 |
0.071
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.070
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.070
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.070
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.070
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.069
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.069
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.067
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.067
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.067
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.067
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.066
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.066
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.066
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.065
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.065
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.064
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.064
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.063
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.063
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.063
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.063
|
Human Mouse |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.063
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.062
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.062
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.062
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.062
|
|
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.061
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.061
|
|
|
|
inner ear development
|
GO:0048839 |
8 |
0.061
|
Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.060
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.060
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.060
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.060
|
|
|
|
positive regulation of protein targeting to membrane
|
GO:0090314 |
8 |
0.059
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.059
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.059
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.058
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.058
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.058
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.057
|
Human |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.057
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.057
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.057
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.056
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.056
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.056
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.056
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.056
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.055
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.055
|
|
|
|
transepithelial chloride transport
|
GO:0030321 |
3 |
0.055
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.055
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.055
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.054
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.054
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.054
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.054
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.053
|
Human |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.053
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.053
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.053
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.053
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.053
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.053
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.052
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.052
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.052
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.051
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.051
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.051
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.051
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.050
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.050
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.050
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.049
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.049
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.049
|
|
|
|
sodium ion homeostasis
|
GO:0055078 |
14 |
0.049
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
32 |
0.049
|
Human |
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.048
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.048
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.048
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.048
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.048
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.048
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.048
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.048
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.048
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.048
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.048
|
Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.048
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.047
|
|
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.047
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.047
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.047
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.047
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.046
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.046
|
|
|
|
growth
|
GO:0040007 |
202 |
0.046
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.046
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.046
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.046
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
29 |
0.045
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.045
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.044
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.044
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.044
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.044
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.044
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.043
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.043
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.043
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.043
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.043
|
|
|
|
positive regulation of mesenchymal stem cell differentiation
|
GO:2000741 |
4 |
0.043
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.042
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.042
|
|
|
|
metanephric nephron epithelium development
|
GO:0072243 |
4 |
0.042
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.041
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.041
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.041
|
Human |
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.041
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.041
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.041
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.041
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.041
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.041
|
|
|
|
protein nitrosylation
|
GO:0017014 |
1 |
0.040
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.040
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.040
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.039
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.039
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.039
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.039
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.039
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.039
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.039
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.039
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.039
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.039
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.038
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.038
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.038
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.038
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.037
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.037
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.037
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.037
|
|
|
|
metanephric nephron tubule development
|
GO:0072234 |
3 |
0.037
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.037
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.036
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.036
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.036
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.036
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.036
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.036
|
|
|
|
respiratory burst involved in defense response
|
GO:0002679 |
2 |
0.036
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.036
|
|
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.036
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.035
|
|
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.035
|
|
|
|
regulation of actin filament based movement
|
GO:1903115 |
24 |
0.035
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.035
|
Human |
|
|
cardiac muscle cell action potential
|
GO:0086001 |
23 |
0.035
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.035
|
Human |
|
|
hippo signaling
|
GO:0035329 |
20 |
0.035
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.034
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.034
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.034
|
|
|
|
water transport
|
GO:0006833 |
6 |
0.034
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.034
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.034
|
|
|
|
foramen ovale closure
|
GO:0035922 |
1 |
0.034
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.034
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.033
|
|
|
|
response to sucrose
|
GO:0009744 |
1 |
0.033
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.033
|
Human |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.033
|
Human |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.033
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.033
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.033
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.032
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.032
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.032
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.032
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.032
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.032
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.032
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.032
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.032
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.031
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.031
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.031
|
Human |
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.031
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.031
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.031
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.031
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.031
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.031
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.031
|
|
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.031
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.031
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.031
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.031
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.031
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.031
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.030
|
|
|
|
memory
|
GO:0007613 |
3 |
0.030
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.030
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.030
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.030
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.030
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.030
|
|
|
|
cellular phosphate ion homeostasis
|
GO:0030643 |
4 |
0.030
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.030
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.030
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.030
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.030
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.030
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.030
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.029
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.029
|
|
|
|
regulation of peptidyl cysteine s nitrosylation
|
GO:2000169 |
1 |
0.029
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.029
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.029
|
|
|
|
negative regulation of leukocyte degranulation
|
GO:0043301 |
1 |
0.029
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.029
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.029
|
|
|
|
ear development
|
GO:0043583 |
14 |
0.028
|
Rat |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.028
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
28 |
0.028
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.028
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.028
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.028
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.028
|
Mouse |
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.028
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.028
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.028
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.028
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.028
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.028
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.028
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.027
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.027
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.027
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.027
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.027
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.027
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.027
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.027
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.027
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.027
|
|
|
|
chondrocyte differentiation involved in endochondral bone morphogenesis
|
GO:0003413 |
1 |
0.027
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.027
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.026
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.026
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.026
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.026
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.026
|
|
|
|
translation
|
GO:0006412 |
132 |
0.026
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.026
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.026
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.026
|
Human |
|
|
organ formation
|
GO:0048645 |
3 |
0.026
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.026
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.026
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.026
|
|
