Homo sapiens

302 known processes

APC

adenomatous polyposis coli

(Aliases: GS,DP2.5,DP3,BTPS2,DP2)

APC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neural tube formation GO:0001841 3 0.999
pharynx development GO:0060465 1 0.999
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.998
Fly
microtubule cytoskeleton organization GO:0000226 176 0.998
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.996
Fly
regulation of microtubule cytoskeleton organization GO:0070507 61 0.995
locomotory behavior GO:0007626 1 0.994
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.993
digestive system development GO:0055123 75 0.993
Worm
maintenance of cell polarity GO:0030011 2 0.993
regulation of wnt signaling pathway GO:0030111 123 0.993
regulation of microtubule based process GO:0032886 74 0.993
cardiac cell fate specification GO:0060912 1 0.991
hindlimb morphogenesis GO:0035137 2 0.991
cell fate determination GO:0001709 3 0.990
microtubule based process GO:0007017 210 0.990
positive regulation of axon extension GO:0045773 4 0.990
digestive tract development GO:0048565 75 0.987
Worm
cerebral cortex radially oriented cell migration GO:0021799 1 0.986
morphogenesis of embryonic epithelium GO:0016331 4 0.986
regulation of cell differentiation GO:0045595 393 0.985
Mouse Fly
stem cell differentiation GO:0048863 93 0.985
Mouse
taxis GO:0042330 157 0.985
Fly
tube morphogenesis GO:0035239 95 0.984
Worm
gastrulation GO:0007369 51 0.984
Worm
formation of primary germ layer GO:0001704 42 0.982
Worm
protein localization to adherens junction GO:0071896 2 0.982
positive regulation of wnt signaling pathway GO:0030177 54 0.982
Worm
embryonic epithelial tube formation GO:0001838 4 0.981
anatomical structure formation involved in morphogenesis GO:0048646 284 0.981
Worm Fly
oogenesis GO:0048477 2 0.973
Fly
regulation of canonical wnt signaling pathway GO:0060828 88 0.973
intracellular protein transport GO:0006886 270 0.971
Human Worm Fly
protein localization to nucleus GO:0034504 136 0.970
Human
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.963
negative regulation of cell proliferation GO:0008285 228 0.958
cell junction organization GO:0034330 79 0.958
regulation of embryonic development GO:0045995 20 0.958
Worm
canonical wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition GO:0044334 2 0.953
regulation of locomotion GO:0040012 329 0.950
tissue morphogenesis GO:0048729 96 0.946
neuron differentiation GO:0030182 138 0.944
Mouse Rat Fly
female gamete generation GO:0007292 2 0.939
Fly
stem cell development GO:0048864 69 0.937
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.937
embryonic forelimb morphogenesis GO:0035115 4 0.936
head development GO:0060322 108 0.928
Fly
morphogenesis of a polarized epithelium GO:0001738 3 0.918
heart formation GO:0060914 2 0.916
post embryonic development GO:0009791 2 0.913
Worm Fly
cell migration involved in gastrulation GO:0042074 1 0.913
cardiac muscle cell contraction GO:0086003 4 0.912
enzyme linked receptor protein signaling pathway GO:0007167 303 0.912
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.907
microtubule polymerization or depolymerization GO:0031109 37 0.905
cerebral cortex cell migration GO:0021795 3 0.898
primary neural tube formation GO:0014020 3 0.897
response to wounding GO:0009611 168 0.893
establishment of apical basal cell polarity GO:0035089 1 0.887
wnt signaling pathway GO:0016055 156 0.878
canonical wnt signaling pathway GO:0060070 116 0.877
protein localization to organelle GO:0033365 280 0.875
Human
rho protein signal transduction GO:0007266 26 0.873
chemotaxis GO:0006935 157 0.871
Fly
intermediate filament cytoskeleton organization GO:0045104 17 0.869
single organism cellular localization GO:1902580 332 0.866
Human
purine ribonucleoside catabolic process GO:0046130 398 0.865
establishment of organelle localization GO:0051656 59 0.865
Fly
digestive tract morphogenesis GO:0048546 56 0.865
Worm
positive regulation of proteoglycan biosynthetic process GO:1902730 3 0.864
cellular response to endogenous stimulus GO:0071495 336 0.862
Rat
single organismal cell cell adhesion GO:0016337 148 0.860
Fly
establishment of monopolar cell polarity GO:0061162 1 0.860
embryonic morphogenesis GO:0048598 85 0.858
Worm Fly
establishment of cell polarity GO:0030010 22 0.851
tube development GO:0035295 125 0.848
Worm
neural tube development GO:0021915 9 0.846
establishment or maintenance of monopolar cell polarity GO:0061339 1 0.845
embryo development GO:0009790 123 0.838
Worm Fly
positive regulation of cell development GO:0010720 92 0.836
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 1 0.833
regulation of anatomical structure morphogenesis GO:0022603 286 0.831
Mouse Worm Fly
hindbrain development GO:0030902 3 0.831
Fly
plasma membrane organization GO:0007009 115 0.830
negative regulation of cell fate specification GO:0009996 3 0.827
cytoplasmic transport GO:0016482 379 0.825
Human Worm
regulation of cell motility GO:2000145 299 0.821
endomembrane system organization GO:0010256 196 0.821
regulation of cell cycle GO:0051726 393 0.821
heart induction GO:0003129 4 0.819
mating GO:0007618 1 0.818
axon cargo transport GO:0008088 2 0.809
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.809
ras protein signal transduction GO:0007265 73 0.805
posttranscriptional regulation of gene expression GO:0010608 213 0.804
cell junction assembly GO:0034329 67 0.802
muscle structure development GO:0061061 98 0.796
neuroblast proliferation GO:0007405 4 0.792
Fly
negative regulation of wnt signaling pathway GO:0030178 69 0.791
establishment or maintenance of cell polarity GO:0007163 31 0.783
Rat Fly
cerebral cortex radial glia guided migration GO:0021801 1 0.779
regulation of cardioblast differentiation GO:0051890 4 0.779
protein import into nucleus GO:0006606 104 0.778
Human
heart field specification GO:0003128 2 0.778
positive regulation of cell death GO:0010942 263 0.772
axon extension GO:0048675 13 0.769
positive regulation of heparan sulfate proteoglycan biosynthetic process GO:0010909 3 0.766
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.765
purine containing compound catabolic process GO:0072523 411 0.765
positive regulation of intracellular protein transport GO:0090316 76 0.764
nucleoside catabolic process GO:0009164 408 0.761
brain development GO:0007420 97 0.757
Fly
intermediate filament based process GO:0045103 17 0.756
nucleocytoplasmic transport GO:0006913 176 0.756
Human Worm
single organism nuclear import GO:1902593 104 0.754
Human
cardiac muscle cell cardiac muscle cell adhesion GO:0086042 1 0.751
cell cell junction assembly GO:0007043 25 0.749
nervous system development GO:0007399 293 0.744
Mouse Rat Fly
desmosome assembly GO:0002159 4 0.739
regulation of cell development GO:0060284 161 0.736
Fly
epithelial tube morphogenesis GO:0060562 38 0.734
gland morphogenesis GO:0022612 8 0.728
cellular protein complex assembly GO:0043623 188 0.727
Mouse
mitotic cell cycle process GO:1903047 286 0.714
central nervous system development GO:0007417 123 0.712
Fly
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.711
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.709
regulation of cytoskeleton organization GO:0051493 177 0.709
establishment of spindle orientation GO:0051294 9 0.708
protein localization to plasma membrane GO:0072659 93 0.708
vesicle mediated transport GO:0016192 371 0.705
Worm
cell cell junction organization GO:0045216 69 0.702
synaptic vesicle transport GO:0048489 5 0.701
guanosine containing compound metabolic process GO:1901068 244 0.696
apical junction assembly GO:0043297 19 0.694
directional locomotion GO:0033058 1 0.694
anterior posterior axis specification GO:0009948 2 0.693
establishment of nucleus localization GO:0040023 1 0.691
Fly
ameboidal type cell migration GO:0001667 135 0.690
nephron tubule epithelial cell differentiation GO:0072160 3 0.685
protein localization to membrane GO:0072657 160 0.683
photoreceptor cell differentiation GO:0046530 2 0.681
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.676
biological adhesion GO:0022610 331 0.676
Mouse Fly
generation of neurons GO:0048699 152 0.673
Mouse Rat Fly
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 2 0.672
microtubule based movement GO:0007018 32 0.672
protein targeting to nucleus GO:0044744 104 0.671
Human
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.667
establishment of protein localization to membrane GO:0090150 121 0.663
somatic stem cell maintenance GO:0035019 4 0.659
Mouse
cardiac muscle cell action potential GO:0086001 23 0.659
regulation of heart induction GO:0090381 2 0.657
cell development GO:0048468 328 0.656
Mouse Rat Fly
mitotic cell cycle GO:0000278 326 0.651
wound healing GO:0042060 115 0.645
cell morphogenesis involved in differentiation GO:0000904 144 0.643
Mouse Fly
organelle localization GO:0051640 84 0.630
Fly
organ induction GO:0001759 4 0.622
ribonucleotide catabolic process GO:0009261 405 0.606
regulation of establishment of protein localization GO:0070201 242 0.597
Human
microtubule polymerization GO:0046785 18 0.591
Mouse
epithelial tube formation GO:0072175 5 0.590
nuclear transport GO:0051169 179 0.581
Human Worm
negative regulation of catagen GO:0051796 1 0.573
system process GO:0003008 349 0.572
cytoskeleton dependent intracellular transport GO:0030705 21 0.567
segmentation GO:0035282 4 0.563
regulation of smoothened signaling pathway GO:0008589 6 0.563
epithelial cell differentiation GO:0030855 141 0.560
Mouse
regulation of protein localization GO:0032880 296 0.559
oocyte differentiation GO:0009994 2 0.553
negative regulation of cell fate commitment GO:0010454 3 0.552
cell morphogenesis GO:0000902 296 0.551
Mouse Worm Fly
regulation of nervous system development GO:0051960 88 0.548
somitogenesis GO:0001756 2 0.539
response to oxygen containing compound GO:1901700 369 0.538
Rat
hair follicle morphogenesis GO:0031069 2 0.524
nuclear division GO:0000280 128 0.523
positive regulation of programmed cell death GO:0043068 249 0.518
microtubule organizing center organization GO:0031023 62 0.511
regulation of intracellular protein transport GO:0033157 123 0.508
Human
regulation of organ formation GO:0003156 4 0.502
neuron migration GO:0001764 11 0.495
positive regulation of cellular component organization GO:0051130 376 0.492
epithelium development GO:0060429 227 0.487
Mouse
modification dependent protein catabolic process GO:0019941 209 0.487
establishment of protein localization to plasma membrane GO:0090002 68 0.484
neurogenesis GO:0022008 169 0.480
Mouse Rat Fly
positive regulation of keratinocyte proliferation GO:0010838 4 0.474
proteoglycan biosynthetic process GO:0030166 20 0.471
negative regulation of cellular protein metabolic process GO:0032269 353 0.471
ribonucleoside triphosphate catabolic process GO:0009203 391 0.462
regulation of melanosome transport GO:1902908 1 0.460
small gtpase mediated signal transduction GO:0007264 78 0.456
cell projection morphogenesis GO:0048858 129 0.448
Mouse Fly
negative regulation of apoptotic process GO:0043066 316 0.445
Mouse
sensory organ morphogenesis GO:0090596 21 0.443
Fly
oocyte development GO:0048599 1 0.441
positive regulation of transport GO:0051050 336 0.439
regulation of cell cycle process GO:0010564 266 0.438
cellular response to nitrogen compound GO:1901699 144 0.436
peptidyl threonine modification GO:0018210 45 0.435
nucleoside triphosphate metabolic process GO:0009141 422 0.430
nephron tubule formation GO:0072079 1 0.427
regulation of determination of dorsal identity GO:2000015 2 0.423
sensory organ development GO:0007423 52 0.422
Mouse Fly
chordate embryonic development GO:0043009 34 0.418
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.418
tube closure GO:0060606 3 0.417
nucleoside phosphate catabolic process GO:1901292 412 0.415
anterior posterior axis specification embryo GO:0008595 2 0.415
regulation of stress activated mapk cascade GO:0032872 84 0.415
synaptic transmission GO:0007268 61 0.406
regulation of mitotic cell cycle GO:0007346 189 0.405
neural tube closure GO:0001843 3 0.401
regulation of intracellular transport GO:0032386 195 0.401
Human
embryonic skeletal joint morphogenesis GO:0060272 2 0.398
endocytosis GO:0006897 159 0.398
Worm
sex differentiation GO:0007548 45 0.397
morphogenesis of an epithelium GO:0002009 60 0.396
eye development GO:0001654 42 0.395
Mouse Fly
smoothened signaling pathway GO:0007224 14 0.393
negative regulation of cardioblast cell fate specification GO:0009997 1 0.393
establishment of tissue polarity GO:0007164 3 0.392
metencephalon development GO:0022037 2 0.391
establishment of planar polarity GO:0001736 3 0.389
regulation of protein catabolic process GO:0042176 155 0.387
cellular component morphogenesis GO:0032989 314 0.386
Mouse Worm Fly
multicellular organismal signaling GO:0035637 34 0.383
response to nitrogen compound GO:1901698 184 0.379
behavior GO:0007610 112 0.378
regulation of membrane potential GO:0042391 95 0.376
positive regulation of synaptic transmission GO:0050806 4 0.372
positive regulation of apoptotic process GO:0043065 246 0.369
positive regulation of gtpase activity GO:0043547 166 0.367
positive regulation of gtp catabolic process GO:0033126 166 0.366
endodermal cell fate specification GO:0001714 4 0.366
Worm
axonogenesis GO:0007409 31 0.365
Mouse Fly
convergent extension GO:0060026 1 0.364
negative regulation of cell differentiation GO:0045596 171 0.359
Mouse Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.358
centrosome cycle GO:0007098 32 0.357
embryonic skeletal joint development GO:0072498 2 0.356
purine nucleotide catabolic process GO:0006195 405 0.355
extrinsic apoptotic signaling pathway GO:0097191 119 0.354
mesenchymal cell development GO:0014031 50 0.354
regionalization GO:0003002 29 0.350
Mouse Fly
endoderm development GO:0007492 33 0.348
Worm
nucleus organization GO:0006997 28 0.346
smooth muscle cell differentiation GO:0051145 8 0.346
heparan sulfate proteoglycan biosynthetic process GO:0015012 8 0.344
negative regulation of developmental process GO:0051093 247 0.343
Mouse Worm Fly
positive regulation of neuroblast proliferation GO:0002052 2 0.341
regulation of apoptotic signaling pathway GO:2001233 175 0.335
renal vesicle development GO:0072087 4 0.335
protein targeting GO:0006605 187 0.329
Human
regulation of protein complex assembly GO:0043254 147 0.329
Mouse Fly
negative regulation of organelle organization GO:0010639 126 0.328
maintenance of location GO:0051235 112 0.328
cell division GO:0051301 168 0.324
muscle cell differentiation GO:0042692 63 0.323
mesenchymal cell differentiation GO:0048762 52 0.322
purine ribonucleotide catabolic process GO:0009154 404 0.320
negative regulation of glial cell differentiation GO:0045686 1 0.319
cell adhesion GO:0007155 325 0.317
Mouse Fly
microtubule depolymerization GO:0007019 18 0.314
regulation of rho protein signal transduction GO:0035023 79 0.313
establishment of protein localization to organelle GO:0072594 172 0.306
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.304
ribonucleoside triphosphate metabolic process GO:0009199 412 0.298
embryonic digestive tract morphogenesis GO:0048557 2 0.297
developmental programmed cell death GO:0010623 3 0.294
Fly
rna localization GO:0006403 41 0.291
regulation of endothelial cell differentiation GO:0045601 4 0.291
nucleus localization GO:0051647 1 0.290
Fly
cell cell signaling GO:0007267 155 0.287
forebrain generation of neurons GO:0021872 3 0.286
stress activated protein kinase signaling cascade GO:0031098 94 0.283
protein localization to cell junction GO:1902414 3 0.280
developmental growth involved in morphogenesis GO:0060560 23 0.278
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.277
regulation of cell morphogenesis GO:0022604 153 0.274
Worm
positive regulation of protein import into nucleus GO:0042307 46 0.273
single organism cell adhesion GO:0098602 179 0.270
Fly
embryonic hindlimb morphogenesis GO:0035116 2 0.268
regulation of transferase activity GO:0051338 355 0.267
regulation of glycoprotein biosynthetic process GO:0010559 14 0.266
regulation of glycoprotein metabolic process GO:1903018 19 0.266
protein complex disassembly GO:0043241 52 0.266
positive regulation of determination of dorsal identity GO:2000017 1 0.265
cellular response to organonitrogen compound GO:0071417 124 0.264
regulation of nucleocytoplasmic transport GO:0046822 98 0.263
Human
adult locomotory behavior GO:0008344 1 0.261
sensory perception of sound GO:0007605 37 0.259
positive regulation of protein transport GO:0051222 135 0.259
specification of axis polarity GO:0065001 1 0.258
epidermis morphogenesis GO:0048730 3 0.257
neurological system process GO:0050877 163 0.257
intracellular mrna localization GO:0008298 1 0.256
regulation of neural precursor cell proliferation GO:2000177 4 0.256
nuclear export GO:0051168 69 0.256
Worm
negative regulation of phosphate metabolic process GO:0045936 267 0.255
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.254
regulation of mitotic cell cycle phase transition GO:1901990 118 0.253
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.248
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.247
regulation of protein import into nucleus GO:0042306 78 0.246
Human
mesoderm morphogenesis GO:0048332 11 0.246
regulation of mitosis GO:0007088 63 0.245
multicellular organismal reproductive process GO:0048609 40 0.244
Fly
developmental cell growth GO:0048588 18 0.243
regulation of neurogenesis GO:0050767 82 0.243
regulation of cellular component size GO:0032535 82 0.242
regulation of neuroblast proliferation GO:1902692 3 0.238
microtubule based transport GO:0010970 21 0.236
gene silencing by rna GO:0031047 26 0.235
neuron projection extension GO:1990138 14 0.235
pattern specification process GO:0007389 43 0.234
Mouse Fly
protein modification by small protein removal GO:0070646 92 0.234
endoderm formation GO:0001706 33 0.233
Worm
regulation of cell matrix adhesion GO:0001952 42 0.233
epithelial cell migration GO:0010631 119 0.231
regulation of protein depolymerization GO:1901879 22 0.230
single organism reproductive process GO:0044702 98 0.228
Mouse Fly
positive regulation of intracellular transport GO:0032388 104 0.227
positive regulation of smoothened signaling pathway GO:0045880 4 0.222
golgi vesicle transport GO:0048193 80 0.221
regulation of cell adhesion GO:0030155 166 0.221
Mouse
inner ear morphogenesis GO:0042472 4 0.220
positive regulation of cell cycle GO:0045787 140 0.220
positive regulation of embryonic development GO:0040019 6 0.218
negative regulation of embryonic development GO:0045992 4 0.217
cell projection organization GO:0030030 252 0.215
protein import GO:0017038 130 0.215
Human
regulation of heparan sulfate proteoglycan biosynthetic process GO:0010908 3 0.214
cellular component disassembly GO:0022411 92 0.214
negative regulation of protein depolymerization GO:1901880 17 0.213
negative regulation of peptidase activity GO:0010466 91 0.212
immune system development GO:0002520 195 0.210
Mouse
action potential GO:0001508 34 0.208
neuron projection guidance GO:0097485 12 0.208
Fly
regulation of rho gtpase activity GO:0032319 66 0.205
regulation of extent of cell growth GO:0061387 9 0.205
positive regulation of sulfur metabolic process GO:0051176 3 0.202
cardiac conduction GO:0061337 23 0.201
regulation of epithelial cell proliferation GO:0050678 113 0.200
Mouse
centromeric sister chromatid cohesion GO:0070601 3 0.200
regulation of system process GO:0044057 101 0.200
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.199
embryonic organ development GO:0048568 36 0.198
positive regulation of protein kinase activity GO:0045860 190 0.198
blastoderm segmentation GO:0007350 2 0.198
sensory perception GO:0007600 103 0.198
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.198
negative regulation of protein complex disassembly GO:0043242 20 0.198
regulation of actin filament based movement GO:1903115 24 0.198
organelle fission GO:0048285 149 0.197
regulation of cardiac muscle cell contraction GO:0086004 23 0.197
regulation of multi organism process GO:0043900 157 0.196
regulation of glucokinase activity GO:0033131 2 0.195
smooth muscle cell proliferation GO:0048659 28 0.193
cellular response to oxygen containing compound GO:1901701 276 0.192
establishment of vesicle localization GO:0051650 23 0.191
positive regulation of cell growth GO:0030307 48 0.190
modification dependent macromolecule catabolic process GO:0043632 212 0.190
reproductive system development GO:0061458 56 0.190
Mouse
response to growth factor GO:0070848 205 0.189
Rat
positive regulation of cytoplasmic transport GO:1903651 82 0.189
regulation of epithelial to mesenchymal transition GO:0010717 37 0.189
establishment of endothelial blood brain barrier GO:0014045 1 0.189
protein catabolic process GO:0030163 325 0.185
centrosome separation GO:0051299 3 0.185
neural tube patterning GO:0021532 2 0.184
salivary gland morphogenesis GO:0007435 4 0.184
cell part morphogenesis GO:0032990 137 0.184
Mouse Fly
gonad development GO:0008406 34 0.183
regulation of cellular component movement GO:0051270 334 0.182
negative regulation of smoothened signaling pathway GO:0045879 3 0.182
positive regulation of nervous system development GO:0051962 54 0.181
response to lipid GO:0033993 206 0.180
cell communication involved in cardiac conduction GO:0086065 18 0.179
regulation of dna metabolic process GO:0051052 153 0.177
ubiquitin dependent protein catabolic process GO:0006511 206 0.177
ventricular cardiac muscle cell action potential GO:0086005 15 0.177
maintenance of location in cell GO:0051651 62 0.177
positive regulation of rho gtpase activity GO:0032321 56 0.177
bundle of his cell to purkinje myocyte communication GO:0086069 8 0.174
regulation of chromosome segregation GO:0051983 44 0.173
regulation of heart rate GO:0002027 38 0.171
organophosphate catabolic process GO:0046434 430 0.171
reproductive structure development GO:0048608 55 0.170
Mouse
tripartite regional subdivision GO:0007351 2 0.168
multicellular organismal homeostasis GO:0048871 67 0.167
cell fate commitment involved in formation of primary germ layer GO:0060795 6 0.166
Worm
cell substrate adhesion GO:0031589 132 0.165
chemical homeostasis GO:0048878 306 0.165
cellular protein catabolic process GO:0044257 261 0.164
synaptic vesicle localization GO:0097479 5 0.163
single organism carbohydrate metabolic process GO:0044723 193 0.161
eye photoreceptor cell differentiation GO:0001754 2 0.160
actin filament based process GO:0030029 224 0.160
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.159
maintenance of protein location GO:0045185 57 0.156
dendrite development GO:0016358 24 0.156
apoptotic signaling pathway GO:0097190 268 0.153
reproductive process GO:0022414 106 0.151
Mouse Fly
regulation of epithelial cell differentiation involved in kidney development GO:2000696 4 0.149
negative regulation of apoptotic signaling pathway GO:2001234 97 0.148
cell fate commitment GO:0045165 27 0.147
Worm
adherens junction assembly GO:0034333 34 0.146
nuclear import GO:0051170 106 0.145
Human
regulation of cellular protein catabolic process GO:1903362 96 0.145
positive regulation of kinase activity GO:0033674 204 0.145
actin cytoskeleton organization GO:0030036 207 0.145
Fly
receptor mediated endocytosis GO:0006898 84 0.145
cell type specific apoptotic process GO:0097285 125 0.144
embryonic organ morphogenesis GO:0048562 24 0.144
multicellular organism reproduction GO:0032504 42 0.144
Fly
peptidyl threonine phosphorylation GO:0018107 41 0.143
regulation of protein targeting GO:1903533 91 0.142
Human
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.141
positive regulation of mapk cascade GO:0043410 190 0.141
negative regulation of cardiac cell fate specification GO:2000044 1 0.140
multi organism reproductive process GO:0044703 54 0.139
Fly
hair cell differentiation GO:0035315 2 0.138
regulation of cellular ketone metabolic process GO:0010565 50 0.136
Rat
specification of organ identity GO:0010092 3 0.135
developmental induction GO:0031128 5 0.134
erk1 and erk2 cascade GO:0070371 104 0.134
posttranscriptional gene silencing by rna GO:0035194 25 0.134
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.132
post golgi vesicle mediated transport GO:0006892 36 0.131
mitochondrion transport along microtubule GO:0047497 3 0.131
stem cell maintenance GO:0019827 19 0.130
Mouse
glycoprotein biosynthetic process GO:0009101 91 0.129
regulation of gtp catabolic process GO:0033124 180 0.129
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.129
chromatin modification GO:0016568 298 0.129
skin development GO:0043588 76 0.129
Mouse
tube formation GO:0035148 10 0.128
cellular response to lipid GO:0071396 127 0.128
cell growth GO:0016049 160 0.127
spindle organization GO:0007051 53 0.127
Worm
response to hormone GO:0009725 175 0.127
mesenchyme development GO:0060485 59 0.127
protein localization to cytoskeleton GO:0044380 11 0.126
cerebellum development GO:0021549 2 0.126
nucleotide catabolic process GO:0009166 408 0.126
maintenance of protein location in cell GO:0032507 56 0.126
glycosyl compound catabolic process GO:1901658 413 0.125
apoptotic process involved in morphogenesis GO:0060561 3 0.125
developmental growth GO:0048589 48 0.125
sensory perception of mechanical stimulus GO:0050954 37 0.125
regulation of sulfur metabolic process GO:0042762 5 0.124
regulation of centromeric sister chromatid cohesion GO:0070602 2 0.124
regulation of cell projection organization GO:0031344 107 0.122
cell recognition GO:0008037 9 0.121
single organism membrane organization GO:0044802 268 0.120
cell proliferation involved in heart morphogenesis GO:0061323 1 0.120
positive regulation of neural precursor cell proliferation GO:2000179 2 0.117
positive chemotaxis GO:0050918 33 0.114
developmental maturation GO:0021700 28 0.114
blood coagulation GO:0007596 76 0.114
cytokinesis GO:0000910 96 0.113
nucleoside monophosphate catabolic process GO:0009125 159 0.112
neuron development GO:0048666 113 0.112
Mouse Rat Fly
regulation of proteolysis GO:0030162 293 0.111
regulation of cell migration GO:0030334 289 0.111
negative regulation of heart induction GO:1901320 1 0.110
neuron projection development GO:0031175 106 0.109
Mouse Rat Fly
leukocyte differentiation GO:0002521 98 0.108
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.107
negative regulation of interleukin 4 production GO:0032713 3 0.106
negative regulation of mitotic cell cycle GO:0045930 102 0.106
spindle assembly GO:0051225 29 0.106
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.104
metanephric nephron morphogenesis GO:0072273 7 0.104
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.103
dorsal ventral pattern formation GO:0009953 15 0.103
Mouse
regulation of cell fate specification GO:0042659 5 0.103
negative regulation of hexokinase activity GO:1903300 2 0.103
regulation of cardiac cell fate specification GO:2000043 1 0.103
negative regulation of multicellular organismal process GO:0051241 317 0.102
Mouse Worm Fly
regulation of ion transport GO:0043269 189 0.102
spindle localization GO:0051653 12 0.102
ribonucleoside monophosphate metabolic process GO:0009161 187 0.101

APC disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.343
neurodegenerative disease DOID:1289 102 0.343
nervous system disease DOID:863 431 0.343
reproductive organ cancer DOID:193 23 0.323
ovarian cancer DOID:2394 6 0.323
female reproductive organ cancer DOID:120 10 0.323
cancer DOID:162 167 0.323
disease of cellular proliferation DOID:14566 174 0.323
organ system cancer DOID:0050686 164 0.323
muscular disease DOID:0080000 114 0.110
musculoskeletal system disease DOID:17 223 0.110