Homo sapiens

20 known processes

ACTN3

actinin, alpha 3

(Aliases: MGC117005,MGC117002)

ACTN3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle system process GO:0003012 81 0.759
muscle contraction GO:0006936 73 0.755
skeletal muscle contraction GO:0003009 16 0.647
striated muscle contraction GO:0006941 52 0.626
actin filament based movement GO:0030048 17 0.449
atrial cardiac muscle tissue morphogenesis GO:0055009 1 0.407
muscle structure development GO:0061061 98 0.356
purine ribonucleotide catabolic process GO:0009154 404 0.349
system process GO:0003008 349 0.335
heart contraction GO:0060047 62 0.334
cardiac muscle contraction GO:0060048 34 0.302
musculoskeletal movement GO:0050881 17 0.289
circulatory system development GO:0072359 262 0.259
purine containing compound catabolic process GO:0072523 411 0.259
actin filament based process GO:0030029 224 0.247
glycosyl compound catabolic process GO:1901658 413 0.238
circulatory system process GO:0003013 113 0.236
heart process GO:0003015 62 0.227
regulation of muscle contraction GO:0006937 45 0.225
regulation of system process GO:0044057 101 0.224
actin mediated cell contraction GO:0070252 12 0.206
striated muscle tissue development GO:0014706 59 0.180
muscle tissue development GO:0060537 62 0.178
regulation of muscle system process GO:0090257 53 0.176
atrial cardiac muscle tissue development GO:0003228 1 0.169
multicellular organismal movement GO:0050879 17 0.167
ribonucleoside catabolic process GO:0042454 406 0.166
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.161
cardiovascular system development GO:0072358 262 0.153
cardiac ventricle development GO:0003231 23 0.153
nucleoside triphosphate metabolic process GO:0009141 422 0.152
atp catabolic process GO:0006200 157 0.151
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.149
nucleoside phosphate catabolic process GO:1901292 412 0.143
purine nucleoside catabolic process GO:0006152 398 0.138
heart development GO:0007507 95 0.136
cell development GO:0048468 328 0.133
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.133
voluntary skeletal muscle contraction GO:0003010 1 0.132
regulation of striated muscle contraction GO:0006942 37 0.132
purine nucleotide catabolic process GO:0006195 405 0.108
purine nucleoside monophosphate catabolic process GO:0009128 158 0.108
ribonucleoside monophosphate metabolic process GO:0009161 187 0.107
ribonucleoside triphosphate metabolic process GO:0009199 412 0.107
purine nucleoside triphosphate catabolic process GO:0009146 392 0.106
muscle organ morphogenesis GO:0048644 19 0.103
cardiac ventricle morphogenesis GO:0003208 20 0.103
nucleoside triphosphate catabolic process GO:0009143 394 0.102
anatomical structure formation involved in morphogenesis GO:0048646 284 0.100
purine ribonucleoside metabolic process GO:0046128 437 0.099
blood circulation GO:0008015 113 0.098
cardiac muscle tissue development GO:0048738 39 0.096
actin cytoskeleton organization GO:0030036 207 0.095
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.095
ribonucleotide catabolic process GO:0009261 405 0.092
nucleoside catabolic process GO:0009164 408 0.090
organ morphogenesis GO:0009887 147 0.089
cardiac muscle tissue morphogenesis GO:0055008 18 0.088
nucleotide catabolic process GO:0009166 408 0.086
ribonucleoside triphosphate catabolic process GO:0009203 391 0.085
nucleoside monophosphate metabolic process GO:0009123 191 0.085
nucleoside monophosphate catabolic process GO:0009125 159 0.084
atp metabolic process GO:0046034 176 0.083
purine ribonucleoside catabolic process GO:0046130 398 0.083
muscle organ development GO:0007517 56 0.081
muscle cell differentiation GO:0042692 63 0.079
purine nucleoside triphosphate metabolic process GO:0009144 412 0.078
cardiac muscle cell contraction GO:0086003 4 0.078
ribonucleoside monophosphate catabolic process GO:0009158 158 0.075
regulation of cardiac muscle contraction GO:0055117 33 0.072
cellular component assembly involved in morphogenesis GO:0010927 73 0.072
regulation of heart contraction GO:0008016 50 0.072
cellular component morphogenesis GO:0032989 314 0.070
striated muscle cell differentiation GO:0051146 43 0.065
regulation of blood circulation GO:1903522 59 0.065
heart morphogenesis GO:0003007 48 0.065
organophosphate catabolic process GO:0046434 430 0.062
tissue morphogenesis GO:0048729 96 0.062
purine nucleoside monophosphate metabolic process GO:0009126 186 0.062
muscle tissue morphogenesis GO:0060415 19 0.060
twitch skeletal muscle contraction GO:0014721 1 0.058
biological adhesion GO:0022610 331 0.058
cellular amino acid metabolic process GO:0006520 116 0.057
post embryonic development GO:0009791 2 0.055
locomotory behavior GO:0007626 1 0.055
regulation of cellular ketone metabolic process GO:0010565 50 0.053
cellular amine metabolic process GO:0044106 41 0.053
response to abiotic stimulus GO:0009628 336 0.052
organelle assembly GO:0070925 176 0.051
cell adhesion GO:0007155 325 0.051
chromatin organization GO:0006325 351 0.050
cellular ion homeostasis GO:0006873 168 0.049
cell morphogenesis GO:0000902 296 0.047
muscle cell development GO:0055001 29 0.047
ventricular cardiac muscle tissue development GO:0003229 14 0.047
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.046
multicellular organismal aging GO:0010259 3 0.045
positive regulation of cellular component organization GO:0051130 376 0.042
amine metabolic process GO:0009308 44 0.042
regulation of anatomical structure morphogenesis GO:0022603 286 0.042
mitotic cell cycle process GO:1903047 286 0.042
positive regulation of catabolic process GO:0009896 310 0.041
micturition GO:0060073 3 0.041
cell junction organization GO:0034330 79 0.041
mitotic cell cycle GO:0000278 326 0.041
regulation of cellular component movement GO:0051270 334 0.041
carbohydrate metabolic process GO:0005975 207 0.041
neuromuscular junction development GO:0007528 3 0.040
ion homeostasis GO:0050801 230 0.040
regulation of cellular amine metabolic process GO:0033238 11 0.040
negative regulation of multicellular organismal process GO:0051241 317 0.039
cell projection organization GO:0030030 252 0.039
cardiac chamber morphogenesis GO:0003206 26 0.038
muscle filament sliding GO:0030049 5 0.037
regulation of cell adhesion GO:0030155 166 0.037
response to decreased oxygen levels GO:0036293 96 0.037
regulation of protein localization GO:0032880 296 0.036
inorganic cation transmembrane transport GO:0098662 194 0.036
cation transmembrane transport GO:0098655 238 0.035
transmembrane transport GO:0055085 399 0.035
protein catabolic process GO:0030163 325 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
oogenesis GO:0048477 2 0.034
determination of adult lifespan GO:0008340 2 0.034
adult locomotory behavior GO:0008344 1 0.034
immune response GO:0006955 307 0.034
enzyme linked receptor protein signaling pathway GO:0007167 303 0.033
single organism carbohydrate metabolic process GO:0044723 193 0.032
regulation of nucleoside metabolic process GO:0009118 209 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
cellular chemical homeostasis GO:0055082 180 0.032
response to radiation GO:0009314 151 0.032
positive regulation of transport GO:0051050 336 0.031
cellular macromolecule catabolic process GO:0044265 380 0.031
cellular divalent inorganic cation homeostasis GO:0072503 128 0.031
inorganic ion transmembrane transport GO:0098660 231 0.031
segmentation GO:0035282 4 0.031
cardiac chamber development GO:0003205 30 0.031
negative regulation of phosphate metabolic process GO:0045936 267 0.031
regulation of purine nucleotide catabolic process GO:0033121 205 0.031
positive regulation of nucleotide metabolic process GO:0045981 230 0.031
regulation of nucleotide catabolic process GO:0030811 205 0.030
regulation of cell differentiation GO:0045595 393 0.030
rho protein signal transduction GO:0007266 26 0.030
skeletal muscle fiber development GO:0048741 12 0.030
regulation of nucleotide metabolic process GO:0006140 269 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
ion transmembrane transport GO:0034220 338 0.029
cell substrate adhesion GO:0031589 132 0.029
response to inorganic substance GO:0010035 127 0.029
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
skeletal muscle thin filament assembly GO:0030240 3 0.029
regulation of purine nucleotide metabolic process GO:1900542 264 0.029
cell cell junction organization GO:0045216 69 0.029
actomyosin structure organization GO:0031032 59 0.029
female gamete generation GO:0007292 2 0.028
chromatin modification GO:0016568 298 0.028
detection of stimulus GO:0051606 85 0.028
striated muscle cell development GO:0055002 27 0.028
negative regulation of protein metabolic process GO:0051248 391 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
regulation of ion transmembrane transporter activity GO:0032412 72 0.028
signal transduction by phosphorylation GO:0023014 297 0.027
oxidation reduction process GO:0055114 396 0.027
histone modification GO:0016570 251 0.027
positive regulation of nucleotide catabolic process GO:0030813 185 0.027
apoptotic signaling pathway GO:0097190 268 0.027
cellular ketone metabolic process GO:0042180 80 0.026
nervous system development GO:0007399 293 0.026
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.026
ras protein signal transduction GO:0007265 73 0.026
covalent chromatin modification GO:0016569 254 0.026
regulation of transmembrane transporter activity GO:0022898 74 0.025
organelle fission GO:0048285 149 0.025
regulation of transmembrane transport GO:0034762 139 0.025
regulation of actin filament based process GO:0032970 141 0.025
calcium ion homeostasis GO:0055074 122 0.025
mating GO:0007618 1 0.025
regulation of protein kinase activity GO:0045859 289 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
metal ion transport GO:0030001 272 0.025
positive regulation of nucleoside metabolic process GO:0045979 186 0.025
regulation of cell motility GO:2000145 299 0.025
vasculature development GO:0001944 181 0.025
protein oligomerization GO:0051259 173 0.024
chemical homeostasis GO:0048878 306 0.024
cellular protein complex assembly GO:0043623 188 0.024
positive regulation of cell differentiation GO:0045597 211 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.024
regulation of cellular response to stress GO:0080135 244 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
cellular protein catabolic process GO:0044257 261 0.024
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
protein localization to organelle GO:0033365 280 0.023
regulation of dna metabolic process GO:0051052 153 0.023
cellular response to abiotic stimulus GO:0071214 117 0.023
cation transport GO:0006812 331 0.023
regulation of kinase activity GO:0043549 314 0.023
regulation of transferase activity GO:0051338 355 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
response to hypoxia GO:0001666 96 0.023
multicellular organismal signaling GO:0035637 34 0.022
negative regulation of muscle contraction GO:0045932 3 0.022
action potential GO:0001508 34 0.022
regulation of cell cycle GO:0051726 393 0.022
response to oxidative stress GO:0006979 121 0.022
negative regulation of protein modification process GO:0031400 200 0.022
regulation of membrane potential GO:0042391 95 0.022
circadian behavior GO:0048512 2 0.022
cation homeostasis GO:0055080 189 0.022
tachykinin receptor signaling pathway GO:0007217 3 0.021
cytoplasmic transport GO:0016482 379 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
rhythmic behavior GO:0007622 2 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
response to oxygen levels GO:0070482 100 0.021
positive regulation of developmental process GO:0051094 314 0.021
response to activity GO:0014823 0 0.021
regulation of proteolysis GO:0030162 293 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
cell growth GO:0016049 160 0.020
myoblast fusion GO:0007520 1 0.020
syncytium formation by plasma membrane fusion GO:0000768 2 0.020
growth GO:0040007 202 0.020
nuclear division GO:0000280 128 0.020
anterior posterior axis specification GO:0009948 2 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
cell cycle phase transition GO:0044770 173 0.020
actin filament organization GO:0007015 128 0.020
cellular cation homeostasis GO:0030003 163 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
response to light stimulus GO:0009416 87 0.019
blastoderm segmentation GO:0007350 2 0.019
positive regulation of organelle organization GO:0010638 195 0.019
microtubule based process GO:0007017 210 0.019
regulation of mapk cascade GO:0043408 262 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
mitotic nuclear division GO:0007067 119 0.019
single organism membrane organization GO:0044802 268 0.019
tissue migration GO:0090130 119 0.019
epithelium development GO:0060429 227 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
regulation of response to external stimulus GO:0032101 222 0.019
regeneration GO:0031099 4 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
negative regulation of transport GO:0051051 176 0.019
regulation of atpase activity GO:0043462 25 0.019
membrane organization GO:0061024 292 0.018
cell junction assembly GO:0034329 67 0.018
cytokine production GO:0001816 247 0.018
regulation of ion transport GO:0043269 189 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
positive regulation of aldosterone metabolic process GO:0032346 2 0.018
mapk cascade GO:0000165 288 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
dna repair GO:0006281 198 0.018
regulation of intracellular transport GO:0032386 195 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
av node cell to bundle of his cell communication GO:0086067 4 0.018
regulation of cell migration GO:0030334 289 0.018
pulmonary valve formation GO:0003193 1 0.018
regulation of atp catabolic process GO:1903289 25 0.018
regulation of skeletal muscle contraction GO:0014819 3 0.018
cellular response to growth factor stimulus GO:0071363 197 0.017
modification dependent protein catabolic process GO:0019941 209 0.017
generation of neurons GO:0048699 152 0.017
hindbrain development GO:0030902 3 0.017
sleep GO:0030431 2 0.017
modification dependent macromolecule catabolic process GO:0043632 212 0.017
intrinsic apoptotic signaling pathway GO:0097193 127 0.017
memory GO:0007613 3 0.017
dephosphorylation GO:0016311 209 0.017
intracellular protein transport GO:0006886 270 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
spermatid differentiation GO:0048515 4 0.017
protein processing GO:0016485 226 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
regulation of transporter activity GO:0032409 82 0.017
protein maturation GO:0051604 233 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
regulation of ion transmembrane transport GO:0034765 132 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
maintenance of location GO:0051235 112 0.016
regulation of atp metabolic process GO:1903578 29 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
behavior GO:0007610 112 0.016
cell projection assembly GO:0030031 126 0.016
negative regulation of cell cycle GO:0045786 193 0.016
regulation of cell cycle process GO:0010564 266 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
epithelium migration GO:0090132 119 0.016
monovalent inorganic cation transport GO:0015672 128 0.016
positive regulation of hormone biosynthetic process GO:0046886 4 0.016
single organism cellular localization GO:1902580 332 0.016
rna processing GO:0006396 255 0.016
regulation of cytokine production GO:0001817 232 0.016
postsynaptic membrane organization GO:0001941 2 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.016
regulation of protein transport GO:0051223 213 0.016
synaptic transmission cholinergic GO:0007271 2 0.016
skeletal muscle tissue development GO:0007519 24 0.016
positive regulation of cell death GO:0010942 263 0.016
spermatid development GO:0007286 4 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
single organismal cell cell adhesion GO:0016337 148 0.016
synaptic transmission involved in micturition GO:0060084 2 0.016
protein targeting GO:0006605 187 0.016
negative regulation of striated muscle contraction GO:0045988 2 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.015
tissue regeneration GO:0042246 3 0.015
compound eye development GO:0048749 1 0.015
cellular metal ion homeostasis GO:0006875 146 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
regulation of protein maturation GO:1903317 150 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
response to growth factor GO:0070848 205 0.015
regulation of protein catabolic process GO:0042176 155 0.015
response to fungus GO:0009620 4 0.015
epidermis morphogenesis GO:0048730 3 0.015
regulation of cell growth GO:0001558 135 0.015
response to oxygen containing compound GO:1901700 369 0.015
glycoprotein metabolic process GO:0009100 110 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
regulation of cell projection organization GO:0031344 107 0.015
regulation of feeding behavior GO:0060259 3 0.015
negative regulation of catabolic process GO:0009895 104 0.015
carbohydrate catabolic process GO:0016052 36 0.015
metencephalon development GO:0022037 2 0.014
somatic muscle development GO:0007525 1 0.014
nitrogen compound transport GO:0071705 191 0.014
anatomical structure homeostasis GO:0060249 100 0.014
cellular homeostasis GO:0019725 196 0.014
nuclear transport GO:0051169 179 0.014
positive regulation of kinase activity GO:0033674 204 0.014
neurological system process GO:0050877 163 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.014
negative regulation of growth GO:0045926 97 0.014
wound healing GO:0042060 115 0.014
sensory perception GO:0007600 103 0.014
cerebellum development GO:0021549 2 0.014
alcohol metabolic process GO:0006066 114 0.014
defense response GO:0006952 315 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
negative regulation of transferase activity GO:0051348 124 0.014
potassium ion transport GO:0006813 62 0.014
regulation of carbohydrate metabolic process GO:0006109 54 0.014
response to cytokine GO:0034097 232 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.014
oocyte development GO:0048599 1 0.014
protein ubiquitination GO:0016567 314 0.014
negative regulation of developmental process GO:0051093 247 0.014
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
negative regulation of cell growth GO:0030308 83 0.014
protein tetramerization GO:0051262 47 0.014
glycoprotein biosynthetic process GO:0009101 91 0.013
mitochondrion organization GO:0007005 156 0.013
cellular potassium ion transport GO:0071804 60 0.013
gtp catabolic process GO:0006184 237 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
regulation of protein processing GO:0070613 150 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
positive regulation of proteolysis GO:0045862 142 0.013
cell part morphogenesis GO:0032990 137 0.013
negative regulation of cell death GO:0060548 345 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
muscle fiber development GO:0048747 16 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
tripartite regional subdivision GO:0007351 2 0.013
potassium ion transmembrane transport GO:0071805 60 0.013
innate immune response GO:0045087 178 0.013
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.013
gtp metabolic process GO:0046039 239 0.013
oocyte differentiation GO:0009994 2 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
neurogenesis GO:0022008 169 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
regulation of body fluid levels GO:0050878 99 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.013
positive regulation of protein transport GO:0051222 135 0.013
myosin filament assembly GO:0031034 2 0.013
positive regulation of immune system process GO:0002684 283 0.013
neuroblast proliferation GO:0007405 4 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
hexose metabolic process GO:0019318 55 0.013
negative regulation of organelle organization GO:0010639 126 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of immune response GO:0050776 201 0.013
blood vessel development GO:0001568 172 0.012
regulation of peptidase activity GO:0052547 180 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
myosin filament organization GO:0031033 2 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
protein homooligomerization GO:0051260 100 0.012
response to organic cyclic compound GO:0014070 204 0.012
head development GO:0060322 108 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
small molecule biosynthetic process GO:0044283 157 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
negative regulation of protein kinase activity GO:0006469 98 0.012
regulation of growth GO:0040008 165 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
cell cell signaling GO:0007267 155 0.012
cellular component disassembly GO:0022411 92 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
regulation of gtpase activity GO:0043087 180 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
sensory perception of light stimulus GO:0050953 35 0.012
cell substrate adherens junction assembly GO:0007045 30 0.012
negative regulation of kinase activity GO:0033673 106 0.012
epithelial cell differentiation GO:0030855 141 0.012
negative regulation of proteolysis GO:0045861 132 0.012
protein localization to nucleus GO:0034504 136 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
neuron projection development GO:0031175 106 0.012
response to external biotic stimulus GO:0043207 261 0.012
thymus development GO:0048538 3 0.012
taxis GO:0042330 157 0.012
neurotransmitter secretion GO:0007269 4 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
membrane repolarization GO:0086009 23 0.012
regulation of cell development GO:0060284 161 0.012
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.012
negative regulation of protein processing GO:0010955 142 0.012
sex determination GO:0007530 3 0.011
actin myosin filament sliding GO:0033275 6 0.011
ameboidal type cell migration GO:0001667 135 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
endocytosis GO:0006897 159 0.011
protein localization to membrane GO:0072657 160 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.011
positive regulation of ion transport GO:0043270 87 0.011
meiosis i GO:0007127 4 0.011
lipid metabolic process GO:0006629 381 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.011
sensory organ development GO:0007423 52 0.011
regulation of protein targeting GO:1903533 91 0.011
endomembrane system organization GO:0010256 196 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
cardiac conduction GO:0061337 23 0.011
response to organonitrogen compound GO:0010243 156 0.011
single organism cell adhesion GO:0098602 179 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011

ACTN3 disease predictions

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 114 0.784
musculoskeletal system disease DOID:17 223 0.784
muscle tissue disease DOID:66 113 0.716
myopathy DOID:423 104 0.165
heart disease DOID:114 68 0.165
cardiomyopathy DOID:0050700 50 0.165
intrinsic cardiomyopathy DOID:0060036 50 0.165
cardiovascular system disease DOID:1287 106 0.165
disease of metabolism DOID:0014667 295 0.054
distal arthrogryposis DOID:0050646 9 0.048
muscular dystrophy DOID:9884 51 0.042
sensory system disease DOID:0050155 203 0.029
nervous system disease DOID:863 431 0.029
central nervous system disease DOID:331 186 0.021
inherited metabolic disorder DOID:655 242 0.021
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
disease of cellular proliferation DOID:14566 174 0.014
auditory system disease DOID:2742 53 0.013
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.013
neurodegenerative disease DOID:1289 102 0.013
retinal disease DOID:5679 118 0.012
acquired metabolic disease DOID:0060158 58 0.012
immune system disease DOID:2914 155 0.012
hypertrophic cardiomyopathy DOID:11984 21 0.011