Homo sapiens

30 known processes

ACTN1

actinin, alpha 1

(Aliases: FLJ40884,FLJ54432)

ACTN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 224 0.999
Mouse Fly
actin cytoskeleton organization GO:0030036 207 0.996
Mouse Fly
cellular component assembly involved in morphogenesis GO:0010927 73 0.995
Fly
muscle cell development GO:0055001 29 0.994
Fly
cellular component morphogenesis GO:0032989 314 0.989
Fly
ameboidal type cell migration GO:0001667 135 0.982
anatomical structure formation involved in morphogenesis GO:0048646 284 0.979
Fly
organelle assembly GO:0070925 176 0.959
Fly
cell development GO:0048468 328 0.955
Fly
striated muscle cell differentiation GO:0051146 43 0.945
Fly
actin filament organization GO:0007015 128 0.938
Mouse
muscle system process GO:0003012 81 0.921
actomyosin structure organization GO:0031032 59 0.912
Fly
cardiac muscle tissue development GO:0048738 39 0.911
sarcomere organization GO:0045214 8 0.892
Fly
cell morphogenesis GO:0000902 296 0.877
muscle structure development GO:0061061 98 0.875
Fly
muscle cell differentiation GO:0042692 63 0.855
Fly
regulation of cytoskeleton organization GO:0051493 177 0.829
coagulation GO:0050817 78 0.828
biological adhesion GO:0022610 331 0.817
striated muscle cell development GO:0055002 27 0.813
Fly
actin filament polymerization GO:0030041 45 0.765
actin polymerization or depolymerization GO:0008154 56 0.755
tube development GO:0035295 125 0.749
skeletal muscle thin filament assembly GO:0030240 3 0.735
cellular macromolecular complex assembly GO:0034622 324 0.725
regulation of actin filament polymerization GO:0030833 50 0.722
cell adhesion GO:0007155 325 0.674
circulatory system development GO:0072359 262 0.660
positive regulation of cellular component organization GO:0051130 376 0.649
regulation of actin cytoskeleton organization GO:0032956 116 0.615
female gamete generation GO:0007292 2 0.601
cell morphogenesis involved in differentiation GO:0000904 144 0.557
mating GO:0007618 1 0.531
cellular amine metabolic process GO:0044106 41 0.530
regulation of actin filament depolymerization GO:0030834 10 0.509
regulation of actin filament based process GO:0032970 141 0.508
negative regulation of hippo signaling GO:0035331 6 0.504
regulation of cell motility GO:2000145 299 0.490
locomotory behavior GO:0007626 1 0.489
Fly
single organismal cell cell adhesion GO:0016337 148 0.483
positive regulation of transport GO:0051050 336 0.483
Human
system process GO:0003008 349 0.463
regulation of protein polymerization GO:0032271 63 0.461
myofibril assembly GO:0030239 10 0.456
Fly
atp catabolic process GO:0006200 157 0.435
platelet aggregation GO:0070527 32 0.420
anterior posterior axis specification GO:0009948 2 0.417
regulation of cell morphogenesis GO:0022604 153 0.413
response to hypoxia GO:0001666 96 0.407
regulation of actin polymerization or depolymerization GO:0008064 56 0.395
negative regulation of cellular component movement GO:0051271 106 0.394
response to growth factor GO:0070848 205 0.386
wound healing GO:0042060 115 0.383
oogenesis GO:0048477 2 0.368
response to oxygen levels GO:0070482 100 0.364
regulation of cellular component biogenesis GO:0044087 281 0.362
actin filament bundle organization GO:0061572 54 0.361
Mouse
barbed end actin filament capping GO:0051016 3 0.346
response to abiotic stimulus GO:0009628 336 0.335
tissue morphogenesis GO:0048729 96 0.313
response to decreased oxygen levels GO:0036293 96 0.309
neuron projection regeneration GO:0031102 1 0.309
nerve development GO:0021675 4 0.306
regulation of cellular ketone metabolic process GO:0010565 50 0.306
maintenance of location in cell GO:0051651 62 0.304
cellular protein complex assembly GO:0043623 188 0.295
regulation of epithelial cell migration GO:0010632 93 0.293
nervous system development GO:0007399 293 0.291
blood coagulation GO:0007596 76 0.288
regulation of body fluid levels GO:0050878 99 0.283
striated muscle tissue development GO:0014706 59 0.279
cell part morphogenesis GO:0032990 137 0.278
regulation of actin filament length GO:0030832 56 0.277
hippo signaling GO:0035329 20 0.260
regulation of anatomical structure morphogenesis GO:0022603 286 0.259
transmission of nerve impulse GO:0019226 11 0.255
cell activation GO:0001775 213 0.249
integrin mediated signaling pathway GO:0007229 32 0.248
regulation of membrane potential GO:0042391 95 0.245
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.242
regulation of cellular amine metabolic process GO:0033238 11 0.239
cell projection assembly GO:0030031 126 0.238
Human
neurogenesis GO:0022008 169 0.237
ribonucleoside monophosphate metabolic process GO:0009161 187 0.236
positive regulation of cell motility GO:2000147 177 0.232
endothelial cell migration GO:0043542 86 0.230
regulation of metal ion transport GO:0010959 120 0.227
Human
regulation of locomotion GO:0040012 329 0.219
regulation of actin filament bundle assembly GO:0032231 36 0.218
amine metabolic process GO:0009308 44 0.215
integrin activation GO:0033622 8 0.214
tube morphogenesis GO:0035239 95 0.213
nucleoside monophosphate catabolic process GO:0009125 159 0.210
nucleoside catabolic process GO:0009164 408 0.209
motor neuron axon guidance GO:0008045 2 0.208
cell matrix adhesion GO:0007160 85 0.202
negative regulation of protein complex disassembly GO:0043242 20 0.199
negative regulation of cell motility GO:2000146 104 0.199
blood vessel endothelial cell migration GO:0043534 42 0.198
anterior posterior axis specification embryo GO:0008595 2 0.198
nucleoside monophosphate metabolic process GO:0009123 191 0.197
embryo development GO:0009790 123 0.195
Worm
morphogenesis of embryonic epithelium GO:0016331 4 0.192
maintenance of location GO:0051235 112 0.190
regulation of protein import into nucleus GO:0042306 78 0.189
negative regulation of apoptotic process GO:0043066 316 0.189
inorganic ion transmembrane transport GO:0098660 231 0.187
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.187
adherens junction organization GO:0034332 36 0.185
regulation of cellular component movement GO:0051270 334 0.183
positive regulation of intracellular protein transport GO:0090316 76 0.183
regulation of protein complex assembly GO:0043254 147 0.180
tripartite regional subdivision GO:0007351 2 0.180
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.177
positive regulation of cytoskeleton organization GO:0051495 83 0.174
stress fiber assembly GO:0043149 40 0.173
regulation of protein localization GO:0032880 296 0.172
Human
protein import GO:0017038 130 0.170
cell projection morphogenesis GO:0048858 129 0.170
positive regulation of cellular component movement GO:0051272 181 0.169
Human
adult locomotory behavior GO:0008344 1 0.167
Fly
cardiac muscle cell differentiation GO:0055007 15 0.166
regulation of cellular component size GO:0032535 82 0.162
cardiac muscle contraction GO:0060048 34 0.159
homotypic cell cell adhesion GO:0034109 47 0.157
protein localization to membrane GO:0072657 160 0.155
purine nucleoside monophosphate metabolic process GO:0009126 186 0.155
cellular potassium ion transport GO:0071804 60 0.153
Human
muscle contraction GO:0006936 73 0.153
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.152
cation transport GO:0006812 331 0.150
Human
myosin filament assembly GO:0031034 2 0.148
cellular protein complex disassembly GO:0043624 36 0.148
single organism cell adhesion GO:0098602 179 0.147
gene silencing by mirna GO:0035195 23 0.146
positive regulation of cell migration GO:0030335 172 0.145
regulation of protein localization to nucleus GO:1900180 85 0.140
protein targeting GO:0006605 187 0.139
ion transmembrane transport GO:0034220 338 0.138
Human
nadph oxidation GO:0070995 3 0.136
maintenance of protein location GO:0045185 57 0.136
cell substrate adherens junction assembly GO:0007045 30 0.135
regulation of cellular amino acid metabolic process GO:0006521 6 0.134
digestive system development GO:0055123 75 0.134
regulation of cell development GO:0060284 161 0.134
protein catabolic process GO:0030163 325 0.134
Worm
response to oxidative stress GO:0006979 121 0.133
purine nucleotide catabolic process GO:0006195 405 0.130
hemostasis GO:0007599 76 0.129
transmembrane transport GO:0055085 399 0.128
Human
pattern specification process GO:0007389 43 0.127
regulation of nucleotide metabolic process GO:0006140 269 0.126
protein depolymerization GO:0051261 30 0.125
negative regulation of actin filament depolymerization GO:0030835 5 0.124
regulation of protein targeting GO:1903533 91 0.122
striated muscle myosin thick filament assembly GO:0071688 2 0.121
post embryonic development GO:0009791 2 0.120
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.119
response to wounding GO:0009611 168 0.117
cell junction organization GO:0034330 79 0.116
muscle organ morphogenesis GO:0048644 19 0.116
cellular response to decreased oxygen levels GO:0036294 51 0.116
single organism cellular localization GO:1902580 332 0.116
negative regulation of organelle organization GO:0010639 126 0.115
ribonucleoprotein complex biogenesis GO:0022613 116 0.114
establishment of protein localization to organelle GO:0072594 172 0.114
behavior GO:0007610 112 0.114
Fly
regulation of cell migration GO:0030334 289 0.113
epithelial cell development GO:0002064 34 0.108
cytoplasmic mrna processing body assembly GO:0033962 10 0.107
cellular response to oxidative stress GO:0034599 85 0.107
multicellular organismal aging GO:0010259 3 0.105
maintenance of protein location in cell GO:0032507 56 0.104
negative regulation of cell migration GO:0030336 102 0.104
peptidyl serine modification GO:0018209 106 0.103
organ morphogenesis GO:0009887 147 0.102
regulation of cell shape GO:0008360 48 0.101
regulation of anatomical structure size GO:0090066 101 0.101
platelet activation GO:0030168 44 0.100
adherens junction assembly GO:0034333 34 0.099
endocytosis GO:0006897 159 0.097
actin filament capping GO:0051693 4 0.096
epithelial cell differentiation GO:0030855 141 0.095
actin filament bundle assembly GO:0051017 54 0.094
Mouse
oocyte differentiation GO:0009994 2 0.093
embryonic epithelial tube formation GO:0001838 4 0.092
regulation of vesicle mediated transport GO:0060627 130 0.092
protein polymerization GO:0051258 71 0.092
ribonucleoprotein complex subunit organization GO:0071826 81 0.092
specification of axis polarity GO:0065001 1 0.090
protein import into nucleus GO:0006606 104 0.090
potassium ion transmembrane transport GO:0071805 60 0.090
Human
apical junction assembly GO:0043297 19 0.088
cardiac ventricle development GO:0003231 23 0.087
taxis GO:0042330 157 0.086
vocalization behavior GO:0071625 11 0.086
protein complex disassembly GO:0043241 52 0.085
regulation of transcription factor import into nucleus GO:0042990 39 0.084
digestive tract development GO:0048565 75 0.083
positive regulation of organelle organization GO:0010638 195 0.083
ribonucleoside monophosphate catabolic process GO:0009158 158 0.081
prostate gland stromal morphogenesis GO:0060741 1 0.080
blood vessel morphogenesis GO:0048514 162 0.080
somitogenesis GO:0001756 2 0.078
ribonucleoprotein complex assembly GO:0022618 78 0.078
atp metabolic process GO:0046034 176 0.077
positive regulation of protein import into nucleus GO:0042307 46 0.077
negative regulation of cytoskeleton organization GO:0051494 45 0.077
blood vessel development GO:0001568 172 0.076
skeletal myofibril assembly GO:0014866 3 0.076
positive regulation of protein localization to nucleus GO:1900182 48 0.075
purine nucleoside monophosphate catabolic process GO:0009128 158 0.075
segmentation GO:0035282 4 0.074
peptidyl threonine modification GO:0018210 45 0.074
glomerular mesangial cell differentiation GO:0072008 2 0.073
plasma membrane organization GO:0007009 115 0.072
epithelial tube morphogenesis GO:0060562 38 0.071
osteoblast differentiation GO:0001649 92 0.071
negative regulation of apoptotic signaling pathway GO:2001234 97 0.070
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.069
cytoplasmic sequestering of protein GO:0051220 12 0.069
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.068
regulation of protein localization to cell surface GO:2000008 15 0.067
Human
cellular response to oxygen levels GO:0071453 55 0.067
microtubule cytoskeleton organization GO:0000226 176 0.067
chronological cell aging GO:0001300 2 0.065
vesicle mediated transport GO:0016192 371 0.064
mitotic cell cycle process GO:1903047 286 0.064
Worm
cellular ketone metabolic process GO:0042180 80 0.064
neuroblast proliferation GO:0007405 4 0.064
regulation of stress fiber assembly GO:0051492 32 0.062
elastic fiber assembly GO:0048251 3 0.062
ventricular cardiac muscle tissue development GO:0003229 14 0.061
muscle tissue morphogenesis GO:0060415 19 0.061
epithelial cell cell adhesion GO:0090136 7 0.061
pharynx development GO:0060465 1 0.061
positive regulation of cellular amine metabolic process GO:0033240 7 0.059
purine nucleoside triphosphate metabolic process GO:0009144 412 0.059
lens morphogenesis in camera type eye GO:0002089 2 0.059
heart morphogenesis GO:0003007 48 0.058
memory GO:0007613 3 0.057
myosin filament organization GO:0031033 2 0.057
cell junction assembly GO:0034329 67 0.057
positive regulation of actin filament bundle assembly GO:0032233 25 0.057
microtubule based process GO:0007017 210 0.057
growth GO:0040007 202 0.057
positive regulation of protein complex assembly GO:0031334 86 0.057
actin crosslink formation GO:0051764 1 0.056
neural tube formation GO:0001841 3 0.056
regulation of purine nucleotide metabolic process GO:1900542 264 0.056
cellular amino acid metabolic process GO:0006520 116 0.056
regulation of nucleoside metabolic process GO:0009118 209 0.056
nuclear transport GO:0051169 179 0.055
cellular component disassembly GO:0022411 92 0.055
regulation of cell matrix adhesion GO:0001952 42 0.055
purine ribonucleoside catabolic process GO:0046130 398 0.055
regulation of cardiac muscle cell apoptotic process GO:0010665 3 0.054
positive regulation of potassium ion transport GO:0043268 15 0.054
Human
associative learning GO:0008306 1 0.054
cell division GO:0051301 168 0.054
positive regulation of axon extension GO:0045773 4 0.054
axonogenesis GO:0007409 31 0.054
nucleotide catabolic process GO:0009166 408 0.053
negative regulation of multicellular organismal process GO:0051241 317 0.053
striated muscle contraction GO:0006941 52 0.053
protein oligomerization GO:0051259 173 0.053
Human
apoptotic signaling pathway GO:0097190 268 0.053
muscle tissue development GO:0060537 62 0.053
intracellular protein transport GO:0006886 270 0.052
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.052
cellular response to oxygen containing compound GO:1901701 276 0.052
response to oxygen containing compound GO:1901700 369 0.051
regulation of cell maturation GO:1903429 3 0.050
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.050
regulation of cytoplasmic transport GO:1903649 149 0.050
positive regulation of transcription factor import into nucleus GO:0042993 25 0.050
regulation of muscle hypertrophy GO:0014743 10 0.049
salivary gland morphogenesis GO:0007435 4 0.049
multicellular organismal signaling GO:0035637 34 0.048
modification dependent protein catabolic process GO:0019941 209 0.048
protein homooligomerization GO:0051260 100 0.048
Human
reproductive process GO:0022414 106 0.047
cytokinesis GO:0000910 96 0.047
peptidyl tyrosine phosphorylation GO:0018108 170 0.047
positive regulation of stress fiber assembly GO:0051496 22 0.047
negative regulation of protein transport GO:0051224 75 0.047
cardiovascular system development GO:0072358 262 0.047
regulation of establishment of protein localization GO:0070201 242 0.046
muscle organ development GO:0007517 56 0.046
positive regulation of cellular component biogenesis GO:0044089 158 0.046
regulation of collagen catabolic process GO:0010710 3 0.045
metal ion transport GO:0030001 272 0.045
Human
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.044
negative regulation of transport GO:0051051 176 0.044
Human
regulation of atpase activity GO:0043462 25 0.044
developmental cell growth GO:0048588 18 0.044
negative regulation of cellular amine metabolic process GO:0033239 3 0.044
cell migration involved in gastrulation GO:0042074 1 0.044
myoblast fusion GO:0007520 1 0.044
negative regulation of developmental process GO:0051093 247 0.043
morphogenesis of an epithelium GO:0002009 60 0.043
negative regulation of intracellular signal transduction GO:1902532 183 0.043
negative regulation of potassium ion transmembrane transport GO:1901380 5 0.043
Human
regulation of cell adhesion GO:0030155 166 0.043
regulation of glial cell differentiation GO:0045685 3 0.043
cellular response to endogenous stimulus GO:0071495 336 0.043
cytoskeletal anchoring at plasma membrane GO:0007016 1 0.042
i kappab kinase nf kappab signaling GO:0007249 166 0.042
positive regulation of protein transport GO:0051222 135 0.042
positive regulation of ion transport GO:0043270 87 0.042
Human
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.042
nucleoside triphosphate catabolic process GO:0009143 394 0.042
positive regulation of transporter activity GO:0032411 32 0.041
Human
actin filament depolymerization GO:0030042 12 0.041
cardiac muscle cell development GO:0055013 5 0.040
cation transmembrane transport GO:0098655 238 0.040
Human
cilium morphogenesis GO:0060271 75 0.040
adenylate cyclase inhibiting dopamine receptor signaling pathway GO:0007195 4 0.039
negative regulation of locomotion GO:0040013 118 0.039
cranial nerve development GO:0021545 4 0.039
angiogenesis GO:0001525 147 0.038
single organism nuclear import GO:1902593 104 0.038
negative regulation of protein complex assembly GO:0031333 43 0.038
positive regulation of cytoplasmic transport GO:1903651 82 0.038
nucleocytoplasmic transport GO:0006913 176 0.038
regulation of oocyte development GO:0060281 1 0.038
cell substrate adhesion GO:0031589 132 0.038
regulation of protein transport GO:0051223 213 0.038
action potential GO:0001508 34 0.038
tube closure GO:0060606 3 0.038
positive regulation of intracellular transport GO:0032388 104 0.037
single organism membrane organization GO:0044802 268 0.037
negative regulation of cell death GO:0060548 345 0.036
negative regulation of protein modification process GO:0031400 200 0.035
cytoplasmic transport GO:0016482 379 0.035
regulation of potassium ion transport GO:0043266 24 0.035
Human
negative regulation of plasminogen activation GO:0010757 4 0.035
regulation of extent of cell growth GO:0061387 9 0.035
heart process GO:0003015 62 0.034
generation of neurons GO:0048699 152 0.034
regulation of atp metabolic process GO:1903578 29 0.034
regulation of cardiac muscle cell membrane potential GO:0086036 1 0.034
protein localization to organelle GO:0033365 280 0.034
determination of adult lifespan GO:0008340 2 0.034
regulation of potassium ion transmembrane transport GO:1901379 20 0.034
Human
transcription factor import into nucleus GO:0042991 40 0.034
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.033
cellular response to hypoxia GO:0071456 51 0.033
cell chemotaxis GO:0060326 112 0.033
adult behavior GO:0030534 18 0.033
Fly
regulation of response to wounding GO:1903034 101 0.033
cell projection organization GO:0030030 252 0.033
Human
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.033
Human
negative regulation of ion transmembrane transport GO:0034766 26 0.032
Human
regulation of cell projection organization GO:0031344 107 0.032
membrane protein ectodomain proteolysis GO:0006509 33 0.032
blastoderm segmentation GO:0007350 2 0.032
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.032
purine nucleoside catabolic process GO:0006152 398 0.032
platelet formation GO:0030220 4 0.032
purine ribonucleoside metabolic process GO:0046128 437 0.032
fusion of sperm to egg plasma membrane GO:0007342 2 0.031
positive regulation of synaptic transmission GO:0050806 4 0.031
negative regulation of transporter activity GO:0032410 25 0.031
Human
cuticle development GO:0042335 1 0.031
positive regulation of cell differentiation GO:0045597 211 0.030
cardiocyte differentiation GO:0035051 23 0.030
neuron development GO:0048666 113 0.030
basement membrane organization GO:0071711 3 0.030
regulation of transmembrane transport GO:0034762 139 0.030
Human
mitotic nuclear division GO:0007067 119 0.030
Worm
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.030
central nervous system development GO:0007417 123 0.029
cellular response to reactive oxygen species GO:0034614 50 0.029
purine containing compound catabolic process GO:0072523 411 0.029
positive regulation of cell development GO:0010720 92 0.029
regulation of transporter activity GO:0032409 82 0.028
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
response to transforming growth factor beta GO:0071559 94 0.028
spermatid development GO:0007286 4 0.028
uterus morphogenesis GO:0061038 2 0.028
skin development GO:0043588 76 0.028
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.027
peripheral nervous system development GO:0007422 2 0.027
morphogenesis of a polarized epithelium GO:0001738 3 0.027
negative regulation of cellular component organization GO:0051129 235 0.027
regulation of intracellular transport GO:0032386 195 0.027
oocyte development GO:0048599 1 0.027
cell cell junction assembly GO:0007043 25 0.027
proteasomal protein catabolic process GO:0010498 176 0.027
regulation of nervous system development GO:0051960 88 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
membrane organization GO:0061024 292 0.026
macromolecular complex disassembly GO:0032984 60 0.026
regulation of protein kinase activity GO:0045859 289 0.026
leukotriene production involved in inflammatory response GO:0002540 1 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
midgut development GO:0007494 1 0.026
negative regulation of transmembrane transport GO:0034763 29 0.026
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.025
regulation of protein depolymerization GO:1901879 22 0.025
regulation of atp catabolic process GO:1903289 25 0.025
negative regulation of protein localization to nucleus GO:1900181 34 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
neuron remodeling GO:0016322 2 0.025
regionalization GO:0003002 29 0.025
branching morphogenesis of an epithelial tube GO:0048754 19 0.025
neuronal action potential GO:0019228 9 0.025
lipid localization GO:0010876 106 0.024
epithelial cell migration GO:0010631 119 0.024
positive regulation of catabolic process GO:0009896 310 0.024
chemotaxis GO:0006935 157 0.024
neurotransmitter secretion GO:0007269 4 0.024
regulation of meiotic cell cycle GO:0051445 4 0.024
neural tube closure GO:0001843 3 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.023
negative regulation of neural precursor cell proliferation GO:2000178 1 0.023
lens development in camera type eye GO:0002088 2 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.023
regulation of cell cycle GO:0051726 393 0.023
reproduction GO:0000003 63 0.023
organophosphate catabolic process GO:0046434 430 0.023
divalent metal ion transport GO:0070838 152 0.023
embryonic morphogenesis GO:0048598 85 0.023
brain development GO:0007420 97 0.023
nucleus localization GO:0051647 1 0.023
multicellular organism reproduction GO:0032504 42 0.023
cardiac muscle tissue morphogenesis GO:0055008 18 0.023
apoptotic mitochondrial changes GO:0008637 57 0.023
positive regulation of actin filament polymerization GO:0030838 38 0.023
glial cell migration GO:0008347 4 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.022
actin cytoskeleton reorganization GO:0031532 37 0.022
Fly
early endosome to late endosome transport GO:0045022 21 0.022
mitochondrion organization GO:0007005 156 0.022
regulation of neuroblast proliferation GO:1902692 3 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
neural tube development GO:0021915 9 0.022
optic nerve development GO:0021554 2 0.022
cytoplasmic sequestering of transcription factor GO:0042994 9 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
regulation of vasculature development GO:1901342 97 0.022
rho protein signal transduction GO:0007266 26 0.022
positive regulation of developmental process GO:0051094 314 0.022
nuclear migration GO:0007097 1 0.022
positive regulation of locomotion GO:0040017 186 0.022
response to axon injury GO:0048678 1 0.022
positive regulation of nf kappab import into nucleus GO:0042346 13 0.021
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.021
Human
spermatid differentiation GO:0048515 4 0.021
vasculature development GO:0001944 181 0.021
negative regulation of protein phosphorylation GO:0001933 140 0.021
cerebral cortex cell migration GO:0021795 3 0.021
response to metal ion GO:0010038 84 0.020
cardiac cell development GO:0055006 5 0.020
negative regulation of transcription factor import into nucleus GO:0042992 17 0.020
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.020
renal system development GO:0072001 63 0.020
cardiac myofibril assembly GO:0055003 3 0.020
syncytium formation by plasma membrane fusion GO:0000768 2 0.020
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.020
epithelium development GO:0060429 227 0.020
regulation of protein binding GO:0043393 66 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
primary neural tube formation GO:0014020 3 0.020
sensory perception GO:0007600 103 0.020
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.020

ACTN1 disease predictions

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 36 0.844
Human
urinary system disease DOID:18 40 0.844
Human
cardiovascular system disease DOID:1287 106 0.371
auditory system disease DOID:2742 53 0.190
sensory system disease DOID:0050155 203 0.190
nervous system disease DOID:863 431 0.190
myopathy DOID:423 104 0.142
muscular disease DOID:0080000 114 0.142
heart disease DOID:114 68 0.142
cardiomyopathy DOID:0050700 50 0.142
musculoskeletal system disease DOID:17 223 0.142
muscle tissue disease DOID:66 113 0.142
dilated cardiomyopathy DOID:12930 32 0.097
intrinsic cardiomyopathy DOID:0060036 50 0.097
central nervous system disease DOID:331 186 0.085
neurodegenerative disease DOID:1289 102 0.079
autosomal dominant nonsyndromic deafness DOID:0050564 23 0.033
nonsyndromic deafness DOID:0050563 50 0.033
bone disease DOID:0080001 88 0.032
connective tissue disease DOID:65 109 0.032
muscular dystrophy DOID:9884 51 0.029
cancer DOID:162 167 0.026
disease of cellular proliferation DOID:14566 174 0.026