Homo sapiens

58 known processes

PTPRO

protein tyrosine phosphatase, receptor type, O

(Aliases: PTP-oc,PTPU2,GLEPP1,PTP-U2)

PTPRO biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pyrimidine containing compound catabolic process GO:0072529 13 0.178
regulation of cellular amine metabolic process GO:0033238 11 0.171
nucleobase catabolic process GO:0046113 4 0.134
positive regulation of cellular component organization GO:0051130 376 0.134
Human
cellular amino acid metabolic process GO:0006520 116 0.111
cellular amine metabolic process GO:0044106 41 0.097
regulation of cellular amino acid metabolic process GO:0006521 6 0.066
positive regulation of cellular amine metabolic process GO:0033240 7 0.066
vesicle mediated transport GO:0016192 371 0.064
plasma membrane organization GO:0007009 115 0.063
protein oligomerization GO:0051259 173 0.062
regulation of cellular ketone metabolic process GO:0010565 50 0.061
amine metabolic process GO:0009308 44 0.060
post embryonic development GO:0009791 2 0.058
Worm
cellular ketone metabolic process GO:0042180 80 0.055
membrane organization GO:0061024 292 0.052
single organism membrane organization GO:0044802 268 0.049
generation of neurons GO:0048699 152 0.045
Mouse Fly
endomembrane system organization GO:0010256 196 0.045
nucleoside catabolic process GO:0009164 408 0.044
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
Human
negative regulation of protein metabolic process GO:0051248 391 0.043
Human
neuron differentiation GO:0030182 138 0.043
Mouse Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
signal transduction by phosphorylation GO:0023014 297 0.042
Human
determination of adult lifespan GO:0008340 2 0.042
regulation of transferase activity GO:0051338 355 0.040
Human
positive regulation of cell proliferation GO:0008284 301 0.039
negative regulation of catalytic activity GO:0043086 335 0.039
Human
nucleotide catabolic process GO:0009166 408 0.038
cell development GO:0048468 328 0.037
Mouse Fly
regulation of kinase activity GO:0043549 314 0.037
Human
positive regulation of phosphorylation GO:0042327 394 0.037
positive regulation of protein complex assembly GO:0031334 86 0.037
positive regulation of protein phosphorylation GO:0001934 313 0.037
regulation of cellular component biogenesis GO:0044087 281 0.036
Human
neuron development GO:0048666 113 0.036
Mouse Fly
oogenesis GO:0048477 2 0.036
multicellular organismal aging GO:0010259 3 0.036
dephosphorylation GO:0016311 209 0.035
female gamete generation GO:0007292 2 0.035
positive regulation of hydrolase activity GO:0051345 331 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.034
positive regulation of cellular component biogenesis GO:0044089 158 0.034
Human
ribonucleotide catabolic process GO:0009261 405 0.034
regeneration GO:0031099 4 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.033
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.032
cytoplasmic transport GO:0016482 379 0.031
positive regulation of protein oligomerization GO:0032461 17 0.031
regulation of protein kinase activity GO:0045859 289 0.031
Human
actin filament based process GO:0030029 224 0.031
cation transport GO:0006812 331 0.031
lipid metabolic process GO:0006629 381 0.030
cell projection organization GO:0030030 252 0.030
Mouse Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.030
nucleobase metabolic process GO:0009112 8 0.030
endocytosis GO:0006897 159 0.030
nucleoside triphosphate metabolic process GO:0009141 422 0.030
glycosyl compound catabolic process GO:1901658 413 0.029
peptidyl tyrosine modification GO:0018212 170 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
regulation of cell migration GO:0030334 289 0.029
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.028
Human
response to abiotic stimulus GO:0009628 336 0.028
purine nucleoside catabolic process GO:0006152 398 0.028
regulation of anatomical structure morphogenesis GO:0022603 286 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
neurogenesis GO:0022008 169 0.028
Mouse Fly
purine ribonucleoside metabolic process GO:0046128 437 0.028
mapk cascade GO:0000165 288 0.027
Human
cellular macromolecular complex assembly GO:0034622 324 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
Human
chemical homeostasis GO:0048878 306 0.027
biological adhesion GO:0022610 331 0.027
Human
system process GO:0003008 349 0.026
Human Mouse Rat Fly
positive regulation of transferase activity GO:0051347 227 0.026
pyrimidine nucleobase catabolic process GO:0006208 3 0.026
transmembrane transport GO:0055085 399 0.026
negative regulation of cell death GO:0060548 345 0.026
locomotory behavior GO:0007626 1 0.025
regulation of protein localization GO:0032880 296 0.025
cellular homeostasis GO:0019725 196 0.025
photoreceptor cell differentiation GO:0046530 2 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.025
Human
purine nucleotide catabolic process GO:0006195 405 0.025
peptidyl tyrosine phosphorylation GO:0018108 170 0.025
single organism carbohydrate metabolic process GO:0044723 193 0.025
positive regulation of mapk cascade GO:0043410 190 0.025
negative regulation of cellular amine metabolic process GO:0033239 3 0.024
purine containing compound catabolic process GO:0072523 411 0.024
segmentation GO:0035282 4 0.024
cellular chemical homeostasis GO:0055082 180 0.024
ion homeostasis GO:0050801 230 0.024
metal ion homeostasis GO:0055065 169 0.024
negative regulation of phosphorylation GO:0042326 174 0.024
Human
neurological system process GO:0050877 163 0.023
Fly
protein maturation GO:0051604 233 0.023
cellular lipid metabolic process GO:0044255 303 0.023
cell activation GO:0001775 213 0.023
organic hydroxy compound metabolic process GO:1901615 147 0.023
response to oxygen containing compound GO:1901700 369 0.023
mitotic cell cycle GO:0000278 326 0.023
monocarboxylic acid metabolic process GO:0032787 185 0.023
ras protein signal transduction GO:0007265 73 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
neuromuscular junction development GO:0007528 3 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
defense response GO:0006952 315 0.022
regulation of locomotion GO:0040012 329 0.022
Human
protein localization to organelle GO:0033365 280 0.022
regulation of proteolysis GO:0030162 293 0.022
microtubule based process GO:0007017 210 0.022
purine ribonucleotide catabolic process GO:0009154 404 0.022
metal ion transport GO:0030001 272 0.022
single organism cellular localization GO:1902580 332 0.022
organelle localization GO:0051640 84 0.022
cyclic nucleotide metabolic process GO:0009187 82 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
adult locomotory behavior GO:0008344 1 0.021
hindbrain development GO:0030902 3 0.021
nucleoside phosphate biosynthetic process GO:1901293 109 0.021
cation homeostasis GO:0055080 189 0.021
maintenance of location GO:0051235 112 0.021
receptor internalization GO:0031623 43 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
memory GO:0007613 3 0.021
Fly
cellular response to endogenous stimulus GO:0071495 336 0.021
membrane tubulation GO:0097320 12 0.021
positive regulation of kinase activity GO:0033674 204 0.021
cell cell signaling GO:0007267 155 0.020
regulation of protein oligomerization GO:0032459 26 0.020
cellular component morphogenesis GO:0032989 314 0.020
Mouse Fly
positive regulation of catabolic process GO:0009896 310 0.020
innate immune response GO:0045087 178 0.020
cation transmembrane transport GO:0098655 238 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
regulation of cell differentiation GO:0045595 393 0.020
positive regulation of immune system process GO:0002684 283 0.020
Human
peripheral nervous system development GO:0007422 2 0.020
organophosphate catabolic process GO:0046434 430 0.020
negative regulation of transport GO:0051051 176 0.020
establishment of organelle localization GO:0051656 59 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
blood coagulation GO:0007596 76 0.020
negative regulation of protein modification process GO:0031400 200 0.020
Human
regulation of mapk cascade GO:0043408 262 0.020
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
positive regulation of organelle organization GO:0010638 195 0.020
sequestering of metal ion GO:0051238 24 0.020
regulation of intracellular transport GO:0032386 195 0.020
neuroblast proliferation GO:0007405 4 0.019
purine nucleoside monophosphate catabolic process GO:0009128 158 0.019
negative regulation of locomotion GO:0040013 118 0.019
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
cellular protein catabolic process GO:0044257 261 0.019
cell adhesion GO:0007155 325 0.019
Human
long term memory GO:0007616 2 0.019
Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
cellular ion homeostasis GO:0006873 168 0.019
protein processing GO:0016485 226 0.019
oocyte development GO:0048599 1 0.019
calcium ion transport GO:0006816 147 0.019
mitotic cell cycle process GO:1903047 286 0.019
receptor metabolic process GO:0043112 81 0.019
regulation of cell adhesion GO:0030155 166 0.019
Human
cytokine production GO:0001816 247 0.019
oocyte differentiation GO:0009994 2 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
synaptic transmission GO:0007268 61 0.019
positive regulation of protein kinase activity GO:0045860 190 0.018
nucleotide biosynthetic process GO:0009165 109 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.018
spermatid differentiation GO:0048515 4 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.018
anterior posterior axis specification GO:0009948 2 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
response to radiation GO:0009314 151 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
intracellular protein transport GO:0006886 270 0.018
tripartite regional subdivision GO:0007351 2 0.018
regulation of protein maturation GO:1903317 150 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
regulation of protein processing GO:0070613 150 0.018
response to wounding GO:0009611 168 0.018
negative regulation of multicellular organismal process GO:0051241 317 0.018
Rat Worm
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
Human
regulation of cell cycle GO:0051726 393 0.018
response to biotic stimulus GO:0009607 276 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
positive regulation of programmed cell death GO:0043068 249 0.017
lipid localization GO:0010876 106 0.017
leukocyte activation GO:0045321 164 0.017
circulatory system development GO:0072359 262 0.017
protein catabolic process GO:0030163 325 0.017
cell growth GO:0016049 160 0.017
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.017
nuclear transport GO:0051169 179 0.017
anion transport GO:0006820 161 0.017
regulation of cell cycle process GO:0010564 266 0.017
regulation of epithelial cell migration GO:0010632 93 0.017
pyrimidine containing compound metabolic process GO:0072527 19 0.017
anterior posterior axis specification embryo GO:0008595 2 0.017
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.017
blood vessel development GO:0001568 172 0.017
response to external biotic stimulus GO:0043207 261 0.017
divalent inorganic cation transport GO:0072511 158 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
asymmetric stem cell division GO:0098722 1 0.017
camp metabolic process GO:0046058 61 0.017
epithelium migration GO:0090132 119 0.017
establishment of vesicle localization GO:0051650 23 0.017
regulation of cell development GO:0060284 161 0.017
erk1 and erk2 cascade GO:0070371 104 0.017
regulation of response to external stimulus GO:0032101 222 0.017
rho protein signal transduction GO:0007266 26 0.017
epithelial cell migration GO:0010631 119 0.016
nucleoside monophosphate metabolic process GO:0009123 191 0.016
atp catabolic process GO:0006200 157 0.016
blood vessel morphogenesis GO:0048514 162 0.016
divalent metal ion transport GO:0070838 152 0.016
regulation of synaptic plasticity GO:0048167 3 0.016
sulfur compound metabolic process GO:0006790 101 0.016
atp metabolic process GO:0046034 176 0.016
regulation of cellular component movement GO:0051270 334 0.016
Human
immune response GO:0006955 307 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
Human
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
cell cycle phase transition GO:0044770 173 0.016
blastoderm segmentation GO:0007350 2 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
response to lipid GO:0033993 206 0.016
positive regulation of synaptic transmission GO:0050806 4 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
gamma aminobutyric acid signaling pathway GO:0007214 3 0.016
vasculature development GO:0001944 181 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
cell part morphogenesis GO:0032990 137 0.016
Mouse Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
regulation of cytokine production GO:0001817 232 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
negative regulation of developmental process GO:0051093 247 0.016
Worm
gtp catabolic process GO:0006184 237 0.016
negative regulation of proteolysis GO:0045861 132 0.016
positive regulation of cell migration GO:0030335 172 0.016
negative regulation of protein processing GO:0010955 142 0.016
compound eye development GO:0048749 1 0.015
single organism cell adhesion GO:0098602 179 0.015
cell division GO:0051301 168 0.015
rna processing GO:0006396 255 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
regulation of protein complex assembly GO:0043254 147 0.015
angiogenesis GO:0001525 147 0.015
nervous system development GO:0007399 293 0.015
Mouse Fly
regulation of meiotic cell cycle GO:0051445 4 0.015
response to other organism GO:0051707 261 0.015
apoptotic signaling pathway GO:0097190 268 0.015
lipid biosynthetic process GO:0008610 177 0.015
stem cell division GO:0017145 2 0.015
sequestering of calcium ion GO:0051208 17 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
negative regulation of transferase activity GO:0051348 124 0.015
Human
establishment of protein localization to organelle GO:0072594 172 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
actin mediated cell contraction GO:0070252 12 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
response to cytokine GO:0034097 232 0.015
lipid transport GO:0006869 90 0.015
response to hormone GO:0009725 175 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
regulation of secretion GO:0051046 194 0.014
regulation of protein transport GO:0051223 213 0.014
oxidation reduction process GO:0055114 396 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
organic anion transport GO:0015711 103 0.014
regulation of peptidase activity GO:0052547 180 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
carbohydrate metabolic process GO:0005975 207 0.014
cell type specific apoptotic process GO:0097285 125 0.014
glycoprotein metabolic process GO:0009100 110 0.014
alcohol metabolic process GO:0006066 114 0.014
immune system development GO:0002520 195 0.014
negative regulation of kinase activity GO:0033673 106 0.014
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.014
central nervous system development GO:0007417 123 0.014
Fly
inorganic ion transmembrane transport GO:0098660 231 0.014
regulation of cell motility GO:2000145 299 0.014
Human
endothelial cell migration GO:0043542 86 0.014
epithelial cell proliferation GO:0050673 128 0.014
organelle assembly GO:0070925 176 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
endosomal transport GO:0016197 129 0.014
growth GO:0040007 202 0.014
Human
cellular cation homeostasis GO:0030003 163 0.014
response to growth factor GO:0070848 205 0.014
lymphocyte activation GO:0046649 133 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
Human
regulation of dephosphorylation GO:0035303 96 0.014
protein targeting GO:0006605 187 0.014
cardiovascular system development GO:0072358 262 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.014
regulation of cell growth GO:0001558 135 0.013
Human
negative regulation of protein maturation GO:1903318 142 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
protein homooligomerization GO:0051260 100 0.013
cell fate determination GO:0001709 3 0.013
protein autophosphorylation GO:0046777 123 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
small molecule biosynthetic process GO:0044283 157 0.013
positive regulation of gliogenesis GO:0014015 4 0.013
organic acid biosynthetic process GO:0016053 97 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
negative regulation of organelle organization GO:0010639 126 0.013
regulation of immune response GO:0050776 201 0.013
Human
motor neuron axon guidance GO:0008045 2 0.013
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
mitochondrion organization GO:0007005 156 0.013
regulation of membrane potential GO:0042391 95 0.013
eye photoreceptor cell differentiation GO:0001754 2 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
nitrogen compound transport GO:0071705 191 0.013
regulation of glial cell proliferation GO:0060251 4 0.013
cellular divalent inorganic cation homeostasis GO:0072503 128 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
regulation of secretion by cell GO:1903530 177 0.013
response to nitrogen compound GO:1901698 184 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of map kinase activity GO:0043405 108 0.013
Human
reactive nitrogen species metabolic process GO:2001057 3 0.013
phospholipid metabolic process GO:0006644 99 0.013
regulation of ion transmembrane transport GO:0034765 132 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
Human
positive regulation of apoptotic process GO:0043065 246 0.013
neuronal stem cell division GO:0036445 1 0.013
positive regulation of cytokine production GO:0001819 167 0.013
protein localization to membrane GO:0072657 160 0.012
actin cytoskeleton organization GO:0030036 207 0.012
actin filament based movement GO:0030048 17 0.012
negative regulation of cell motility GO:2000146 104 0.012
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
epithelium development GO:0060429 227 0.012
Mouse
response to calcium ion GO:0051592 46 0.012
negative regulation of catabolic process GO:0009895 104 0.012
cellular response to organonitrogen compound GO:0071417 124 0.012
visual learning GO:0008542 1 0.012
response to fungus GO:0009620 4 0.012
tissue migration GO:0090130 119 0.012
calcium ion homeostasis GO:0055074 122 0.012
cellular carbohydrate metabolic process GO:0044262 84 0.012
calcium ion transmembrane transport GO:0070588 76 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
regulation of homeostatic process GO:0032844 121 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
nuclear import GO:0051170 106 0.012
mating GO:0007618 1 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
taxis GO:0042330 157 0.012
nucleus localization GO:0051647 1 0.012
response to organic cyclic compound GO:0014070 204 0.012
tissue regeneration GO:0042246 3 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
regulation of protein catabolic process GO:0042176 155 0.012
somatic muscle development GO:0007525 1 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
carboxylic acid transport GO:0046942 63 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
embryonic placenta development GO:0001892 1 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
primary neural tube formation GO:0014020 3 0.012
chromatin modification GO:0016568 298 0.012
regulation of metal ion transport GO:0010959 120 0.012
negative regulation of cellular component movement GO:0051271 106 0.012
Human
synaptic vesicle recycling GO:0036465 3 0.012
hemopoiesis GO:0030097 180 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.012
g protein coupled receptor signaling pathway GO:0007186 207 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
head development GO:0060322 108 0.012
regulation of cellular response to stress GO:0080135 244 0.012
cell morphogenesis GO:0000902 296 0.012
Mouse Fly
regulation of nucleoside metabolic process GO:0009118 209 0.012
regulation of gtp catabolic process GO:0033124 180 0.011
sensory perception GO:0007600 103 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
cerebellum development GO:0021549 2 0.011
fatty acid metabolic process GO:0006631 115 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
protein ubiquitination GO:0016567 314 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
spermatid development GO:0007286 4 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
response to metal ion GO:0010038 84 0.011
ameboidal type cell migration GO:0001667 135 0.011
somatic stem cell division GO:0048103 1 0.011
regulation of cell activation GO:0050865 125 0.011
limbic system development GO:0021761 3 0.011
regulation of dna metabolic process GO:0051052 153 0.011
gtp metabolic process GO:0046039 239 0.011
regulation of phosphatase activity GO:0010921 81 0.011
melanin metabolic process GO:0006582 1 0.011
dna repair GO:0006281 198 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
histone modification GO:0016570 251 0.011
regulation of vasculature development GO:1901342 97 0.011
cell substrate adhesion GO:0031589 132 0.011
Human
regulation of cytoplasmic transport GO:1903649 149 0.011
peptidyl serine modification GO:0018209 106 0.011
secretion GO:0046903 254 0.011
regulation of erk1 and erk2 cascade GO:0070372 99 0.011
positive regulation of developmental process GO:0051094 314 0.011
Worm
regulation of intracellular protein transport GO:0033157 123 0.011
rhythmic behavior GO:0007622 2 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
negative regulation of cell migration GO:0030336 102 0.011
Human
organic acid transport GO:0015849 65 0.011
response to axon injury GO:0048678 1 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
metencephalon development GO:0022037 2 0.011
regulation of transmembrane transport GO:0034762 139 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
somatic stem cell maintenance GO:0035019 4 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
neuroblast division GO:0055057 1 0.011
protein dephosphorylation GO:0006470 81 0.011
ion transmembrane transport GO:0034220 338 0.011
regulation of cell division GO:0051302 116 0.011
neuron projection development GO:0031175 106 0.011
Mouse Fly
positive regulation of cell death GO:0010942 263 0.011
actin filament organization GO:0007015 128 0.011
positive regulation of cell motility GO:2000147 177 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
response to bacterium GO:0009617 144 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
cell projection assembly GO:0030031 126 0.010
Mouse
negative regulation of cell cycle GO:0045786 193 0.010
cyclic nucleotide biosynthetic process GO:0009190 61 0.010
protein targeting to nucleus GO:0044744 104 0.010
neural tube formation GO:0001841 3 0.010
coagulation GO:0050817 78 0.010
mitotic nuclear division GO:0007067 119 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
wound healing GO:0042060 115 0.010
regulation of platelet aggregation GO:0090330 4 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
Mouse
cardiac muscle cell contraction GO:0086003 4 0.010
positive regulation of cell development GO:0010720 92 0.010
sensory perception of smell GO:0007608 2 0.010
cellular response to abiotic stimulus GO:0071214 117 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
regulation of synaptic vesicle exocytosis GO:2000300 2 0.010
meiotic chromosome segregation GO:0045132 4 0.010
covalent chromatin modification GO:0016569 254 0.010

PTPRO disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.024
cancer DOID:162 167 0.020
Human
disease of cellular proliferation DOID:14566 174 0.020
Human
organ system cancer DOID:0050686 164 0.020
Human
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
musculoskeletal system disease DOID:17 223 0.019
central nervous system disease DOID:331 186 0.018
disease of mental health DOID:150 70 0.016
eye and adnexa disease DOID:1492 150 0.015
inherited metabolic disorder DOID:655 242 0.015
cardiovascular system disease DOID:1287 106 0.014
immune system disease DOID:2914 155 0.014
eye disease DOID:5614 149 0.012
retinal disease DOID:5679 118 0.012
neurodegenerative disease DOID:1289 102 0.012
muscular disease DOID:0080000 114 0.010
neuropathy DOID:870 52 0.010