Homo sapiens

0 known processes

LASS2

LAG1 homolog, ceramide synthase 2

(Aliases: TMSG1,FLJ10243,MGC987,SP260,L3,CerS2)

LASS2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 238 0.936
transmembrane transport GO:0055085 399 0.887
metal ion homeostasis GO:0055065 169 0.757
cation homeostasis GO:0055080 189 0.715
ion transmembrane transport GO:0034220 338 0.654
ion homeostasis GO:0050801 230 0.613
inorganic cation transmembrane transport GO:0098662 194 0.597
inorganic ion transmembrane transport GO:0098660 231 0.561
cation transport GO:0006812 331 0.555
divalent inorganic cation homeostasis GO:0072507 136 0.452
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.445
zinc ion transport GO:0006829 9 0.440
calcium ion transmembrane transport GO:0070588 76 0.407
post embryonic development GO:0009791 2 0.366
chemical homeostasis GO:0048878 306 0.318
cellular calcium ion homeostasis GO:0006874 117 0.280
negative regulation of apoptotic process GO:0043066 316 0.273
calcium ion homeostasis GO:0055074 122 0.267
metal ion transport GO:0030001 272 0.258
locomotory behavior GO:0007626 1 0.246
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.245
cellular cation homeostasis GO:0030003 163 0.235
regulation of apoptotic signaling pathway GO:2001233 175 0.222
intrinsic apoptotic signaling pathway GO:0097193 127 0.217
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.215
negative regulation of apoptotic signaling pathway GO:2001234 97 0.203
apoptotic signaling pathway GO:0097190 268 0.183
response to endoplasmic reticulum stress GO:0034976 49 0.179
cellular ion homeostasis GO:0006873 168 0.162
regulation of cellular response to stress GO:0080135 244 0.152
cellular chemical homeostasis GO:0055082 180 0.152
cellular divalent inorganic cation homeostasis GO:0072503 128 0.152
monocarboxylic acid metabolic process GO:0032787 185 0.152
negative regulation of programmed cell death GO:0043069 321 0.146
response to fungus GO:0009620 4 0.144
vesicle mediated transport GO:0016192 371 0.142
cellular lipid metabolic process GO:0044255 303 0.124
Human Yeast Mouse
cellular homeostasis GO:0019725 196 0.124
transition metal ion homeostasis GO:0055076 31 0.123
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.119
zinc ion transmembrane import GO:0071578 2 0.119
female gamete generation GO:0007292 2 0.104
lipid biosynthetic process GO:0008610 177 0.103
Human Yeast Mouse
negative regulation of intracellular signal transduction GO:1902532 183 0.096
positive regulation of cell death GO:0010942 263 0.088
cellular metal ion homeostasis GO:0006875 146 0.086
transition metal ion transport GO:0000041 23 0.080
syncytium formation by plasma membrane fusion GO:0000768 2 0.078
embryonic retina morphogenesis in camera type eye GO:0060059 1 0.072
divalent metal ion transport GO:0070838 152 0.072
regulation of cellular amino acid metabolic process GO:0006521 6 0.066
very long chain fatty acid biosynthetic process GO:0042761 7 0.065
zinc ion homeostasis GO:0055069 12 0.062
protein glycosylation GO:0006486 62 0.059
response to other organism GO:0051707 261 0.059
glycoprotein biosynthetic process GO:0009101 91 0.059
endoplasmic reticulum calcium ion homeostasis GO:0032469 9 0.057
wnt signaling pathway GO:0016055 156 0.055
fatty acid metabolic process GO:0006631 115 0.052
lipid metabolic process GO:0006629 381 0.051
Human Yeast Mouse
amine metabolic process GO:0009308 44 0.051
determination of adult lifespan GO:0008340 2 0.050
regulation of protein kinase activity GO:0045859 289 0.049
carboxylic acid biosynthetic process GO:0046394 97 0.048
fatty acid elongation GO:0030497 8 0.047
glycoprotein metabolic process GO:0009100 110 0.046
regulation of kinase activity GO:0043549 314 0.046
organic acid biosynthetic process GO:0016053 97 0.046
fatty acid elongation polyunsaturated fatty acid GO:0034626 4 0.043
anion transport GO:0006820 161 0.043
positive regulation of necrotic cell death GO:0010940 4 0.041
response to external biotic stimulus GO:0043207 261 0.040
small molecule biosynthetic process GO:0044283 157 0.040
positive regulation of programmed cell death GO:0043068 249 0.039
membrane lipid metabolic process GO:0006643 53 0.039
Human Yeast Mouse
fatty acid elongation monounsaturated fatty acid GO:0034625 3 0.039
peripheral nervous system development GO:0007422 2 0.038
cell development GO:0048468 328 0.038
homeostasis of number of cells in a free living population GO:0048874 1 0.038
cellular amine metabolic process GO:0044106 41 0.038
regulation of transferase activity GO:0051338 355 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.034
urate transport GO:0015747 3 0.034
regulation of transmembrane transport GO:0034762 139 0.034
sphingolipid metabolic process GO:0006665 38 0.032
Human Yeast Mouse
regulation of wnt signaling pathway GO:0030111 123 0.032
regulation of ion transmembrane transport GO:0034765 132 0.032
response to biotic stimulus GO:0009607 276 0.031
organonitrogen compound biosynthetic process GO:1901566 200 0.029
Human Yeast Mouse
negative regulation of protein metabolic process GO:0051248 391 0.029
organic anion transport GO:0015711 103 0.029
fatty acid biosynthetic process GO:0006633 46 0.028
system process GO:0003008 349 0.028
intracellular protein transport GO:0006886 270 0.027
oocyte differentiation GO:0009994 2 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
monocarboxylic acid biosynthetic process GO:0072330 67 0.025
positive regulation of intestinal epithelial structure maintenance GO:0060731 1 0.025
cellular amino acid metabolic process GO:0006520 116 0.025
chloride transport GO:0006821 41 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
positive regulation of developmental process GO:0051094 314 0.023
oxidation reduction process GO:0055114 396 0.023
regulation of ion transport GO:0043269 189 0.023
single organism cellular localization GO:1902580 332 0.023
anion transmembrane transport GO:0098656 76 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
aging GO:0007568 66 0.022
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.022
chloride transmembrane transport GO:1902476 38 0.022
cell adhesion GO:0007155 325 0.021
mapk cascade GO:0000165 288 0.021
memory GO:0007613 3 0.021
renal tubular secretion GO:0097254 1 0.021
negative regulation of catalytic activity GO:0043086 335 0.020
cellular ketone metabolic process GO:0042180 80 0.020
very long chain fatty acid metabolic process GO:0000038 19 0.020
secretion by cell GO:0032940 226 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
nitrogen compound transport GO:0071705 191 0.019
adult behavior GO:0030534 18 0.018
regulation of proteolysis GO:0030162 293 0.018
membrane lipid biosynthetic process GO:0046467 27 0.018
Human Yeast Mouse
positive regulation of wnt signaling pathway GO:0030177 54 0.018
single organism reproductive process GO:0044702 98 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
lipid modification GO:0030258 84 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
tissue morphogenesis GO:0048729 96 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
biological adhesion GO:0022610 331 0.017
sodium independent organic anion transport GO:0043252 2 0.017
carnitine transmembrane transport GO:1902603 3 0.017
regulation of protein serine threonine kinase activity GO:0071900 179 0.017
phospholipid metabolic process GO:0006644 99 0.017
regulation of mapk cascade GO:0043408 262 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
immune system development GO:0002520 195 0.016
quorum sensing involved in interaction with host GO:0052106 1 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
positive regulation of catabolic process GO:0009896 310 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
regulation of cell differentiation GO:0045595 393 0.016
carbohydrate metabolic process GO:0005975 207 0.016
oocyte development GO:0048599 1 0.016
mating GO:0007618 1 0.016
hindbrain development GO:0030902 3 0.016
short chain fatty acid import GO:0015913 1 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
ras protein signal transduction GO:0007265 73 0.016
alpha ketoglutarate transport GO:0015742 1 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
necrotic cell death GO:0070265 21 0.015
alcohol metabolic process GO:0006066 114 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
vacuole organization GO:0007033 44 0.015
blood circulation GO:0008015 113 0.015
segmentation GO:0035282 4 0.014
sphingolipid biosynthetic process GO:0030148 18 0.014
Human Yeast Mouse
multicellular organismal aging GO:0010259 3 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
exocytosis GO:0006887 71 0.014
neurotransmitter secretion GO:0007269 4 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
cellular protein complex assembly GO:0043623 188 0.014
regulation of protein localization GO:0032880 296 0.014
neuron differentiation GO:0030182 138 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
cellular component morphogenesis GO:0032989 314 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
ribonucleoside monophosphate catabolic process GO:0009158 158 0.013
cytoplasmic transport GO:0016482 379 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
synaptic vesicle recycling GO:0036465 3 0.013
positive regulation of transferase activity GO:0051347 227 0.013
glycosylation GO:0070085 71 0.013
sodium ion transport GO:0006814 61 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
tissue homeostasis GO:0001894 63 0.013
motor neuron axon guidance GO:0008045 2 0.013
macromolecule glycosylation GO:0043413 63 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
carboxylic acid transport GO:0046942 63 0.013
protein oligomerization GO:0051259 173 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
receptor mediated endocytosis GO:0006898 84 0.013
organelle assembly GO:0070925 176 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
nucleotide catabolic process GO:0009166 408 0.012
protein homooligomerization GO:0051260 100 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
anatomical structure homeostasis GO:0060249 100 0.012
regulation of protein catabolic process GO:0042176 155 0.012
nicotinate transport GO:2001142 1 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
protein import GO:0017038 130 0.012
midbrain development GO:0030901 45 0.012
organ morphogenesis GO:0009887 147 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
ossification GO:0001503 121 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
response to abiotic stimulus GO:0009628 336 0.012
protein catabolic process GO:0030163 325 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
reproduction GO:0000003 63 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.011
protein localization to membrane GO:0072657 160 0.011
negative regulation of transferase activity GO:0051348 124 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
neurological system process GO:0050877 163 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
nucleoside catabolic process GO:0009164 408 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
negative regulation of cell cycle GO:0045786 193 0.011
atp catabolic process GO:0006200 157 0.011
spermatid differentiation GO:0048515 4 0.011
protein maturation GO:0051604 233 0.011
inorganic anion transmembrane transport GO:0098661 47 0.011
quorum sensing GO:0009372 1 0.011
regulation of cell motility GO:2000145 299 0.011
regulation of peptidase activity GO:0052547 180 0.011
hematopoietic stem cell differentiation GO:0060218 4 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
positive regulation of kinase activity GO:0033674 204 0.011
secretion GO:0046903 254 0.011
myosin filament assembly GO:0031034 2 0.011
negative regulation of protein modification process GO:0031400 200 0.011
cell growth GO:0016049 160 0.011
behavior GO:0007610 112 0.011
mitotic cell cycle GO:0000278 326 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
cilium morphogenesis GO:0060271 75 0.011
endomembrane system organization GO:0010256 196 0.010
inorganic anion transport GO:0015698 60 0.010
oogenesis GO:0048477 2 0.010
hemopoiesis GO:0030097 180 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
response to axon injury GO:0048678 1 0.010
sensory perception of pain GO:0019233 4 0.010
protein targeting GO:0006605 187 0.010
regulation of protein transport GO:0051223 213 0.010
regulation of cellular component movement GO:0051270 334 0.010
negative regulation of kinase activity GO:0033673 106 0.010
interspecies quorum sensing GO:0052097 1 0.010
multi organism cellular process GO:0044764 156 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
head development GO:0060322 108 0.010
sensory organ morphogenesis GO:0090596 21 0.010
central nervous system development GO:0007417 123 0.010
actin filament based movement GO:0030048 17 0.010
morphogenesis of a polarized epithelium GO:0001738 3 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
myosin filament organization GO:0031033 2 0.010

LASS2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.068
inherited metabolic disorder DOID:655 242 0.026
immune system disease DOID:2914 155 0.019
disease of cellular proliferation DOID:14566 174 0.011
central nervous system disease DOID:331 186 0.011
neurodegenerative disease DOID:1289 102 0.011
nervous system disease DOID:863 431 0.011
carbohydrate metabolic disorder DOID:2978 55 0.011