Homo sapiens

32 known processes

IFIT2

interferon-induced protein with tetratricopeptide repeats 2

(Aliases: IFI-54K,IFIT-2,IFI-54,ISG54,ISG-54 K,cig42,GARG-39,G10P2,IFI54,ISG-54K)

IFIT2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular transport of viral protein in host cell GO:0019060 4 1.000
Human
regulation by virus of viral protein levels in host cell GO:0046719 4 0.995
Human
intracellular transport of virus GO:0075733 14 0.993
Human
extracellular transport GO:0006858 4 0.984
Human
cellular response to interferon alpha GO:0035457 4 0.982
Mouse
negative regulation of defense response to virus by host GO:0050689 4 0.979
Human
regulation of viral process GO:0050792 103 0.964
Human
transport of virus GO:0046794 14 0.959
Human
intracellular protein transport in other organism involved in symbiotic interaction GO:0051708 4 0.944
Human
cellular response to dsrna GO:0071359 19 0.922
Human
defense response to virus GO:0051607 71 0.919
Human
symbiont intracellular protein transport in host GO:0030581 4 0.917
Human
response to biotic stimulus GO:0009607 276 0.914
regulation of viral genome replication GO:0045069 48 0.914
Human
multi organism cellular process GO:0044764 156 0.912
Human
regulation of defense response to virus GO:0050688 33 0.908
Human
response to external biotic stimulus GO:0043207 261 0.898
negative regulation of viral genome replication GO:0045071 35 0.890
Human
response to cytokine GO:0034097 232 0.889
Human Mouse
viral life cycle GO:0019058 132 0.888
Human
defense response GO:0006952 315 0.868
Human
response to interferon alpha GO:0035455 11 0.867
Mouse
response to phenylpropanoid GO:0080184 1 0.853
regulation of immune effector process GO:0002697 91 0.830
Human
regulation of multi organism process GO:0043900 157 0.826
Human
response to virus GO:0009615 126 0.808
interspecies interaction between organisms GO:0044419 156 0.801
Human
regulation of defense response to virus by host GO:0050691 22 0.797
Human
defense response to other organism GO:0098542 129 0.792
Human
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.774
Human
chemical homeostasis GO:0048878 306 0.771
Human
response to other organism GO:0051707 261 0.763
cellular response to cytokine stimulus GO:0071345 181 0.737
Human Mouse
negative regulation of viral process GO:0048525 66 0.722
Human
regulation of defense response GO:0031347 154 0.720
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.719
Human
immune effector process GO:0002252 159 0.701
Human
viral genome replication GO:0019079 50 0.674
Human
negative regulation of defense response to virus GO:0050687 10 0.629
Human
innate immune response GO:0045087 178 0.624
Human
negative regulation of multi organism process GO:0043901 92 0.569
Human
viral process GO:0016032 146 0.523
Human
multi organism transport GO:0044766 14 0.499
Human
immune response GO:0006955 307 0.479
Human
positive regulation of programmed cell death GO:0043068 249 0.459
negative regulation of cell proliferation GO:0008285 228 0.438
Human
positive regulation of rig i signaling pathway GO:1900246 4 0.435
negative regulation of response to external stimulus GO:0032102 83 0.434
Human
negative regulation of apoptotic process GO:0043066 316 0.433
Human
nucleoside phosphate biosynthetic process GO:1901293 109 0.420
cellular response to organic cyclic compound GO:0071407 127 0.384
Human
response to nitrogen compound GO:1901698 184 0.384
Human
multi organism intracellular transport GO:1902583 14 0.382
Human
regulation of response to biotic stimulus GO:0002831 55 0.377
Human
regulation of protein binding GO:0043393 66 0.368
glycosylation GO:0070085 71 0.350
cellular response to type i interferon GO:0071357 12 0.345
Human
response to dsrna GO:0043331 25 0.333
Human
negative regulation of defense response GO:0031348 47 0.326
Human
interaction with host GO:0051701 42 0.314
Human
positive regulation of apoptotic process GO:0043065 246 0.314
negative regulation of immune system process GO:0002683 136 0.313
Human
positive regulation of viral process GO:0048524 37 0.313
Human
positive regulation of cell death GO:0010942 263 0.311
negative regulation of binding GO:0051100 57 0.296
negative regulation of cell death GO:0060548 345 0.294
Human
multi organism localization GO:1902579 14 0.292
Human
cellular response to interferon beta GO:0035458 6 0.288
negative regulation of immune effector process GO:0002698 38 0.287
Human
negative regulation of programmed cell death GO:0043069 321 0.284
Human
cellular response to exogenous dsrna GO:0071360 5 0.261
Human
negative regulation of helicase activity GO:0051097 2 0.239
Human
response to organic cyclic compound GO:0014070 204 0.239
Human
intracellular protein transport GO:0006886 270 0.230
Human
regulation of response to external stimulus GO:0032101 222 0.229
Human
negative regulation of protein binding GO:0032091 35 0.214
negative regulation of response to biotic stimulus GO:0002832 18 0.205
Human
negative regulation of catalytic activity GO:0043086 335 0.189
Human
organophosphate biosynthetic process GO:0090407 163 0.180
glycoprotein biosynthetic process GO:0009101 91 0.148
protein oligomerization GO:0051259 173 0.146
positive regulation of multi organism process GO:0043902 56 0.144
Human
regulation of binding GO:0051098 111 0.130
regulation of protein transport GO:0051223 213 0.123
immune system development GO:0002520 195 0.120
regulation of ribonuclease activity GO:0060700 3 0.115
response to type i interferon GO:0034340 14 0.109
Human
regulation of helicase activity GO:0051095 8 0.099
Human
cellular response to nitrogen compound GO:1901699 144 0.098
Human
positive regulation of interferon beta production GO:0032728 17 0.095
nucleotide biosynthetic process GO:0009165 109 0.093
protein myristoylation GO:0018377 1 0.086
hemopoiesis GO:0030097 180 0.086
single organism carbohydrate metabolic process GO:0044723 193 0.084
lipoprotein metabolic process GO:0042157 42 0.083
response to exogenous dsrna GO:0043330 10 0.081
Human
nuclear transport GO:0051169 179 0.079
organonitrogen compound biosynthetic process GO:1901566 200 0.077
protein glycosylation GO:0006486 62 0.077
negative regulation of hydrolase activity GO:0051346 182 0.072
Human
purine nucleotide biosynthetic process GO:0006164 84 0.065
carbohydrate derivative biosynthetic process GO:1901137 207 0.065
regulation of transferase activity GO:0051338 355 0.062
biological adhesion GO:0022610 331 0.057
positive regulation of immune system process GO:0002684 283 0.056
positive regulation of viral genome replication GO:0045070 15 0.055
Human
regulation of rig i signaling pathway GO:0039535 6 0.051
positive regulation of intracellular protein transport GO:0090316 76 0.050
positive regulation of cell differentiation GO:0045597 211 0.048
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.046
protein acylation GO:0043543 138 0.046
glycoprotein metabolic process GO:0009100 110 0.044
negative regulation of protein metabolic process GO:0051248 391 0.044
gene silencing by rna GO:0031047 26 0.041
ion homeostasis GO:0050801 230 0.041
organophosphate catabolic process GO:0046434 430 0.040
nucleoside triphosphate metabolic process GO:0009141 422 0.040
regulation of locomotion GO:0040012 329 0.040
glucose metabolic process GO:0006006 45 0.040
purine containing compound biosynthetic process GO:0072522 88 0.039
macromolecule glycosylation GO:0043413 63 0.038
coagulation GO:0050817 78 0.037
regulation of t helper 2 cell cytokine production GO:2000551 2 0.037
regulation of mda 5 signaling pathway GO:0039533 4 0.037
calcium ion homeostasis GO:0055074 122 0.037
posttranscriptional gene silencing GO:0016441 25 0.036
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
t helper 2 cell cytokine production GO:0035745 3 0.033
mapk cascade GO:0000165 288 0.033
positive regulation of defense response GO:0031349 87 0.033
cellular response to oxygen containing compound GO:1901701 276 0.033
cation transport GO:0006812 331 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.031
positive regulation of homeostatic process GO:0032846 47 0.031
purine ribonucleotide catabolic process GO:0009154 404 0.030
glucose homeostasis GO:0042593 31 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
single organism cellular localization GO:1902580 332 0.029
monosaccharide metabolic process GO:0005996 74 0.029
cellular amino acid metabolic process GO:0006520 116 0.029
cytoplasmic transport GO:0016482 379 0.028
cellular metal ion homeostasis GO:0006875 146 0.027
multi organism metabolic process GO:0044033 41 0.027
positive regulation of locomotion GO:0040017 186 0.027
regulation of nuclease activity GO:0032069 11 0.027
modification dependent macromolecule catabolic process GO:0043632 212 0.025
nucleotide catabolic process GO:0009166 408 0.025
response to abiotic stimulus GO:0009628 336 0.025
cytokine production GO:0001816 247 0.025
positive regulation of immune response GO:0050778 159 0.024
purine containing compound catabolic process GO:0072523 411 0.024
positive regulation of transport GO:0051050 336 0.024
regulation of protein localization GO:0032880 296 0.024
response to molecule of bacterial origin GO:0002237 82 0.023
protein localization to nucleus GO:0034504 136 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
system process GO:0003008 349 0.023
cation homeostasis GO:0055080 189 0.023
carbohydrate metabolic process GO:0005975 207 0.023
protein ubiquitination GO:0016567 314 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
metal ion homeostasis GO:0055065 169 0.022
determination of adult lifespan GO:0008340 2 0.022
regulation of intracellular transport GO:0032386 195 0.022
regulation of nucleocytoplasmic transport GO:0046822 98 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
lipid metabolic process GO:0006629 381 0.021
multicellular organismal aging GO:0010259 3 0.021
regulation of dna metabolic process GO:0051052 153 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.021
metal ion transport GO:0030001 272 0.021
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.020
positive regulation of transferase activity GO:0051347 227 0.020
chemotaxis GO:0006935 157 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
blood coagulation GO:0007596 76 0.019
positive regulation of developmental process GO:0051094 314 0.019
glycerophospholipid metabolic process GO:0006650 84 0.019
single organism nuclear import GO:1902593 104 0.019
negative regulation of mitochondrial depolarization GO:0051902 2 0.019
cellular chemical homeostasis GO:0055082 180 0.019
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
alcohol metabolic process GO:0006066 114 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
response to growth factor GO:0070848 205 0.019
regulation of mhc class ii biosynthetic process GO:0045346 4 0.019
protein targeting GO:0006605 187 0.018
regulation of ion transport GO:0043269 189 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
single organism membrane organization GO:0044802 268 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
mhc class ii biosynthetic process GO:0045342 4 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
rna interference GO:0016246 4 0.017
regulation of cell differentiation GO:0045595 393 0.017
positive regulation of organelle organization GO:0010638 195 0.016
protein import GO:0017038 130 0.016
maintenance of location GO:0051235 112 0.016
glycosyl compound catabolic process GO:1901658 413 0.016
protein localization to organelle GO:0033365 280 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
positive regulation of protein phosphorylation GO:0001934 313 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
interferon gamma production GO:0032609 39 0.016
nucleoside catabolic process GO:0009164 408 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
leukocyte differentiation GO:0002521 98 0.016
glycerolipid metabolic process GO:0046486 107 0.016
cellular lipid metabolic process GO:0044255 303 0.015
actin filament based process GO:0030029 224 0.015
protein maturation GO:0051604 233 0.015
response to mechanical stimulus GO:0009612 51 0.015
cellular cation homeostasis GO:0030003 163 0.015
sequestering of metal ion GO:0051238 24 0.015
regulation of actin cytoskeleton organization GO:0032956 116 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
hexose metabolic process GO:0019318 55 0.015
response to bacterium GO:0009617 144 0.015
secretion GO:0046903 254 0.015
cell adhesion GO:0007155 325 0.015
circulatory system development GO:0072359 262 0.015
vasculature development GO:0001944 181 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
receptor metabolic process GO:0043112 81 0.014
regulation of secretion by cell GO:1903530 177 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
membrane organization GO:0061024 292 0.014
negative regulation of protein maturation GO:1903318 142 0.014
myoblast fusion GO:0007520 1 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
small molecule biosynthetic process GO:0044283 157 0.014
secretion by cell GO:0032940 226 0.014
positive regulation of intracellular transport GO:0032388 104 0.014
myeloid cell differentiation GO:0030099 117 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
regulation of cell adhesion GO:0030155 166 0.014
regulation of body fluid levels GO:0050878 99 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.013
protein localization to membrane GO:0072657 160 0.013
response to oxygen containing compound GO:1901700 369 0.013
mrna processing GO:0006397 133 0.013
cellular ion homeostasis GO:0006873 168 0.013
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 3 0.013
positive regulation of innate immune response GO:0045089 79 0.013
positive regulation of response to external stimulus GO:0032103 88 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
regulation of angiogenesis GO:0045765 92 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
regulation of protein import into nucleus GO:0042306 78 0.013
defense response to bacterium GO:0042742 63 0.013
ras protein signal transduction GO:0007265 73 0.013
cell fate determination GO:0001709 3 0.013
cellular protein catabolic process GO:0044257 261 0.013
protein catabolic process GO:0030163 325 0.013
vesicle mediated transport GO:0016192 371 0.013
positive regulation of catabolic process GO:0009896 310 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
protein lipidation GO:0006497 33 0.013
cellular divalent inorganic cation homeostasis GO:0072503 128 0.013
regulation of cell migration GO:0030334 289 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
protein import into nucleus GO:0006606 104 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
lipid biosynthetic process GO:0008610 177 0.012
female gamete generation GO:0007292 2 0.012
negative regulation of protein modification process GO:0031400 200 0.012
release of cytochrome c from mitochondria GO:0001836 35 0.012
positive regulation of cell motility GO:2000147 177 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
apoptotic signaling pathway GO:0097190 268 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
regulation of cellular response to stress GO:0080135 244 0.012
mda 5 signaling pathway GO:0039530 4 0.012
positive regulation of camp metabolic process GO:0030816 41 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
positive regulation of proteolysis GO:0045862 142 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
neuroblast proliferation GO:0007405 4 0.012
regulation of cell development GO:0060284 161 0.012
lipoprotein biosynthetic process GO:0042158 33 0.012
ribonucleotide biosynthetic process GO:0009260 81 0.012
lymphocyte differentiation GO:0030098 35 0.012
rho protein signal transduction GO:0007266 26 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
regulation of chromosome organization GO:0033044 103 0.011
response to lipid GO:0033993 206 0.011
regulation of homeostatic process GO:0032844 121 0.011
carbohydrate homeostasis GO:0033500 31 0.011
cardiovascular system development GO:0072358 262 0.011
receptor internalization GO:0031623 43 0.011
positive regulation of kinase activity GO:0033674 204 0.011
organic acid biosynthetic process GO:0016053 97 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
response to wounding GO:0009611 168 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
memory GO:0007613 3 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
protein targeting to nucleus GO:0044744 104 0.011
regulation of peptidase activity GO:0052547 180 0.011
cellular response to molecule of bacterial origin GO:0071219 62 0.011
hemostasis GO:0007599 76 0.011
regulation of lymphocyte mediated immunity GO:0002706 33 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
neurological system process GO:0050877 163 0.011
regulation of cell motility GO:2000145 299 0.011
regulation of actin filament based process GO:0032970 141 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
regulation of protein kinase activity GO:0045859 289 0.010
mating GO:0007618 1 0.010
detection of chemical stimulus GO:0009593 55 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
endocytosis GO:0006897 159 0.010
phospholipid metabolic process GO:0006644 99 0.010
transmembrane transport GO:0055085 399 0.010
regulation of map kinase activity GO:0043405 108 0.010
taxis GO:0042330 157 0.010
ribonucleoside triphosphate metabolic process GO:0009199 412 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
regulation of membrane potential GO:0042391 95 0.010

IFIT2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
sensory system disease DOID:0050155 203 0.015
disease of metabolism DOID:0014667 295 0.014
cancer DOID:162 167 0.011
disease of cellular proliferation DOID:14566 174 0.011